erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Wang P et al. | Serotype distribution, antimicrobial resistance, and molecular characterization of invasive group B Streptococcus isolates recovered from Chinese neonates. | 2015 | Int. J. Infect. Dis. | pmid:26141418 |
Høye S | An extraordinary tale of an ordinary case. | 2015 | Tidsskr. Nor. Laegeforen. | pmid:26130550 |
Loose LM et al. | Adolescent with respiratory impairments and short-lived fever. | 2015 | Tidsskr. Nor. Laegeforen. | pmid:26130549 |
Liu J et al. | Preparation and characterization of erythromycin molecularly imprinted polymers based on distillation-precipitation polymerization. | 2015 | J Sep Sci | pmid:26118901 |
Fathollahipour S et al. | Electrospinning of PVA/chitosan nanocomposite nanofibers containing gelatin nanoparticles as a dual drug delivery system. | 2015 | J Biomed Mater Res A | pmid:26112829 |
Xing L et al. | ErmF and ereD are responsible for erythromycin resistance in Riemerella anatipestifer. | 2015 | PLoS ONE | pmid:26107936 |
Dridi B et al. | Differences in antibiotic-induced oxidative stress responses between laboratory and clinical isolates of Streptococcus pneumoniae. | 2015 | Antimicrob. Agents Chemother. | pmid:26100702 |
Czarnetzki C et al. | Erythromycin for Gastric Emptying in Patients Undergoing General Anesthesia for Emergency Surgery: A Randomized Clinical Trial. | 2015 | JAMA Surg | pmid:26083537 |
Patti MG | Erythromycin Use Before Induction of General Endotracheal Anesthesia. | 2015 | JAMA Surg | pmid:26083012 |
Haenen CC et al. | [Rosacea fulminans in pregnancy]. | 2015 | Ned Tijdschr Geneeskd | pmid:26058762 |
Gagliotti C et al. | A regionwide intervention to promote appropriate antibiotic use in children reversed trends in erythromycin resistance to Streptococcus pyogenes. | 2015 | Acta Paediatr. | pmid:26058421 |
Dermota U et al. | Survey of community-associated-methicillin-Resistant Staphylococcus aureus in Slovenia: identification of community-associated and livestock-associated clones. | 2015 | Int. J. Med. Microbiol. | pmid:26055648 |
Drouet M et al. | Endothelial Cell Toxicity of Vancomycin Infusion Combined with Other Antibiotics. | 2015 | Antimicrob. Agents Chemother. | pmid:26055373 |
Reeves M et al. | Acute colonic pseudo-obstruction in pregnancy. | 2015 | ANZ J Surg | pmid:26044983 |
Koutsogiannidis CP et al. | Decreased DNA Disruption in the Porcine Neocortex with Erythromycin Preconditioning during Prolonged Hypothermic Circulatory Arrest: Evidence for Neuroprotection. | 2015 | J Card Surg | pmid:25858150 |
KovaÄ J et al. | Antibiotic resistance modulation and modes of action of (-)-α-pinene in Campylobacter jejuni. | 2015 | PLoS ONE | pmid:25830640 |
Abukar AA et al. | Unusual cause of infective endocarditis in an elderly patient with a rare condition. | 2015 | BMJ Case Rep | pmid:25820110 |
Aydin S et al. | Combined effect of erythromycin, tetracycline and sulfamethoxazole on performance of anaerobic sequencing batch reactors. | 2015 | Bioresour. Technol. | pmid:25817031 |
Cui B et al. | Effects of erythromycin on the phenotypic and genotypic biofilm expression in two clinical Staphylococcus capitis subspecies and a functional analysis of Ica proteins in S. capitis. | 2015 | J. Med. Microbiol. | pmid:25813821 |
Chew ML et al. | Effect of the gastrointestinal prokinetic agent erythromycin on the pharmacokinetics of pregabalin controlled-release in healthy individuals: a phase I, randomized crossover trial. | 2015 | Clin Drug Investig | pmid:25808394 |
Ericson JE et al. | Use and Safety of Erythromycin and Metoclopramide in Hospitalized Infants. | 2015 | J. Pediatr. Gastroenterol. Nutr. | pmid:25806675 |
Aydin S et al. | Application of real-time PCR to determination of combined effect of antibiotics on Bacteria, Methanogenic Archaea, Archaea in anaerobic sequencing batch reactors. | 2015 | Water Res. | pmid:25792437 |
Zhu Y et al. | Biochemical and pharmacological characterizations of ESI-09 based EPAC inhibitors: defining the ESI-09 "therapeutic window". | 2015 | Sci Rep | pmid:25791905 |
Wang P et al. | Serotypes, antibiotic susceptibilities, and multi-locus sequence type profiles of Streptococcus agalactiae isolates circulating in Beijing, China. | 2015 | PLoS ONE | pmid:25781346 |
Zhou Y et al. | Rapid and selective extraction of multiple macrolide antibiotics in foodstuff samples based on magnetic molecularly imprinted polymers. | 2015 | Talanta | pmid:25770599 |
Tojima I et al. | Anti-inflammatory effects of a novel non-antibiotic macrolide, EM900, on mucus secretion of airway epithelium. | 2015 | Auris Nasus Larynx | pmid:25769240 |
Hao H et al. | Identification of Campylobacter jejuni and determination of point mutations associated with macrolide resistance using a multiplex TaqMan MGB real-time PCR. | 2015 | J. Appl. Microbiol. | pmid:25766481 |
Nonaka L et al. | Novel macrolide-resistance genes, mef(C) and mph(G), carried by plasmids from Vibrio and Photobacterium isolated from sediment and seawater of a coastal aquaculture site. | 2015 | Lett. Appl. Microbiol. | pmid:25765542 |
Mills RO et al. | Epidemiology of pneumococcal carriage in children under five years of age in Accra, Ghana. | 2015 | Infect Dis (Lond) | pmid:25761718 |
GarcÃa-Mayor MA et al. | Occurrence of erythromycin residues in sheep milk. Validation of an analytical method. | 2015 | Food Chem. Toxicol. | pmid:25637760 |
van Eijk E et al. | Complete genome sequence of the Clostridium difficile laboratory strain 630Δerm reveals differences from strain 630, including translocation of the mobile element CTn5. | 2015 | BMC Genomics | pmid:25636331 |
Gao P et al. | Impacts of coexisting antibiotics, antibacterial residues, and heavy metals on the occurrence of erythromycin resistance genes in urban wastewater. | 2015 | Appl. Microbiol. Biotechnol. | pmid:25631280 |
Lin X et al. | Macrolides for diffuse panbronchiolitis. | 2015 | Cochrane Database Syst Rev | pmid:25618845 |
Sakata H | The change of macrolide resistance rates in group A Streptococcus isolates from children between 2002 and 2013 in Asahikawa city. | 2015 | J. Infect. Chemother. | pmid:25618777 |
Johnson AC et al. | Assessing the concentrations and risks of toxicity from the antibiotics ciprofloxacin, sulfamethoxazole, trimethoprim and erythromycin in European rivers. | 2015 | Sci. Total Environ. | pmid:25617699 |
Wang P et al. | Development of an efficient conjugation-based genetic manipulation system for Pseudoalteromonas. | 2015 | Microb. Cell Fact. | pmid:25612661 |
Chiaverini C et al. | Oral erythromycin therapy in epidermolysis bullosa simplex generalized severe. | 2015 | Br. J. Dermatol. | pmid:25601422 |
Li Z et al. | New erythromycin derivatives enhance β-lactam antibiotics against methicillin-resistant Staphylococcus aureus. | 2015 | Lett. Appl. Microbiol. | pmid:25588530 |
Gardiner SJ et al. | Antibiotics for community-acquired lower respiratory tract infections secondary to Mycoplasma pneumoniae in children. | 2015 | Cochrane Database Syst Rev | pmid:25566754 |
Azadegan A et al. | Detection of the efflux-mediated erythromycin resistance transposon in Streptococcus pneumoniae. | 2015 | Ann Lab Med | pmid:25553281 |
Wu H et al. | Capturing the target genes of BldD in Saccharopolyspora erythraea using improved genomic SELEX method. | 2015 | Appl. Microbiol. Biotechnol. | pmid:25549616 |
Cetecioglu Z et al. | Acute effect of erythromycin on metabolic transformations of volatile fatty acid mixture under anaerobic conditions. | 2015 | Chemosphere | pmid:25542637 |
Novak I and KovaÄ B | Electronic structure of antibiotic erythromycin. | 2015 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:25528514 |
Blix HS et al. | Antibiotic prescriptions and cycles of Mycoplasma pneumoniae infections in Norway: can a nationwide prescription register be used for surveillance? | 2015 | Epidemiol. Infect. | pmid:25388750 |
MarÃn M et al. | Clostridium difficile isolates with high linezolid MICs harbor the multiresistance gene cfr. | 2015 | Antimicrob. Agents Chemother. | pmid:25385106 |
Igbinosa IH | Prevalence and detection of antibiotic-resistant determinant in Salmonella isolated from food-producing animals. | 2015 | Trop Anim Health Prod | pmid:25348646 |
Wang Z et al. | Hapten synthesis, monoclonal antibody production and development of a competitive indirect enzyme-linked immunosorbent assay for erythromycin in milk. | 2015 | Food Chem | pmid:25308648 |
Galvidis I et al. | Group determination of 14-membered macrolide antibiotics and azithromycin using antibodies against common epitopes. | 2015 | Anal. Biochem. | pmid:25256165 |
Kam Y et al. | Sweat but no gain: inhibiting proliferation of multidrug resistant cancer cells with "ersatzdroges". | 2015 | Int. J. Cancer | pmid:25156304 |
Hawkins PA et al. | Mobile elements and chromosomal changes associated with MLS resistance phenotypes of invasive pneumococci recovered in the United States. | 2015 | Microb. Drug Resist. | pmid:25115711 |
Vallianou N et al. | Prevalence of macrolide, lincosamide, and streptogramin resistance among staphylococci in a tertiary care hospital in Athens, Greece. | 2015 | J Chemother | pmid:25112954 |
Kempe H et al. | Molecularly imprinted polymer nanocarriers for sustained release of erythromycin. | 2015 | Pharm. Res. | pmid:25103333 |
Lo HH et al. | Antibiotic susceptibility pattern and erythromycin resistance mechanisms in beta-hemolytic group G Streptococcus dysgalactiae subspecies equisimilis isolates from central Taiwan. | 2015 | J Microbiol Immunol Infect | pmid:24856419 |
Yang J et al. | Improving heterologous polyketide production in Escherichia coli by transporter engineering. | 2015 | Appl. Microbiol. Biotechnol. | pmid:26062534 |
Muralidharan V and Striepen B | Teaching old drugs new tricks to stop malaria invasion in its tracks. | 2015 | BMC Biol. | pmid:26349580 |
Pavlova A and Gumbart JC | Parametrization of macrolide antibiotics using the force field toolkit. | 2015 | J Comput Chem | pmid:26280362 |
Cheng C et al. | Ciprofloxacin plus erythromycin or ambroxol ameliorates endotracheal tube-associated Pseudomonas aeruginosa biofilms in a rat model. | 2015 | Pathol. Res. Pract. | pmid:26601615 |
Feng T et al. | Insights into resistance mechanism of the macrolide biosensor protein MphR(A) binding to macrolide antibiotic erythromycin by molecular dynamics simulation. | 2015 | J. Comput. Aided Mol. Des. | pmid:26564143 |
Aydın S et al. | Inhibitory effect of erythromycin, tetracycline and sulfamethoxazole antibiotics on anaerobic treatment of a pharmaceutical wastewater. | 2015 | Water Sci. Technol. | pmid:26038926 |
Daghighi S et al. | Influence of antibiotic pressure on bacterial bioluminescence, with emphasis on Staphylococcus aureus. | 2015 | Int. J. Antimicrob. Agents | pmid:26526893 |
Bravo-Rodriguez K et al. | Substrate Flexibility of a Mutated Acyltransferase Domain and Implications for Polyketide Biosynthesis. | 2015 | Chem. Biol. | pmid:26526102 |
Bérard A et al. | Use of macrolides during pregnancy and the risk of birth defects: a population-based study. | 2015 | Pharmacoepidemiol Drug Saf | pmid:26513406 |
Dixit S and Park JH | Enantioseparation of basic chiral drugs on a carbamoylated erythromycin-zirconia hybrid monolith using capillary electrochromatography. | 2015 | J Chromatogr A | pmid:26372443 |
Michael-Kordatou I et al. | Erythromycin oxidation and ERY-resistant Escherichia coli inactivation in urban wastewater by sulfate radical-based oxidation process under UV-C irradiation. | 2015 | Water Res. | pmid:26360228 |
Arinto-Garcia R et al. | Comparing Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry and Phenotypic and Molecular Methods for Identification of Species within the Streptococcus anginosus Group. | 2015 | J. Clin. Microbiol. | pmid:26354817 |
Han X et al. | Synthesis and structure-activity relationships of novel 9-oxime acylides with improved bactericidal activity. | 2015 | Bioorg. Med. Chem. | pmid:26349628 |
Wróblewska M and Winnicka K | The Effect of Cationic Polyamidoamine Dendrimers on Physicochemical Characteristics of Hydrogels with Erythromycin. | 2015 | Int J Mol Sci | pmid:26343637 |
Bolukaoto JY et al. | Antibiotic resistance of Streptococcus agalactiae isolated from pregnant women in Garankuwa, South Africa. | 2015 | BMC Res Notes | pmid:26289147 |
Liao CH et al. | DasR is a pleiotropic regulator required for antibiotic production, pigment biosynthesis, and morphological development in Saccharopolyspora erythraea. | 2015 | Appl. Microbiol. Biotechnol. | pmid:26272095 |
Å mitran A et al. | Effects of penicillin and erythromycin on adherence of invasive and noninvasive isolates of Streptococcus pyogenes to laminin. | 2015 | Mem. Inst. Oswaldo Cruz | pmid:26270594 |
Wang YL et al. | Development of a Method for the Analysis of Multiclass Antibiotic Residues in Milk Using QuEChERS and Liquid Chromatography-Tandem Mass Spectrometry. | 2015 | Foodborne Pathog. Dis. | pmid:26258263 |
Prohl A et al. | Enrofloxacin and macrolides alone or in combination with rifampicin as antimicrobial treatment in a bovine model of acute Chlamydia psittaci infection. | 2015 | PLoS ONE | pmid:25768665 |
Enayati M et al. | Virulence and antimicrobial resistance of Enterococcus faecium isolated from water samples. | 2015 | Lett. Appl. Microbiol. | pmid:26249819 |
Mazumdar G and Shome K | Stevens-Johnson syndrome following use of metronidazole in a dental patient. | 2014 Jan-Feb | Indian J Pharmacol | pmid:24550598 |
Chen D et al. | Identification and characterization of a new erythromycin biosynthetic gene cluster in Actinopolyspora erythraea YIM90600, a novel erythronolide-producing halophilic actinomycete isolated from salt field. | 2014 | PLoS ONE | pmid:25250723 |
Brenciani A et al. | ICESp1116, the genetic element responsible for erm(B)-mediated, inducible erythromycin resistance in Streptococcus pyogenes, belongs to the TnGBS family of integrative and conjugative elements. | 2014 | Antimicrob. Agents Chemother. | pmid:24449773 |
Yu ZC et al. | Development of a genetic system for the deep-sea psychrophilic bacterium Pseudoalteromonas sp. SM9913. | 2014 | Microb. Cell Fact. | pmid:24450434 |
Barnes P and Chauhan M | Chancroid - desperate patient makes own diagnosis. | 2014 | Int J STD AIDS | pmid:24535694 |
Wang S et al. | Comparison of microbial communities in sequencing batch reactors (SBRs) exposed to trace erythromycin and erythromycin-Hâ‚‚O. | 2014 | Appl. Microbiol. Biotechnol. | pmid:24072160 |
Pinto TC et al. | Conjugative transfer of resistance determinants among human and bovine Streptococcus agalactiae. | 2014 | Braz. J. Microbiol. | pmid:25477908 |
He S et al. | [Clinical analysis of scrub typhus-associated hemophagocytic syndrome]. | 2014 | Zhonghua Er Ke Za Zhi | pmid:25476431 |
Luminos M et al. | Nasopharyngeal carriage of Streptococcus pneumoniae in Romanian children before the introduction of the pneumococcal conjugated vaccination into the national immunization programme: a national, multi-centre, cross-sectional observational study. | 2014 | Int. J. Infect. Dis. | pmid:25461243 |
Sugawara E and Nikaido H | Properties of AdeABC and AdeIJK efflux systems of Acinetobacter baumannii compared with those of the AcrAB-TolC system of Escherichia coli. | 2014 | Antimicrob. Agents Chemother. | pmid:25246403 |
Corona PS et al. | Case report: first report of a prosthetic joint infection caused by Facklamia hominis. | 2014 | Diagn. Microbiol. Infect. Dis. | pmid:25245196 |
Ziupa D et al. | Pronounced effects of HERG-blockers E-4031 and erythromycin on APD, spatial APD dispersion and triangulation in transgenic long-QT type 1 rabbits. | 2014 | PLoS ONE | pmid:25244401 |
Bos JC et al. | Antimicrobial susceptibility of Streptococcus pneumoniae in adult patients with pneumococcal pneumonia in an urban hospital in Mozambique. | 2014 | BMC Res Notes | pmid:24568650 |
Flamm RK et al. | Antimicrobial activity of ceftaroline tested against drug-resistant subsets of Streptococcus pneumoniae from U.S. medical centers. | 2014 | Antimicrob. Agents Chemother. | pmid:24514082 |
Sahu AK et al. | Formulation optimization of erythromycin solid lipid nanocarrier using response surface methodology. | 2014 | Biomed Res Int | pmid:25045692 |
Arakawa K | Genetic and biochemical analysis of the antibiotic biosynthetic gene clusters on the Streptomyces linear plasmid. | 2014 | Biosci. Biotechnol. Biochem. | pmid:25036669 |
Pasquaroli S et al. | Erythromycin- and copper-resistant Enterococcus hirae from marine sediment and co-transfer of erm(B) and tcrB to human Enterococcus faecalis. | 2014 | Diagn. Microbiol. Infect. Dis. | pmid:25017384 |
Yeung SW et al. | Comparison of the effect of penicillins versus erythromycin in preventing neonatal group B streptococcus infection in active carriers following preterm prelabor rupture of membranes. | 2014 | Taiwan J Obstet Gynecol | pmid:25017269 |
Nuyujukian DS et al. | Medication use and multiple myeloma risk in Los Angeles County. | 2014 | Cancer Causes Control | pmid:24981100 |
Sakamoto N et al. | Bronchiolitis in a patient with ulcerative colitis treated with erythromycin. | 2014 | Intern. Med. | pmid:24739609 |
Szemraj M et al. | Macrolide, lincosamide, and streptogramin B resistance in lipophilic Corynebacteria inhabiting healthy human skin. | 2014 | Microb. Drug Resist. | pmid:24735183 |
Moreno LZ et al. | Characterization of antibiotic resistance in Listeria spp. isolated from slaughterhouse environments, pork and human infections. | 2014 | J Infect Dev Ctries | pmid:24727506 |
Geng Q et al. | Molecular characterization and antimicrobial susceptibility of Streptococcus pneumoniae isolated from children hospitalized with respiratory infections in Suzhou, China. | 2014 | PLoS ONE | pmid:24710108 |
Yosida M et al. | Involvement of cAMP/EPAC/TRPM2 activation in glucose- and incretin-induced insulin secretion. | 2014 | Diabetes | pmid:24824430 |
Hellmann-Regen J et al. | Do tetracyclines and erythromycin exert anti-acne effects by inhibition of P450-mediated degradation of retinoic acid? | 2014 | Exp. Dermatol. | pmid:24690039 |
Siira L et al. | Antimicrobial resistance in relation to sero- and genotypes among invasive Streptococcus pneumoniae in Finland, 2007-2011. | 2014 | Microb. Drug Resist. | pmid:24266666 |
Xu J et al. | Phenotypic and genotypic antimicrobial resistance traits of foodborne Staphylococcus aureus isolates from Shanghai. | 2014 | J. Food Sci. | pmid:24689704 |