MeSH term | MeSH ID | Detail |
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Hoarseness | D006685 | 2 associated lipids |
Occupational Injuries | D060051 | 1 associated lipids |
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Velicko I et al. | [Lymphogranuloma venereum--increased spread in Sweden. A rare Chlamydia subtype which become more and more common among men who have sex with men]. | 2009 Jan 7-13 | Lakartidningen | pmid:19235318 |
Galaction AI et al. | [Separation of erythromycin by direct pertraction from simulated broths]. | 2009 Apr-Jun | Rev Med Chir Soc Med Nat Iasi | pmid:21495378 |
Alexander RE and Grogan DM | Long-acting erythromycins: assessing their role in treating outpatient odontogenic infections. | 2009 | Tex Dent J | pmid:19472551 |
Kabir AR et al. | Management of bronchiolitis without antibiotics: a multicentre randomized control trial in Bangladesh. | 2009 | Acta Paediatr. | pmid:19572992 |
Ung D et al. | Metabolic interactions between prokinetic agents domperidone and erythromycin: an in vitro analysis. | 2009 | Xenobiotica | pmid:19575604 |
Roca I et al. | CraA, a major facilitator superfamily efflux pump associated with chloramphenicol resistance in Acinetobacter baumannii. | 2009 | Antimicrob. Agents Chemother. | pmid:19581458 |
SvetlÃková Z et al. | Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs. | 2009 | Antimicrob. Agents Chemother. | pmid:19581465 |
Xu P et al. | Synthesis of novel macrolide derivatives with imidazo[4,5-b]pyridinyl sulfur contained alkyl side chains and their antibacterial activity. | 2009 | Bioorg. Med. Chem. Lett. | pmid:19560350 |
Feld L et al. | Characterization of a small erythromycin resistance plasmid pLFE1 from the food-isolate Lactobacillus plantarum M345. | 2009 | Plasmid | pmid:19399991 |
Cheng YS et al. | Stress-induced cardiac insufficiency relating to abnormal leptin and FKBP12.6 is ameliorated by CPU0213, an endothelin receptor antagonist, which is not affected by the CYP3A suppressing effect of erythromycin. | 2009 | J. Pharm. Pharmacol. | pmid:19405994 |
Majumdar S et al. | Vitreal kinetics of quinidine in rabbits in the presence of topically coadministered P-glycoprotein substrates/modulators. | 2009 | Drug Metab. Dispos. | pmid:19406953 |
Zonenschain D et al. | Erythromycin- and tetracycline-resistant lactobacilli in Italian fermented dry sausages. | 2009 | J. Appl. Microbiol. | pmid:19426258 |
Bostan K et al. | Prevalence and antibiotic susceptibility of thermophilic Campylobacter species on beef, mutton, and chicken carcasses in Istanbul, Turkey. | 2009 | Microb. Drug Resist. | pmid:19432522 |
Pinheiro S et al. | Prevalence and mechanisms of erythromycin resistance in Streptococcus agalactiae from healthy pregnant women. | 2009 | Microb. Drug Resist. | pmid:19432524 |
Su JH et al. | Ferrous iron-binding protein Omb of Salmonella enterica serovar Choleraesuis promotes resistance to hydrophobic antibiotics and contributes to its virulence. | 2009 | Microbiology (Reading, Engl.) | pmid:19389759 |
Rendi-Wagner P et al. | National paediatric immunization program of high risk groups: no effect on the incidence of invasive pneumococcal diseases. | 2009 | Vaccine | pmid:19393711 |
Ohkura K et al. | Flexible structure of cytochrome P450: promiscuity of ligand binding in the CYP3A4 heme pocket. | 2009 | Anticancer Res. | pmid:19414330 |
Yu I et al. | [The effects of the erythromycin on the production of r-glutamylcys glutamylcysteine synthetase and glutathione in the bronchial epithelial cell]. | 2009 | Zhongguo Ying Yong Sheng Li Xue Za Zhi | pmid:21186628 |
Chu YW et al. | Resistance to tetracycline, erythromycin and clindamycin in Streptococcus suis serotype 2 in Hong Kong. | 2009 | Int. J. Antimicrob. Agents | pmid:19380213 |
Mehta N and Laddha KS | A modified method for isolation of rhein from senna. | 2009 | Indian J Pharm Sci | pmid:20336207 |
Ahmed AB et al. | Strain measurement during antral contractions by ultrasound strain rate imaging: influence of erythromycin. | 2009 | Neurogastroenterol. Motil. | pmid:18086208 |
Tateda K | [New Actions of macrolides. General topics. Summary of discussion. (2)]. | 2009 | Jpn J Antibiot | pmid:22454853 |
Yamaya M | [Effects of macrolides in preventing influenza and airway inflammation]. | 2009 | Jpn J Antibiot | pmid:22454856 |
Matsune S et al. | [EM900 and eosinophilic paranasal sinusitis]. | 2009 | Jpn J Antibiot | pmid:22442865 |
Lin HT et al. | MacB ABC transporter is a dimer whose ATPase activity and macrolide-binding capacity are regulated by the membrane fusion protein MacA. | 2009 | J. Biol. Chem. | pmid:18955484 |
Crider KS et al. | Antibacterial medication use during pregnancy and risk of birth defects: National Birth Defects Prevention Study. | 2009 | Arch Pediatr Adolesc Med | pmid:19884587 |
Paasche SR | Rhodococcus equi infection in a surgical wound. | 2009 | Clin Lab Sci | pmid:19827407 |
Beliaev AM et al. | Erythromycin-induced postprandial biliary colic. | 2009 | N. Z. Med. J. | pmid:19829393 |
de la Pedrosa EG et al. | High clonal diversity in erythromycin-resistant Streptococcus pneumoniae invasive isolates in Madrid, Spain (2000-07). | 2009 | J. Antimicrob. Chemother. | pmid:19837717 |
Huang SX et al. | Erythronolides H and I, new erythromycin congeners from a new halophilic actinomycete Actinopolyspora sp. YIM90600. | 2009 | Org. Lett. | pmid:19228040 |
Muri D and Carreira EM | Stereoselective synthesis of erythronolide A via nitrile oxide cycloadditions and related studies. | 2009 | J. Org. Chem. | pmid:19839571 |
Cooper WO et al. | Antibiotics potentially used in response to bioterrorism and the risk of major congenital malformations. | 2009 | Paediatr Perinat Epidemiol | pmid:19228311 |
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Banères-Roquet F et al. | Use of a surface plasmon resonance method to investigate antibiotic and plasma protein interactions. | 2009 | Antimicrob. Agents Chemother. | pmid:19164148 |
Huang XH et al. | [Establishment of a rat model of mycoplasma pneumonia and the treatment]. | 2009 | Nan Fang Yi Ke Da Xue Xue Bao | pmid:19923071 |
Lovmar M et al. | Erythromycin resistance by L4/L22 mutations and resistance masking by drug efflux pump deficiency. | 2009 | EMBO J. | pmid:19197244 |
Röhm KD et al. | Motility disorders in the ICU: recent therapeutic options and clinical practice. | 2009 | Curr Opin Clin Nutr Metab Care | pmid:19202387 |
Zou X et al. | Enhancement of erythromycin A production with feeding available nitrogen sources in erythromycin biosynthesis phase. | 2009 | Bioresour. Technol. | pmid:19268575 |
Maruyama K et al. | [Analysis of the mechanism involved in the effects of erythromycin in suppressing the development of pseudomembranous colitis]. | 2009 | Jpn J Antibiot | pmid:22452058 |
Fan Y et al. | Preparation and characteristics of erythromycin microspheres for lung targeting. | 2009 | Drug Dev Ind Pharm | pmid:19259878 |
Markel DC et al. | Inhibitory effects of erythromycin on wear debris-induced VEGF/Flt-1 gene production and osteolysis. | 2009 | Inflamm. Res. | pmid:19262986 |
Zheng J et al. | Structure and function of the macrolide biosensor protein, MphR(A), with and without erythromycin. | 2009 | J. Mol. Biol. | pmid:19265703 |
Zou X et al. | Oxygen uptake rate optimization with nitrogen regulation for erythromycin production and scale-up from 50 L to 372 m3 scale. | 2009 | Bioresour. Technol. | pmid:18929481 |
Chan JC et al. | Epidemiological analysis of Streptococcus pyogenes infections in Hong Kong. | 2009 | Pathology | pmid:20001348 |
Udayakumar D and Sanaullah M | Campylobacter cholecystitis. | 2009 | Int J Med Sci | pmid:19960123 |
Wehmeier C et al. | Site-directed mutagenesis reveals amino acid residues in the Escherichia coli RND efflux pump AcrB that confer macrolide resistance. | 2009 | Antimicrob. Agents Chemother. | pmid:18936189 |
Jeters RT et al. | Antibiotic resistance genes in the vaginal microbiota of primates not normally exposed to antibiotics. | 2009 | Microb. Drug Resist. | pmid:19857138 |
Williams GJ and Thorson JS | Natural product glycosyltransferases: properties and applications. | 2009 | Adv. Enzymol. Relat. Areas Mol. Biol. | pmid:18990828 |
Shaw SJ et al. | Structure-activity relationships of 9-substituted-9-dihydroerythromycin-based motilin agonists: optimizing for potency and safety. | 2009 | J. Med. Chem. | pmid:19821563 |
Mortison JD et al. | Synthesis and biochemical analysis of complex chain-elongation intermediates for interrogation of molecular specificity in the erythromycin and pikromycin polyketide synthases. | 2009 | J. Am. Chem. Soc. | pmid:19810731 |
Hariharan H et al. | Antimicrobial drug resistance as determined by the E-test in Campylobacter jejuni, C. coli, and C. lari isolates from the ceca of broiler and layer chickens in Grenada. | 2009 | Comp. Immunol. Microbiol. Infect. Dis. | pmid:18329712 |
Vila-Corcoles A et al. | Drug-resistance in Streptococcus pneumoniae isolates among Spanish middle aged and older adults with community-acquired pneumonia. | 2009 | BMC Infect. Dis. | pmid:19320989 |
Sader HS et al. | Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates. | 2009 | Antimicrob. Agents Chemother. | pmid:19289528 |
Razzaq A et al. | Erythromycin establishes early oral feeding in neonates operated for congenital intestinal atresias. | 2009 | Pediatr. Surg. Int. | pmid:19290531 |
Vachée A et al. | [Antibiotics susceptibility of Streptococcus and Enterococcus: data of Onerba network]. | 2009 | Pathol. Biol. | pmid:18343047 |
Lindqvist M et al. | A clonal outbreak of methicillin-susceptible Staphylococcus aureus with concomitant resistance to erythromycin, clindamycin and tobramycin in a Swedish county. | 2009 | Scand. J. Infect. Dis. | pmid:19294581 |
Sambo N et al. | Effect of the aqueous extract of Psidium guajava on erythromycin-induced liver damage in rats. | 2009 | Niger J Physiol Sci | pmid:20234760 |
Kumar S et al. | Ligand diversity of human and chimpanzee CYP3A4: activation of human CYP3A4 by lithocholic acid results from positive selection. | 2009 | Drug Metab. Dispos. | pmid:19299527 |
Picazo JJ | Management of antibiotic-resistant Streptococcus pneumoniae infections and the use of pneumococcal conjugate vaccines. | 2009 | Clin. Microbiol. Infect. | pmid:19366362 |
Sanger GJ et al. | GSK962040: a small molecule, selective motilin receptor agonist, effective as a stimulant of human and rabbit gastrointestinal motility. | 2009 | Neurogastroenterol. Motil. | pmid:19374732 |
Lahu G et al. | Effect of repeated dose of erythromycin on the pharmacokinetics of roflumilast and roflumilast N-oxide. | 2009 | Int J Clin Pharmacol Ther | pmid:19356389 |
Murayama SY et al. | Capsular type and antibiotic resistance in Streptococcus agalactiae isolates from patients, ranging from newborns to the elderly, with invasive infections. | 2009 | Antimicrob. Agents Chemother. | pmid:19332682 |
Zhang C et al. | Thiazomycins, thiazolyl peptide antibiotics from Amycolatopsis fastidiosa. | 2009 | J. Nat. Prod. | pmid:19334707 |
Afshari GR et al. | Effect of parenteral administration of ivermectin and erythromycin on abomasal emptying rate in suckling calves. | 2009 | Am. J. Vet. Res. | pmid:19335110 |
Wiles A and Woodward JM | Recent advances in the management of intestinal failure-associated liver disease. | 2009 | Curr Opin Clin Nutr Metab Care | pmid:19339882 |
Billal DS et al. | Loss of erythromycin resistance genes from strains of Streptococcus pyogenes that have developed resistance to levofloxacin. | 2009 | Diagn. Microbiol. Infect. Dis. | pmid:19345038 |
Graham JS et al. | A multi-centre dose-escalation and pharmacokinetic study of diflomotecan in patients with advanced malignancy. | 2009 | Cancer Chemother. Pharmacol. | pmid:18654747 |
Stang EM and White MC | Total synthesis and study of 6-deoxyerythronolide B by late-stage C-H oxidation. | 2009 | Nat Chem | pmid:21378935 |
Du-Cuny L et al. | Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. | 2009 | Bioorg. Med. Chem. | pmid:19734051 |
Kelmer G and Hayes ME | Regional limb perfusion with erythromycin for treatment of septic physitis and arthritis caused by Rhodococcus equi. | 2009 | Vet. Rec. | pmid:19734562 |
May T et al. | Induction of multidrug resistance mechanism in Escherichia coli biofilms by interplay between tetracycline and ampicillin resistance genes. | 2009 | Antimicrob. Agents Chemother. | pmid:19721076 |
Ghosh P et al. | Modeling a macrocyclic bis[spirodiepoxide] strategy to erythronolide A. | 2009 | Org. Lett. | pmid:19725523 |
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Nam HM et al. | Antimicrobial resistance of streptococci isolated from mastitic bovine milk samples in Korea. | 2009 | J. Vet. Diagn. Invest. | pmid:19737768 |
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Varaldo PE et al. | Genetic elements responsible for erythromycin resistance in streptococci. | 2009 | Antimicrob. Agents Chemother. | pmid:19001115 |
Xu P et al. | Synthesis and antibacterial activity of 11,12-carbamate-3-O-acyl erythromycin derivatives. | 2009 | J Asian Nat Prod Res | pmid:20183250 |
Tanaka H et al. | Problems associated with prophylactic use of erythromycin in 1566 staff to prevent hospital infection during the outbreak of pertussis. | 2009 | J Clin Pharm Ther | pmid:20175806 |
Azizia M and Ahmed M | Association between cerebral palsy and erythromycin. | 2009 | Lancet | pmid:19121711 |
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Morgenstern K et al. | In vitro susceptibility of Borrelia spielmanii to antimicrobial agents commonly used for treatment of Lyme disease. | 2009 | Antimicrob. Agents Chemother. | pmid:19075048 |
Jakeman DL et al. | Antimicrobial activities of jadomycin B and structurally related analogues. | 2009 | Antimicrob. Agents Chemother. | pmid:19075054 |
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Jiang X et al. | Synthesis and evaluation of antibacterial activities of andrographolide analogues. | 2009 | Eur J Med Chem | pmid:19152987 |
Borg MA et al. | Prevalence of penicillin and erythromycin resistance among invasive Streptococcus pneumoniae isolates reported by laboratories in the southern and eastern Mediterranean region. | 2009 | Clin. Microbiol. Infect. | pmid:19154490 |
Pannicke U et al. | Reticular dysgenesis (aleukocytosis) is caused by mutations in the gene encoding mitochondrial adenylate kinase 2. | 2009 | Nat. Genet. | pmid:19043417 |
Fritsche TR et al. | Antimicrobial activity of prulifloxacin tested against a worldwide collection of gastroenteritis-producing pathogens, including those causing traveler's diarrhea. | 2009 | Antimicrob. Agents Chemother. | pmid:19114678 |
Henry F et al. | [Image of the month. Combined chancre, a soft chancroid and a syphilitic chancre]. | 2009 | Rev Med Liege | pmid:19514534 |
Wolff KA et al. | Protein kinase G is required for intrinsic antibiotic resistance in mycobacteria. | 2009 | Antimicrob. Agents Chemother. | pmid:19528288 |
House B et al. | Acid-stress-induced changes in enterohaemorrhagic Escherichia coli O157 : H7 virulence. | 2009 | Microbiology (Reading, Engl.) | pmid:19497950 |
Wu L et al. | In vitro effects of erythromycin on RANKL and nuclear factor-kappa B by human TNF-alpha stimulated Jurkat cells. | 2009 | Int. Immunopharmacol. | pmid:19500694 |
Takagi Y et al. | Erythromycin-induced CXCR4 expression on microvascular endothelial cells. | 2009 | Am. J. Physiol. Lung Cell Mol. Physiol. | pmid:19502290 |