erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

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Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hoarseness D006685 2 associated lipids
Occupational Injuries D060051 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


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Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

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What genes are associated with erythromycin?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Khair OA et al. Effect of erythromycin on Haemophilus influenzae endotoxin-induced release of IL-6, IL-8 and sICAM-1 by cultured human bronchial epithelial cells. 1995 Eur. Respir. J. pmid:8575568
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Lynch HC and Bushell ME The physiology of erythromycin biosynthesis in cyclic fed batch culture. 1995 Microbiology (Reading, Engl.) pmid:8574403
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Roberts GA et al. Heterologous expression in Escherichia coli of an intact multienzyme component of the erythromycin-producing polyketide synthase. 1993 Eur. J. Biochem. pmid:8508800
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Watanabe Y et al. Chemical modification of erythromycins. IX. Selective methylation at the C-6 hydroxyl group of erythromycin A oxime derivatives and preparation of clarithromycin. 1993 J. Antibiot. pmid:8501007
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Edelstein PH and Edelstein MA In vitro activity of RP 74501-RP 74502, a novel streptogramin antimicrobial mixture, against clinical isolates of Legionella species. 1993 Antimicrob. Agents Chemother. pmid:8494390
Foweraker JE et al. Ecology of Haemophilus influenzae and Haemophilus parainfluenzae in sputum and saliva and effects of antibiotics on their distribution in patients with lower respiratory tract infections. 1993 Antimicrob. Agents Chemother. pmid:8494378
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Ohtawa M et al. Mechanism of gastroprokinetic effect of EM523, an erythromycin derivative, in dogs. 1993 Gastroenterology pmid:8482446
Kawamura O et al. Effect of erythromycin on interdigestive gastrointestinal contractile activity and plasma motilin concentration in humans. 1993 Dig. Dis. Sci. pmid:8482186
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Müller O and Wettich K Clinical efficacy of dirithromycin in pharyngitis and tonsillitis. 1993 J. Antimicrob. Chemother. pmid:8478316
Derriennic M et al. Dirithromycin in the treatment of streptococcal pharyngitis. 1993 J. Antimicrob. Chemother. pmid:8478315
Bergogne-Bérézin E Tissue distribution of dirithromycin: comparison with erythromycin. 1993 J. Antimicrob. Chemother. pmid:8478314
Sides GD et al. Pharmacokinetics of dirithromycin. 1993 J. Antimicrob. Chemother. pmid:8478313
Labro MT et al. Modulation of human polymorphonuclear neutrophil function by macrolides: preliminary data concerning dirithromycin. 1993 J. Antimicrob. Chemother. pmid:8478312
Bauernfeind A In-vitro activity of dirithromycin in comparison with other new and established macrolides. 1993 J. Antimicrob. Chemother. pmid:8478311
Barry AL et al. Dirithromycin disc susceptibility tests: interpretative criteria and quality control parameters. 1993 J. Antimicrob. Chemother. pmid:8478310
Sides GD and Conforti PM Safety profile of dirithromycin. 1993 J. Antimicrob. Chemother. pmid:8478309
Varanese L Pharmacokinetics and safety of dirithromycin in the elderly. 1993 J. Antimicrob. Chemother. pmid:8478308
Derriennic M and Escande JP Dirithromycin in the treatment of skin and skin structure infections. 1993 J. Antimicrob. Chemother. pmid:8478307
Pozzi E Clinical efficacy of dirithromycin versus miocamycin in the treatment of acute bronchitis or acute exacerbations of chronic bronchitis. 1993 J. Antimicrob. Chemother. pmid:8478306
Gaillat J A multicentre study comparing the safety and efficacy of dirithromycin with erythromycin in the treatment of bronchitis. 1993 J. Antimicrob. Chemother. pmid:8478305
Sides GD Clinical efficacy of dirithromycin in acute exacerbations of chronic bronchitis. 1993 J. Antimicrob. Chemother. pmid:8478304
Jacobson K Clinical efficacy of dirithromycin in pneumonia. 1993 J. Antimicrob. Chemother. pmid:8478303
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Smith GR and Thornton EA Effect of disturbance of the gastrointestinal microflora on the faecal excretion of Fusobacterium necrophorum biovar A. 1993 Epidemiol. Infect. pmid:8472777