MeSH term | MeSH ID | Detail |
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Vagus Nerve Injuries | D061223 | 1 associated lipids |
Drug-Related Side Effects and Adverse Reactions | D064420 | 3 associated lipids |
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Oo C and Shah B | Does erythromycin have anti-inflammatory effects independent of its antimicrobial action? | 2012 | J Clin Pharmacol | pmid:21868717 |
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GarcÃa-Pérez ME et al. | Picea mariana bark: a new source of trans-resveratrol and other bioactive polyphenols. | 2012 | Food Chem | pmid:22953840 |
Martins ER et al. | Dominance of serotype Ia among group B Streptococci causing invasive infections in nonpregnant adults in Portugal. | 2012 | J. Clin. Microbiol. | pmid:22219307 |
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Ullrich K et al. | Neuroretinitis following bull ant sting. | 2012 | BMJ Case Rep | pmid:22865803 |
Pinto A et al. | 6-Deoxyerythronolide B synthase thioesterase-catalyzed macrocyclization is highly stereoselective. | 2012 | Org. Lett. | pmid:22519860 |
Yuzawa S et al. | Role of a conserved arginine residue in linkers between the ketosynthase and acyltransferase domains of multimodular polyketide synthases. | 2012 | Biochemistry | pmid:22509729 |
Wang Y et al. | The preferred conformation of erythro- and threo-1,2-difluorocyclododecanes. | 2012 | Beilstein J Org Chem | pmid:23019458 |
Shimizu S et al. | Reactivity of lignin with different composition of aromatic syringyl/guaiacyl structures and erythro/threo side chain structures in β-O-4 type during alkaline delignification: as a basis for the different degradability of hardwood and softwood lignin. | 2012 | J. Agric. Food Chem. | pmid:22694300 |
Karlgren M et al. | Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. | 2012 | J. Med. Chem. | pmid:22541068 |
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Deane AM et al. | Randomized double-blind crossover study to determine the effects of erythromycin on small intestinal nutrient absorption and transit in the critically ill. | 2012 | Am. J. Clin. Nutr. | pmid:22572649 |
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Henningsen E and Bygum A | Budesonide-induced periorificial dermatitis presenting as chalazion and blepharitis. | 2011 Sep-Oct | Pediatr Dermatol | pmid:21895758 |
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Zhang W et al. | Construction and expression of food-grade β-galactosidase gene in Lactococcus Lactis. | 2011 | Curr. Microbiol. | pmid:20924584 |
Hewer RC et al. | PKA and Epac synergistically inhibit smooth muscle cell proliferation. | 2011 | J. Mol. Cell. Cardiol. | pmid:20971121 |
Fessler AT et al. | Novel apramycin resistance gene apmA in bovine and porcine methicillin-resistant Staphylococcus aureus ST398 isolates. | 2011 | Antimicrob. Agents Chemother. | pmid:20876371 |
Cai XJ et al. | [Protective effects of erythromycin on human bronchial epithelial cells impaired by interleukin-4]. | 2011 | Zhonghua Yi Xue Za Zhi | pmid:22094097 |
Otsu K et al. | Effects of a novel nonantibiotic macrolide, EM900, on cytokine and mucin gene expression in a human airway epithelial cell line. | 2011 | Pharmacology | pmid:22116077 |
Nakashima R et al. | Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket. | 2011 | Nature | pmid:22121023 |
Abarzúa F et al. | [Streptococcus agalactiae increase in resistance to erythromycin and clindamycin in vaginal-anal colonization in third quarter of pregnancy in one decade of universal screening]. | 2011 | Rev Chilena Infectol | pmid:22052397 |
Song W et al. | Cyclodextrin-erythromycin complexes as a drug delivery device for orthopedic application. | 2011 | Int J Nanomedicine | pmid:22228990 |
Hiller NL et al. | Differences in genotype and virulence among four multidrug-resistant Streptococcus pneumoniae isolates belonging to the PMEN1 clone. | 2011 | PLoS ONE | pmid:22205975 |
Tachecà I et al. | Electrogastrography in experimental pigs: the influence of gastrointestinal injury induced by dextran sodium sulphate on porcine gastric erythromycin-stimulated myoelectric activity. | 2011 | Neuro Endocrinol. Lett. | pmid:22167215 |
Nielsen EI et al. | Predicting in vitro antibacterial efficacy across experimental designs with a semimechanistic pharmacokinetic-pharmacodynamic model. | 2011 | Antimicrob. Agents Chemother. | pmid:21282424 |
Belousoff MJ et al. | Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit. | 2011 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21282615 |
Spigaglia P et al. | Surface layer protein A variant of Clostridium difficile PCR-ribotype 027. | 2011 | Emerging Infect. Dis. | pmid:21291621 |
Huppertz A et al. | Evaluation of possible drug-drug interaction between gadoxetic acid and erythromycin as an inhibitor of organic anion transporting peptides (OATP). | 2011 | J Magn Reson Imaging | pmid:21274983 |
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Zhang Q et al. | Knocking out of tailoring genes eryK and eryG in an industrial erythromycin-producing strain of Saccharopolyspora erythraea leading to overproduction of erythromycin B, C and D at different conversion ratios. | 2011 | Lett. Appl. Microbiol. | pmid:21175699 |
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Ma S et al. | Synthesis and antibacterial evaluation of novel clarithromycin derivatives with C-4″ elongated arylalkyl groups against macrolide-resistant strains. | 2011 | Eur J Med Chem | pmid:21159410 |
Mak PJ et al. | Defining CYP3A4 structural responses to substrate binding. Raman spectroscopic studies of a nanodisc-incorporated mammalian cytochrome P450. | 2011 | J. Am. Chem. Soc. | pmid:21207936 |
Chen Y et al. | Determination of time-dependent inactivation of CYP3A4 in cryopreserved human hepatocytes and assessment of human drug-drug interactions. | 2011 | Drug Metab. Dispos. | pmid:21835977 |
Ahmetagic A et al. | Plasmid encoded antibiotics inhibit protozoan predation of Escherichia coli K12. | 2011 | Plasmid | pmid:21839110 |
Zhou L et al. | Serotype distribution and antibiotic resistance of 140 pneumococcal isolates from pediatric patients with upper respiratory infections in Beijing, 2010. | 2011 | Vaccine | pmid:21839135 |
Wu J et al. | Toward improvement of erythromycin A production in an industrial Saccharopolyspora erythraea strain via facilitation of genetic manipulation with an artificial attB site for specific recombination. | 2011 | Appl. Environ. Microbiol. | pmid:21841022 |
Raynes Greenow CH et al. | Antibiotics for ureaplasma in the vagina in pregnancy. | 2011 | Cochrane Database Syst Rev | pmid:21901685 |
Wunder DB et al. | Sorption of antibiotics to biofilm. | 2011 | Water Res. | pmid:21334040 |
Senthilkumaran S and Subramanian PT | Prolonged sedation related to erythromycin and midazolam interaction: a word of caution. | 2011 | Indian Pediatr | pmid:22711153 |
Sonnevend à et al. | Lack of correlation between the 257C-to-T mutation in the gyrA gene and clinical severity of Campylobacter jejuni infection in a region of high incidence of ciprofloxacin resistance. | 2011 | Scand. J. Infect. Dis. | pmid:21905953 |
Sigaroudinia MO and Quayle AR | Oral erythromycin relieves dysphagia in a patient with known oesophageal hypomotility disorder who has had a Nissen's fundoplication. | 2011 | Surgeon | pmid:21550524 |
Szary NM et al. | Erythromycin prior to endoscopy in acute upper gastrointestinal bleeding: a meta-analysis. | 2011 | Scand. J. Gastroenterol. | pmid:21561232 |
Wei Z and Wang J | Detection of antibiotic residues in bovine milk by a voltammetric electronic tongue system. | 2011 | Anal. Chim. Acta | pmid:21565301 |
Ren W and Markel DC | Emerging ideas: can erythromycin reduce the risk of aseptic loosening? | 2011 | Clin. Orthop. Relat. Res. | pmid:21584820 |
Torra S et al. | Meal size can be decreased in obese subjects through pharmacological acceleration of gastric emptying (The OBERYTH trial). | 2011 | Int J Obes (Lond) | pmid:20938444 |
Li MJ et al. | High electrochemiluminescence of a new water-soluble iridium(III) complex for determination of antibiotics. | 2011 | Analyst | pmid:20944848 |
Andini N and Nash KA | Expression of tmRNA in mycobacteria is increased by antimicrobial agents that target the ribosome. | 2011 | FEMS Microbiol. Lett. | pmid:21718348 |
Li AP and Doshi U | Higher throughput human hepatocyte assays for the evaluation of time-dependent inhibition of CYP3A4. | 2011 | Drug Metab Lett | pmid:21722087 |
Imperi M et al. | Invasive neonatal GBS infections from an area-based surveillance study in Italy. | 2011 | Clin. Microbiol. Infect. | pmid:21722258 |
Wan G et al. | Cyclic AMP signalling through PKA but not Epac is essential for neurturin-induced biphasic ERK1/2 activation and neurite outgrowths through GFRα2 isoforms. | 2011 | Cell. Signal. | pmid:21723942 |
Kalmokoff M et al. | Continuous feeding of antimicrobial growth promoters to commercial swine during the growing/finishing phase does not modify faecal community erythromycin resistance or community structure. | 2011 | J. Appl. Microbiol. | pmid:21395944 |
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Chen I et al. | Emergence of erythromycin- and clindamycin-resistant Streptococcus pyogenes emm 90 strains in Hawaii. | 2011 | J. Clin. Microbiol. | pmid:21068284 |
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Mikura S et al. | Erythromycin prevents the pulmonary inflammation induced by exposure to cigarette smoke. | 2011 | Transl Res | pmid:21708354 |
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Gupta R et al. | A 14-year-old with rectal bleeding and abdominal pain. | 2011 | J. Pediatr. Gastroenterol. Nutr. | pmid:21970991 |
Pignatello R et al. | Amphiphilic erythromycin-lipoamino acid ion pairs: characterization and in vitro microbiological evaluation. | 2011 | AAPS PharmSciTech | pmid:21479751 |
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Franke RM et al. | Effect of ABCC2 (MRP2) transport function on erythromycin metabolism. | 2011 | Clin. Pharmacol. Ther. | pmid:21451505 |
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Zhang Z et al. | Novel molecularly imprinted polymers based on multi-walled carbon nanotubes with binary functional monomer for the solid-phase extraction of erythromycin from chicken muscle. | 2011 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:21498135 |
Del Grosso M et al. | Genetic resistance elements carrying mef subclasses other than mef(A) in Streptococcus pyogenes. | 2011 | Antimicrob. Agents Chemother. | pmid:21502613 |
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Wei Z et al. | [Treatment of low-dose erythromycin and sinus displacement on sinusitis in patients with nasopharyngeal carcinoma after radiotherapy]. | 2011 | Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi | pmid:22260078 |
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