erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

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Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hoarseness D006685 2 associated lipids
Occupational Injuries D060051 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Zou X et al. Real-time fluid dynamics investigation and physiological response for erythromycin fermentation scale-up from 50 L to 132 m3 fermenter. 2012 Bioprocess Biosyst Eng pmid:22139481
Fischer H et al. In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets. 2012 J. Med. Chem. pmid:22122484
Perić M et al. Antimalarial activity of 9a-N substituted 15-membered azalides with improved in vitro and in vivo activity over azithromycin. 2012 J. Med. Chem. pmid:22148880
Reil M et al. Seasonality of Clostridium difficile infections in Southern Germany. 2012 Epidemiol. Infect. pmid:22152928
Osman KM et al. Antimicrobial susceptibility and molecular typing of multiple Chlamydiaceae species isolated from genital infection of women in Egypt. 2012 Microb. Drug Resist. pmid:22455539
Marlow N et al. Characteristics of children with cerebral palsy in the ORACLE children study. 2012 Dev Med Child Neurol pmid:22458348
Lialikov SA et al. [Monitoring of side effects and estimation of cycloferon efficacy in treatment of children with frequent and prolonged diseases]. 2012 Antibiot. Khimioter. pmid:23700934
Teodoro CR et al. Characterization of MLS(b) resistance among Staphylococcus aureus and Staphylococcus epidermidis isolates carrying different SCCmec types. 2012 Microbiol. Immunol. pmid:22672011
Laurens C et al. Clinical and antimicrobial susceptibility data of 140 Streptococcus pseudopneumoniae isolates in France. 2012 Antimicrob. Agents Chemother. pmid:22644030
Thumu SC and Halami PM Presence of erythromycin and tetracycline resistance genes in lactic acid bacteria from fermented foods of Indian origin. 2012 Antonie Van Leeuwenhoek pmid:22644346
Chuang CC et al. Staphylococcus aureus ocular infection: methicillin-resistance, clinical features, and antibiotic susceptibilities. 2012 PLoS ONE pmid:22880135
Block SL Etiologic and therapeutic pitfalls of newborn conjunctivitis. 2012 Pediatr Ann pmid:22881420
Nelson CG and Burke TR Samarium iodide-mediated Reformatsky reactions for the stereoselective preparation of β-hydroxy-γ-amino acids: synthesis of isostatine and dolaisoleucine. 2012 J. Org. Chem. pmid:22136325
Zhou X et al. Marthiapeptide A, an anti-infective and cytotoxic polythiazole cyclopeptide from a 60 L scale fermentation of the deep sea-derived Marinactinospora thermotolerans SCSIO 00652. 2012 J. Nat. Prod. pmid:23215246
Rocco L et al. Micronucleus test and comet assay for the evaluation of zebrafish genomic damage induced by erythromycin and lincomycin. 2012 Environ. Toxicol. pmid:21384490
Smith EM et al. In vitro inhibition of cytochrome P450-mediated reactions by gemfibrozil, erythromycin, ciprofloxacin and fluoxetine in fish liver microsomes. 2012 Aquat. Toxicol. pmid:22000335
Lu S and Zgurskaya HI Role of ATP binding and hydrolysis in assembly of MacAB-TolC macrolide transporter. 2012 Mol. Microbiol. pmid:23057817
Parhi A et al. Antibacterial activity of substituted dibenzo[a,g]quinolizin-7-ium derivatives. 2012 Bioorg. Med. Chem. Lett. pmid:23058886
Lancaster CS et al. OATP1B1 polymorphism as a determinant of erythromycin disposition. 2012 Clin. Pharmacol. Ther. pmid:22990751
Rubio-López V et al. Molecular epidemiology, antimicrobial susceptibilities and resistance mechanisms of Streptococcus pyogenes isolates resistant to erythromycin and tetracycline in Spain (1994-2006). 2012 BMC Microbiol. pmid:22998619
Henningsen E and Bygum A Budesonide-induced periorificial dermatitis presenting as chalazion and blepharitis. 2011 Sep-Oct Pediatr Dermatol pmid:21895758
Ezhova NM et al. [Molecularly imprinted hydrophilic polymer sorbents for selective sorption of erythromycin]. 2011 Nov-Dec Prikl. Biokhim. Mikrobiol. pmid:22288199
Nielsen EI et al. Predicting in vitro antibacterial efficacy across experimental designs with a semimechanistic pharmacokinetic-pharmacodynamic model. 2011 Antimicrob. Agents Chemother. pmid:21282424
Belousoff MJ et al. Crystal structure of the synergistic antibiotic pair, lankamycin and lankacidin, in complex with the large ribosomal subunit. 2011 Proc. Natl. Acad. Sci. U.S.A. pmid:21282615
Yuan H et al. [The effect of erythromycin on transforming growth factor-β(1) and secretory leukocyte proteinase inhibitor in a rat model of chronic obstructive pulmonary disease]. 2011 Zhonghua Jie He He Hu Xi Za Zhi pmid:22041779
Spigaglia P et al. Surface layer protein A variant of Clostridium difficile PCR-ribotype 027. 2011 Emerging Infect. Dis. pmid:21291621
Huppertz A et al. Evaluation of possible drug-drug interaction between gadoxetic acid and erythromycin as an inhibitor of organic anion transporting peptides (OATP). 2011 J Magn Reson Imaging pmid:21274983
Watanabe I et al. Combined effect of disopyramide and erythromycin on ventricular repolarization in dogs with complete atrioventricular block. 2011 Int Heart J pmid:22188715
Rodríguez C et al. [Resistance phenotypes and genotypes of Streptococcus pyogenes clinical isolates in Chile over a 10-year period]. 2011 Rev Med Chil pmid:22215392
Tazi A et al. Invasive group B streptococcal infections in adults, France (2007-2010). 2011 Clin. Microbiol. Infect. pmid:21883671
Fenoll A et al. Increase in serotype 19A prevalence and amoxicillin non-susceptibility among paediatric Streptococcus pneumoniae isolates from middle ear fluid in a passive laboratory-based surveillance in Spain, 1997-2009. 2011 BMC Infect. Dis. pmid:21910891
Maezono H et al. Antibiofilm effects of azithromycin and erythromycin on Porphyromonas gingivalis. 2011 Antimicrob. Agents Chemother. pmid:21911560
Sigaroudinia MO and Quayle AR Oral erythromycin relieves dysphagia in a patient with known oesophageal hypomotility disorder who has had a Nissen's fundoplication. 2011 Surgeon pmid:21550524
Lehtopolku M et al. Ribosomal mutations as the main cause of macrolide resistance in Campylobacter jejuni and Campylobacter coli. 2011 Antimicrob. Agents Chemother. pmid:21911571
Szary NM et al. Erythromycin prior to endoscopy in acute upper gastrointestinal bleeding: a meta-analysis. 2011 Scand. J. Gastroenterol. pmid:21561232
Tanamachi C et al. [A case of Desulfovibrio desulfuricans cultured from blood in Japan]. 2011 Rinsho Byori pmid:21706860
Mikura S et al. Erythromycin prevents the pulmonary inflammation induced by exposure to cigarette smoke. 2011 Transl Res pmid:21708354
Richter SS et al. Activity of ceftaroline and epidemiologic trends in Staphylococcus aureus isolates collected from 43 medical centers in the United States in 2009. 2011 Antimicrob. Agents Chemother. pmid:21709080
Muruganathan G et al. Interaction study of moxifloxacin and lomefloxacin with co-administered drugs. 2011 Pak J Pharm Sci pmid:21715267
Panigaj M et al. Expression of prion protein in mouse erythroid progenitors and differentiating murine erythroleukemia cells. 2011 PLoS ONE pmid:21912705
Maragno AL et al. ISG15 modulates development of the erythroid lineage. 2011 PLoS ONE pmid:22022510
Kreft A et al. JAK2-V617F-mutated myeloproliferative neoplasms reveal different allele burden within hematopoietic cell lineages: a microdissection study of bone marrow trephine biopsies. 2011 Virchows Arch. pmid:22006129
Zaed AM and Sutherland A Total synthesis of clavaminol A, C and H. 2011 Org. Biomol. Chem. pmid:21879135
Taillon MP et al. Potentially new isobaric metabolite of fluvastatin observed by LC-MS/MS during incurred sample analysis. 2011 Bioanalysis pmid:21877892
Pignatello R et al. Amphiphilic erythromycin-lipoamino acid ion pairs: characterization and in vitro microbiological evaluation. 2011 AAPS PharmSciTech pmid:21479751
Keelan JA et al. Maternal-amniotic-fetal distribution of macrolide antibiotics following intravenous, intramuscular, and intraamniotic administration in late pregnant sheep. 2011 Am. J. Obstet. Gynecol. pmid:21481833
Fan C and He J Proliferation of antibiotic resistance genes in microbial consortia of sequencing batch reactors (SBRs) upon exposure to trace erythromycin or erythromycin-H2O. 2011 Water Res. pmid:21482429
Franke RM et al. Effect of ABCC2 (MRP2) transport function on erythromycin metabolism. 2011 Clin. Pharmacol. Ther. pmid:21451505
Li Y et al. Molecular characterization of erm(B)- and mef(E)-mediated erythromycin-resistant Streptococcus pneumoniae in China and complete DNA sequence of Tn2010. 2011 J. Appl. Microbiol. pmid:20961364
Vuppalanchi R et al. Drug-induced QT prolongation in cirrhotic patients with transjugular intrahepatic portosystemic shunt. 2011 J. Clin. Gastroenterol. pmid:20962670