erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Vagus Nerve Injuries D061223 1 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Marchese A et al. Macrolide resistance mechanisms and expression of phenotypes among Streptococcus pneumoniae circulating in Italy. 1999 J. Antimicrob. Chemother. pmid:10588306
Wilson R et al. Five day moxifloxacin therapy compared with 7 day clarithromycin therapy for the treatment of acute exacerbations of chronic bronchitis. 1999 J. Antimicrob. Chemother. pmid:10588312
Panagea S et al. Should clindamycin be used as treatment of patients with infections caused by erythromycin-resistant staphylococci? 1999 J. Antimicrob. Chemother. pmid:10588329
Varaldo PE et al. Nationwide survey in Italy of treatment of Streptococcus pyogenes pharyngitis in children: influence of macrolide resistance on clinical and microbiological outcomes. Artemis-Italy Study Group. 1999 Clin. Infect. Dis. pmid:10589905
Glass D et al. A placebo-controlled clinical trial to compare a gel containing a combination of isotretinoin (0.05%) and erythromycin (2%) with gels containing isotretinoin (0.05%) or erythromycin (2%) alone in the topical treatment of acne vulgaris. 1999 Dermatology (Basel) pmid:10592405
Debbia EA [Antibiotic resistance: an always present problem]. 1999 Recenti Prog Med pmid:10592734
Brixius B et al. [Ventricular tachycardia after erythromycin administration in a newborn with congenital AV-block]. 1999 Nov-Dec Klin Padiatr pmid:10592929
Damkier P et al. Effect of diclofenac, disulfiram, itraconazole, grapefruit juice and erythromycin on the pharmacokinetics of quinidine. 1999 Br J Clin Pharmacol pmid:10594487
Doumith M et al. Interspecies complementation in Saccharopolyspora erythraea : elucidation of the function of oleP1, oleG1 and oleG2 from the oleandomycin biosynthetic gene cluster of Streptomyces antibioticus and generation of new erythromycin derivatives. 1999 Mol. Microbiol. pmid:10594828
Portillo A et al. Macrolide resistance phenotypes and mechanisms of resistance in Streptococcus pyogenes in La Rioja, Spain. 1999 Int. J. Antimicrob. Agents pmid:10595574
Sugiyama Y et al. Effects of long-term administration of erythromycin on cytokine production in rat alveolar macrophages. 1999 Eur. Respir. J. pmid:10596699
Polk RE et al. Pharmacokinetic interaction between ketoconazole and amprenavir after single doses in healthy men. 1999 Pharmacotherapy pmid:10600086
Esposito S et al. In vitro activity of moxifloxacin compared to other fluoroquinolones against different erythromycin-resistant phenotypes of group A beta-hemolytic streptococcus. 2000 Jan-Feb Chemotherapy pmid:10601794
Fluhr JW et al. In-vitro and in-vivo efficacy of zinc acetate against propionibacteria alone and in combination with erythromycin. 1999 Zentralbl. Bakteriol. pmid:10603662
Marre R and Trautmann M [Community-acquired respiratory tract infections. Current data on the efficacy of various classes of antibiotics and antibiotic resistance of the main prevalent bacteria species]. 1999 Med. Klin. (Munich) pmid:10603732
Ku YY et al. Synthesis and antibacterial activities of novel 12-O-methylerythromycin A derivatives. 1999 J. Antibiot. pmid:10604761
Ianaro A et al. Anti-inflammatory activity of macrolide antibiotics. 2000 J. Pharmacol. Exp. Ther. pmid:10604943
Sato Y et al. Adjuvant effect of a 14-member macrolide antibiotic on DNA vaccine. 1999 Cell. Immunol. pmid:10607432
Wang JS et al. Fluvoxamine is a more potent inhibitor of lidocaine metabolism than ketoconazole and erythromycin in vitro. 1999 Pharmacol. Toxicol. pmid:10608481
Honein MA et al. Infantile hypertrophic pyloric stenosis after pertussis prophylaxis with erythromcyin: a case review and cohort study. 1999 Dec 18-25 Lancet pmid:10609814