erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Clark MJ et al. | Erythromycin derivatives ABT 229 and GM 611 act on motilin receptors in the rabbit duodenum. | 1999 | Clin. Exp. Pharmacol. Physiol. | pmid:10081621 |
Horn S et al. | Cholestasis and liver cell damage due to hypersensitivity to erythromycin stearate--recurrence following therapy with erythromycin succinate. | 1999 | Wien. Klin. Wochenschr. | pmid:10081126 |
DiBaise JK and Quigley EM | Efficacy of prolonged administration of intravenous erythromycin in an ambulatory setting as treatment of severe gastroparesis: one center's experience. | 1999 | J. Clin. Gastroenterol. | pmid:10078820 |
Periti P and Mazzei T | Clarithromycin: pharmacokinetic and pharmacodynamic interrelationships and dosage regimen. | 1999 | J Chemother | pmid:10078776 |
Collard JM et al. | Erythromycin enhances early postoperative contractility of the denervated whole stomach as an esophageal substitute. | 1999 | Ann. Surg. | pmid:10077045 |
Cline MS et al. | Bacillary angiomatosis in a renal transplant recipient. | 1999 | Transplantation | pmid:10075597 |
Hsueh PR et al. | Extremely high incidence of macrolide and trimethoprim-sulfamethoxazole resistance among clinical isolates of Streptococcus pneumoniae in Taiwan. | 1999 | J. Clin. Microbiol. | pmid:10074498 |
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Manna PK and Basu SK | Studies of erythromycin maltobionate, a new derivative of erythromycin. | 1999 | Drug Dev Ind Pharm | pmid:10071836 |
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Furness JB et al. | An action of erythromycin in the intestine that is not mediated via motilin receptors. | 1999 | Clin. Exp. Pharmacol. Physiol. | pmid:10065328 |
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Miyajima M et al. | Effects of erythromycin on experimental extrinsic allergic alveolitis. | 1999 | Clin. Exp. Allergy | pmid:10051731 |
McDaniel R et al. | Multiple genetic modifications of the erythromycin polyketide synthase to produce a library of novel "unnatural" natural products. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10051557 |
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Anandatheerthavarada HK et al. | Physiological role of the N-terminal processed P4501A1 targeted to mitochondria in erythromycin metabolism and reversal of erythromycin-mediated inhibition of mitochondrial protein synthesis. | 1999 | J. Biol. Chem. | pmid:10037757 |
Criteria and techniques for the diagnosis of early syphilis-revised recommended treatment schedules. | 1976 | J Iowa Med Soc | pmid:1003017 |