MeSH term | MeSH ID | Detail |
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Vagus Nerve Injuries | D061223 | 1 associated lipids |
Drug-Related Side Effects and Adverse Reactions | D064420 | 3 associated lipids |
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Arisoy ES et al. | Corynebacterium xerosis ventriculoperitoneal shunt infection in an infant: report of a case and review of the literature. | 1993 | Pediatr. Infect. Dis. J. | pmid:8345988 |
Donadio S et al. | An erythromycin analog produced by reprogramming of polyketide synthesis. | 1993 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8346223 |
Rockwood RP and Embardo LS | Theophylline, ciprofloxacin, erythromycin: a potentially harmful regimen. | 1993 | Ann Pharmacother | pmid:8347920 |
Beck DE and Karulf RE | Laparoscopic-assisted full-thickness endoscopic polypectomy. | 1993 | Dis. Colon Rectum | pmid:8348855 |
Bologna SD et al. | Down-regulation of motilin receptors on rabbit colon myocytes by chronic oral erythromycin. | 1993 | J. Pharmacol. Exp. Ther. | pmid:8355213 |
Pellegrini F et al. | [Boutonneuse fever in childhood: a pathology often underdiagnosed. A report of 2 clinical cases]. | 1993 | Minerva Pediatr. | pmid:8355646 |
Helovuo H et al. | Changes in the prevalence of subgingival enteric rods, staphylococci and yeasts after treatment with penicillin and erythromycin. | 1993 | Oral Microbiol. Immunol. | pmid:8355988 |
Bannam TL and Rood JI | Clostridium perfringens-Escherichia coli shuttle vectors that carry single antibiotic resistance determinants. | 1993 | Plasmid | pmid:8356117 |
Pawlik WW et al. | Microcirculatory and motor effects of endogenous nitric oxide in the rat gut. | 1993 | J. Physiol. Pharmacol. | pmid:8358050 |
Wilmer A et al. | 5-hydroxytryptamine-3 receptors are involved in the initiation of gastric phase-3 motor activity in humans. | 1993 | Gastroenterology | pmid:8359648 |
Karmody CS and Weinstein L | Reversible sensorineural hearing loss with intravenous erythromycin lactobionate. | 1977 Jan-Feb | Ann. Otol. Rhinol. Laryngol. | pmid:835977 |
Watanabe Y et al. | Chemical modification of erythromycins. XII. A facile synthesis of clarithromycin (6-O-methylerythromycin A) via 2'-silylethers of erythromycin A derivatives. | 1993 | J. Antibiot. | pmid:8360112 |
Higa F et al. | Influence of methylprednisolone on the intracellular antimicrobial activity of erythromycin and clindamycin against Legionella pneumophila. | 1993 | J. Antimicrob. Chemother. | pmid:8360127 |
Back NA et al. | Recurrent epidemics caused by a single strain of erythromycin-resistant Staphylococcus aureus. The importance of molecular epidemiology. | 1993 | JAMA | pmid:8360968 |
Ismaeel NA | In vitro susceptibility of Haemophilus ducreyi to several antibiotics. | 1993 | Microbios | pmid:8361391 |
Holmberg RE et al. | Nosocomial Legionella pneumonia in the neonate. | 1993 | Pediatrics | pmid:8361801 |
Darelid J et al. | Erythromycin treatment is beneficial for longstanding Moraxella catarrhalis associated cough in children. | 1993 | Scand. J. Infect. Dis. | pmid:8362228 |
Stenberg K and MÃ¥rdh PA | Treatment of concomitant eye and genital chlamydial infection with erythromycin and roxithromycin. | 1993 | Acta Ophthalmol (Copenh) | pmid:8362632 |
Carson JL et al. | Acute liver disease associated with erythromycins, sulfonamides, and tetracyclines. | 1993 | Ann. Intern. Med. | pmid:8363168 |
Knapp JS et al. | In vitro susceptibilities of isolates of Haemophilus ducreyi from Thailand and the United States to currently recommended and newer agents for treatment of chancroid. | 1993 | Antimicrob. Agents Chemother. | pmid:8363390 |
Sacristán JA et al. | Erythromycin-induced hypoacusis: 11 new cases and literature review. | 1993 Jul-Aug | Ann Pharmacother | pmid:8364281 |
de Champs CL et al. | Selective digestive decontamination by erythromycin-base in a polyvalent intensive care unit. | 1993 | Intensive Care Med | pmid:8366226 |
Bannatyne RM and Randall C | Ecology of 350 isolates of group F Streptococcus. | 1977 | Am. J. Clin. Pathol. | pmid:836625 |
Colman G et al. | The serotypes of Streptococcus pyogenes present in Britain during 1980-1990 and their association with disease. | 1993 | J. Med. Microbiol. | pmid:8366514 |
Chen SC et al. | Susceptibility of Legionella species to antimicrobial agents. | 1993 | Pathology | pmid:8367199 |
Hocking MP | Postoperative gastroparesis and tachygastria--response to electric stimulation and erythromycin. | 1993 | Surgery | pmid:8367808 |
Kaufman HS et al. | The effect of erythromycin on motility of the duodenum, sphincter of Oddi, and gallbladder in the prairie dog. | 1993 | Surgery | pmid:8367809 |
Hill AD et al. | Erythromycin improves emptying of the denervated stomach after oesophagectomy. | 1993 | Br J Surg | pmid:8369924 |
Culbertson WW et al. | Effective treatment of phlyctenular keratoconjunctivitis with oral tetracycline. | 1993 | Ophthalmology | pmid:8371924 |
Tomomasa T et al. | Erythromycin increases gastric antral motility in human premature infants. | 1993 | Biol. Neonate | pmid:8373908 |
Morgan AJ and Winters C | Immunolocalization of metallothionein (MT), and X.R.M.A. localization of zinc in hamster skin. | 1993 | Cell Biol. Int. | pmid:8374604 |
Yamashita K et al. | Sensitive high-performance liquid chromatographic determination of EM523, a new erythromycin derivative, in human plasma and urine with ultraviolet detection using column switching. | 1993 | J. Chromatogr. | pmid:8376485 |
Holdcroft C | Two new macrolide antibiotics: clarithromycin and azithromycin. | 1993 | Nurse Pract | pmid:8380492 |
Steele RJ and Meyer DR | Nasolacrimal duct obstruction and acute dacryocystitis associated with infectious mononucleosis (Epstein-Barr virus) | 1993 | Am. J. Ophthalmol. | pmid:8381586 |
Spangler SK and Appelbaum PC | Oxyrase, a method which avoids CO2 in the incubation atmosphere for anaerobic susceptibility testing of antibiotics affected by CO2. | 1993 | J. Clin. Microbiol. | pmid:8381817 |
Wyrick PB et al. | In-vitro activity of azithromycin on Chlamydia trachomatis infected, polarized human endometrial epithelial cells. | 1993 | J. Antimicrob. Chemother. | pmid:8383102 |
Nahata MC et al. | Pharmacokinetics of azithromycin in pediatric patients after oral administration of multiple doses of suspension. | 1993 | Antimicrob. Agents Chemother. | pmid:8383944 |
Vaara M | Outer membrane permeability barrier to azithromycin, clarithromycin, and roxithromycin in gram-negative enteric bacteria. | 1993 | Antimicrob. Agents Chemother. | pmid:8383945 |
Morandini G et al. | Clinical efficacy of azithromycin in lower respiratory tract infections. | 1993 | J Chemother | pmid:8384658 |
Brown ST et al. | Azithromycin, rifabutin, and rifapentine for treatment and prophylaxis of Mycobacterium avium complex in rats treated with cyclosporine. | 1993 | Antimicrob. Agents Chemother. | pmid:8384809 |
Butler T and Girard AE | Comparative efficacies of azithromycin and ciprofloxacin against experimental Salmonella typhimurium infection in mice. | 1993 | J. Antimicrob. Chemother. | pmid:8385094 |
Hammerschlag MR | Azithromycin and clarithromycin. | 1993 | Pediatr Ann | pmid:8385308 |
Donadio S and Staver MJ | IS1136, an insertion element in the erythromycin gene cluster of Saccharopolyspora erythraea. | 1993 | Gene | pmid:8386127 |
Strle F et al. | Azithromycin versus doxycycline for treatment of erythema migrans: clinical and microbiological findings. | 1993 Mar-Apr | Infection | pmid:8387966 |
Wildfeuer A et al. | Uptake and subcellular distribution of azithromycin in human phagocytic cells. Demonstration of the antibiotic in neutrophil polymorphonuclear leucocytes and monocytes by autoradiography and electron microscopy. | 1993 | Arzneimittelforschung | pmid:8388213 |
Kobrehel G et al. | Erythromycin series. IV. Thin-layer chromatography of erythromycin, erythromycin oxime, erythromyclamine and their acyl derivatives. | 1977 | J. Chromatogr. | pmid:838822 |
Cameron DJ | Effectiveness of early Lyme disease treatment. | 1993 | Am. J. Med. | pmid:8388627 |
Malanoski GJ et al. | Effect of pH variation on the susceptibility of Helicobacter pylori to three macrolide antimicrobial agents and temafloxacin. | 1993 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:8388791 |
Hammerschlag MR et al. | Single dose of azithromycin for the treatment of genital chlamydial infections in adolescents. | 1993 | J. Pediatr. | pmid:8388950 |
Melski JW et al. | Primary and secondary erythema migrans in central Wisconsin. | 1993 | Arch Dermatol | pmid:8389536 |
Minguez F et al. | In vitro killing kinetics and postantibiotic effect of josamycin and other macrolides on several bacteria. | 1993 May-Jun | Chemotherapy | pmid:8389685 |
Ikerd TR and Koletar SL | In-vitro activity of ciprofloxacin, temafloxacin, azithromycin, clarithromycin and metronidazole against Giardia lamblia. | 1993 | J. Antimicrob. Chemother. | pmid:8390436 |
Bonnet M and Van der Auwera P | Preincubation of Haemophilus influenzae with subinhibitory concentrations of macrolides: influence on human neutrophil chemiluminescence. | 1993 | Antimicrob. Agents Chemother. | pmid:8390808 |
Gordillo ME et al. | In vitro activity of azithromycin against bacterial enteric pathogens. | 1993 | Antimicrob. Agents Chemother. | pmid:8390813 |
McDonald PJ et al. | Persistent effect of antibiotics on Staphylococcus aureus after exposure for limited periods of time. | 1977 | J. Infect. Dis. | pmid:839090 |
Ghali R et al. | Erythromycin-associated ergotamine intoxication: arteriographic and electrophysiologic analysis of a rare cause of severe ischemia of the lower extremities and associated ischemic neuropathy. | 1993 | Ann Vasc Surg | pmid:8391300 |
Rodewald LE and Pichichero ME | Compliance with antibiotic therapy: a comparison of deuterium oxide tracer, urine bioassay, bottle weights, and parental reports. | 1993 | J. Pediatr. | pmid:8391566 |
Vargas SL et al. | Azithromycin for treatment of severe Cryptosporidium diarrhea in two children with cancer. | 1993 | J. Pediatr. | pmid:8391567 |
Sanz A et al. | Extraction-spectrofluorimetric method for the determination of erythromycin and its esters in pharmaceutical formulations using manual and flow-injection procedures. | 1993 | Analyst | pmid:8391764 |
Fayer R and Ellis W | Glycoside antibiotics alone and combined with tetracyclines for prophylaxis of experimental cryptosporidiosis in neonatal BALB/c mice. | 1993 | J. Parasitol. | pmid:8392541 |
Molinari G et al. | Inhibition of Pseudomonas aeruginosa virulence factors by subinhibitory concentrations of azithromycin and other macrolide antibiotics. | 1993 | J. Antimicrob. Chemother. | pmid:8392997 |
Wathne B et al. | Erythromycin versus metronidazole in the treatment of bacterial vaginosis. | 1993 | Acta Obstet Gynecol Scand | pmid:8394627 |
Gingras BA and Jensen JB | Antimalarial activity of azithromycin and erythromycin against Plasmodium berghei. | 1993 | Am. J. Trop. Med. Hyg. | pmid:8394660 |
Mansoor GA et al. | Azithromycin-induced acute interstitial nephritis. | 1993 | Ann. Intern. Med. | pmid:8395778 |
Panteix G et al. | In-vitro concentration of azithromycin in human phagocytic cells. | 1993 | J. Antimicrob. Chemother. | pmid:8396080 |
Rodriguez-Solares A et al. | A comparative study of the efficacy, safety and tolerance of azithromycin, dicloxacillin and flucloxacillin in the treatment of children with acute skin and skin-structure infections. | 1993 | J. Antimicrob. Chemother. | pmid:8396081 |
Hopkins S | Clinical safety and tolerance of azithromycin in children. | 1993 | J. Antimicrob. Chemother. | pmid:8396082 |
Lo Bue AM et al. | Efficacy of azithromycin compared with spiramycin in the treatment of odontogenic infections. | 1993 | J. Antimicrob. Chemother. | pmid:8396083 |
Amaya-Tapia G et al. | Once-daily azithromycin in the treatment of adult skin and skin-structure infections. | 1993 | J. Antimicrob. Chemother. | pmid:8396084 |
Müller O | Comparison of azithromycin versus clarithromycin in the treatment of patients with upper respiratory tract infections. | 1993 | J. Antimicrob. Chemother. | pmid:8396085 |
Hoepelman AI et al. | A single-blind comparison of three-day azithromycin and ten-day co-amoxiclav treatment of acute lower respiratory tract infections. | 1993 | J. Antimicrob. Chemother. | pmid:8396086 |
Bradbury F | Comparison of azithromycin versus clarithromycin in the treatment of patients with lower respiratory tract infection. | 1993 | J. Antimicrob. Chemother. | pmid:8396087 |
Myburgh J et al. | The efficacy and tolerance of a three-day course of azithromycin in the treatment of community-acquired pneumonia. | 1993 | J. Antimicrob. Chemother. | pmid:8396088 |
Girard D et al. | Comparison of azithromycin, roxithromycin, and cephalexin penetration kinetics in early and mature abscesses. | 1993 | J. Antimicrob. Chemother. | pmid:8396089 |
Fitzgeorge RB et al. | A comparison of the efficacy of azithromycin and clarithromycin in oral therapy of experimental airborne Legionnaires' disease. | 1993 | J. Antimicrob. Chemother. | pmid:8396090 |
Lauharanta J et al. | Single-dose oral azithromycin versus seven-day doxycycline in the treatment of non-gonococcal urethritis in males. | 1993 | J. Antimicrob. Chemother. | pmid:8396091 |
Lister PJ et al. | Comparison of azithromycin and doxycycline in the treatment of non-gonococcal urethritis in men. | 1993 | J. Antimicrob. Chemother. | pmid:8396092 |
Waugh MA | Open study of the safety and efficacy of a single oral dose of azithromycin for the treatment of uncomplicated gonorrhoea in men and women. | 1993 | J. Antimicrob. Chemother. | pmid:8396093 |
Girard AE et al. | The comparative activity of azithromycin, macrolides and amoxycillin against streptococci in experimental infections. | 1993 | J. Antimicrob. Chemother. | pmid:8396094 |
Foulds G and Johnson RB | Selection of dose regimens of azithromycin . | 1993 | J. Antimicrob. Chemother. | pmid:8396095 |
Retsema JA et al. | Preferential concentration of azithromycin in an infected mouse thigh model. | 1993 | J. Antimicrob. Chemother. | pmid:8396096 |
Wildfeuer A et al. | Comparison of the pharmacokinetics of three-day and five-day regimens of azithromycin in plasma and urine. | 1993 | J. Antimicrob. Chemother. | pmid:8396097 |
Mazzei T et al. | Pharmacokinetics of azithromycin in patients with impaired hepatic function. | 1993 | J. Antimicrob. Chemother. | pmid:8396098 |
Daniel RR | Comparison of azithromycin and co-amoxiclav in the treatment of otitis media in children. | 1993 | J. Antimicrob. Chemother. | pmid:8396099 |
Mohs E et al. | A comparative study of azithromycin and amoxycillin in paediatric patients with acute otitis media. | 1993 | J. Antimicrob. Chemother. | pmid:8396100 |
Schaad UB | Multicentre evaluation of azithromycin in comparison with co-amoxiclav for the treatment of acute otitis media in children. | 1993 | J. Antimicrob. Chemother. | pmid:8396101 |
Hamill J | Multicentre evaluation of azithromycin and penicillin V in the treatment of acute streptococcal pharyngitis and tonsillitis in children. | 1993 | J. Antimicrob. Chemother. | pmid:8396102 |
Weippl G | Multicentre comparison of azithromycin versus erythromycin in the treatment of paediatric pharyngitis or tonsillitis caused by group A streptococci. | 1993 | J. Antimicrob. Chemother. | pmid:8396103 |
Rumpianesi F et al. | In vitro activity of azithromycin against Chlamydia trachomatis, Ureaplasma urealyticum and Mycoplasma hominis in comparison with erythromycin, roxithromycin and minocycline. | 1993 | J Chemother | pmid:8396626 |
Gallar P et al. | Gastroparesis: an important cause of hospitalization in continuous ambulatory peritoneal dialysis patients and the role of erythromycin. | 1993 | Perit Dial Int | pmid:8399560 |
Waites KB et al. | Therapeutic considerations for Ureaplasma urealyticum infections in neonates. | 1993 | Clin. Infect. Dis. | pmid:8399918 |
Kenny GE and Cartwright FD | Effect of pH, inoculum size, and incubation time on the susceptibility of Ureaplasma urealyticum to erythromycin in vitro. | 1993 | Clin. Infect. Dis. | pmid:8399919 |
Zennaro E et al. | Dependence of cytoplasmic on mitochondrial protein synthesis in K. Lactis CBS 2360. I. Biochemical analysis. | 1977 | Mol. Gen. Genet. | pmid:840223 |
Algeri A et al. | Dependence of cytoplasmic on mitochondrial protein synthesis in K. lactis CBS 2360. II. Genetic studies. | 1977 | Mol. Gen. Genet. | pmid:840224 |
Navarro H et al. | Effect of erythromycin on D-galactose absorption and sucrase activity in rabbit jejunum. | 1993 Mar-Apr | Can. J. Physiol. Pharmacol. | pmid:8402381 |
Zapp ML et al. | Small molecules that selectively block RNA binding of HIV-1 Rev protein inhibit Rev function and viral production. | 1993 | Cell | pmid:8402886 |
Rubart M et al. | Electrophysiological mechanisms in a canine model of erythromycin-associated long QT syndrome. | 1993 | Circulation | pmid:8403329 |
Hughes J and Burrows NP | Infectious mononucleosis presenting as erythema multiforme. | 1993 | Clin. Exp. Dermatol. | pmid:8403481 |
Umeki S | Anti-inflammatory action of erythromycin. Its inhibitory effect on neutrophil NADPH oxidase activity. | 1993 | Chest | pmid:8404190 |
Kobrehel G et al. | 9a,11-cyclic carbamates of 15-membered azalides. | 1993 | J. Antibiot. | pmid:8407586 |