erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Vagus Nerve Injuries D061223 1 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Salimi A et al. Toxicity of macrolide antibiotics on isolated heart mitochondria: a justification for their cardiotoxic adverse effect. 2016 Xenobiotica pmid:26068526
Zmantar T et al. Use of juglone as antibacterial and potential efflux pump inhibitors in Staphylococcus aureus isolated from the oral cavity. 2016 Microb. Pathog. pmid:27816681
Barbanti F and Spigaglia P Characterization of Clostridium difficile PCR-ribotype 018: A problematic emerging type. 2016 Anaerobe pmid:27725230
Mayor-Ibarguren A et al. Periorificial Lesions in a Young Girl. 2016 Actas Dermosifiliogr pmid:26935746
Hu P et al. Erythromycin triggers intussusception in a pediatric patient with Henoch-Schönlein purpura. 2016 Turk J Gastroenterol pmid:27782898
Heß S and Gallert C Growth Behavior of E. coli, Enterococcus and Staphylococcus Species in the Presence and Absence of Sub-inhibitory Antibiotic Concentrations: Consequences for Interpretation of Culture-Based Data. 2016 Microb. Ecol. pmid:27220972
Xu JY et al. Lysine Malonylome May Affect the Central Metabolism and Erythromycin Biosynthesis Pathway in Saccharopolyspora erythraea. 2016 J. Proteome Res. pmid:27090497
Parasrampuria DA et al. Edoxaban drug-drug interactions with ketoconazole, erythromycin, and cyclosporine. 2016 Br J Clin Pharmacol pmid:27530188
Hua CZ et al. [An analysis of 181 cases with blood stream infection caused by Streptococcus agalactiae in children from 2011 to 2015: a multi-center retrospective study]. 2016 Zhonghua Er Ke Za Zhi pmid:27510868
Johanesen P and Lyras D Methods for Determining Transfer of Mobile Genetic Elements in Clostridium difficile. 2016 Methods Mol. Biol. pmid:27507343
Barbanti F et al. Transfer of Clostridium difficile Genetic Elements Conferring Resistance to Macrolide-Lincosamide-Streptogramin B (MLSB) Antibiotics. 2016 Methods Mol. Biol. pmid:27507342
Gaglio R et al. Evaluation of antimicrobial resistance and virulence of enterococci from equipment surfaces, raw materials, and traditional cheeses. 2016 Int. J. Food Microbiol. pmid:27467501
Mikhail M et al. Orbital cellulitis and multiple abscess formation after strabismus surgery. 2016 Can. J. Ophthalmol. pmid:27085279
Chen Y et al. TEMPO-oxidized Konjac glucomannan as appliance for the preparation of hard capsules. 2016 Carbohydr Polym pmid:27083368
Del Grosso M et al. ICESpy009, a Conjugative Genetic Element Carrying mef(E) in Streptococcus pyogenes. 2016 Antimicrob. Agents Chemother. pmid:27067338
Aydin S Enhanced biodegradation of antibiotic combinations via the sequential treatment of the sludge resulting from pharmaceutical wastewater treatment using white-rot fungi Trametes versicolor and Bjerkandera adusta. 2016 Appl. Microbiol. Biotechnol. pmid:27033714
Shi HY et al. [Effect of quorum sensing system on the infection of MRSA and the intervention of erythromycin on it]. 2016 Zhonghua Yi Xue Za Zhi pmid:27760665
Lewis K et al. The efficacy and safety of prokinetic agents in critically ill patients receiving enteral nutrition: a systematic review and meta-analysis of randomized trials. 2016 Crit Care pmid:27527069
He HJ et al. Erythromycin resistance features and biofilm formation affected by subinhibitory erythromycin in clinical isolates of Staphylococcus epidermidis. 2016 J Microbiol Immunol Infect pmid:24768213
Katayama Y et al. Neuroprotective effects of erythromycin on ischemic injury following permanent focal cerebral ischemia in rats. 2016 Neurol. Res. pmid:27078702
Seefeldt AC et al. Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome. 2016 Nucleic Acids Res. pmid:26792896
Li M et al. Sugar-Grafted Cyclodextrin Nanocarrier as a "Trojan Horse" for Potentiating Antibiotic Activity. 2016 Pharm. Res. pmid:26792570
Lapierre L et al. Characterization of Antimicrobial Susceptibility and Its Association with Virulence Genes Related to Adherence, Invasion, and Cytotoxicity in Campylobacter jejuni and Campylobacter coli Isolates from Animals, Meat, and Humans. 2016 Microb. Drug Resist. pmid:26779841
Pan M and Chu LM Phytotoxicity of veterinary antibiotics to seed germination and root elongation of crops. 2016 Ecotoxicol. Environ. Saf. pmid:26773832
Rodrigues S et al. Acute and chronic effects of erythromycin exposure on oxidative stress and genotoxicity parameters of Oncorhynchus mykiss. 2016 Sci. Total Environ. pmid:26760278
Cheng Y et al. Comparative study between macrolide regulatory proteins MphR(A) and MphR(E) in ligand identification and DNA binding based on the rapid in vitro detection system. 2016 Anal Bioanal Chem pmid:26753969
Nenquin M and Henquin JC Sulphonylurea receptor-1, sulphonylureas and amplification of insulin secretion by Epac activation in β cells. 2016 Diabetes Obes Metab pmid:26584950
Wu H et al. In vivo investigation to the macrolide-glycosylating enzyme pair DesVII/DesVIII in Saccharopolyspora erythraea. 2016 Appl. Microbiol. Biotechnol. pmid:26552796
Berg L et al. [Cutaneous diphtheria after a minor injury in Sri Lanka]. 2016 Hautarzt pmid:26525966
Boetsch C et al. Effects of Cytochrome P450 3A4 Inhibitors-Ketoconazole and Erythromycin-on Bitopertin Pharmacokinetics and Comparison with Physiologically Based Modelling Predictions. 2016 Clin Pharmacokinet pmid:26341813
Giuliano MW and Miller SJ Site-Selective Reactions with Peptide-Based Catalysts. 2016 Top Curr Chem pmid:26307403
Hawkins PA et al. Cross-resistance to lincosamides, streptogramins A and pleuromutilins in Streptococcus agalactiae isolates from the USA. 2017 J. Antimicrob. Chemother. pmid:28333320
Demczuk WHB et al. Phylogenetic analysis of emergent Streptococcus pneumoniae serotype 22F causing invasive pneumococcal disease using whole genome sequencing. 2017 PLoS ONE pmid:28531208
Cheled-Shoval S et al. From Cell to Beak: In-Vitro and In-Vivo Characterization of Chicken Bitter Taste Thresholds. 2017 Molecules pmid:28513558
Sato T et al. Mycoplasma bovis isolates from dairy calves in Japan have less susceptibility than a reference strain to all approved macrolides associated with a point mutation (G748A) combined with multiple species-specific nucleotide alterations in 23S rRNA. 2017 Microbiol. Immunol. pmid:28504455
Wozniak A et al. Importance of adhesins in the recurrence of pharyngeal infections caused by Streptococcus pyogenes. 2017 J. Med. Microbiol. pmid:28463664
Pavlova A et al. Toward the rational design of macrolide antibiotics to combat resistance. 2017 Chem Biol Drug Des pmid:28419786
Szczepanska B et al. Prevalence and antimicrobial resistance of Campylobacter jejuni and Campylobacter coli isolated from children and environmental sources in urban and suburban areas. 2017 BMC Microbiol. pmid:28376713
Pergola S et al. Genetic diversity and antimicrobial resistance profiles of Campylobacter coli and Campylobacter jejuni isolated from broiler chicken in farms and at time of slaughter in central Italy. 2017 J. Appl. Microbiol. pmid:28194914
Huang YW et al. Overexpression of SmeDEF Efflux Pump Decreases Aminoglycoside Resistance in Stenotrophomonas maltophilia. 2017 Antimicrob. Agents Chemother. pmid:28193669
Ge LL et al. [Antibiotic resistance analysis of isolates from the hospitalized children in Shanxi Children's Hospital from 2012 to 2014]. 2017 Zhonghua Er Ke Za Zhi pmid:28173648
Giguère S Treatment of Infections Caused by Rhodococcus equi. 2017 Vet. Clin. North Am. Equine Pract. pmid:28161038
Wang Y et al. Evaluation of a series of 2-napthamide derivatives as inhibitors of the drug efflux pump AcrB for the reversal of antimicrobial resistance. 2017 Bioorg. Med. Chem. Lett. pmid:28129976
Owen L et al. A Multifactorial Comparison of Ternary Combinations of Essential Oils in Topical Preparations to Current Antibiotic Prescription Therapies for the Control of Acne Vulgaris-Associated Bacteria. 2017 Phytother Res pmid:28124400
Kassem II et al. Antimicrobial-Resistant Campylobacter in Organically and Conventionally Raised Layer Chickens. 2017 Foodborne Pathog. Dis. pmid:27768387
Song KH et al. Characteristics of cefazolin inoculum effect-positive methicillin-susceptible staphylococcus aureus infection in a multicentre bacteraemia cohort. 2017 Eur. J. Clin. Microbiol. Infect. Dis. pmid:27714592
Austin BA and Fleischer AB The extinction of topical erythromycin therapy for acne vulgaris and concern for the future of topical clindamycin. 2017 J Dermatolog Treat pmid:27425633
Jakubů V et al. Trends in the Minimum Inhibitory Concentrations of Erythromycin, Clarithromycin, Azithromycin, Ciprofloxacin, and Trimethoprim/Sulfamethoxazole for Strains of Bordetella pertussis isolated in the Czech Republic in 1967-2015. 2017 Cent. Eur. J. Public Health pmid:29346850
Duelge KJ et al. An LC-MS/MS method for the determination of antibiotic residues in distillers grains. 2017 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:28415016
Michael-Kordatou I et al. On the capacity of ozonation to remove antimicrobial compounds, resistant bacteria and toxicity from urban wastewater effluents. 2017 J. Hazard. Mater. pmid:26947803