MeSH term | MeSH ID | Detail |
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Hoarseness | D006685 | 2 associated lipids |
Occupational Injuries | D060051 | 1 associated lipids |
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Khair OA et al. | Effect of erythromycin on Haemophilus influenzae endotoxin-induced release of IL-6, IL-8 and sICAM-1 by cultured human bronchial epithelial cells. | 1995 | Eur. Respir. J. | pmid:8575568 |
Kerr JR and Moore JE | Potential for erythromycin resistance in porcine Campylobacter species. | 1995 | Trends Microbiol. | pmid:8574518 |
Lynch HC and Bushell ME | The physiology of erythromycin biosynthesis in cyclic fed batch culture. | 1995 | Microbiology (Reading, Engl.) | pmid:8574403 |
Goswami BB et al. | Physico-chemical properties and biological activities of erythromycin nalidixate. | 1995 | Arzneimittelforschung | pmid:8573228 |
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Allen NE | Macrolide resistance in Staphylococcus aureus: inducers of macrolide resistance. | 1977 | Antimicrob. Agents Chemother. | pmid:856018 |
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Mitsuyama T et al. | Inhibition by erythromycin of superoxide anion production by human polymorphonuclear leukocytes through the action of cyclic AMP-dependent protein kinase. | 1995 | Respiration | pmid:8560094 |
Tauch A et al. | The Corynebacterium xerosis composite transposon Tn5432 consists of two identical insertion sequences, designated IS1249, flanking the erythromycin resistance gene ermCX. | 1995 | Plasmid | pmid:8559800 |
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Fujii T et al. | Long term effect of erythromycin therapy in patients with chronic Pseudomonas aeruginosa infection. | 1995 | Thorax | pmid:8553295 |
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Bojar RA et al. | Direct analysis of resistance in the cutaneous microflora during treatment of acne vulgaris with topical 1% nadifloxacin and 2% erythromycin. | 1995 | Drugs | pmid:8549289 |
Stein CM et al. | Comparison of the dapsone recovery ratio and the erythromycin breath test as in vivo probes of CYP3A activity in patients with rheumatoid arthritis receiving cyclosporine. | 1996 | Clin. Pharmacol. Ther. | pmid:8549033 |
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Littenberg B et al. | A randomized controlled trial of oral albuterol in acute cough. | 1996 | J Fam Pract | pmid:8537805 |
Hosie J et al. | A comparison of 5 days of dirithromycin and 7 days of clarithromycin in acute bacterial exacerbation of chronic bronchitis. | 1995 | J. Antimicrob. Chemother. | pmid:8537264 |
Doucet-Populaire F et al. | Acquired resistance in Mycobacterium avium complex strains isolated from AIDS patients and beige mice during treatment with clarithromycin. | 1995 | J. Antimicrob. Chemother. | pmid:8537260 |
Shiba Y et al. | Effect of nonpeptide motilin agonist EM523 on release of gut and pancreatic hormones in conscious dogs. | 1996 | Gastroenterology | pmid:8536863 |
Hoppe JE and Tschirner T | Comparison of media for agar dilution susceptibility testing of Bordetella pertussis and Bordetella parapertussis. | 1995 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:8536725 |
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Benzamycin gel for acne. | 1995 | Drug Ther Bull | pmid:8529541 | |
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Tee W et al. | Emergence of multidrug resistance in Campylobacter jejuni isolates from three patients infected with human immunodeficiency virus. | 1995 | Clin. Infect. Dis. | pmid:8527556 |
Kelentey BA and Kelentey BJ | [Excretion of erythromycin, clindamycin and lincomycin into the saliva]. | 1995 | Fogorv Sz | pmid:8522016 |
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Nakata M et al. | Synthetic studies of erythromycin derivatives. Synthesis and antimicrobial activities of 3''-EPI-erythromycin A and (9S)-11-dehydroxy-9-deoxo-9-hydroxy-11- oxoerythromycin A. | 1993 | J. Antibiot. | pmid:8514636 |
Kepczyk T et al. | Effect of intravenous erythromycin on gastric emptying. | 1993 May-Jun | Gastrointest. Endosc. | pmid:8514093 |
Narchi P et al. | Interactions of pre-operative erythromycin administration with general anaesthesia. | 1993 | Can J Anaesth | pmid:8513524 |
Suata K et al. | Antimicrobial susceptibility patterns and resistance transferability among Bacteroides fragilis group isolates from patients with appendicitis in Bali, Indonesia. | 1993 | Clin. Infect. Dis. | pmid:8513066 |
Siminoski K | Persistent fever due to occult dental infection: case report and review. | 1993 | Clin. Infect. Dis. | pmid:8513063 |
Varga DW | Learning in the real world. | 1993 | J Ky Med Assoc | pmid:8509688 |
Roberts GA et al. | Heterologous expression in Escherichia coli of an intact multienzyme component of the erythromycin-producing polyketide synthase. | 1993 | Eur. J. Biochem. | pmid:8508800 |
Kawamura O et al. | Effect of erythromycin derivative EM523L on human interdigestive gastrointestinal tract. | 1993 | Dig. Dis. Sci. | pmid:8508696 |
Lemaire F et al. | [Erythromycin therapy of incidences of superinfection in chronic respiratory insufficiency]. | 1977 | Nouv Presse Med | pmid:850633 |
Altemeir WA and Ayoub EM | Erythromycin prophylaxis for pertussis. | 1977 | Pediatrics | pmid:850603 |
Danielson ND et al. | Simple methods for the qualitative identification and quantitative determination of macrolide antibiotics. | 1993 | J Pharm Biomed Anal | pmid:8504183 |
Sacristán JA et al. | Ototoxicity of erythromycin in man: electrophysiologic approach. | 1993 | Am J Otol | pmid:8503495 |
Oğünç G et al. | [Legionnaires' disease following kidney transplantation]. | 1993 | Mikrobiyol Bul | pmid:8502185 |
Faghin R et al. | Acid degradation studies of 6-deoxyerythromycin A. | 1993 | J. Antibiot. | pmid:8501017 |
Watanabe Y et al. | Chemical modification of erythromycins. IX. Selective methylation at the C-6 hydroxyl group of erythromycin A oxime derivatives and preparation of clarithromycin. | 1993 | J. Antibiot. | pmid:8501007 |
Levison ME et al. | In vitro activity and clinical efficacy of clindamycin in the treatment of infections due to anaerobic bacteria. | 1977 | J. Infect. Dis. | pmid:850091 |
Iino Y et al. | Erythromycin therapy for otitis media with effusion in sinobronchial syndrome. | 1993 | Arch. Otolaryngol. Head Neck Surg. | pmid:8499096 |
Prather CM et al. | Gastric axial forces in experimentally delayed and accelerated gastric emptying. | 1993 | Am. J. Physiol. | pmid:8498519 |
Tredaniel J et al. | Diffuse panbronchiolitis: efficacy of low-dose erythromycin. | 1993 | Respir Med | pmid:8497706 |
Edelstein PH and Edelstein MA | In vitro activity of RP 74501-RP 74502, a novel streptogramin antimicrobial mixture, against clinical isolates of Legionella species. | 1993 | Antimicrob. Agents Chemother. | pmid:8494390 |
Foweraker JE et al. | Ecology of Haemophilus influenzae and Haemophilus parainfluenzae in sputum and saliva and effects of antibiotics on their distribution in patients with lower respiratory tract infections. | 1993 | Antimicrob. Agents Chemother. | pmid:8494378 |
Tankovic J et al. | Antimicrobial susceptibility of Pediococcus spp. and genetic basis of macrolide resistance in Pediococcus acidilactici HM3020. | 1993 | Antimicrob. Agents Chemother. | pmid:8494376 |
Tateda K et al. | Effects of sub-MICs of erythromycin and other macrolide antibiotics on serum sensitivity of Pseudomonas aeruginosa. | 1993 | Antimicrob. Agents Chemother. | pmid:8494362 |
Piras G et al. | Cloning and sequencing of the low-affinity penicillin-binding protein 3r-encoding gene of Enterococcus hirae S185: modular design and structural organization of the protein. | 1993 | J. Bacteriol. | pmid:8491705 |
Grøndahl TO and Langmoen IA | Epileptogenic effect of antibiotic drugs. | 1993 | J. Neurosurg. | pmid:8487076 |
Soriano F and Fernández-Roblas R | High rates of erythromycin-resistant Streptococcus pneumoniae among penicillin-resistant strains. | 1993 | J. Antimicrob. Chemother. | pmid:8486579 |
Savolainen S et al. | Peritonsillar abscess. Clinical and microbiologic aspects and treatment regimens. | 1993 | Arch. Otolaryngol. Head Neck Surg. | pmid:8484941 |
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Rathore MH and Jenkins SG | Group A beta-hemolytic Streptococcus: issue of resistance. | 1993 | Pediatr. Infect. Dis. J. | pmid:8483636 |
Gustafsson BE et al. | Prolonged induction of germfree bile acid pattern in conventional rats by antibiotics. | 1977 | Acta Med Scand | pmid:848350 |
Orr PH et al. | Randomized placebo-controlled trials of antibiotics for acute bronchitis: a critical review of the literature. | 1993 | J Fam Pract | pmid:8482934 |
Ohtawa M et al. | Mechanism of gastroprokinetic effect of EM523, an erythromycin derivative, in dogs. | 1993 | Gastroenterology | pmid:8482446 |
Kawamura O et al. | Effect of erythromycin on interdigestive gastrointestinal contractile activity and plasma motilin concentration in humans. | 1993 | Dig. Dis. Sci. | pmid:8482186 |
Derby LE et al. | Erythromycin-associated cholestatic hepatitis. | 1993 | Med. J. Aust. | pmid:8479375 |
Müller O and Wettich K | Clinical efficacy of dirithromycin in pharyngitis and tonsillitis. | 1993 | J. Antimicrob. Chemother. | pmid:8478316 |
Derriennic M et al. | Dirithromycin in the treatment of streptococcal pharyngitis. | 1993 | J. Antimicrob. Chemother. | pmid:8478315 |
Bergogne-Bérézin E | Tissue distribution of dirithromycin: comparison with erythromycin. | 1993 | J. Antimicrob. Chemother. | pmid:8478314 |
Sides GD et al. | Pharmacokinetics of dirithromycin. | 1993 | J. Antimicrob. Chemother. | pmid:8478313 |
Labro MT et al. | Modulation of human polymorphonuclear neutrophil function by macrolides: preliminary data concerning dirithromycin. | 1993 | J. Antimicrob. Chemother. | pmid:8478312 |
Bauernfeind A | In-vitro activity of dirithromycin in comparison with other new and established macrolides. | 1993 | J. Antimicrob. Chemother. | pmid:8478311 |
Barry AL et al. | Dirithromycin disc susceptibility tests: interpretative criteria and quality control parameters. | 1993 | J. Antimicrob. Chemother. | pmid:8478310 |
Sides GD and Conforti PM | Safety profile of dirithromycin. | 1993 | J. Antimicrob. Chemother. | pmid:8478309 |
Varanese L | Pharmacokinetics and safety of dirithromycin in the elderly. | 1993 | J. Antimicrob. Chemother. | pmid:8478308 |
Derriennic M and Escande JP | Dirithromycin in the treatment of skin and skin structure infections. | 1993 | J. Antimicrob. Chemother. | pmid:8478307 |
Pozzi E | Clinical efficacy of dirithromycin versus miocamycin in the treatment of acute bronchitis or acute exacerbations of chronic bronchitis. | 1993 | J. Antimicrob. Chemother. | pmid:8478306 |
Gaillat J | A multicentre study comparing the safety and efficacy of dirithromycin with erythromycin in the treatment of bronchitis. | 1993 | J. Antimicrob. Chemother. | pmid:8478305 |
Sides GD | Clinical efficacy of dirithromycin in acute exacerbations of chronic bronchitis. | 1993 | J. Antimicrob. Chemother. | pmid:8478304 |
Jacobson K | Clinical efficacy of dirithromycin in pneumonia. | 1993 | J. Antimicrob. Chemother. | pmid:8478303 |
Ruggiero G et al. | Clinical efficacy of dirithromycin versus miocamycin in tonsillopharyngitis. | 1993 | J. Antimicrob. Chemother. | pmid:8478300 |
Endou K et al. | Implication of cohesive binding of a macrolide antibiotic, rokitamycin, to ribosomes from Staphylococcus aureus. | 1993 | J. Antibiot. | pmid:8478265 |
Husfeldt P et al. | Antibiotic treatment of sinusitis in general practice. A double-blind study comparing ofloxacin and erythromycin. | 1993 | Eur Arch Otorhinolaryngol | pmid:8476582 |
Gannon H | Ureaplasma urealyticum and its role in neonatal lung disease. | 1993 | Neonatal Netw | pmid:8474408 |
Garlaschi ML et al. | Antimicrobial resistance among clinical isolates of Haemophilus influenzae in northern Italy. Collaborative Study on Pediatric Infectious Diseases. | 1993 | Eur. J. Epidemiol. | pmid:8472803 |
Smith GR and Thornton EA | Effect of disturbance of the gastrointestinal microflora on the faecal excretion of Fusobacterium necrophorum biovar A. | 1993 | Epidemiol. Infect. | pmid:8472777 |