| MeSH term | MeSH ID | Detail |
|---|---|---|
| Epidural Abscess | D020802 | 1 associated lipids |
| Skin Diseases, Vascular | D017445 | 1 associated lipids |
erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
|---|
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Novikova SI et al. | Introduction of a mini-gene encoding a five-amino acid peptide confers erythromycin resistance on Bacillus subtilis and provides temporary erythromycin protection in Proteus mirabilis. | 2000 | FEMS Microbiol. Lett. | pmid:10620668 |
| Chieppa DM et al. | Effects of erythromycin on human colonic circular muscle in idiopathic chronic constipation. | 2000 | Eur. J. Clin. Invest. | pmid:10620004 |
| National guideline for the management of chancroid. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases). | 1999 | Sex Transm Infect | pmid:10616383 | |
| National guideline for the management of lymphogranuloma venereum. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases). | 1999 | Sex Transm Infect | pmid:10616382 | |
| National guideline for the management of early syphilis. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases). | 1999 | Sex Transm Infect | pmid:10616379 | |
| National guideline for the management of non-gonococcal urethritis. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases) | 1999 | Sex Transm Infect | pmid:10616373 | |
| National guideline for the management of Chlamydia trachomatis genital tract infection. Clinical Effectiveness Group (Association of Genitourinary Medicine and the Medical Society for the Study of Venereal Diseases). | 1999 | Sex Transm Infect | pmid:10616372 | |
| Urmösi J | [Thrombophlebitis of the sinus cavernosus]. | 1975 | Stomatol DDR | pmid:1061410 |
| Czeizel AE et al. | A population-based case-control teratologic study of oral erythromycin treatment during pregnancy. | 1999 Nov-Dec | Reprod. Toxicol. | pmid:10613401 |
| Altomare G et al. | Treatment of bullous pemphigoid with erythromycin: a reappraisal. | 1999 Oct-Nov | Eur J Dermatol | pmid:10610238 |
| Honein MA et al. | Infantile hypertrophic pyloric stenosis after pertussis prophylaxis with erythromcyin: a case review and cohort study. | 1999 Dec 18-25 | Lancet | pmid:10609814 |
| Wang JS et al. | Fluvoxamine is a more potent inhibitor of lidocaine metabolism than ketoconazole and erythromycin in vitro. | 1999 | Pharmacol. Toxicol. | pmid:10608481 |
| Sato Y et al. | Adjuvant effect of a 14-member macrolide antibiotic on DNA vaccine. | 1999 | Cell. Immunol. | pmid:10607432 |
| Ianaro A et al. | Anti-inflammatory activity of macrolide antibiotics. | 2000 | J. Pharmacol. Exp. Ther. | pmid:10604943 |
| Ku YY et al. | Synthesis and antibacterial activities of novel 12-O-methylerythromycin A derivatives. | 1999 | J. Antibiot. | pmid:10604761 |
| Marre R and Trautmann M | [Community-acquired respiratory tract infections. Current data on the efficacy of various classes of antibiotics and antibiotic resistance of the main prevalent bacteria species]. | 1999 | Med. Klin. (Munich) | pmid:10603732 |
| Fluhr JW et al. | In-vitro and in-vivo efficacy of zinc acetate against propionibacteria alone and in combination with erythromycin. | 1999 | Zentralbl. Bakteriol. | pmid:10603662 |
| Esposito S et al. | In vitro activity of moxifloxacin compared to other fluoroquinolones against different erythromycin-resistant phenotypes of group A beta-hemolytic streptococcus. | 2000 Jan-Feb | Chemotherapy | pmid:10601794 |
| Polk RE et al. | Pharmacokinetic interaction between ketoconazole and amprenavir after single doses in healthy men. | 1999 | Pharmacotherapy | pmid:10600086 |
| Sugiyama Y et al. | Effects of long-term administration of erythromycin on cytokine production in rat alveolar macrophages. | 1999 | Eur. Respir. J. | pmid:10596699 |
| Portillo A et al. | Macrolide resistance phenotypes and mechanisms of resistance in Streptococcus pyogenes in La Rioja, Spain. | 1999 | Int. J. Antimicrob. Agents | pmid:10595574 |
| Doumith M et al. | Interspecies complementation in Saccharopolyspora erythraea : elucidation of the function of oleP1, oleG1 and oleG2 from the oleandomycin biosynthetic gene cluster of Streptomyces antibioticus and generation of new erythromycin derivatives. | 1999 | Mol. Microbiol. | pmid:10594828 |
| Damkier P et al. | Effect of diclofenac, disulfiram, itraconazole, grapefruit juice and erythromycin on the pharmacokinetics of quinidine. | 1999 | Br J Clin Pharmacol | pmid:10594487 |
| Brixius B et al. | [Ventricular tachycardia after erythromycin administration in a newborn with congenital AV-block]. | 1999 Nov-Dec | Klin Padiatr | pmid:10592929 |
| Debbia EA | [Antibiotic resistance: an always present problem]. | 1999 | Recenti Prog Med | pmid:10592734 |
| Glass D et al. | A placebo-controlled clinical trial to compare a gel containing a combination of isotretinoin (0.05%) and erythromycin (2%) with gels containing isotretinoin (0.05%) or erythromycin (2%) alone in the topical treatment of acne vulgaris. | 1999 | Dermatology (Basel) | pmid:10592405 |
| Varaldo PE et al. | Nationwide survey in Italy of treatment of Streptococcus pyogenes pharyngitis in children: influence of macrolide resistance on clinical and microbiological outcomes. Artemis-Italy Study Group. | 1999 | Clin. Infect. Dis. | pmid:10589905 |
| Panagea S et al. | Should clindamycin be used as treatment of patients with infections caused by erythromycin-resistant staphylococci? | 1999 | J. Antimicrob. Chemother. | pmid:10588329 |
| Wilson R et al. | Five day moxifloxacin therapy compared with 7 day clarithromycin therapy for the treatment of acute exacerbations of chronic bronchitis. | 1999 | J. Antimicrob. Chemother. | pmid:10588312 |
| Marchese A et al. | Macrolide resistance mechanisms and expression of phenotypes among Streptococcus pneumoniae circulating in Italy. | 1999 | J. Antimicrob. Chemother. | pmid:10588306 |
| Carsenti-Etesse H et al. | Gradient plate method to induce Streptococcus pyogenes resistance. | 1999 | J. Antimicrob. Chemother. | pmid:10588303 |
| Durak H et al. | Tc-99m erythromycin lactobionate inhalation scintigraphy in parenchymal lung diseases. | 1999 | Nucl. Med. Biol. | pmid:10587109 |
| McCrea J et al. | Concurrent administration of the erythromycin breath test (EBT) and oral midazolam as in vivo probes for CYP3A activity. | 1999 | J Clin Pharmacol | pmid:10586386 |
| Zarazaga M et al. | In vitro activities of ketolide HMR3647, macrolides, and other antibiotics against Lactobacillus, Leuconostoc, and Pediococcus isolates. | 1999 | Antimicrob. Agents Chemother. | pmid:10582908 |
| Klausner MA | Astemizole use with erythromycin. | 1999 | Ann. Allergy Asthma Immunol. | pmid:10582723 |
| Kudo S | [Diffuse panbronchiolitis and erythromycin therapy]. | 1999 | Nippon Naika Gakkai Zasshi | pmid:10581765 |
| Brown MS et al. | Production of 6-deoxy-13-cyclopropyl-erythromycin B by Saccharopolyspora erythraea NRRL 18643. | 1999 | J. Antibiot. | pmid:10580387 |
| Peng L and Nimni ME | Delivery of erythromycin to subcutaneous tissues in rats by means of a trans-phase delivery system. | 1999 | J. Pharm. Pharmacol. | pmid:10579684 |
| Clarke AE et al. | Interaction of bile with erythromycin Lactobionate in vitro. | 1975 | Aust N Z J Med | pmid:1057910 |
| Kondo T et al. | Application of liquid chromatography-turbo ion spray tandem mass spectrometry for quantitative analysis of a potent motilin receptor agonist, EM574, and its metabolites in human plasma. | 1999 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:10574195 |
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| Melo-Cristino J and Fernandes ML | Streptococcus pyogenes isolated in Portugal: macrolide resistance phenotypes and correlation with T types. Portuguese Surveillance Group for the Study of Respiratory Pathogens. | 1999 | Microb. Drug Resist. | pmid:10566873 |
| Menezes CM et al. | In vitro evaluation of erythromycin in chloroquine resistant brazilian P. falciparum freshly isolates: modulating effect and antimalarial activity evidence. | 1999 Jul-Aug | Rev. Inst. Med. Trop. Sao Paulo | pmid:10564920 |
| Matsuoka M et al. | Cloning and sequences of inducible and constitutive macrolide resistance genes in Staphylococcus aureus that correspond to an ABC transporter. | 1999 | FEMS Microbiol. Lett. | pmid:10564793 |
| Morel P et al. | Clinical efficacy and safety of a topical combination of retinaldehyde 0.1% with erythromycin 4% in acne vulgaris. | 1999 | Clin. Exp. Dermatol. | pmid:10564319 |
| Bauer JF et al. | Role of an isomorphic desolvate in dissolution failures of an erythromycin tablet formulation. | 1999 | J Pharm Sci | pmid:10564073 |
| Denis A et al. | Synthesis and antibacterial activity of HMR 3647 a new ketolide highly potent against erythromycin-resistant and susceptible pathogens. | 1999 | Bioorg. Med. Chem. Lett. | pmid:10560728 |
| Reeves AR et al. | Transcriptional organization of the erythromycin biosynthetic gene cluster of Saccharopolyspora erythraea. | 1999 | J. Bacteriol. | pmid:10559177 |
| Malonza IM et al. | A randomized, double-blind, placebo-controlled trial of single-dose ciprofloxacin versus erythromycin for the treatment of chancroid in Nairobi, Kenya. | 1999 | J. Infect. Dis. | pmid:10558945 |
| Erythromycin and gastroparesis? Off-licence use: uncertain efficacy for a poorly defined disorder. | 1999 | Prescrire Int | pmid:10557568 |