MeSH term | MeSH ID | Detail |
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Vagus Nerve Injuries | D061223 | 1 associated lipids |
Drug-Related Side Effects and Adverse Reactions | D064420 | 3 associated lipids |
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Kyo S et al. | [Effects of macrolides on intracellular Ca2+ response by airway epithelium]. | 1998 | Jpn J Antibiot | pmid:9597513 |
Nakada M et al. | [Inhibitory effects of macrolide antibiotics at low concentrations on vero toxin production by pathogenic E. coli O157]. | 1998 | Jpn J Antibiot | pmid:9597511 |
Kozeki S et al. | [Study on bacterial biofilm destruction by various antibacterial agents]. | 1998 | Jpn J Antibiot | pmid:9597510 |
Yoshimine H et al. | [Inhibition of neutrophil-derived IL-8 production caused by EM (erythromycin) 201 derivative: modification of the activities by the 5-position desosamine side chain]. | 1998 | Jpn J Antibiot | pmid:9597508 |
Sugiyama Y et al. | [Changes in cytokine production by pulmonary alveolar macrophages collected from rats that have been treated with erythromycin for an extended period]. | 1998 | Jpn J Antibiot | pmid:9597506 |
Abe S et al. | [Effect of macrolides on IL-8 gene expression by cultured airway epithelial cells]. | 1998 | Jpn J Antibiot | pmid:9597504 |
Nishimura J et al. | [Effects of erythromycin on Pseudomonas aeruginosa pyocyanine-induced IL-8 production and its biological activity (the 2nd report)]. | 1998 | Jpn J Antibiot | pmid:9597503 |
Okura M et al. | [Multicenter study on clinical effects of a small dose of erythromycin on chronic lung disorders of premature infants--single blind comparison of treated and untreated groups. A committee for the Study of EM Therapy for Chronic Lung Diseases of Premature Infants]. | 1998 | Jpn J Antibiot | pmid:9597500 |
Miyazawa T et al. | [Mucous pathology and macrolide treatment of paranasal sinusitis in children]. | 1998 | Jpn J Antibiot | pmid:9597499 |
Kishi K et al. | [Study of efficacy of macrolide therapy applied to Kartagener's syndrome]. | 1998 | Jpn J Antibiot | pmid:9597497 |