erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Acneiform Eruptions D017486 3 associated lipids
Pityriasis Lichenoides D017514 2 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Lung Diseases, Interstitial D017563 5 associated lipids
Retropharyngeal Abscess D017703 2 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Limb Deformities, Congenital D017880 4 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Adrenocortical Carcinoma D018268 4 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Lymphoma, B-Cell, Marginal Zone D018442 1 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Gastroparesis D018589 2 associated lipids
Arthralgia D018771 8 associated lipids
Abdominal Abscess D018784 2 associated lipids
Sepsis D018805 11 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Postoperative Nausea and Vomiting D020250 1 associated lipids
Enterocolitis, Necrotizing D020345 3 associated lipids
Epidural Abscess D020802 1 associated lipids
Neuroaspergillosis D020953 2 associated lipids
Communicable Diseases, Emerging D021821 3 associated lipids
Pelvic Infection D034161 1 associated lipids
Acalculous Cholecystitis D042101 3 associated lipids
Ileus D045823 3 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Moraxellaceae Infections D045828 3 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Seroma D049291 2 associated lipids
Granulomatosis, Orofacial D051261 2 associated lipids
Kidney Diseases, Cystic D052177 3 associated lipids
Pneumonia, Ventilator-Associated D053717 1 associated lipids
Atrioventricular Block D054537 1 associated lipids
Acute Lung Injury D055371 33 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Occupational Injuries D060051 1 associated lipids
Vagus Nerve Injuries D061223 1 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Abdel Fattah NS and Darwish YW Antibiogram testing of pediatric skin infections in the era of methicillin-resistant Staphylococci aureus: an Egyptian University Hospital-based study. 2012 Int. J. Dermatol. pmid:22928620
Kjeldgaard J et al. Residual antibiotics disrupt meat fermentation and increase risk of infection. 2012 MBio pmid:22930338
Krasniqi S et al. Blood, tissue, and intracellular concentrations of erythromycin and its metabolite anhydroerythromycin during and after therapy. 2012 Antimicrob. Agents Chemother. pmid:22083477
Nimgaonkar A et al. Gastrointestinal dysmotility. 2012 Dig. Dis. Sci. pmid:22038542
Kumar R et al. Synthesis and antibacterial activity of a novel series of acylides active against community acquired respiratory pathogens. 2012 Bioorg. Med. Chem. Lett. pmid:22153939
Reutenauer-Patte J et al. Urocortins improve dystrophic skeletal muscle structure and function through both PKA- and Epac-dependent pathways. 2012 Am. J. Pathol. pmid:22192627
Romøren M et al. Pregnancy outcome after gestational exposure to erythromycin - a population-based register study from Norway. 2012 Br J Clin Pharmacol pmid:22463376
Lee CH et al. Case-crossover design: an alternative strategy for detecting drug-induced liver injury. 2012 J Clin Epidemiol pmid:22445086
Blode H et al. Evaluation of the effects of rifampicin, ketoconazole and erythromycin on the steady-state pharmacokinetics of the components of a novel oral contraceptive containing estradiol valerate and dienogest in healthy postmenopausal women. 2012 Contraception pmid:22445438
Constable PD et al. Evidence-based use of prokinetic drugs for abomasal disorders in cattle. 2012 Vet. Clin. North Am. Food Anim. Pract. pmid:22374117
Mehra T et al. Treatment of severe acne with low-dose isotretinoin. 2012 Acta Derm. Venereol. pmid:22377969
Ogawa W et al. Functional study of the novel multidrug efflux pump KexD from Klebsiella pneumoniae. 2012 Gene pmid:22391093
El-Adawy H et al. Determination of antimicrobial sensitivities of Campylobacter jejuni isolated from commercial turkey farms in Germany. 2012 Avian Dis. pmid:23397839
Mercer BM et al. The antibiotic treatment of PPROM study: systemic maternal and fetal markers and perinatal outcomes. 2012 Am. J. Obstet. Gynecol. pmid:22000668
Pendela M et al. Combined use of liquid chromatography with mass spectrometry and nuclear magnetic resonance for the identification of degradation compounds in an erythromycin formulation. 2012 Anal Bioanal Chem pmid:22002558
Wilson BB et al. An atypical presentation of erythrasma. 2012 J. Am. Acad. Dermatol. pmid:23062922
Zhou L et al. Molecular characteristics of erythromycin-resistant Streptococcus pneumoniae from pediatric patients younger than five years in Beijing, 2010. 2012 BMC Microbiol. pmid:23043378
Cannon JA et al. Preoperative oral antibiotics reduce surgical site infection following elective colorectal resections. 2012 Dis. Colon Rectum pmid:23044677
Kaul M et al. A bactericidal guanidinomethyl biaryl that alters the dynamics of bacterial FtsZ polymerization. 2012 J. Med. Chem. pmid:23050700
Weisman LE et al. Appropriate antibiotic therapy improves Ureaplasma sepsis outcome in the neonatal mouse. 2012 Pediatr. Res. pmid:22907617
Henningsen E and Bygum A Budesonide-induced periorificial dermatitis presenting as chalazion and blepharitis. 2011 Sep-Oct Pediatr Dermatol pmid:21895758
Ezhova NM et al. [Molecularly imprinted hydrophilic polymer sorbents for selective sorption of erythromycin]. 2011 Nov-Dec Prikl. Biokhim. Mikrobiol. pmid:22288199
Stang EM and White MC On the macrocyclization of the erythromycin core: preorganization is not required. 2011 Angew. Chem. Int. Ed. Engl. pmid:21344559
Qin SS et al. Antimicrobial resistance in Campylobacter coli isolated from pigs in two provinces of China. 2011 Int. J. Food Microbiol. pmid:21349598
Song M et al. Antibiotic susceptibility of Propionibacterium acnes isolated from acne vulgaris in Korea. 2011 J. Dermatol. pmid:21352337
Liu BY et al. Toxic effects of erythromycin, ciprofloxacin and sulfamethoxazole on photosynthetic apparatus in Selenastrum capricornutum. 2011 Ecotoxicol. Environ. Saf. pmid:21353704
Ridley EJ and Davies AR Practicalities of nutrition support in the intensive care unit: the usefulness of gastric residual volume and prokinetic agents with enteral nutrition. 2011 Nutrition pmid:21295944
Nguyen NQ et al. Plasma erythromycin concentrations predict feeding outcomes in critically ill patients with feed intolerance. 2011 Crit. Care Med. pmid:21297459
Thenmozhi R et al. Characterization of biofilms in different clinical M serotypes of Streptococcus pyogenes. 2011 J. Basic Microbiol. pmid:21298675
Tosin M et al. In vivo trapping of polyketide intermediates from an assembly line synthase using malonyl carba(dethia)-N-acetyl cysteamines. 2011 Chem. Commun. (Camb.) pmid:21301753
Mingoia M et al. Heterogeneity of Tn5253-like composite elements in clinical Streptococcus pneumoniae isolates. 2011 Antimicrob. Agents Chemother. pmid:21263055
Werner CR et al. [Unexpected complication following esophageal variceal hemorrhage - Case 2/2011]. 2011 Dtsch. Med. Wochenschr. pmid:21271486
Vadlapatla RK et al. Differential effect of P-gp and MRP2 on cellular translocation of gemifloxacin. 2011 Int J Pharm pmid:21864659
Lubell Y et al. Susceptibility of bacterial isolates from community-acquired infections in sub-Saharan Africa and Asia to macrolide antibiotics. 2011 Trop. Med. Int. Health pmid:21740488
Spigaglia P et al. Multidrug resistance in European Clostridium difficile clinical isolates. 2011 J. Antimicrob. Chemother. pmid:21771851
Jupelli M et al. Neonatal chlamydial pneumonia induces altered respiratory structure and function lasting into adult life. 2011 Lab. Invest. pmid:21769086
Clifford V et al. Variation in erythromycin and clindamycin resistance patterns between New Zealand and Australian group B streptococcus isolates. 2011 Aust N Z J Obstet Gynaecol pmid:21806568
Nielsen EI et al. Pharmacokinetic/pharmacodynamic (PK/PD) indices of antibiotics predicted by a semimechanistic PKPD model: a step toward model-based dose optimization. 2011 Antimicrob. Agents Chemother. pmid:21807983
Gardner L et al. Photochemical control of bacterial signal processing using a light-activated erythromycin. 2011 Mol Biosyst pmid:21785768
Lee HY et al. Improved precursor-directed biosynthesis in E. coli via directed evolution. 2011 J. Antibiot. pmid:21081955
Liu Y et al. The role of the 4''-hydroxyl on motilin agonist potency in the 9-dihydroerythromycin series. 2011 Bioorg. Med. Chem. Lett. pmid:21570844
Samra Z et al. Susceptibility of Ureaplasma urealyticum to tetracycline, doxycycline, erythromycin, roxithromycin, clarithromycin, azithromycin, levofloxacin and moxifloxacin. 2011 J Chemother pmid:21571622
Bistrian BR Enteral feeding: good, but not for everyone. 2011 Crit. Care Med. pmid:21613857
Bai Y et al. Meta-analysis: erythromycin before endoscopy for acute upper gastrointestinal bleeding. 2011 Aliment. Pharmacol. Ther. pmid:21615438
Drago L et al. Macrolide resistance and in vitro selection of resistance to antibiotics in Lactobacillus isolates. 2011 J. Microbiol. pmid:21887650
Liu K et al. Direct entry to erythronolides via a cyclic bis[allene]. 2011 J. Am. Chem. Soc. pmid:21894913
Öberg AI et al. β-Adrenergic inhibition of contractility in L6 skeletal muscle cells. 2011 PLoS ONE pmid:21829455
Osman M and Ghosh SK Semiparametric bayesian testing procedure for noninferiority trials with binary endpoints. 2011 J Biopharm Stat pmid:21830923
Baronsky J et al. Perfusion calorimetry in the characterization of solvates forming isomorphic desolvates. 2011 Eur J Pharm Sci pmid:21726637
Dixon-Woods M et al. Providing the results of research to participants: a mixed-method study of the benefits and challenges of a consultative approach. 2011 Clin Trials pmid:21730081
Akshay S et al. Phylogenetic sequence variations in bacterial rRNA affect species-specific susceptibility to drugs targeting protein synthesis. 2011 Antimicrob. Agents Chemother. pmid:21730122
Pannu J et al. In vitro antibacterial activity of NB-003 against Propionibacterium acnes. 2011 Antimicrob. Agents Chemother. pmid:21746943
Daram SR and Garretson R Erythromycin is preferable to metoclopramide as a prokinetic in acute upper GI bleeding. 2011 Gastrointest. Endosc. pmid:21704823
Ma X et al. Novel C-4'' modified azithromycin analogs with remarkably enhanced activity against erythromycin-resistant Streptococcus pneumoniae: the synthesis and antimicrobial evaluation. 2011 Eur J Med Chem pmid:21855183
Soehnlen MK et al. In vitro antimicrobial inhibition of Mycoplasma bovis isolates submitted to the Pennsylvania Animal Diagnostic Laboratory using flow cytometry and a broth microdilution method. 2011 J. Vet. Diagn. Invest. pmid:21908288
Albarellos GA et al. Pharmacokinetics of erythromycin after intravenous, intramuscular and oral administration to cats. 2011 Vet. J. pmid:19854664
Brodesser S and Kolter T Dihydroceramide desaturase inhibition by a cyclopropanated dihydroceramide analog in cultured keratinocytes. 2011 J Lipids pmid:21490810
Motoyama M et al. Residues of pharmaceutical products in recycled organic manure produced from sewage sludge and solid waste from livestock and relationship to their fermentation level. 2011 Chemosphere pmid:21570103
Bonofiglio L et al. Dissemination of an erythromycin-resistant penicillin-nonsusceptible Streptococcus pneumoniae Poland(6B)-20 clone in Argentina. 2011 Microb. Drug Resist. pmid:21128835
Zanoni RG et al. Occurrence of Helicobacter pullorum in turkeys. 2011 Vet. Microbiol. pmid:21144678
Altraif I et al. Effect of erythromycin before endoscopy in patients presenting with variceal bleeding: a prospective, randomized, double-blind, placebo-controlled trial. 2011 Gastrointest. Endosc. pmid:21145052
Bopp LH et al. Activities of tigecycline and comparators against Legionella pneumophila and Legionella micdadei extracellularly and in human monocyte-derived macrophages. 2011 Diagn. Microbiol. Infect. Dis. pmid:21146719
Braga TM et al. Involvement, and dissemination, of the enterococcal small multidrug resistance transporter QacZ in resistance to quaternary ammonium compounds. 2011 J. Antimicrob. Chemother. pmid:21147826
Allen VG et al. Molecular analysis of antimicrobial resistance mechanisms in Neisseria gonorrhoeae isolates from Ontario, Canada. 2011 Antimicrob. Agents Chemother. pmid:21098249
Miller E et al. Herd immunity and serotype replacement 4 years after seven-valent pneumococcal conjugate vaccination in England and Wales: an observational cohort study. 2011 Lancet Infect Dis pmid:21621466
Taillon MP et al. Potentially new isobaric metabolite of fluvastatin observed by LC-MS/MS during incurred sample analysis. 2011 Bioanalysis pmid:21877892
Koulnis M et al. Negative autoregulation by Fas stabilizes adult erythropoiesis and accelerates its stress response. 2011 PLoS ONE pmid:21760888
Feneran AN et al. Retinoid plus antimicrobial combination treatments for acne. 2011 Clin Cosmet Investig Dermatol pmid:21760743
Mueller DH et al. Constraints to implementing the Essential Health Package in Malawi. 2011 PLoS ONE pmid:21695115
Luo DQ et al. In vitro activities of erythromycin, tetracycline and levofloxacin alone and in dual combinations against ureaplasma spp. 2011 Chemotherapy pmid:21430380
Ma L et al. Green fluorescent protein labeling of Listeria, Salmonella, and Escherichia coli O157:H7 for safety-related studies. 2011 PLoS ONE pmid:21483738
Yongsheng J et al. Antitumor activity of erythromycin on human neuroblastoma cell line (SH-SY5Y). 2011 J. Huazhong Univ. Sci. Technol. Med. Sci. pmid:21336720
Pérez-Trallero E et al. In vitro activities of retapamulin and 16 other antimicrobial agents against recently obtained Streptococcus pyogenes isolates. 2011 Antimicrob. Agents Chemother. pmid:21343452
Filić D et al. Crystal structure and physicochemical properties of crystalline form of 2'-O-{3-[(7-chloro-4-quinolinyl)amino]propyl}-9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin A. 2011 J Pharm Sci pmid:21394721
van den Bosch S et al. Erythromycin to promote bedside placement of a self-propelled nasojejunal feeding tube in non-critically ill patients having pancreatitis: a randomized, double-blind, placebo-controlled study. 2011 Nutr Clin Pract pmid:21447772
Louvet JN et al. Simultaneous Gram and viability staining on activated sludge exposed to erythromycin: 3D CLSM time-lapse imaging of bacterial disintegration. 2011 Int J Hyg Environ Health pmid:21420358
Serdoz F et al. Development and pharmacokinetic evaluation of erythromycin lipidic formulations for oral administration in rainbow trout (Oncorhynchus mykiss). 2011 Eur J Pharm Biopharm pmid:21402156
Marjanović N et al. Macrolide antibiotics broadly and distinctively inhibit cytokine and chemokine production by COPD sputum cells in vitro. 2011 Pharmacol. Res. pmid:21315154
Siibak T et al. Antibiotic-induced ribosomal assembly defects result from changes in the synthesis of ribosomal proteins. 2011 Mol. Microbiol. pmid:21320180
Dow GS et al. Central nervous system exposure of next generation quinoline methanols is reduced relative to mefloquine after intravenous dosing in mice. 2011 Malar. J. pmid:21645370
Piccialli V et al. Isolation of a bis-iodurated tetra-THF as a trace product from the oxidation of squalene with RuOâ‚„ and its double ring expansion to a novel bis-THF-bis-THP compound. 2011 Molecules pmid:21709619
Wu JC and Sung JJ Pharmacologic therapy for nonvariceal upper gastrointestinal bleeding. 2011 Gastrointest. Endosc. Clin. N. Am. pmid:21944417
Kovacs TO and Jensen DM Endoscopic therapy for severe ulcer bleeding. 2011 Gastrointest. Endosc. Clin. N. Am. pmid:21944418
Ozkok IP et al. Respirometric assessment of substrate binding by antibiotics in peptone biodegradation. 2011 J Environ Sci Health A Tox Hazard Subst Environ Eng pmid:22029701
Justa RF et al. Bacillary angiomatosis in HIV-positive patient from Northeastern Brazil: a case report. 2011 Rev. Soc. Bras. Med. Trop. pmid:22031085
Jakeman DL and Sadeghi-Khomami A A β-(1,2)-glycosynthase and an attempted selection method for the directed evolution of glycosynthases. 2011 Biochemistry pmid:22035228
Zhou Y et al. [Detection and the antibiotic susceptibility analysis of mycoplasma and chlamydia in urogenital tract infections of 327 cases patients with tubal infertility]. 2011 Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi pmid:21977592
Farkas B et al. [Frequency and antibiotic resistance of Ureaplasma urealyticum and Mycoplasma hominis in genital samples of sexually active individuals]. 2011 Orv Hetil pmid:21979223
Gray KL et al. The outpatient institutional antibiogram does not accurately reflect the susceptibility of prepartum group B streptococcal isolates to erythromycin and clindamycin. 2011 Diagn. Microbiol. Infect. Dis. pmid:21982562
Sedighi I et al. Nasal carriage of methicillin resistant Staphylococcus aureus and their antibiotic susceptibility patterns in children attending day-care centers. 2011 Acta Microbiol Immunol Hung pmid:21983324
Ma X and Ma S Significant breakthroughs in search for anti-infectious agents derived from erythromycin A. 2011 Curr. Med. Chem. pmid:21517774
Boecxstaens V et al. Modulation of the postprandial acid and bile pockets at the gastro-oesophageal junction by drugs that affect gastric motility. 2011 Aliment. Pharmacol. Ther. pmid:21517922
Sugawara A et al. Novel 12-membered non-antibiotic macrolides from erythromycin A; EM900 series as novel leads for anti-inflammatory and/or immunomodulatory agents. 2011 Bioorg. Med. Chem. Lett. pmid:21524580
Cong C et al. Synthesis and antibacterial activity of novel 4″-O-benzimidazolyl clarithromycin derivatives. 2011 Eur J Med Chem pmid:21524827
Ando F et al. Synergic effects of β-estradiol and erythromycin on hERG currents. 2011 J. Membr. Biol. pmid:21484263
Flaman AS et al. The effect of interferon-α on the expression of cytochrome P450 3A4 in human hepatoma cells. 2011 Toxicol. Appl. Pharmacol. pmid:21466820
Zou LK et al. Erythromycin resistance and virulence genes in Enterococcus faecalis from swine in China. 2011 New Microbiol. pmid:21344149
Liu L et al. Disappearance of sexual dimorphism in triptolide metabolism in monosodium glutamate treated neonatal rats. 2011 Arzneimittelforschung pmid:21428244
Lee Y et al. Chemistry and biology of macrolide antiparasitic agents. 2011 J. Med. Chem. pmid:21428405
Bansal BK et al. Elimination of erythromycin in milk after intramammary administration in cows with specific mastitis: relation to dose, milking frequency and udder health. 2011 Trop Anim Health Prod pmid:20844949