erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Acneiform Eruptions D017486 3 associated lipids
Pityriasis Lichenoides D017514 2 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Lung Diseases, Interstitial D017563 5 associated lipids
Retropharyngeal Abscess D017703 2 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Limb Deformities, Congenital D017880 4 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Adrenocortical Carcinoma D018268 4 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Lymphoma, B-Cell, Marginal Zone D018442 1 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Gastroparesis D018589 2 associated lipids
Arthralgia D018771 8 associated lipids
Abdominal Abscess D018784 2 associated lipids
Sepsis D018805 11 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Postoperative Nausea and Vomiting D020250 1 associated lipids
Enterocolitis, Necrotizing D020345 3 associated lipids
Epidural Abscess D020802 1 associated lipids
Neuroaspergillosis D020953 2 associated lipids
Communicable Diseases, Emerging D021821 3 associated lipids
Pelvic Infection D034161 1 associated lipids
Acalculous Cholecystitis D042101 3 associated lipids
Ileus D045823 3 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Moraxellaceae Infections D045828 3 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Seroma D049291 2 associated lipids
Granulomatosis, Orofacial D051261 2 associated lipids
Kidney Diseases, Cystic D052177 3 associated lipids
Pneumonia, Ventilator-Associated D053717 1 associated lipids
Atrioventricular Block D054537 1 associated lipids
Acute Lung Injury D055371 33 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Occupational Injuries D060051 1 associated lipids
Vagus Nerve Injuries D061223 1 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
De Rosa R et al. [Disappearance of Streptococcus pyogenes macrolide resistance in an area of northeastern Italy: a possible link with rational long-acting macrolide consumption]. 2009 Infez Med pmid:19602920
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Sun W et al. Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China. 2009 Antimicrob. Agents Chemother. pmid:19546358
Tazumi A et al. Molecular characterization of macrolide resistance determinants [erm(B) and mef(A)] in Streptococcus pneumoniae and viridans group streptococci (VGS) isolated from adult patients with cystic fibrosis (CF). 2009 J. Antimicrob. Chemother. pmid:19584106
Orscheln RC et al. contribution of genetically restricted, methicillin-susceptible strains to the ongoing epidemic of community-acquired Staphylococcus aureus infections. 2009 Clin. Infect. Dis. pmid:19589082
Li X et al. Emerging macrolide resistance in Mycoplasma pneumoniae in children: detection and characterization of resistant isolates. 2009 Pediatr. Infect. Dis. J. pmid:19633515
Alighardashi A et al. Acute sensitivity of activated sludge bacteria to erythromycin. 2009 J. Hazard. Mater. pmid:19674840
Melnik BC et al. Anti-acne agents attenuate FGFR2 signal transduction in acne. 2009 J. Invest. Dermatol. pmid:19225542
Sadreddini S et al. A double blind, randomized, placebo controlled study to evaluate the efficacy of erythromycin in patients with knee effusion due to osteoarthritis. 2009 Int J Rheum Dis pmid:20374316
Chawengsub Y et al. Identification of 13-hydroxy-14,15-epoxyeicosatrienoic acid as an acid-stable endothelium-derived hyperpolarizing factor in rabbit arteries. 2009 J. Biol. Chem. pmid:19737933
Toomey N et al. Assessment of antimicrobial resistance transfer between lactic acid bacteria and potential foodborne pathogens using in vitro methods and mating in a food matrix. 2009 Foodborne Pathog. Dis. pmid:19799525
Siira L et al. Temporal trends of antimicrobial resistance and clonality of invasive Streptococcus pneumoniae isolates in Finland, 2002 to 2006. 2009 Antimicrob. Agents Chemother. pmid:19273677
Shah SS et al. Inhibitory effects of ketoconazole, cimetidine and erythromycin on hepatic CYP3A activities in cats. 2009 J. Vet. Med. Sci. pmid:19801894
Liu Y et al. Antimicrobial susceptibility of Mycoplasma pneumoniae isolates and molecular analysis of macrolide-resistant strains from Shanghai, China. 2009 Antimicrob. Agents Chemother. pmid:19273684
Xin D et al. Molecular mechanisms of macrolide resistance in clinical isolates of Mycoplasma pneumoniae from China. 2009 Antimicrob. Agents Chemother. pmid:19273685
Kelmer G et al. Evaluation of indwelling intravenous catheters for the regional perfusion of the limbs of horses. 2009 Vet. Rec. pmid:19855112
Donnellan F et al. Avoiding errors with intravenous erythromycin administration. 2009 Eur. J. Intern. Med. pmid:19237080
Mirza S et al. Crystal morphology engineering of pharmaceutical solids: tabletting performance enhancement. 2009 AAPS PharmSciTech pmid:19184449
Princivalli MS et al. Lactobacillus rhamnosus GG inhibits invasion of cultured human respiratory cells by prtF1-positive macrolide-resistant group A streptococci. 2009 Lett. Appl. Microbiol. pmid:19187508
Nakao K et al. Susceptibilities of 23 Desulfovibrio isolates from humans. 2009 Antimicrob. Agents Chemother. pmid:19786606
Kouvela EC et al. Distinct mode of interaction of a novel ketolide antibiotic that displays enhanced antimicrobial activity. 2009 Antimicrob. Agents Chemother. pmid:19164155
Kim BS et al. Case of minocycline-effective confluent and reticulated papillomatosis with unusual location on forehead. 2009 J. Dermatol. pmid:19348668
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Jeon B and Zhang Q Sensitization of Campylobacter jejuni to fluoroquinolone and macrolide antibiotics by antisense inhibition of the CmeABC multidrug efflux transporter. 2009 J. Antimicrob. Chemother. pmid:19279049
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Bukvić Krajacić M et al. Novel ureas and thioureas of 15-membered azalides with antibacterial activity against key respiratory pathogens. 2009 Eur J Med Chem pmid:19303171
Ng PC Use of oral erythromycin for the treatment of gastrointestinal dysmotility in preterm infants. 2009 Neonatology pmid:19218823
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Ren W et al. Effect of oral erythromycin therapy in patients with aseptic loosening of joint prostheses. 2009 Bone pmid:19154802
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Liu Y et al. Molecular evidence for spread of two major methicillin-resistant Staphylococcus aureus clones with a unique geographic distribution in Chinese hospitals. 2009 Antimicrob. Agents Chemother. pmid:19029328
Siibak T et al. Erythromycin- and chloramphenicol-induced ribosomal assembly defects are secondary effects of protein synthesis inhibition. 2009 Antimicrob. Agents Chemother. pmid:19029332
Kelly MP et al. Developmental etiology for neuroanatomical and cognitive deficits in mice overexpressing Galphas, a G-protein subunit genetically linked to schizophrenia. 2009 Mol. Psychiatry pmid:19030002
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Hariharan S et al. Enhanced corneal absorption of erythromycin by modulating P-glycoprotein and MRP mediated efflux with corticosteroids. 2009 Pharm. Res. pmid:18958406
Asmah N et al. Prevalence of erythromycin and clindamycin resistance among clinical isolates of the Streptococcus anginosus group in Germany. 2009 J. Med. Microbiol. pmid:19141740
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Bohlin C et al. Oxidation of the erythro and threo forms of the phenolic lignin model compound 1-(4-hydroxy-3-methoxyphenyl)-2-(2-methoxyphenoxy)-1,3-propanediol by laccases and model oxidants. 2009 Bioorg. Chem. pmid:19646732
Robinson TV et al. Dihydroxylation of 4-substituted 1,2-dioxines: a concise route to branched erythro sugars. 2009 J. Org. Chem. pmid:19588997
Du Y and He Q [Molecular mechanism of erythromycin in the improvement of paraquat-damaged vascular endothelial cell barrier function]. 2009 Sichuan Da Xue Xue Bao Yi Xue Ban pmid:20067116
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