MeSH term | MeSH ID | Detail |
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Lung Neoplasms | D008175 | 171 associated lipids |
Body Weight | D001835 | 333 associated lipids |
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Huang M et al. | Single nucleotide polymorphism of CYP3A4 intron 2 and its influence on CYP3A4 mRNA expression and liver enzymatic activity in human liver. | 2015 | J. Huazhong Univ. Sci. Technol. Med. Sci. | pmid:26223917 |
Schneider SC et al. | Antibiotic Susceptibility and Sequence Type Distribution of Ureaplasma Species Isolated from Genital Samples in Switzerland. | 2015 | Antimicrob. Agents Chemother. | pmid:26195516 |
Takagi M et al. | Underlying mechanism of drug-drug interaction between pioglitazone and gemfibrozil: Gemfibrozil acyl-glucuronide is a mechanism-based inhibitor of CYP2C8. | 2015 | Drug Metab. Pharmacokinet. | pmid:26195223 |
Aydin S et al. | Development of antibiotic resistance genes in microbial communities during long-term operation of anaerobic reactors in the treatment of pharmaceutical wastewater. | 2015 | Water Res. | pmid:26188597 |
Gaudreau C et al. | Long-Lasting Outbreak of Erythromycin- and Ciprofloxacin-Resistant Campylobacter jejuni Subspecies jejuni From 2003 to 2013 in Men Who Have Sex With Men, Quebec, Canada. | 2015 | Clin. Infect. Dis. | pmid:26187024 |
Fayed B et al. | Multiplexed integrating plasmids for engineering of the erythromycin gene cluster for expression in Streptomyces spp. and combinatorial biosynthesis. | 2015 | Appl. Environ. Microbiol. | pmid:26431970 |
Haenen CC et al. | [Rosacea fulminans in pregnancy]. | 2015 | Ned Tijdschr Geneeskd | pmid:26058762 |
Gagliotti C et al. | A regionwide intervention to promote appropriate antibiotic use in children reversed trends in erythromycin resistance to Streptococcus pyogenes. | 2015 | Acta Paediatr. | pmid:26058421 |
Dermota U et al. | Survey of community-associated-methicillin-Resistant Staphylococcus aureus in Slovenia: identification of community-associated and livestock-associated clones. | 2015 | Int. J. Med. Microbiol. | pmid:26055648 |
Drouet M et al. | Endothelial Cell Toxicity of Vancomycin Infusion Combined with Other Antibiotics. | 2015 | Antimicrob. Agents Chemother. | pmid:26055373 |
Reeves M et al. | Acute colonic pseudo-obstruction in pregnancy. | 2015 | ANZ J Surg | pmid:26044983 |
Vlakh EG et al. | Preparation and characterization of macroporous monoliths imprinted with erythromycin. | 2015 | J Sep Sci | pmid:26033867 |
Wang L et al. | Changes in diversity of cultured bacteria resistant to erythromycin and tetracycline in swine manure during simulated composting and lagoon storage. | 2015 | Lett. Appl. Microbiol. | pmid:26031793 |
Wang Z et al. | MicroRNA 21 is a homeostatic regulator of macrophage polarization and prevents prostaglandin E2-mediated M2 generation. | 2015 | PLoS ONE | pmid:25706647 |
Yoon IA et al. | Clinical significance of serotype V among infants with invasive group B streptococcal infections in South Korea. | 2015 | Int. J. Infect. Dis. | pmid:26026823 |
Gherardi G et al. | Decline in macrolide resistance rates among Streptococcus pyogenes causing pharyngitis in children isolated in Italy. | 2015 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:26024763 |
Reveiz L and Cardona AF | Antibiotics for acute laryngitis in adults. | 2015 | Cochrane Database Syst Rev | pmid:26002823 |
Pesola AK et al. | Clindamycin resistant emm33 Streptococcus pyogenes emerged among invasive infections in Helsinki metropolitan area, Finland, 2012 to 2013. | 2015 | Euro Surveill. | pmid:25990232 |
Sun XJ et al. | Combination of erythromycin and dexamethasone improves corticosteroid sensitivity induced by CSE through inhibiting PI3K-δ/Akt pathway and increasing GR expression. | 2015 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:25957293 |
Guo MT et al. | Insights into the amplification of bacterial resistance to erythromycin in activated sludge. | 2015 | Chemosphere | pmid:25957255 |
Kasai A et al. | Prevalence and molecular analysis of macrolide-resistant Moraxella catarrhalis clinical isolates in Japan, following emergence of the highly macrolide-resistant strain NSH1 in 2011. | 2015 | J. Med. Microbiol. | pmid:25934551 |
Hao H et al. | Identification of Campylobacter jejuni and determination of point mutations associated with macrolide resistance using a multiplex TaqMan MGB real-time PCR. | 2015 | J. Appl. Microbiol. | pmid:25766481 |
Nonaka L et al. | Novel macrolide-resistance genes, mef(C) and mph(G), carried by plasmids from Vibrio and Photobacterium isolated from sediment and seawater of a coastal aquaculture site. | 2015 | Lett. Appl. Microbiol. | pmid:25765542 |
Mills RO et al. | Epidemiology of pneumococcal carriage in children under five years of age in Accra, Ghana. | 2015 | Infect Dis (Lond) | pmid:25761718 |
Hersch M et al. | Prokinetic drugs for gastric emptying in critically ill ventilated patients: Analysis through breath testing. | 2015 | J Crit Care | pmid:25746849 |
Lee S et al. | Functional analysis of Vibrio vulnificus RND efflux pumps homologous to Vibrio cholerae VexAB and VexCD, and to Escherichia coli AcrAB. | 2015 | J. Microbiol. | pmid:25740377 |
Lysnyansky I et al. | Decreased Susceptibility to Macrolide-Lincosamide in Mycoplasma synoviae Is Associated with Mutations in 23S Ribosomal RNA. | 2015 | Microb. Drug Resist. | pmid:25734368 |
Abreu AC et al. | Combinatorial Activity of Flavonoids with Antibiotics Against Drug-Resistant Staphylococcus aureus. | 2015 | Microb. Drug Resist. | pmid:25734256 |
Ou H et al. | Selective removal of erythromycin by magnetic imprinted polymers synthesized from chitosan-stabilized Pickering emulsion. | 2015 | J. Hazard. Mater. | pmid:25704432 |
Ikebe T et al. | Increased prevalence of group A streptococcus isolates in streptococcal toxic shock syndrome cases in Japan from 2010 to 2012. | 2015 | Epidemiol. Infect. | pmid:25703404 |
Li Y et al. | Where macrolide resistance is prevalent. | 2015 | APMIS | pmid:25703275 |
Chemler JA et al. | Evolution of Efficient Modular Polyketide Synthases by Homologous Recombination. | 2015 | J. Am. Chem. Soc. | pmid:26230368 |
Choi JH et al. | Distribution of emm types among group A Streptococcus isolates from children in Korea. | 2015 | Diagn. Microbiol. Infect. Dis. | pmid:25700867 |
Luo H et al. | Identification of ribosomal RNA methyltransferase gene ermF in Riemerella anatipestifer. | 2015 | Avian Pathol. | pmid:25690020 |
Sessa R et al. | Effects of Mentha suaveolens essential oil on Chlamydia trachomatis. | 2015 | Biomed Res Int | pmid:25685793 |
Shi JG et al. | Predicting drug-drug interactions involving multiple mechanisms using physiologically based pharmacokinetic modeling: a case study with ruxolitinib. | 2015 | Clin. Pharmacol. Ther. | pmid:25670523 |
Cetecioglu Z et al. | Acute effect of erythromycin on metabolic transformations of volatile fatty acid mixture under anaerobic conditions. | 2015 | Chemosphere | pmid:25542637 |
Novak I and KovaÄ B | Electronic structure of antibiotic erythromycin. | 2015 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:25528514 |
Ansari NN et al. | A randomized clinical trial comparing pulsed ultrasound and erythromycin phonophoresis in the treatment of patients with chronic rhinosinusitis. | 2015 | Physiother Theory Pract | pmid:25495769 |
Nagelreiter C et al. | Dilution of semi-solid creams: influence of various production parameters on rheological properties and skin penetration. | 2015 | Int J Pharm | pmid:25475015 |
Harmer CJ et al. | A type 2 A/C2 plasmid carrying the aacC4 apramycin resistance gene and the erm(42) erythromycin resistance gene recovered from two Salmonella enterica serovars. | 2015 | J. Antimicrob. Chemother. | pmid:25468903 |
Wan J et al. | Effect of erythromycin exposure on the growth, antioxidant system and photosynthesis of Microcystis flos-aquae. | 2015 | J. Hazard. Mater. | pmid:25464321 |
Zhou Z et al. | Macrolide-resistant Mycoplasma pneumoniae in adults in Zhejiang, China. | 2015 | Antimicrob. Agents Chemother. | pmid:25451048 |
Hur J et al. | Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis. | 2015 | Chem. Res. Toxicol. | pmid:25811541 |
Haxel BR et al. | Controlled trial for long-term low-dose erythromycin after sinus surgery for chronic rhinosinusitis. | 2015 | Laryngoscope | pmid:25425539 |
Berg C et al. | Significance of archaeal nitrification in hypoxic waters of the Baltic Sea. | 2015 | ISME J | pmid:25423026 |
Galvidis I et al. | Group determination of 14-membered macrolide antibiotics and azithromycin using antibodies against common epitopes. | 2015 | Anal. Biochem. | pmid:25256165 |
Siekmeier R et al. | Inhalation of macrolides: a novel approach to treatment of pulmonary infections. | 2015 | Adv. Exp. Med. Biol. | pmid:25252902 |
Chen Y et al. | The glucose RQ-feedback control leading to improved erythromycin production by a recombinant strain Saccharopolyspora erythraea ZL1004 and its scale-up to 372-m(3) fermenter. | 2015 | Bioprocess Biosyst Eng | pmid:25042891 |
Llorca M et al. | Identification of new transformation products during enzymatic treatment of tetracycline and erythromycin antibiotics at laboratory scale by an on-line turbulent flow liquid-chromatography coupled to a high resolution mass spectrometer LTQ-Orbitrap. | 2015 | Chemosphere | pmid:24972175 |
Mazur CS et al. | P-glycoprotein inhibition by the agricultural pesticide propiconazole and its hydroxylated metabolites: Implications for pesticide-drug interactions. | 2015 | Toxicol. Lett. | pmid:25268938 |
Song LY et al. | Exploring Synergy between Classic Mutagens and Antibiotics To Examine Mechanisms of Synergy and Antibiotic Action. | 2015 | Antimicrob. Agents Chemother. | pmid:26711761 |
Cochrane SA et al. | Synthesis of Tridecaptin-Antibiotic Conjugates with in Vivo Activity against Gram-Negative Bacteria. | 2015 | J. Med. Chem. | pmid:26636619 |
Liang Z et al. | Structural Correspondence of the Oriented Attachment Growth Mechanism of Crystals of the Pharmaceutical Dirithromycin. | 2015 | Langmuir | pmid:26632998 |
Wilson DW et al. | Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum. | 2015 | BMC Biol. | pmid:26187647 |
Aydın S et al. | Inhibitory effect of erythromycin, tetracycline and sulfamethoxazole antibiotics on anaerobic treatment of a pharmaceutical wastewater. | 2015 | Water Sci. Technol. | pmid:26038926 |
Bérard A et al. | Use of macrolides during pregnancy and the risk of birth defects: a population-based study. | 2015 | Pharmacoepidemiol Drug Saf | pmid:26513406 |
Fedashchin A et al. | Random transposon mutagenesis of the Saccharopolyspora erythraea genome reveals additional genes influencing erythromycin biosynthesis. | 2015 | FEMS Microbiol. Lett. | pmid:26468041 |
Lu H et al. | High frequency of the 23S rRNA A2058G mutation of Treponema pallidum in Shanghai is associated with a current strategy for the treatment of syphilis. | 2015 | Emerg Microbes Infect | pmid:26038763 |
Yi X et al. | Improved detection of multiple environmental antibiotics through an optimized sample extraction strategy in liquid chromatography-mass spectrometry analysis. | 2015 | Anal Bioanal Chem | pmid:26449847 |
Ayazi P et al. | Tick-borne Relapsing Fever in Children in the North-west of Iran, Qazvin. | 2015 | Prague Med Rep | pmid:26445390 |
Yamaguchi M et al. | Calcitonin Receptor Signaling Inhibits Muscle Stem Cells from Escaping the Quiescent State and the Niche. | 2015 | Cell Rep | pmid:26440893 |
Chazan B et al. | Susceptibility of Group A Streptococcus to Antimicrobial Agents in Northern Israel: A Surveillance Study. | 2015 | Microb. Drug Resist. | pmid:26430943 |
Kojima C et al. | Distribution of Antimicrobial Resistance in Campylobacter Strains Isolated from Poultry at a Slaughterhouse and Supermarkets in Japan. | 2015 | Biocontrol Sci | pmid:26412697 |
Hoffmann K et al. | Prevalence and resistance patterns of commensal S. aureus in community-dwelling GP patients and socio-demographic associations. A cross-sectional study in the framework of the APRES-project in Austria. | 2015 | BMC Infect. Dis. | pmid:25981559 |
Å mitran A et al. | Effects of penicillin and erythromycin on adherence of invasive and noninvasive isolates of Streptococcus pyogenes to laminin. | 2015 | Mem. Inst. Oswaldo Cruz | pmid:26270594 |
Wang YL et al. | Development of a Method for the Analysis of Multiclass Antibiotic Residues in Milk Using QuEChERS and Liquid Chromatography-Tandem Mass Spectrometry. | 2015 | Foodborne Pathog. Dis. | pmid:26258263 |
Prohl A et al. | Enrofloxacin and macrolides alone or in combination with rifampicin as antimicrobial treatment in a bovine model of acute Chlamydia psittaci infection. | 2015 | PLoS ONE | pmid:25768665 |
Enayati M et al. | Virulence and antimicrobial resistance of Enterococcus faecium isolated from water samples. | 2015 | Lett. Appl. Microbiol. | pmid:26249819 |
Peyre L et al. | High-content screening imaging and real-time cellular impedance monitoring for the assessment of chemical's bio-activation with regards hepatotoxicity. | 2015 | Toxicol In Vitro | pmid:26239606 |
Banik A et al. | Inducible and constitutive clindamycin resistance in Staphylococcus aureus in a northeastern Indian tertiary care hospital. | 2015 | J Infect Dev Ctries | pmid:26230122 |
Wang Z et al. | Direct Detection of Erythromycin-Resistant Bordetella pertussis in Clinical Specimens by PCR. | 2015 | J. Clin. Microbiol. | pmid:26224847 |
Olivieri R et al. | Evolution of macrolide resistance in Streptococcus pyogenes over 14 years in an area of central Italy. | 2015 | J. Med. Microbiol. | pmid:26224594 |
Mazumdar G and Shome K | Stevens-Johnson syndrome following use of metronidazole in a dental patient. | 2014 Jan-Feb | Indian J Pharmacol | pmid:24550598 |
Cetecioglu Z | Aerobic inhibition assessment for anaerobic treatment effluent of antibiotic production wastewater. | 2014 | Environ Sci Pollut Res Int | pmid:24146324 |
Gustafsson F et al. | A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans. | 2014 | Toxicol. Sci. | pmid:24085192 |
Pierson RC et al. | A retrospective comparison of antibiotic regimens for preterm premature rupture of membranes. | 2014 | Obstet Gynecol | pmid:25162251 |
Källén B and Danielsson BR | Fetal safety of erythromycin. An update of Swedish data. | 2014 | Eur. J. Clin. Pharmacol. | pmid:24352632 |
Rozov-Ung I et al. | Detection of drug effects on gastric emptying and contractility using a wireless motility capsule. | 2014 | BMC Gastroenterol | pmid:24383478 |
ŽemliÄková H et al. | [Resistance monitoring working group: resistance to erythromycin, ciprofloxacin, and tetracycline in human isolates of Campylobacter spp. in the Czech Republic tested by the EUCAST standard method]. | 2014 | Epidemiol Mikrobiol Imunol | pmid:25412481 |
Arêas GP et al. | Antimicrobial susceptibility patterns, emm type distribution and genetic diversity of Streptococcus pyogenes recovered in Brazil. | 2014 | Mem. Inst. Oswaldo Cruz | pmid:25410998 |
Wang J et al. | [Drug susceptibility and homologous analysis on Corynebacterium striatum strains isolated from inpatients]. | 2014 | Zhonghua Yi Xue Za Zhi | pmid:25410920 |
Wu H et al. | Dissecting and engineering of the TetR family regulator SACE_7301 for enhanced erythromycin production in Saccharopolyspora erythraea. | 2014 | Microb. Cell Fact. | pmid:25391994 |
Johnson SR et al. | In Vitro selection of Neisseria gonorrhoeae mutants with elevated MIC values and increased resistance to cephalosporins. | 2014 | Antimicrob. Agents Chemother. | pmid:25199775 |
Kara M et al. | Expression changes of antioxidant, apoptotic, anti-apoptotic genes and miR-15b-34a-21-98 in over tissue by using erythromycin, quinacrine and tetracycline in non-surgical sterilization. | 2014 | Mol. Biol. Rep. | pmid:25195052 |
Shera IA et al. | Unusual case of Hashimoto's encephalopathy and pseudo-obstruction in a patient with undiagnosed hypothyroidism: a case report. | 2014 | J Med Case Rep | pmid:25194644 |
Usui M et al. | Selection of macrolide-resistant Campylobacter in pigs treated with macrolides. | 2014 | Vet. Rec. | pmid:25163817 |
Komiya K et al. | Long-term, low-dose erythromycin monotherapy for Mycobacterium avium complex lung disease: a propensity score analysis. | 2014 | Int. J. Antimicrob. Agents | pmid:24948577 |
Dutra VG et al. | Streptococcus agalactiae in Brazil: serotype distribution, virulence determinants and antimicrobial susceptibility. | 2014 | BMC Infect. Dis. | pmid:24919844 |
Arana DM et al. | First clinical isolate in Europe of clindamycin-resistant group B Streptococcus mediated by the lnu(B) gene. | 2014 | Rev Esp Quimioter | pmid:24940891 |
Crumb WJ | Allosteric effects of erythromycin pretreatment on thioridazine block of hERG potassium channels. | 2014 | Br. J. Pharmacol. | pmid:24417241 |
Luan R et al. | [Erythromycin for improving enteral nutrition tolerance in adult critical patients: a systematic review and meta-analysis]. | 2014 | Zhonghua Wei Zhong Bing Ji Jiu Yi Xue | pmid:24912643 |
Liu J et al. | Tissue distribution, bioconcentration, metabolism, and effects of erythromycin in crucian carp (Carassius auratus). | 2014 | Sci. Total Environ. | pmid:24911771 |
Dechert-Schmitt AM et al. | Polyketide construction via hydrohydroxyalkylation and related alcohol C-H functionalizations: reinventing the chemistry of carbonyl addition. | 2014 | Nat Prod Rep | pmid:24514754 |
Janoir C et al. | Clonal expansion of the macrolide resistant ST386 within pneumococcal serotype 6C in France. | 2014 | PLoS ONE | pmid:24603763 |
Melnik BC | The P450 system and mTORC1 signalling in acne. | 2014 | Exp. Dermatol. | pmid:24588627 |
Xiao C et al. | Effect of magnesium sulfate and nifedipine on the risk of developing pulmonary edema in preterm births. | 2014 | J Perinat Med | pmid:24566358 |
Montes M et al. | What causes decreased erythromycin resistance in Streptococcus pyogenes? Dynamics of four clones in a southern European region from 2005 to 2012. | 2014 | J. Antimicrob. Chemother. | pmid:24562616 |
Csikó G et al. | Effects of dietary sodium butyrate on hepatic biotransformation and pharmacokinetics of erythromycin in chickens. | 2014 | J. Vet. Pharmacol. Ther. | pmid:24628435 |
Aydin S et al. | Performance of anaerobic sequencing batch reactor in the treatment of pharmaceutical wastewater containing erythromycin and sulfamethoxazole mixture. | 2014 | Water Sci. Technol. | pmid:25429450 |