erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Jiang M and Pfeifer BA | Metabolic and pathway engineering to influence native and altered erythromycin production through E. coli. | 2013 | Metab. Eng. | pmid:23747605 |
Xia Q et al. | Adaptive mechanisms of Campylobacter jejuni to erythromycin treatment. | 2013 | BMC Microbiol. | pmid:23767761 |
Guo MT et al. | Ultraviolet reduction of erythromycin and tetracycline resistant heterotrophic bacteria and their resistance genes in municipal wastewater. | 2013 | Chemosphere | pmid:24055024 |
Ong SJ et al. | Staphylococcus aureus keratitis: a review of hospital cases. | 2013 | PLoS ONE | pmid:24244625 |
Chroboczek T et al. | Clonal complex 398 methicillin susceptible Staphylococcus aureus: a frequent unspecialized human pathogen with specific phenotypic and genotypic characteristics. | 2013 | PLoS ONE | pmid:24260092 |
PetráÄková D et al. | Fitness and proteome changes accompanying the development of erythromycin resistance in a population of Escherichia coli grown in continuous culture. | 2013 | Microbiologyopen | pmid:23996919 |
Weber JM et al. | Biotransformation and recovery of the isoflavones genistein and daidzein from industrial antibiotic fermentations. | 2013 | Appl. Microbiol. Biotechnol. | pmid:23604533 |
Li X et al. | Synthesis and antibacterial evaluation of novel 11,4″-disubstituted azithromycin analogs with greatly improved activity against erythromycin-resistant bacteria. | 2013 | Eur J Med Chem | pmid:23229056 |
Nunez-Samudio V and Chesneau O | Functional interplay between the ATP binding cassette Msr(D) protein and the membrane facilitator superfamily Mef(E) transporter for macrolide resistance in Escherichia coli. | 2013 | Res. Microbiol. | pmid:23261969 |
Heelan K et al. | Panton-Valentine leukocidin-producing Staphylococcal aureus: report of four siblings. | 2012 Sep-Oct | Pediatr Dermatol | pmid:21906149 |
Lian W et al. | Electrochemical sensor based on gold nanoparticles fabricated molecularly imprinted polymer film at chitosan-platinum nanoparticles/graphene-gold nanoparticles double nanocomposites modified electrode for detection of erythromycin. | 2012 Oct-Dec | Biosens Bioelectron | pmid:22683249 |
Hapa A et al. | Childhood pityriasis lichenoides and oral erythromycin. | 2012 Nov-Dec | Pediatr Dermatol | pmid:22639857 |
Asai N et al. | A successfully treated case of parainfluenza virus 3 pneumonia mimicking influenza pneumonia. | 2012 Nov-Dec | J Bras Pneumol | pmid:23288130 |
Clementson B and Smidt AC | Periorificial dermatitis due to systemic corticosteroids in children: report of two cases. | 2012 May-Jun | Pediatr Dermatol | pmid:22122785 |
Kuhn M et al. | Feed restriction enhances the depressive effects of erythromycin on equine hindgut microbial metabolism in vitro. | 2012 Jul-Aug | Berl. Munch. Tierarztl. Wochenschr. | pmid:22919930 |
Jiang RS et al. | Efficacy of Chinese herbal medicine compared with a macrolide in the treatment of chronic rhinosinusitis without nasal polyps. | 2012 Jul-Aug | Am J Rhinol Allergy | pmid:22801017 |
Kuehne SA and Minton NP | ClosTron-mediated engineering of Clostridium. | 2012 Jul-Aug | Bioengineered | pmid:22750794 |
Miguel AI et al. | Pediatric ocular rosacea: 2 cases. | 2012 Jul-Aug | Eur J Ophthalmol | pmid:22267454 |
Amatya A et al. | Comparative study of effectiveness of oral acyclovir with oral erythromycin in the treatment of Pityriasis rosea. | 2012 Jan-Mar | Kathmandu Univ Med J (KUMJ) | pmid:22971864 |
Zhang H et al. | Improved E. coli erythromycin A production through the application of metabolic and bioprocess engineering. | 2012 Jan-Feb | Biotechnol. Prog. | pmid:21905273 |
Pehr K | Mycophenolate mofetil and erythromycin for bullous lupus erythematosus of childhood. | 2012 Jan-Feb | J Cutan Med Surg | pmid:22417996 |
Abdel Fattah NS and Darwish YW | Antibiogram testing of pediatric skin infections in the era of methicillin-resistant Staphylococci aureus: an Egyptian University Hospital-based study. | 2012 | Int. J. Dermatol. | pmid:22928620 |
Kjeldgaard J et al. | Residual antibiotics disrupt meat fermentation and increase risk of infection. | 2012 | MBio | pmid:22930338 |
Sakatis MZ et al. | Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. | 2012 | Chem. Res. Toxicol. | pmid:22931300 |
Krasniqi S et al. | Blood, tissue, and intracellular concentrations of erythromycin and its metabolite anhydroerythromycin during and after therapy. | 2012 | Antimicrob. Agents Chemother. | pmid:22083477 |
Nimgaonkar A et al. | Gastrointestinal dysmotility. | 2012 | Dig. Dis. Sci. | pmid:22038542 |
Fazeli M et al. | Erythromycin enhances abomasal emptying in healthy unweaned lambs as shown by acetaminophen absorption test. | 2012 | J. Vet. Pharmacol. Ther. | pmid:22066489 |
Kumar R et al. | Synthesis and antibacterial activity of a novel series of acylides active against community acquired respiratory pathogens. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22153939 |
Reutenauer-Patte J et al. | Urocortins improve dystrophic skeletal muscle structure and function through both PKA- and Epac-dependent pathways. | 2012 | Am. J. Pathol. | pmid:22192627 |
Villaseñor-Sierra A et al. | Phenotypes and genotypes of erythromycin-resistant Streptococcus pyogenes strains isolated from invasive and non-invasive infections from Mexico and the USA during 1999-2010. | 2012 | Int. J. Infect. Dis. | pmid:22217469 |
Luangtongkum T et al. | Impaired fitness and transmission of macrolide-resistant Campylobacter jejuni in its natural host. | 2012 | Antimicrob. Agents Chemother. | pmid:22183170 |
Romøren M et al. | Pregnancy outcome after gestational exposure to erythromycin - a population-based register study from Norway. | 2012 | Br J Clin Pharmacol | pmid:22463376 |
Lee CH et al. | Case-crossover design: an alternative strategy for detecting drug-induced liver injury. | 2012 | J Clin Epidemiol | pmid:22445086 |
Blode H et al. | Evaluation of the effects of rifampicin, ketoconazole and erythromycin on the steady-state pharmacokinetics of the components of a novel oral contraceptive containing estradiol valerate and dienogest in healthy postmenopausal women. | 2012 | Contraception | pmid:22445438 |
Kanazu T et al. | Investigation of drug-drug interaction via mechanism-based inhibition of cytochrome P450 3A by macrolides in dexamethasone-treated female rats. | 2012 | Biopharm Drug Dispos | pmid:22447511 |
Sui Q et al. | Identification of priority pharmaceuticals in the water environment of China. | 2012 | Chemosphere | pmid:22591850 |
Constable PD et al. | Evidence-based use of prokinetic drugs for abomasal disorders in cattle. | 2012 | Vet. Clin. North Am. Food Anim. Pract. | pmid:22374117 |
Mehra T et al. | Treatment of severe acne with low-dose isotretinoin. | 2012 | Acta Derm. Venereol. | pmid:22377969 |
Ogawa W et al. | Functional study of the novel multidrug efflux pump KexD from Klebsiella pneumoniae. | 2012 | Gene | pmid:22391093 |
Diacon AH et al. | Randomized pilot trial of eight weeks of bedaquiline (TMC207) treatment for multidrug-resistant tuberculosis: long-term outcome, tolerability, and effect on emergence of drug resistance. | 2012 | Antimicrob. Agents Chemother. | pmid:22391540 |
El-Adawy H et al. | Determination of antimicrobial sensitivities of Campylobacter jejuni isolated from commercial turkey farms in Germany. | 2012 | Avian Dis. | pmid:23397839 |
Mercer BM et al. | The antibiotic treatment of PPROM study: systemic maternal and fetal markers and perinatal outcomes. | 2012 | Am. J. Obstet. Gynecol. | pmid:22000668 |
Pendela M et al. | Combined use of liquid chromatography with mass spectrometry and nuclear magnetic resonance for the identification of degradation compounds in an erythromycin formulation. | 2012 | Anal Bioanal Chem | pmid:22002558 |
Wilson BB et al. | An atypical presentation of erythrasma. | 2012 | J. Am. Acad. Dermatol. | pmid:23062922 |
Zhou L et al. | Molecular characteristics of erythromycin-resistant Streptococcus pneumoniae from pediatric patients younger than five years in Beijing, 2010. | 2012 | BMC Microbiol. | pmid:23043378 |
Cannon JA et al. | Preoperative oral antibiotics reduce surgical site infection following elective colorectal resections. | 2012 | Dis. Colon Rectum | pmid:23044677 |
Kaul M et al. | A bactericidal guanidinomethyl biaryl that alters the dynamics of bacterial FtsZ polymerization. | 2012 | J. Med. Chem. | pmid:23050700 |
Du Plessis LH et al. | In vitro activity of Pheroid vesicles containing antibiotics against Plasmodium falciparum. | 2012 | J. Antibiot. | pmid:23093037 |
Marks LR et al. | The human milk protein-lipid complex HAMLET sensitizes bacterial pathogens to traditional antimicrobial agents. | 2012 | PLoS ONE | pmid:22905269 |
Weisman LE et al. | Appropriate antibiotic therapy improves Ureaplasma sepsis outcome in the neonatal mouse. | 2012 | Pediatr. Res. | pmid:22907617 |