erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Krokidis MG et al. | Insights into the mode of action of novel fluoroketolides, potent inhibitors of bacterial protein synthesis. | 2014 | Antimicrob. Agents Chemother. | pmid:24189263 |
Krishnappa LG et al. | Serological and molecular capsular typing, antibiotic susceptibility of Streptococcus pneumoniae isolates from invasive and non-invasive infections. | 2014 | Acta Microbiol Immunol Hung | pmid:24939685 |
Florindo C et al. | Epidemiological surveillance of colonising group B Streptococcus epidemiology in the Lisbon and Tagus Valley regions, Portugal (2005 to 2012): emergence of a new epidemic type IV/clonal complex 17 clone. | 2014 | Euro Surveill. | pmid:24957747 |
Ye C et al. | Correlation between AcrB trimer association affinity and efflux activity. | 2014 | Biochemistry | pmid:24854514 |
Pasquini L et al. | Occurrence of eight household micropollutants in urban wastewater and their fate in a wastewater treatment plant. Statistical evaluation. | 2014 | Sci. Total Environ. | pmid:24631609 |
Fröhlicher S et al. | Serotype distribution and antimicrobial susceptibility of group B streptococci in pregnant women: results from a Swiss tertiary centre. | 2014 | Swiss Med Wkly | pmid:24652673 |
Cai HL et al. | Quantitative analysis of erythromycylamine in human plasma by liquid chromatography-tandem mass spectrometry and its application in a bioequivalence study of dirithromycin enteric-coated tablets with a special focus on the fragmentation pattern and carryover effect. | 2014 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:24424301 |
Arenz S et al. | Drug sensing by the ribosome induces translational arrest via active site perturbation. | 2014 | Mol. Cell | pmid:25306253 |
Carls A et al. | Systemic exposure of topical erythromycin in comparison to oral administration and the effect on cytochrome P450 3A4 activity. | 2014 | Br J Clin Pharmacol | pmid:25139487 |
Compain F et al. | Molecular characterization of Streptococcus agalactiae isolates harboring small erm(T)-carrying plasmids. | 2014 | Antimicrob. Agents Chemother. | pmid:25136004 |
Wagner G et al. | [Childhood granulomatous periorificial dermatitis]. | 2014 | Hautarzt | pmid:25115983 |
Wang Z et al. | High prevalence of erythromycin-resistant Bordetella pertussis in Xi'an, China. | 2014 | Clin. Microbiol. Infect. | pmid:24816168 |
Allen LN | Mild meningococcaemia, pyrexia protocols and a problematic public health response. | 2014 | BMJ Case Rep | pmid:24811106 |
Mulatu G et al. | Prevalence of Shigella, Salmonella and Campylobacter species and their susceptibility patters among under five children with diarrhea in Hawassa town, south Ethiopia. | 2014 | Ethiop J Health Sci | pmid:24795510 |
Ren WP et al. | Effect of erythromycin-doped calcium polyphosphate scaffold composite in a mouse pouch infection model. | 2014 | J. Biomed. Mater. Res. Part B Appl. Biomater. | pmid:24347324 |
Brenciani A et al. | Genetic determinants and elements associated with antibiotic resistance in viridans group streptococci. | 2014 | J. Antimicrob. Chemother. | pmid:24343896 |
Lu WC et al. | Erythromycin pretreatment induces tolerance against focal cerebral ischemia through up-regulation of nNOS but not down-regulation of HIF-1α in rats. | 2014 | Neurol. Sci. | pmid:24277204 |
Kim S and Muthusamy VR | Prophylactic erythromycin in acute upper gastrointestinal bleeding: moving forward in improving endoscopic efficacy. | 2013 Sep-Oct | Saudi J Gastroenterol | pmid:24045591 |
Theivanayagam S et al. | Administration of erythromycin before endoscopy in upper gastrointestinal bleeding: a meta-analysis of randomized controlled trials. | 2013 Sep-Oct | Saudi J Gastroenterol | pmid:24045593 |
Manchia M et al. | Repeated erythromycin/codeine-induced psychotic mania. | 2013 Sep-Oct | Clin Neuropharmacol | pmid:24045612 |
De Alwis HG et al. | Determination of erythromycin in medicated salmonid fish feed by liquid chromatography and UV spectroscopy. | 2013 Nov-Dec | J AOAC Int | pmid:24645499 |
Zou X et al. | Biochemical parameters of Saccharopolyspora erythraea during feeding ammonium sulphate in erythromycin biosynthesis phase. | 2013 Mar-Apr | Prikl. Biokhim. Mikrobiol. | pmid:23795479 |
Jiang M et al. | Improved heterologous erythromycin A production through expression plasmid re-design. | 2013 Jul-Aug | Biotechnol. Prog. | pmid:23804312 |
Lynch M et al. | Bullae of the hands, feet, and perioral area in a 3-month-old infant. Bullous pemphigoid. | 2013 Jan-Feb | Pediatr Dermatol | pmid:23316718 |
Litvinchuk AV et al. | Mitochondrially-encoded protein Var1 promotes loss of respiratory function in Saccharomyces cerevisiae under stressful conditions. | 2013 Apr-May | Eur. J. Cell Biol. | pmid:23523087 |
Kuwahara T et al. | Clinical characteristics and management of periesophageal vagal nerve injury complicating left atrial ablation of atrial fibrillation: lessons from eleven cases. | 2013 | J. Cardiovasc. Electrophysiol. | pmid:23551640 |
Lozada LE et al. | Development of pyloric stenosis after a 4-day course of oral erythromycin. | 2013 | Pediatr Emerg Care | pmid:23558266 |
Cuello-GarcÃa CA et al. | Treating BCG-induced disease in children. | 2013 | Cochrane Database Syst Rev | pmid:23440826 |
Jersild Jespersen M et al. | [Sparse effect of long-term treatment with macrolides in patients with chronic obstructive pulmonary disease]. | 2013 | Ugeskr. Laeg. | pmid:23462037 |
Jiang M and Pfeifer BA | Metabolic and pathway engineering to influence native and altered erythromycin production through E. coli. | 2013 | Metab. Eng. | pmid:23747605 |
Goh S et al. | Phage Ï•C2 mediates transduction of Tn6215, encoding erythromycin resistance, between Clostridium difficile strains. | 2013 | MBio | pmid:24255122 |
Horácio AN et al. | The majority of adult pneumococcal invasive infections in Portugal are still potentially vaccine preventable in spite of significant declines of serotypes 1 and 5. | 2013 | PLoS ONE | pmid:24066064 |
Guo L et al. | Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model. | 2013 | Toxicol. Sci. | pmid:24052561 |
Li YY et al. | Systems perspectives on erythromycin biosynthesis by comparative genomic and transcriptomic analyses of S. erythraea E3 and NRRL23338 strains. | 2013 | BMC Genomics | pmid:23902230 |
Cai G et al. | Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. | 2013 | J. Nat. Prod. | pmid:24224794 |
Ong SJ et al. | Staphylococcus aureus keratitis: a review of hospital cases. | 2013 | PLoS ONE | pmid:24244625 |
Fang J et al. | Dissecting the function of a protruding loop in AcrB trimerization. | 2013 | J. Biomol. Struct. Dyn. | pmid:22877148 |
Opdam FL et al. | Breath tests to phenotype drug disposition in oncology. | 2013 | Clin Pharmacokinet | pmid:23868281 |
Tsujimoto M et al. | Effects of decreased vitamin D and accumulated uremic toxin on human CYP3A4 activity in patients with end-stage renal disease. | 2013 | Toxins (Basel) | pmid:23965431 |
Lee A | Gastroparesis: what is the current state-of-the-art for evaluation and medical management? What are the results? | 2013 | J. Gastrointest. Surg. | pmid:23801519 |
Liu ZX et al. | [Inhibition of methanogenium by erythromycin and its domestation]. | 2013 | Huan Jing Ke Xue | pmid:23798140 |
Pasquini L et al. | Impact of certain household micropollutants on bacterial behavior. Toxicity tests/study of extracellular polymeric substances in sludge. | 2013 | Sci. Total Environ. | pmid:23827359 |
Malinka W et al. | Synthesis of novel isothiazolopyridines and their in vitro evaluation against Mycobacterium and Propionibacterium acnes. | 2013 | Bioorg. Med. Chem. | pmid:23850103 |
Wittwer MB et al. | Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling. | 2013 | J. Med. Chem. | pmid:23241029 |
Haruna M et al. | Prevalence and antimicrobial resistance of Campylobacter isolates from beef cattle and pigs in Japan. | 2013 | J. Vet. Med. Sci. | pmid:23220905 |
Javid FA et al. | Anti-emetic and emetic effects of erythromycin in Suncus murinus: role of vagal nerve activation, gastric motility stimulation and motilin receptors. | 2013 | Eur. J. Pharmacol. | pmid:23201066 |
Goodman CD et al. | Chemobiosynthesis of new antimalarial macrolides. | 2013 | Antimicrob. Agents Chemother. | pmid:23208707 |
Li X et al. | Synthesis and antibacterial evaluation of novel 11,4″-disubstituted azithromycin analogs with greatly improved activity against erythromycin-resistant bacteria. | 2013 | Eur J Med Chem | pmid:23229056 |
Nunez-Samudio V and Chesneau O | Functional interplay between the ATP binding cassette Msr(D) protein and the membrane facilitator superfamily Mef(E) transporter for macrolide resistance in Escherichia coli. | 2013 | Res. Microbiol. | pmid:23261969 |
Hisatsune J et al. | Emergence of Staphylococcus aureus carrying multiple drug resistance genes on a plasmid encoding exfoliative toxin B. | 2013 | Antimicrob. Agents Chemother. | pmid:24080652 |