MeSH term | MeSH ID | Detail |
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Hoarseness | D006685 | 2 associated lipids |
Occupational Injuries | D060051 | 1 associated lipids |
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Kabir AR et al. | Management of bronchiolitis without antibiotics: a multicentre randomized control trial in Bangladesh. | 2009 | Acta Paediatr. | pmid:19572992 |
Ung D et al. | Metabolic interactions between prokinetic agents domperidone and erythromycin: an in vitro analysis. | 2009 | Xenobiotica | pmid:19575604 |
Pinheiro S et al. | Prevalence and mechanisms of erythromycin resistance in Streptococcus agalactiae from healthy pregnant women. | 2009 | Microb. Drug Resist. | pmid:19432524 |
Su JH et al. | Ferrous iron-binding protein Omb of Salmonella enterica serovar Choleraesuis promotes resistance to hydrophobic antibiotics and contributes to its virulence. | 2009 | Microbiology (Reading, Engl.) | pmid:19389759 |
Tateda K | [New Actions of macrolides. General topics. Summary of discussion. (2)]. | 2009 | Jpn J Antibiot | pmid:22454853 |
Yamaya M | [Effects of macrolides in preventing influenza and airway inflammation]. | 2009 | Jpn J Antibiot | pmid:22454856 |
Lin HT et al. | MacB ABC transporter is a dimer whose ATPase activity and macrolide-binding capacity are regulated by the membrane fusion protein MacA. | 2009 | J. Biol. Chem. | pmid:18955484 |
Paasche SR | Rhodococcus equi infection in a surgical wound. | 2009 | Clin Lab Sci | pmid:19827407 |
Beliaev AM et al. | Erythromycin-induced postprandial biliary colic. | 2009 | N. Z. Med. J. | pmid:19829393 |
de la Pedrosa EG et al. | High clonal diversity in erythromycin-resistant Streptococcus pneumoniae invasive isolates in Madrid, Spain (2000-07). | 2009 | J. Antimicrob. Chemother. | pmid:19837717 |
Huang SX et al. | Erythronolides H and I, new erythromycin congeners from a new halophilic actinomycete Actinopolyspora sp. YIM90600. | 2009 | Org. Lett. | pmid:19228040 |
Muri D and Carreira EM | Stereoselective synthesis of erythronolide A via nitrile oxide cycloadditions and related studies. | 2009 | J. Org. Chem. | pmid:19839571 |
Cooper WO et al. | Antibiotics potentially used in response to bioterrorism and the risk of major congenital malformations. | 2009 | Paediatr Perinat Epidemiol | pmid:19228311 |
Udayakumar D and Sanaullah M | Campylobacter cholecystitis. | 2009 | Int J Med Sci | pmid:19960123 |
Wehmeier C et al. | Site-directed mutagenesis reveals amino acid residues in the Escherichia coli RND efflux pump AcrB that confer macrolide resistance. | 2009 | Antimicrob. Agents Chemother. | pmid:18936189 |
Jeters RT et al. | Antibiotic resistance genes in the vaginal microbiota of primates not normally exposed to antibiotics. | 2009 | Microb. Drug Resist. | pmid:19857138 |
Picazo JJ | Management of antibiotic-resistant Streptococcus pneumoniae infections and the use of pneumococcal conjugate vaccines. | 2009 | Clin. Microbiol. Infect. | pmid:19366362 |
Sanger GJ et al. | GSK962040: a small molecule, selective motilin receptor agonist, effective as a stimulant of human and rabbit gastrointestinal motility. | 2009 | Neurogastroenterol. Motil. | pmid:19374732 |
Lahu G et al. | Effect of repeated dose of erythromycin on the pharmacokinetics of roflumilast and roflumilast N-oxide. | 2009 | Int J Clin Pharmacol Ther | pmid:19356389 |
Murayama SY et al. | Capsular type and antibiotic resistance in Streptococcus agalactiae isolates from patients, ranging from newborns to the elderly, with invasive infections. | 2009 | Antimicrob. Agents Chemother. | pmid:19332682 |
Arhin FF et al. | Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates. | 2009 | Antimicrob. Agents Chemother. | pmid:19738026 |
Hao H et al. | 23S rRNA mutation A2074C conferring high-level macrolide resistance and fitness cost in Campylobacter jejuni. | 2009 | Microb. Drug Resist. | pmid:19857128 |
Tanaka H et al. | Problems associated with prophylactic use of erythromycin in 1566 staff to prevent hospital infection during the outbreak of pertussis. | 2009 | J Clin Pharm Ther | pmid:20175806 |
Bae S and Lee K | Distribution of capsular serotypes and macrolide resistance mechanisms among macrolide-resistant Streptococcus pneumoniae isolates in Korea. | 2009 | Diagn. Microbiol. Infect. Dis. | pmid:19097840 |
Del Grosso M et al. | New composite genetic element of the Tn916 family with dual macrolide resistance genes in a Streptococcus pneumoniae isolate belonging to clonal complex 271. | 2009 | Antimicrob. Agents Chemother. | pmid:19104015 |
Jiang X et al. | Synthesis and evaluation of antibacterial activities of andrographolide analogues. | 2009 | Eur J Med Chem | pmid:19152987 |
Borg MA et al. | Prevalence of penicillin and erythromycin resistance among invasive Streptococcus pneumoniae isolates reported by laboratories in the southern and eastern Mediterranean region. | 2009 | Clin. Microbiol. Infect. | pmid:19154490 |
Ozaki K et al. | Effects of mitemcinal (GM-611), an orally active erythromycin-derived prokinetic agent, on delayed gastric emptying and postprandial glucose in a new minipig model of diabetes. | 2008 Sep-Oct | J. Diabetes Complicat. | pmid:18413164 |
Rassi H and Ghasemi SF | Production of novel chemotherapeutic drugs by Streptomycetes. | 2008 Oct-Dec | Lik. Sprava | pmid:19663015 |
Pomero G et al. | [Neonatal group B Streptococcus infection: an integrated approach (of clinical pathologists, gynecologists, midwives, pediatricians-neonatologists) of the functional area of Cuneo (Italy)]. | 2008 Nov-Dec | Pediatr Med Chir | pmid:19431950 |
Vlieghe ER et al. | Trends of norfloxacin and erythromycin resistance of Campylobacter jejuni/Campylobacter coli isolates recovered from international travelers, 1994 to 2006. | 2008 Nov-Dec | J Travel Med | pmid:19090796 |
Van Der Beek MT et al. | Mycobacterium chelonae keratitis in a patient with Sjögren's syndrome. | 2008 Mar-Apr | Eur J Ophthalmol | pmid:18320526 |
Angel MR et al. | Prevalence of inducible clindamycin resistance in gram positive organisms in a tertiary care centre. | 2008 Jul-Sep | Indian J Med Microbiol | pmid:18695329 |
Farrant P et al. | Is erythromycin an effective treatment for chronic bullous disease of childhood? A national survey of members of the British Society for Paediatric Dermatology. | 2008 Jul-Aug | Pediatr Dermatol | pmid:18789096 |
MacLaren R et al. | Erythromycin vs metoclopramide for facilitating gastric emptying and tolerance to intragastric nutrition in critically ill patients. | 2008 Jul-Aug | JPEN J Parenter Enteral Nutr | pmid:18596312 |
Bitarães EL et al. | Compliance with antibiotic prophylaxis in children with sickle cell anemia: a prospective study. | 2008 Jul-Aug | J Pediatr (Rio J) | pmid:18688558 |
Landzinski J et al. | Gastric motility function in critically ill patients tolerant vs intolerant to gastric nutrition. | 2008 Jan-Feb | JPEN J Parenter Enteral Nutr | pmid:18165446 |
Nouri M et al. | Effect of erythromycin and gentamicin on abomasal emptying rate in suckling calves. | 2008 Jan-Feb | J. Vet. Intern. Med. | pmid:18289310 |
Winters M et al. | Epidemiology of invasive pneumococcal disease in BC during the introduction of conjugated pneumococcal vaccine. | 2008 Jan-Feb | Can J Public Health | pmid:18435393 |
Yamamoto S et al. | Gamma-butyrolactone-dependent expression of the Streptomyces antibiotic regulatory protein gene srrY plays a central role in the regulatory cascade leading to lankacidin and lankamycin production in Streptomyces rochei. | 2008 | J. Bacteriol. | pmid:18083808 |
Montagnani F et al. | Pneumococcal disease in a paediatric population in a hospital of central Italy: a clinical and microbiological case series from 1992 to 2006. | 2008 | J. Infect. | pmid:18222005 |
Chen Y et al. | Genetic modulation of the overexpression of tailoring genes eryK and eryG leading to the improvement of erythromycin A purity and production in Saccharopolyspora erythraea fermentation. | 2008 | Appl. Environ. Microbiol. | pmid:18223111 |
Buiter HJ et al. | Erythromycin precipitation in vena femoralis: investigation of crystals found in postmortem material of an intensive care unit patient. | 2008 | Ther Drug Monit | pmid:18223476 |
Ressner RA et al. | Activity of the Diaminopyrimidine AR-709 against recently collected multidrug-resistant isolates of invasive Streptococcus pneumoniae from North America. | 2008 | Antimicrob. Agents Chemother. | pmid:18180346 |
Sader HS et al. | Antimicrobial activities of Ceftaroline and ME1036 tested against clinical strains of community-acquired methicillin-resistant Staphylococcus aureus. | 2008 | Antimicrob. Agents Chemother. | pmid:18180353 |
Woodbury RL et al. | Plasmid-Borne erm(T) from invasive, macrolide-resistant Streptococcus pyogenes strains. | 2008 | Antimicrob. Agents Chemother. | pmid:18180360 |
Roy SK et al. | Zinc supplementation in children with cholera in Bangladesh: randomised controlled trial. | 2008 | BMJ | pmid:18184631 |
Kim BJ et al. | Generation of nicotinic acid adenine dinucleotide phosphate and cyclic ADP-ribose by glucagon-like peptide-1 evokes Ca2+ signal that is essential for insulin secretion in mouse pancreatic islets. | 2008 | Diabetes | pmid:18184929 |
Isoherranen N et al. | The influence of CYP3A5 expression on the extent of hepatic CYP3A inhibition is substrate-dependent: an in vitro-in vivo evaluation. | 2008 | Drug Metab. Dispos. | pmid:17954524 |
Starner TD et al. | Subinhibitory concentrations of azithromycin decrease nontypeable Haemophilus influenzae biofilm formation and Diminish established biofilms. | 2008 | Antimicrob. Agents Chemother. | pmid:17954687 |
Morozumi M et al. | Increased macrolide resistance of Mycoplasma pneumoniae in pediatric patients with community-acquired pneumonia. | 2008 | Antimicrob. Agents Chemother. | pmid:17954691 |
Dias R and Caniça M | Trends in resistance to penicillin and erythromycin of invasive pneumococci in Portugal. | 2008 | Epidemiol. Infect. | pmid:17697443 |
Nguyen NQ et al. | Risk of Clostridium difficile diarrhoea in critically ill patients treated with erythromycin-based prokinetic therapy for feed intolerance. | 2008 | Intensive Care Med | pmid:17701160 |
Gai Y et al. | Synthesis of 3,6-bicyclolides: a novel class of macrolide antibiotics. | 2008 | Bioorg. Med. Chem. Lett. | pmid:18996692 |
Kenyon S et al. | Childhood outcomes after prescription of antibiotics to pregnant women with preterm rupture of the membranes: 7-year follow-up of the ORACLE I trial. | 2008 | Lancet | pmid:18804274 |
Russell AR and Steer PJ | Antibiotics in preterm labour--the ORACLE speaks. | 2008 | Lancet | pmid:18804275 |
Kenyon S et al. | Childhood outcomes after prescription of antibiotics to pregnant women with spontaneous preterm labour: 7-year follow-up of the ORACLE II trial. | 2008 | Lancet | pmid:18804276 |
Bavikar SN et al. | Synthesis of chimeric tetrapeptide-linked cholic acid derivatives: impending synergistic agents. | 2008 | Bioorg. Med. Chem. Lett. | pmid:18805690 |
Saijo T et al. | A case of Legionella pneumophila pneumonia followed by invasive aspergillosis. | 2008 | Jpn. J. Infect. Dis. | pmid:18806346 |
Hyo Y et al. | Characteristic cell wall ultrastructure of a macrolide-resistant Staphylococcus capitis strain isolated from a patient with chronic sinusitis. | 2008 | Med Mol Morphol | pmid:18807142 |
Lambertsen L et al. | Erythromycin resistance caused by erm(A) subclass erm(TR) in a Danish invasive pneumococcal isolate: are erm(A) pneumococcal isolates overlooked? | 2008 | Scand. J. Infect. Dis. | pmid:18584554 |
Vaara M et al. | Novel polymyxin derivatives carrying only three positive charges are effective antibacterial agents. | 2008 | Antimicrob. Agents Chemother. | pmid:18591267 |
Amsler KM et al. | In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections. | 2008 | Antimicrob. Agents Chemother. | pmid:18591277 |
Adams NP and Congelton J | Diffuse panbronchiolitis. | 2008 | Eur. Respir. J. | pmid:18591343 |
Brauteset LV et al. | [Invasive pneumoccal disease in children in Oslo 1998-2004]. | 2008 | Tidsskr. Nor. Laegeforen. | pmid:18552897 |
Yamazaki T et al. | The intracellular accumulation of phagocytic and epithelial cells and the inhibitory effect on Chlamydophila (Chlamydia) pneumoniae of telithromycin and comparator antimicrobials. | 2008 | J Chemother | pmid:18676220 |
Yang Y | [Mechanism and clinical application of erythromycin as a gastrointestinal prokinetic agent in children]. | 2008 | Zhongguo Dang Dai Er Ke Za Zhi | pmid:18289489 |
Inoue D et al. | Erythromycin attenuates MUC5AC synthesis and secretion in cultured human tracheal cells infected with RV14. | 2008 | Respirology | pmid:18339018 |
Onoma M et al. | Mitemcinal (GM-611), an orally active motilin receptor agonist, improves delayed gastric emptying in a canine model of diabetic gastroparesis. | 2008 | Clin. Exp. Pharmacol. Physiol. | pmid:18346169 |
Haghedooren E et al. | Comparison of two column characterisation systems based on pharmaceutical applications. | 2008 | J Chromatogr A | pmid:18295221 |
Liu YQ et al. | Quantitative determination of erythromycylamine in human plasma by liquid chromatography-mass spectrometry and its application in a bioequivalence study of dirithromycin. | 2008 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:18296129 |
Komuro I et al. | Erythromycin derivatives inhibit HIV-1 replication in macrophages through modulation of MAPK activity to induce small isoforms of C/EBPbeta. | 2008 | Proc. Natl. Acad. Sci. U.S.A. | pmid:18719105 |
Yang F et al. | Antimicrobial susceptibility and molecular epidemiology of Streptococcus pneumoniae isolated from Shanghai, China. | 2008 | Int. J. Antimicrob. Agents | pmid:18723327 |
Seemungal TA et al. | Long-term erythromycin therapy is associated with decreased chronic obstructive pulmonary disease exacerbations. | 2008 | Am. J. Respir. Crit. Care Med. | pmid:18723437 |
Mally M and Cornelis GR | Genetic tools for studying Capnocytophaga canimorsus. | 2008 | Appl. Environ. Microbiol. | pmid:18723653 |
Fernández-Roblas R et al. | In vitro activities of tigecycline and 10 other antimicrobials against nonpigmented rapidly growing mycobacteria. | 2008 | Antimicrob. Agents Chemother. | pmid:18725441 |
Fenoll A et al. | In vitro activity of ceftaroline against Streptococcus pneumoniae isolates exhibiting resistance to penicillin, amoxicillin, and cefotaxime. | 2008 | Antimicrob. Agents Chemother. | pmid:18725443 |
Korolkiewicz RP and Kuziemski K | Use of erythromycin in prevention or treatment of postoperative ileus. | 2008 | Urology | pmid:18400282 |
Luppens SB et al. | Effect of Veillonella parvula on the antimicrobial resistance and gene expression of Streptococcus mutans grown in a dual-species biofilm. | 2008 | Oral Microbiol. Immunol. | pmid:18402603 |
Min YH et al. | Molecular analysis of constitutive mutations in ermB and ermA selected in vitro from inducibly MLSB-resistant enterococci. | 2008 | Arch. Pharm. Res. | pmid:18409053 |
Besier S et al. | The thymidine-dependent small-colony-variant phenotype is associated with hypermutability and antibiotic resistance in clinical Staphylococcus aureus isolates. | 2008 | Antimicrob. Agents Chemother. | pmid:18378706 |
Reinert RR et al. | Mechanisms of macrolide resistance among Streptococcus pneumoniae isolates from Russia. | 2008 | Antimicrob. Agents Chemother. | pmid:18378707 |
Schreiber F and Szewzyk U | Environmentally relevant concentrations of pharmaceuticals influence the initial adhesion of bacteria. | 2008 | Aquat. Toxicol. | pmid:18359104 |
de la Pedrosa EG et al. | Polyclonal population structure of Streptococcus pneumoniae isolates in Spain carrying mef and mef plus erm(B). | 2008 | Antimicrob. Agents Chemother. | pmid:18362188 |
Betancor L et al. | Improved catalytic activity of a purified multienzyme from a modular polyketide synthase after coexpression with Streptomyces chaperonins in Escherichia coli. | 2008 | Chembiochem | pmid:19021139 |
Kunisaki KM and Niewoehner DE | Antibiotic prophylaxis for chronic obstructive pulmonary disease: resurrecting an old idea. | 2008 | Am. J. Respir. Crit. Care Med. | pmid:19023036 |
Janapatla RP et al. | The prevalence of erythromycin resistance in group B streptococcal isolates at a University Hospital in Taiwan. | 2008 | Microb. Drug Resist. | pmid:19025386 |
Harita S et al. | Effect of long-term and low-dose administration of erythromycin on proliferation of T lymphocytes stimulated with mitogens. | 2008 | J Chemother | pmid:19028624 |
Rhodes LD et al. | Characterization of Renibacterium salmoninarum with reduced susceptibility to macrolide antibiotics by a standardized antibiotic susceptibility test. | 2008 | Dis. Aquat. Org. | pmid:18814542 |
Moore SD and Sauer RT | Revisiting the mechanism of macrolide-antibiotic resistance mediated by ribosomal protein L22. | 2008 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19015512 |
Xu P et al. | Synthesis and antibacterial activity of 4''-O-heteroarylcarbamoyl derivatives of macrolide. | 2008 | Bioorg. Med. Chem. Lett. | pmid:18815034 |
Yao SM et al. | Antimicrobial susceptibility testing of Bordetella pertussis in Taiwan prompted by a case of pertussis in a paediatric patient. | 2008 | J. Med. Microbiol. | pmid:19018032 |
Lewis CA et al. | Catalytic site-selective synthesis and evaluation of a series of erythromycin analogs. | 2008 | Bioorg. Med. Chem. Lett. | pmid:18819795 |
Fenoll A et al. | Has the licensing of respiratory quinolones for adults and the 7-valent pneumococcal conjugate vaccine (PCV-7) for children had herd effects with respect to antimicrobial non-susceptibility in invasive Streptococcus pneumoniae? | 2008 | J. Antimicrob. Chemother. | pmid:18819966 |
Westaway SM et al. | The discovery of biaryl carboxamides as novel small molecule agonists of the motilin receptor. | 2008 | Bioorg. Med. Chem. Lett. | pmid:19006669 |
Priscila G et al. | Expression of the bacterial hemoglobin gene from Vitreoscilla stercoraria increases rifamycin B production in Amycolatopsis mediterranei. | 2008 | J. Biosci. Bioeng. | pmid:19111646 |
Gan M et al. | Glycosides from the root of Iodes cirrhosa. | 2008 | J. Nat. Prod. | pmid:18327912 |
Bartels AL et al. | Decreased blood-brain barrier P-glycoprotein function in the progression of Parkinson's disease, PSP and MSA. | 2008 | J Neural Transm (Vienna) | pmid:18265929 |
Zhang M et al. | Recombinant anti-vascular endothelial growth factor fusion protein efficiently suppresses choridal neovasularization in monkeys. | 2008 | Mol. Vis. | pmid:18246030 |
Li X et al. | Fluorinated porphyrin tweezer: a powerful reporter of absolute configuration for erythro and threo diols, amino alcohols, and diamines. | 2008 | J. Am. Chem. Soc. | pmid:18211067 |