MeSH term | MeSH ID | Detail |
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Abnormalities, Multiple | D000015 | 13 associated lipids |
Abnormalities, Drug-Induced | D000014 | 10 associated lipids |
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Dubois J and St-Pierre C | Comparative in vitro activity and post-antibiotic effect of gemifloxacin against Legionella spp. | 2000 | J. Antimicrob. Chemother. | pmid:10824031 |
Lee B | Progressive respiratory distress in an infant treated for presumed pertussis. | 2000 | Pediatr. Infect. Dis. J. | pmid:10819348 |
Ueno N et al. | Erythromycin improves glycaemic control in patients with Type II diabetes mellitus. | 2000 | Diabetologia | pmid:10819233 |
Munckhof WJ et al. | Postantibiotic suppression of growth of erythromycin A-susceptible and -resistant gram-positive bacteria by the ketolides telithromycin (HMR 3647) and HMR 3004. | 2000 | Antimicrob. Agents Chemother. | pmid:10817748 |
Terashi K et al. | Interactions of ofloxacin and erythromycin with the multidrug resistance protein (MRP) in MRP-overexpressing human leukemia cells. | 2000 | Antimicrob. Agents Chemother. | pmid:10817732 |
Capobianco JO et al. | Studies of the novel ketolide ABT-773: transport, binding to ribosomes, and inhibition of protein synthesis in Streptococcus pneumoniae. | 2000 | Antimicrob. Agents Chemother. | pmid:10817709 |
Bingen E et al. | Resistance to macrolides in Streptococcus pyogenes in France in pediatric patients. | 2000 | Antimicrob. Agents Chemother. | pmid:10817692 |
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Rao GG | Should clindamycin be used in treatment of patients with infections caused by erythromycin-resistant staphylococci? | 2000 | J. Antimicrob. Chemother. | pmid:10797103 |
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Gaisser S et al. | A defined system for hybrid macrolide biosynthesis in Saccharopolyspora erythraea. | 2000 | Mol. Microbiol. | pmid:10792725 |
Emerson BB et al. | Hemophilus influenzae type B susceptibility to 17 antibiotics. | 1975 | J. Pediatr. | pmid:1079251 |
Khan SA et al. | Transfer of erythromycin resistance from poultry to human clinical strains of Staphylococcus aureus. | 2000 | J. Clin. Microbiol. | pmid:10790109 |
Hoey J | Hypertrophic pyloric stenosis caused by erythromycin. | 2000 | CMAJ | pmid:10789643 |
Graham AE et al. | Efficient large-scale radical deoxygenation in alcoholic solvents using sodium hypophosphite and a phase-transfer agent: application to erythromycins. | 2000 | J. Org. Chem. | pmid:10789478 |
Schwarz UI et al. | P-glycoprotein inhibitor erythromycin increases oral bioavailability of talinolol in humans. | 2000 | Int J Clin Pharmacol Ther | pmid:10783825 |
Fanos V et al. | Flurithromycin-induced acute interstitial nephritis. | 2000 | Pediatr. Infect. Dis. J. | pmid:10783037 |
Clark RF et al. | Synthesis and antibacterial activity of novel 6-O-substituted erythromycin A derivatives. | 2000 | Bioorg. Med. Chem. Lett. | pmid:10782693 |
Sartakova M et al. | Development of an extrachromosomal cloning vector system for use in Borrelia burgdorferi. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10781091 |
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Donders GG | Treatment of sexually transmitted bacterial diseases in pregnant women. | 2000 | Drugs | pmid:10776830 |
Matsuoka M | [Study of macrolide, lincosamide, and streptogramin B antibiotics resistance in Staphylococcus aureus]. | 2000 | Yakugaku Zasshi | pmid:10774259 |
Gunics G et al. | Interaction between antibiotics and non-conventional antibiotics on bacteria. | 2000 | Int. J. Antimicrob. Agents | pmid:10773495 |
Pai MP et al. | Macrolide drug interactions: an update. | 2000 | Ann Pharmacother | pmid:10772438 |
Najib MM et al. | Cost-effectiveness of sparfloxacin compared with other oral antimicrobials in outpatient treatment of community-acquired pneumonia. | 2000 | Pharmacotherapy | pmid:10772376 |
Ghidini A et al. | Successful outcome after antibiotic treatment of postamniocentesis membrane rupture and chorioamnionitis in multiple pregnancy. | 1999 | Am J Perinatol | pmid:10772199 |
Roussel AJ et al. | Prokinetic effects of erythromycin on the ileum, cecum, and pelvic flexure of horses during the postoperative period. | 2000 | Am. J. Vet. Res. | pmid:10772107 |
Nieto JE et al. | In vitro effects of erythromycin, lidocaine, and metoclopramide on smooth muscle from the pyloric antrum, proximal portion of the duodenum, and middle portion of the jejunum of horses. | 2000 | Am. J. Vet. Res. | pmid:10772106 |
Suwa M et al. | Identification of two polyketide synthase gene clusters on the linear plasmid pSLA2-L in Streptomyces rochei. | 2000 | Gene | pmid:10767533 |
Quirós LM et al. | Glycosylation of macrolide antibiotics. Purification and kinetic studies of a macrolide glycosyltransferase from Streptomyces antibioticus. | 2000 | J. Biol. Chem. | pmid:10766792 |
Osterholm MT | Erythromycin remains gold standard for treatment of pertussis in infants. | 2000 | Clin. Infect. Dis. | pmid:10766495 |
Evans AJ and Krentz AJ | Should cisapride be avoided in patients with diabetic gastroparesis? | 1999 Sep-Dec | J. Diabetes Complicat. | pmid:10765008 |
Miller P et al. | Neural and muscular receptors for motilin in the rabbit colon. | 2000 | Peptides | pmid:10764957 |
Douthwaite S et al. | Macrolide-ketolide inhibition of MLS-resistant ribosomes is improved by alternative drug interaction with domain II of 23S rRNA. | 2000 | Mol. Microbiol. | pmid:10760175 |
Van Herwaarden MA et al. | The effect of motilin agonist ABT-229 on gastro-oesophageal reflux, oesophageal motility and lower oesophageal sphincter characteristics in GERD patients. | 2000 | Aliment. Pharmacol. Ther. | pmid:10759625 |
Curran JB et al. | Infection of abnormal heart valves and total joint prosthesis following dental procedures. | 1976 Jul-Aug | Northwest Dent | pmid:1075923 |
Fowler SM et al. | Amino acid 305 determines catalytic center accessibility in CYP3A4. | 2000 | Biochemistry | pmid:10757990 |
Cojocaru I et al. | [Dermatologic preparations with erythromycin--the correlation of the pharmaceutical form-therapeutic effect]. | 1997 Jul-Dec | Rev Med Chir Soc Med Nat Iasi | pmid:10756791 |