erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Acneiform Eruptions D017486 3 associated lipids
Pityriasis Lichenoides D017514 2 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Lung Diseases, Interstitial D017563 5 associated lipids
Retropharyngeal Abscess D017703 2 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Granuloma, Pyogenic D017789 2 associated lipids
Limb Deformities, Congenital D017880 4 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Adrenocortical Carcinoma D018268 4 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Lymphoma, B-Cell, Marginal Zone D018442 1 associated lipids
Ventricular Dysfunction, Left D018487 33 associated lipids
Gastroparesis D018589 2 associated lipids
Arthralgia D018771 8 associated lipids
Abdominal Abscess D018784 2 associated lipids
Sepsis D018805 11 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
Dermatitis, Perioral D019557 4 associated lipids
Postoperative Nausea and Vomiting D020250 1 associated lipids
Enterocolitis, Necrotizing D020345 3 associated lipids
Epidural Abscess D020802 1 associated lipids
Neuroaspergillosis D020953 2 associated lipids
Communicable Diseases, Emerging D021821 3 associated lipids
Pelvic Infection D034161 1 associated lipids
Acalculous Cholecystitis D042101 3 associated lipids
Ileus D045823 3 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Moraxellaceae Infections D045828 3 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Seroma D049291 2 associated lipids
Granulomatosis, Orofacial D051261 2 associated lipids
Kidney Diseases, Cystic D052177 3 associated lipids
Pneumonia, Ventilator-Associated D053717 1 associated lipids
Atrioventricular Block D054537 1 associated lipids
Acute Lung Injury D055371 33 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Occupational Injuries D060051 1 associated lipids
Vagus Nerve Injuries D061223 1 associated lipids
Drug-Related Side Effects and Adverse Reactions D064420 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
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Sugiyama Y et al. [Changes in cytokine production by pulmonary alveolar macrophages collected from rats that have been treated with erythromycin for an extended period]. 1998 Jpn J Antibiot pmid:9597506
Abe S et al. [Effect of macrolides on IL-8 gene expression by cultured airway epithelial cells]. 1998 Jpn J Antibiot pmid:9597504
Nishimura J et al. [Effects of erythromycin on Pseudomonas aeruginosa pyocyanine-induced IL-8 production and its biological activity (the 2nd report)]. 1998 Jpn J Antibiot pmid:9597503
Okura M et al. [Multicenter study on clinical effects of a small dose of erythromycin on chronic lung disorders of premature infants--single blind comparison of treated and untreated groups. A committee for the Study of EM Therapy for Chronic Lung Diseases of Premature Infants]. 1998 Jpn J Antibiot pmid:9597500
Miyazawa T et al. [Mucous pathology and macrolide treatment of paranasal sinusitis in children]. 1998 Jpn J Antibiot pmid:9597499
Kishi K et al. [Study of efficacy of macrolide therapy applied to Kartagener's syndrome]. 1998 Jpn J Antibiot pmid:9597497
Shirai R et al. [Evaluation of the duration of medication with erythromycin for treatment of diffuse panbronchitis--a comparison between interruption of medication and continued administration]. 1998 Jpn J Antibiot pmid:9597496
Nakada K et al. [Therapeutic guideline for diffuse panbronchitis (draft). Subcommittee on Diffuse Lung Diseases, Research Committee on Respiratory Diseases Organized by the Ministry of Health and Welfare]. 1998 Jpn J Antibiot pmid:9597494
Kawasaki S et al. [Effects of a steroid and macrolide antibiotic on adhesion of neutrophils to the airway epithelial cells]. 1998 Jpn J Antibiot pmid:9597483
Takeda H et al. [Bone absorption suppression by broad spectrum antibiotics]. 1998 Jpn J Antibiot pmid:9597475
Tamaoki J et al. [Effects of macrolide antibiotics on iNOS gene expression and NO production by alveolar macrophages]. 1998 Jpn J Antibiot pmid:9597474
Hikariyama T et al. [Study of suppression of neutrophil functions and prevention of vascular endothelial injury by macrolide antibiotics]. 1998 Jpn J Antibiot pmid:9597473
Hori S et al. [Effects of macrolide drugs on endogenous glucocorticoids]. 1997 Jpn J Antibiot pmid:9597471
Nonaka M et al. [Effects of macrolide antibiotics on fibroblasts]. 1997 Jpn J Antibiot pmid:9597470
Miyashima S et al. [Effects of erythromycin on a mouse hypersensitivity pneumonia model]. 1997 Jpn J Antibiot pmid:9597469
Kaseta M et al. [Study of therapeutic effects of macrolide antibiotics on patients with anti-HTLV-1 antibody positive DPB (diffuse panbronchitis)]. 1997 Jpn J Antibiot pmid:9597466
Takada T et al. [Study of specific mRNA expression by peripheral monocytes of patients with diffuse panbronchitis using cDNA representational difference analysis (RDA)]. 1997 Jpn J Antibiot pmid:9597465
Hoshina S et al. [C kinase activation and induction of HL 60 promyelocytic leukemia cell differentiation caused by roxithromycin]. 1997 Jpn J Antibiot pmid:9597464
Tei A et al. [Effects and actions of EM (erythromycin), CAM (clarithromycin), and JM (josamycin) on IL-4 and IL-5 production by monocytes]. 1997 Jpn J Antibiot pmid:9597458
Kudo S [Preliminary survey on DPB (diffuse panbronchitis) in Japan and a survey on the status of DPB in China]. 1997 Jpn J Antibiot pmid:9597457
Kondo K et al. [Quantitative evaluation of the inhibitory action of macrolide antibiotics on biofilm formation by Pseudomonas aeruginosa]. 1997 Jpn J Antibiot pmid:9597456
Kobayashi O et al. [Actions of macrolide antibiotics on alginate production by Pseudomonas aeruginosa]. 1997 Jpn J Antibiot pmid:9597455
Ohara K et al. [Effects of pretreatment by erythromycin or rokitamycin on aminoglycoside inactivating enzyme of Pseudomonas aeruginosa]. 1997 Jpn J Antibiot pmid:9597454
Sato K et al. [Pyocyanine synthesis by Pseudomonas aeruginosa in chronic airway infection and the effect of erythromycin on its biological activity]. 1997 Jpn J Antibiot pmid:9597453
Mineshita M et al. [Effect of macrolide antibiotics on actin polymerization reactions of neutrophils]. 1997 Jpn J Antibiot pmid:9597447
Kawasaki S et al. [Effects of a steroid and macrolide antibiotic on IL-8 production by neutrophils]. 1997 Jpn J Antibiot pmid:9597446
Suzuki H et al. [Il-8 secretion by cultured epithelial cells of human nasal mucosa and its suppression by macrolide antibiotics]. 1997 Jpn J Antibiot pmid:9597442
Nakada J et al. [Effects of erythromycin and roxithromycin on airway goblet cell secretion]. 1997 Jpn J Antibiot pmid:9597441
Ieshiro R et al. [Effect of clarithromycin in extending the life expectancy of patients with non-small-cell lung cancer]. 1997 Jpn J Antibiot pmid:9597440
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Bassotti G et al. Effect of different doses of erythromycin on colonic motility in patients with slow transit constipation. 1998 Z Gastroenterol pmid:9577904
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Higa F et al. Simplified quantitative assay system for measuring activities of drugs against intracellular Legionella pneumophila. 1998 J. Clin. Microbiol. pmid:9574712
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Juanqin G et al. Evaluation of the effectiveness of childhood generalized pustular psoriasis treatment in 30 cases. 1998 Mar-Apr Pediatr Dermatol pmid:9572705
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Andrews PA Interactions with ciprofloxacin and erythromycin leading to aminophylline toxicity. 1998 Nephrol. Dial. Transplant. pmid:9568870
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Salah-Bey K et al. Targeted gene inactivation for the elucidation of deoxysugar biosynthesis in the erythromycin producer Saccharopolyspora erythraea. 1998 Mol. Gen. Genet. pmid:9563840
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Garcia-Bermejo I et al. Emergence of erythromycin-resistant, clindamycin-susceptible Streptococcus pyogenes isolates in Madrid, Spain. 1998 Antimicrob. Agents Chemother. pmid:9559831
Hoppe JE and Bryskier A In vitro susceptibilities of Bordetella pertussis and Bordetella parapertussis to two ketolides (HMR 3004 and HMR 3647), four macrolides (azithromycin, clarithromycin, erythromycin A, and roxithromycin), and two ansamycins (rifampin and rifapentine). 1998 Antimicrob. Agents Chemother. pmid:9559823
Roblin PM and Hammerschlag MR In vitro activity of a new 8-methoxyquinolone, BAY 12-8039, against Chlamydia pneumoniae. 1998 Antimicrob. Agents Chemother. pmid:9559818
Barry AL et al. Antipneumococcal activities of a ketolide (HMR 3647), a streptogramin (quinupristin-dalfopristin), a macrolide (erythromycin), and a lincosamide (clindamycin). 1998 Antimicrob. Agents Chemother. pmid:9559816
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Ross JI et al. Resistance to erythromycin and clindamycin in cutaneous propionibacteria is associated with mutations in 23S rRNA. 1998 Dermatology (Basel) pmid:9557230
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