erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Gas Gangrene D005738 1 associated lipids
Sebaceous Gland Diseases D012625 1 associated lipids
Atrioventricular Block D054537 1 associated lipids
Erysipelas D004886 1 associated lipids
Endocarditis, Subacute Bacterial D004698 1 associated lipids
Lacrimal Duct Obstruction D007767 1 associated lipids
Choanal Atresia D002754 1 associated lipids
Scarlet Fever D012541 1 associated lipids
Erythrasma D004894 1 associated lipids
Granuloma, Respiratory Tract D015769 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
Wald ER Sinusitis. 1998 Pediatr Ann pmid:9866138
Toyota K Pyloric opening and closure evaluated by means of strain gauge force transducers. 1998 J Smooth Muscle Res pmid:9866113
Delaforge M Importance of metabolism in pharmacological studies: possible in vitro predictability. 1998 Nucl. Med. Biol. pmid:9863553
Coulie B et al. Involvement of two different pathways in the motor effects of erythromycin on the gastric antrum in humans. 1998 Gut pmid:9863486
Unge J et al. The crystal structure of ribosomal protein L22 from Thermus thermophilus: insights into the mechanism of erythromycin resistance. 1998 Structure pmid:9862810
Weissman KJ et al. Evaluating precursor-directed biosynthesis towards novel erythromycins through in vitro studies on a bimodular polyketide synthase. 1998 Chem. Biol. pmid:9862800
Hsueh PR et al. Dissemination of high-level penicillin-, extended-spectrum cephalosporin-, and erythromycin-resistant Streptococcus pneumoniae clones in Taiwan. 1999 J. Clin. Microbiol. pmid:9854097
Roy SK et al. A randomized clinical trial to compare the efficacy of erythromycin, ampicillin and tetracycline for the treatment of cholera in children. 1998 Jul-Aug Trans. R. Soc. Trop. Med. Hyg. pmid:9850410
Yamazaki H and Shimada T Formation in vitro of an inhibitory cytochrome P450 x Fe2+-metabolite complex with roxithromycin and its decladinosyl, O-dealkyl and N-demethyl metabolites in rat liver microsomes. 1998 Xenobiotica pmid:9849646
Belkengren R and Sapala S Pediatric management problems. Left corneal abrasion. 1998 Jul-Aug Pediatr Nurs pmid:9849269
Barry AL et al. Susceptibility to RPR 106,972, quinupristin/dalfopristin and erythromycin among recent clinical isolates of enterococci, staphylococci and streptococci from North American medical centres. 1998 J. Antimicrob. Chemother. pmid:9848451
Soriano F et al. In-vitro antimicrobial activity of HMR 3004 (RU 64004) against erythromycin A-sensitive and -resistant Corynebacterium spp. isolated from clinical specimens. 1998 J. Antimicrob. Chemother. pmid:9848450
Johnson AP et al. In-vitro activity of sanfetrinem against isolates of Streptococcus pneumoniae and Staphylococcus aureus. 1998 J. Antimicrob. Chemother. pmid:9848449
Shadomy S et al. Josamycin and rosamicin: in vitro comparisons with erythromycin and clindamycin. 1976 Antimicrob. Agents Chemother. pmid:984811
Strausbaugh LJ et al. Comparative pharmacology of josamycin and erythromycin stearate. 1976 Antimicrob. Agents Chemother. pmid:984786
Santoro J et al. In vitro activity of josamycin and rosamicin against Bacteroides fragilis compared with clindamycin, erythromycin, and metronidazole. 1976 Antimicrob. Agents Chemother. pmid:984752
BÃ¥verud V et al. Clostridium difficile associated with acute colitis in mares when their foals are treated with erythromycin and rifampicin for Rhodococcus equi pneumonia. 1998 Equine Vet. J. pmid:9844966
Tan HH et al. Bacterial skin infections at a tertiary dermatological centre. 1998 Singapore Med J pmid:9844495
Drici MD et al. Cardiac actions of erythromycin: influence of female sex. 1998 JAMA pmid:9842954
Janković S et al. A case of syphilitic interstitial pulmonary fibrosis. 1998 Croat. Med. J. pmid:9841951