erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hoarseness D006685 2 associated lipids
Occupational Injuries D060051 1 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Liu L et al. [Synthesis of derivatives of (9S)-12-methylene erythromycin and their antibacterial activity in vitro]. 2005 Yao Xue Xue Bao pmid:16220785
Chen HX et al. [Compound erythromycin sustained release preparation and its in vitro release]. 2011 Yao Xue Xue Bao pmid:22260035
Watanabe Y et al. [Relationship between quality and serum level after the oral administration of commercial erythromycin tablets in man (author's transl)]. 1977 Yakugaku Zasshi pmid:911413
Matsuoka M [Study of macrolide, lincosamide, and streptogramin B antibiotics resistance in Staphylococcus aureus]. 2000 Yakugaku Zasshi pmid:10774259
Nakamura H et al. Effect of particle size on mixing degree in dispensation. 2004 Yakugaku Zasshi pmid:15049131
Nakamura H et al. Effect of mixing method on the mixing degree during the preparation of triturations. 2004 Yakugaku Zasshi pmid:15049130
Watanabe Y et al. [Effect of dissolving pH of enteric coating agent on bioavailability of enteric coated tablets of erythromycin in man (author's transl)]. 1978 Yakugaku Zasshi pmid:30834
Miyazaki M et al. [Trends and antimicrobial susceptibilities of clinical methicillin-resistant Staphylococcus aureus isolates in Fukuoka University Chikushi Hospital 2008-2012]. 2014 Yakugaku Zasshi pmid:24492229
Otsuka M et al. [Studies on fungicides. XIV. Effect of erythromycin on the growth of fungal mycelia (author's transl)]. 1978 Yakugaku Zasshi pmid:566318
Zhang Y et al. [Erythromycin restores oxidative stress-induced corticosteroid responsiveness of human THP-1 cells by up-regulating the expression of histone deacetylase 2]. 2014 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi pmid:24721407
Hu J et al. Possible multiple transporters were involved in hepatobiliary excretion of antofloxacin in rats. 2007 Xenobiotica pmid:17614005
Bickel MH et al. Entero-bacterial formation of cyclohexylamine in rats ingesting cyclamate. 1974 Xenobiotica pmid:4372812
Saitoh R et al. Nonlinear intestinal pharmacokinetics of mitemcinal, the first acid-resistant non-peptide motilin receptor agonist, in rats. 2007 Xenobiotica pmid:17926229
Berg-Candolfi M et al. Suppression of intestinal and hepatic cytochrome P4503A in murine Toxoplasma infection. Effects of N-acetylcysteine and N(G)-monomethyl-L-arginine on the hepatic suppression. 1996 Xenobiotica pmid:9173679
Villa P et al. Erythromycin toxicity in primary cultures of rat hepatocytes. 1985 Aug-Sep Xenobiotica pmid:4072263
Ward KW et al. Exploration of the African green monkey as a preclinical pharmacokinetic model: oral pharmacokinetic parameters and drug-drug interactions. 2009 Xenobiotica pmid:19280525
Kaye B and Roberts DW The metabolism of oxamniquine in the gut wall. 1980 Xenobiotica pmid:7395269
Kubo JI et al. Pharmacokinetic evaluation of high pulmonary disposition of clarithromycin after systemic administration. 2002 Xenobiotica pmid:12419017
Guillouzo A et al. Human hepatocyte cultures: a model of pharmaco-toxicological studies. 1985 Aug-Sep Xenobiotica pmid:3907158
Kanazu T et al. Model for the drug-drug interaction responsible for CYP3A enzyme inhibition. I: evaluation of cynomolgus monkeys as surrogates for humans. 2004 Xenobiotica pmid:15370956