erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Diarrhea D003967 32 associated lipids
Peripheral Nervous System Diseases D010523 33 associated lipids
Uremia D014511 33 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Acute Lung Injury D055371 33 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Glomerulonephritis D005921 35 associated lipids
Epilepsy D004827 35 associated lipids
Fever D005334 35 associated lipids
Acne Vulgaris D000152 35 associated lipids
Heart Failure D006333 36 associated lipids
Nervous System Diseases D009422 37 associated lipids
Lung Diseases D008171 37 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Arthritis D001168 41 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Hypotension D007022 41 associated lipids
Hypersensitivity, Delayed D006968 43 associated lipids
Leukemia P388 D007941 43 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Psoriasis D011565 47 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Pain D010146 64 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Leukemia D007938 74 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Seizures D012640 87 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Weight Gain D015430 101 associated lipids
Hypertension D006973 115 associated lipids
Inflammation D007249 119 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Hemolysis D006461 131 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Edema D004487 152 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Body Weight D001835 333 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Sadeghi J and Mansouri S Molecular characterization and antibiotic resistance of clinical isolates of methicillin-resistant Staphylococcus aureus obtained from Southeast of Iran (Kerman). 2014 APMIS pmid:24033803
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Silva CM et al. Population dynamics and antimicrobial susceptibility of Aeromonas spp. along a salinity gradient in an urban estuary in Northeastern Brazil. 2014 Mar. Pollut. Bull. pmid:25455376
Fan L and Xu J [Application progress of macrolide sustained therapy for bronchiectasis]. 2014 Zhonghua Jie He He Hu Xi Za Zhi pmid:24694975
Leirós M et al. Mitigation of ROS insults by Streptomyces secondary metabolites in primary cortical neurons. 2014 ACS Chem Neurosci pmid:24219236
Westerhof J et al. Completion rate of small bowel capsule endoscopy is higher after erythromycin compared to domperidone. 2014 BMC Gastroenterol pmid:25234278
Badri T et al. [Erythrasma: study of 16 cases]. 2014 Tunis Med pmid:25224418
Dörries K et al. Impact of antibiotics with various target sites on the metabolome of Staphylococcus aureus. 2014 Antimicrob. Agents Chemother. pmid:25224006
Zhang Y et al. [Erythromycin restores oxidative stress-induced corticosteroid responsiveness of human THP-1 cells by up-regulating the expression of histone deacetylase 2]. 2014 Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi pmid:24721407
Hoover WD et al. Topical antibiotic monotherapy prescribing practices in acne vulgaris. 2014 J Dermatolog Treat pmid:24171409
Iatrou EI et al. Consumption-based approach for predicting environmental risk in Greece due to the presence of antimicrobials in domestic wastewater. 2014 Environ Sci Pollut Res Int pmid:24981036
Ramos V et al. [Mobile genetic elements associated with erythromycin-resistant isolates of Streptococcus pneumoniae in Colombia]. 2014 Biomedica pmid:24968052
Xu J et al. Phenotypic and genotypic antimicrobial resistance traits of foodborne Staphylococcus aureus isolates from Shanghai. 2014 J. Food Sci. pmid:24689704
Wang D et al. Structural and environmental features of novel mdfA variant and mdfA genes in recombinant regions of Escherichia coli. 2014 Microb. Drug Resist. pmid:24684286
Arenz S et al. Molecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptide. 2014 Nat Commun pmid:24662426
Fernández Fuentes MA et al. Synergistic activity of biocides and antibiotics on resistant bacteria from organically produced foods. 2014 Microb. Drug Resist. pmid:24660956
Rodríguez-Gutiérrez R et al. Herpes zoster ophthalmicus masked by hymenoptera stings. 2014 Am. J. Med. Sci. pmid:23085675
Kim S and Muthusamy VR Prophylactic erythromycin in acute upper gastrointestinal bleeding: moving forward in improving endoscopic efficacy. 2013 Sep-Oct Saudi J Gastroenterol pmid:24045591
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Manchia M et al. Repeated erythromycin/codeine-induced psychotic mania. 2013 Sep-Oct Clin Neuropharmacol pmid:24045612
De Alwis HG et al. Determination of erythromycin in medicated salmonid fish feed by liquid chromatography and UV spectroscopy. 2013 Nov-Dec J AOAC Int pmid:24645499
Zou X et al. Biochemical parameters of Saccharopolyspora erythraea during feeding ammonium sulphate in erythromycin biosynthesis phase. 2013 Mar-Apr Prikl. Biokhim. Mikrobiol. pmid:23795479
Jiang M et al. Improved heterologous erythromycin A production through expression plasmid re-design. 2013 Jul-Aug Biotechnol. Prog. pmid:23804312
Lynch M et al. Bullae of the hands, feet, and perioral area in a 3-month-old infant. Bullous pemphigoid. 2013 Jan-Feb Pediatr Dermatol pmid:23316718
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Utsunomiya S et al. Critical residues in the transmembrane helical bundle domains of the human motilin receptor for erythromycin binding and activity. 2013 Regul. Pept. pmid:23142315
Li YJ et al. EM, EM703 inhibit NF-kB activation induced by oxidative stress from diesel exhaust particle in human bronchial epithelial cells: importance in IL-8 transcription. 2013 Pulm Pharmacol Ther pmid:23291319
Guo L et al. Refining the human iPSC-cardiomyocyte arrhythmic risk assessment model. 2013 Toxicol. Sci. pmid:24052561
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Jiang M et al. Deoxysugar pathway interchange for erythromycin analogues heterologously produced through Escherichia coli. 2013 Metab. Eng. pmid:24060454
Gold RM and Lawhon SD Incidence of inducible clindamycin resistance in Staphylococcus pseudintermedius from dogs. 2013 J. Clin. Microbiol. pmid:24025915
Henson AM et al. Detection of Streptococcus pyogenes by use of Illumigene group A Streptococcus assay. 2013 J. Clin. Microbiol. pmid:24048538
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Di Salvo A et al. Pharmacokinetics and residue depletion of erythromycin in rainbow trout Oncorhynchus mykiss (Walbaum). 2013 J. Fish Dis. pmid:24118016
Avci O et al. A comparison between the effectiveness of erythromycin, single-dose clarithromycin and topical fusidic acid in the treatment of erythrasma. 2013 J Dermatolog Treat pmid:21923567
Link-Gelles R et al. Geographic and temporal trends in antimicrobial nonsusceptibility in Streptococcus pneumoniae in the post-vaccine era in the United States. 2013 J. Infect. Dis. pmid:23852588
Pohl O et al. Effects of erythromycin at steady-state concentrations on the pharmacokinetics of ulipristal acetate. 2013 J Clin Pharm Ther pmid:24102384
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Gomes DL et al. SubMICs of penicillin and erythromycin enhance biofilm formation and hydrophobicity of Corynebacterium diphtheriae strains. 2013 J. Med. Microbiol. pmid:23449875
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Jiang M et al. The logic, experimental steps, and potential of heterologous natural product biosynthesis featuring the complex antibiotic erythromycin A produced through E. coli. 2013 J Vis Exp pmid:23354010
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