erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Vagus Nerve Injuries D061223 1 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Moutard I et al. In vitro effects of spiramycin and dirithromycin on IL1 beta production by human LPS-stimulated mononuclear cells. 1999 Sep-Oct Therapie pmid:10667098
Mordi MN et al. Acid-catalyzed degradation of clarithromycin and erythromycin B: a comparative study using NMR spectroscopy. 2000 J. Med. Chem. pmid:10669574
Munroe CO and Lazarus TL Prevention of infective endocarditis. 1976 Dent J pmid:1067255
Gibson J et al. Oral staphylococcal mucositis: A new clinical entity in orofacial granulomatosis and Crohn's disease. 2000 Oral Surg Oral Med Oral Pathol Oral Radiol Endod pmid:10673652
Holen S Antibiotics used traditionally in periodontal therapy. 1976 J. Periodontol. pmid:1067412
Biddle JW and Thornsberry C In vitro activity of rosamicin, josamycin, erythromycin, and clindamycin against beta-lactamase-nagative and beta-lactamase-positive strains of Neisseria gonorrhoeae. 1979 Antimicrob. Agents Chemother. pmid:106776
Kohri K et al. Macrolide antibiotics inhibit nitric oxide generation by rat pulmonary alveolar macrophages. 2000 Eur. Respir. J. pmid:10678622
Poyart C et al. Characterization of the Tn916-like transposon Tn3872 in a strain of abiotrophia defectiva (Streptococcus defectivus) causing sequential episodes of endocarditis in a child. 2000 Antimicrob. Agents Chemother. pmid:10681362
Tang X and Cheng D [The value of erythromycin pleurodesis in the treatment of malignant pleural effusions]. 1997 Hua Xi Yi Ke Da Xue Xue Bao pmid:10683963
Berg TG et al. Ureaplasma/Mycoplasma-infected amniotic fluid: pregnancy outcome in treated and nontreated patients. 1999 J Perinatol pmid:10685238
Fail PA et al. Comparative effects of quinacrine and erythromycin in adult female rats: a nonsurgical sterilization study. 2000 Fertil. Steril. pmid:10685548
Yamano K et al. Quantitative prediction of metabolic inhibition of midazolam by erythromycin, diltiazem, and verapamil in rats: implication of concentrative uptake of inhibitors into liver. 2000 J. Pharmacol. Exp. Ther. pmid:10688631
Noerr B Erythromycin. 1999 Neonatal Netw pmid:10690102
Thwaites RT and Frost JA Drug resistance in Campylobacter jejuni, C coli, and C lari isolated from humans in north west England and Wales, 1997. 1999 J. Clin. Pathol. pmid:10690169
Vardy SJ and Rose GE Prevention of cellulitis after open lacrimal surgery: a prospective study of three methods. 2000 Ophthalmology pmid:10690832
Hill BC et al. A simplified method for testing Bordetella pertussis for resistance to erythromycin and other antimicrobial agents. 2000 J. Clin. Microbiol. pmid:10699011
Timosca S et al. [Bacteremia following tooth extractions]. 1976 Rev Stomatol Chir Maxillofac pmid:1070098
Suri A et al. Effects of CYP3A inhibition on the metabolism of cilostazol. 1999 Clin Pharmacokinet pmid:10702888
Bernabéu JA et al. Microbiological bioassay of erythromycin thiocyanate: optimisation and validation. 1999 J Pharm Biomed Anal pmid:10703990
Brisaert M et al. Investigation of the chemical stability of an erythromycin-tretinoin lotion by the use of an optimization system. 2000 Int J Pharm pmid:10704802