erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Diarrhea D003967 32 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Uremia D014511 33 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Acute Lung Injury D055371 33 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Epilepsy D004827 35 associated lipids
Fever D005334 35 associated lipids
Acne Vulgaris D000152 35 associated lipids
Glomerulonephritis D005921 35 associated lipids
Heart Failure D006333 36 associated lipids
Nervous System Diseases D009422 37 associated lipids
Lung Diseases D008171 37 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Arthritis D001168 41 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Hypotension D007022 41 associated lipids
Leukemia P388 D007941 43 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Psoriasis D011565 47 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Pain D010146 64 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Leukemia D007938 74 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Seizures D012640 87 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Weight Gain D015430 101 associated lipids
Hypertension D006973 115 associated lipids
Inflammation D007249 119 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Hemolysis D006461 131 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Edema D004487 152 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Body Weight D001835 333 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Sun XR et al. [Effect of motilin receptor agonist-erythromycin on the glucose responsive neurons in hypothalamus of rats]. 2005 Zhongguo Ying Yong Sheng Li Xue Za Zhi pmid:21162186
Lei PS et al. [Advance in synthesis of ketolides, a new class of erythromycin derivatives]. 2004 Zhongguo Yi Xue Ke Xue Yuan Xue Bao pmid:15379279
Wang H et al. Demethylation capacity of human fetal adrenal mitochondrial cytochrome P-450 in vitro. 1999 Zhongguo Yao Li Xue Bao pmid:10452125
Huang SK et al. [A combined perfusion-compartmental pharmacokinetic model used to estimate presystemic metabolism of erythromycin in dogs]. 1986 Zhongguo Yao Li Xue Bao pmid:2954396
Ye H et al. Antimycoplasmal activities of (S)-(-)-9-fluoro-2,3-dihydro-3-methyl-10 -[4-(2-pyridyl)-1-piperazinyl]-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine -6-carboxylic acid (YH-6) in comparison with other antibiotics in vitro. 1999 Zhongguo Yao Li Xue Bao pmid:11270970
Du Y and He Q [The mechanism of alleviation of paraquat induced vascular endothelial permeability by erythromycin through adenosine 3'5'-cyclic monophosphate pathway]. 2009 Zhongguo Wei Zhong Bing Ji Jiu Yi Xue pmid:19930884
Lu NF et al. [Study of erythromycin and metoclopramide in treatment of feeding intolerance of critically ill patients in intensive care unit]. 2010 Zhongguo Wei Zhong Bing Ji Jiu Yi Xue pmid:20092709
Yu M et al. [Mechanism reversing MDR of K562/A02 by garlicin combined with erythromycin]. 2008 Zhongguo Shi Yan Xue Ye Xue Za Zhi pmid:18928592
Xie L et al. [Efficacy of low-dose oral erythromycin as an adjuvant therapy for cytomegalovirus infection]. 2010 Zhongguo Dang Dai Er Ke Za Zhi pmid:20199738
Yang Y [Mechanism and clinical application of erythromycin as a gastrointestinal prokinetic agent in children]. 2008 Zhongguo Dang Dai Er Ke Za Zhi pmid:18289489
Thomas W and Speer CP Prevention and therapy of bronchopulmonary dysplasia - evidence and clinical practice. 2007 Zhongguo Dang Dai Er Ke Za Zhi pmid:17582275
Wang LQ et al. [Pharmacokinetics of erythromycin stinoprate capsule]. 2005 Zhong Nan Da Xue Xue Bao Yi Xue Ban pmid:15898434
Lin XM et al. [Influence of neferine and erythromycin on cellular GSH concentration in K562/A02 cell line]. 2004 Zhong Nan Da Xue Xue Bao Yi Xue Ban pmid:16136961
Xu G [Regulating effect of electro-acupuncture on dysrythmia of gastro-colonic electric activity induced by erythromycine in rabbits]. 1994 Zhen Ci Yan Jiu pmid:7834859
Wu DQ et al. [The expression of transforming growth factor beta-1 in rat model of chronic obstructive pulmonary disease and the effects of early drugs intervention]. 2004 Zhejiang Da Xue Xue Bao Yi Xue Ban pmid:15476327
Liashenko IuI [Humoral immunity indices in angina and chronic tonsillitis and the effect on it of antibiotics]. 1978 Zh. Mikrobiol. Epidemiol. Immunobiol. pmid:665045
Klimchuk ND [Preventive effect of several antibiotics in experimental rickettsial infections]. 1978 Zh. Mikrobiol. Epidemiol. Immunobiol. pmid:742277
Gamaleia NB and Levashev VS [Biological properties and mechanisms of development of bacteria resistant to fusidin, erythromycin and chloramphenicol]. 1978 Zh. Mikrobiol. Epidemiol. Immunobiol. pmid:96638
Zueva VS and Pavlov EP [The prevalence of staphylococci with extrachromosomal drug resistance factors in different collectives]. 1972 Zh. Mikrobiol. Epidemiol. Immunobiol. pmid:4563840
Balaeva NM and Frolova OM [Production of the mutant E strain of Rickettsia prowazekii by mutagen exposure]. 1982 Zh. Mikrobiol. Epidemiol. Immunobiol. pmid:6818794