erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Blattner C et al. | A case of bacillary angiomatosis in a patient with pancreatic adenocarcinoma. | 2014 | J. Cutan. Pathol. | pmid:24588271 |
Barbosa TM et al. | A novel erythromycin resistance plasmid from Bacillus sp. strain HS24, isolated from the marine sponge Haliclona simulans. | 2014 | PLoS ONE | pmid:25548909 |
Leirós M et al. | Mitigation of ROS insults by Streptomyces secondary metabolites in primary cortical neurons. | 2014 | ACS Chem Neurosci | pmid:24219236 |
Farley R et al. | Antibiotics for bronchiolitis in children under two years of age. | 2014 | Cochrane Database Syst Rev | pmid:25300167 |
Farabella I et al. | Allosteric signalling in the outer membrane translocation domain of PapC usher. | 2014 | Elife | pmid:25271373 |
Jaiswal N et al. | Distribution of serotypes, vaccine coverage, and antimicrobial susceptibility pattern of Streptococcus pneumoniae in children living in SAARC countries: a systematic review. | 2014 | PLoS ONE | pmid:25268974 |
Katayama Y et al. | Neuroprotective effects of erythromycin on cerebral ischemia reperfusion-injury and cell viability after oxygen-glucose deprivation in cultured neuronal cells. | 2014 | Brain Res. | pmid:25264351 |
Hoover WD et al. | Topical antibiotic monotherapy prescribing practices in acne vulgaris. | 2014 | J Dermatolog Treat | pmid:24171409 |
Shen Y et al. | Mitigative effect of erythromycin on PMMA challenged preosteoblastic MC3T3-E1 cells. | 2014 | ScientificWorldJournal | pmid:25110723 |
Tagawa J et al. | Development of a novel plasmid vector pTIO-1 adapted for electrotransformation of Porphyromonas gingivalis. | 2014 | J. Microbiol. Methods | pmid:25102110 |
Serna-Tamayo C et al. | Neonatal and infantile acne vulgaris: an update. | 2014 | Cutis | pmid:25101339 |
Kawaguchiya M et al. | Serotype distribution and susceptibility to penicillin and erythromycin among noninvasive or colonization isolates of Streptococcus pneumoniae in northern Japan: a cross-sectional study in the pre-PCV7 routine immunization period. | 2014 | Microb. Drug Resist. | pmid:24766085 |
Gaudreau C et al. | Antimicrobial susceptibility of Campylobacter jejuni and Campylobacter coli isolates obtained in Montreal, Quebec, Canada, from 2002 to 2013. | 2014 | J. Clin. Microbiol. | pmid:24759726 |
Boleda MR et al. | Survey of the occurrence of pharmaceuticals in Spanish finished drinking waters. | 2014 | Environ Sci Pollut Res Int | pmid:24756682 |
Zheng PX et al. | Arrangement and number of clustered regularly interspaced short palindromic repeat spacers are associated with erythromycin susceptibility in emm12, emm75 and emm92 of group A streptococcus. | 2014 | Clin. Microbiol. Infect. | pmid:24118239 |
Singh P et al. | Erythromycin-induced genotoxicity and hepatotoxicity in mice pups treated during prenatal and postnatal period. | 2014 | Fundam Clin Pharmacol | pmid:24117516 |
Dalbøge CS et al. | Pharmacokinetic variability of clarithromycin and differences in CYP3A4 activity in patients with cystic fibrosis. | 2014 | J. Cyst. Fibros. | pmid:24035278 |
Kim S and Muthusamy VR | Prophylactic erythromycin in acute upper gastrointestinal bleeding: moving forward in improving endoscopic efficacy. | 2013 Sep-Oct | Saudi J Gastroenterol | pmid:24045591 |
Theivanayagam S et al. | Administration of erythromycin before endoscopy in upper gastrointestinal bleeding: a meta-analysis of randomized controlled trials. | 2013 Sep-Oct | Saudi J Gastroenterol | pmid:24045593 |
Manchia M et al. | Repeated erythromycin/codeine-induced psychotic mania. | 2013 Sep-Oct | Clin Neuropharmacol | pmid:24045612 |
De Alwis HG et al. | Determination of erythromycin in medicated salmonid fish feed by liquid chromatography and UV spectroscopy. | 2013 Nov-Dec | J AOAC Int | pmid:24645499 |
Zou X et al. | Biochemical parameters of Saccharopolyspora erythraea during feeding ammonium sulphate in erythromycin biosynthesis phase. | 2013 Mar-Apr | Prikl. Biokhim. Mikrobiol. | pmid:23795479 |
Jiang M et al. | Improved heterologous erythromycin A production through expression plasmid re-design. | 2013 Jul-Aug | Biotechnol. Prog. | pmid:23804312 |
Lynch M et al. | Bullae of the hands, feet, and perioral area in a 3-month-old infant. Bullous pemphigoid. | 2013 Jan-Feb | Pediatr Dermatol | pmid:23316718 |
Litvinchuk AV et al. | Mitochondrially-encoded protein Var1 promotes loss of respiratory function in Saccharomyces cerevisiae under stressful conditions. | 2013 Apr-May | Eur. J. Cell Biol. | pmid:23523087 |
Palmieri C et al. | Interspecies mobilization of an ermT-carrying plasmid of Streptococcus dysgalactiae subsp. equisimilis by a coresident ICE of the ICESa2603 family. | 2013 | J. Antimicrob. Chemother. | pmid:22949621 |
Guan Y et al. | [Effect of combination of sub-MIC sodium houttuyfonate and erythromycin on biofilm of Staphylococcus epidermidis]. | 2013 | Zhongguo Zhong Yao Za Zhi | pmid:23724685 |
Lanzarotti C and Rossi G | Effect of netupitant, a highly selective NKâ‚ receptor antagonist, on the pharmacokinetics of midazolam, erythromycin, and dexamethasone. | 2013 | Support Care Cancer | pmid:23729226 |
Nemeghaire S et al. | Characterization of methicillin-resistant Staphylococcus aureus from healthy carrier chickens. | 2013 | Avian Pathol. | pmid:23777220 |
Patel AM et al. | Statin toxicity from macrolide antibiotic coprescription: a population-based cohort study. | 2013 | Ann. Intern. Med. | pmid:23778904 |
Wasels F et al. | Clostridium difficile erm(B)-containing elements and the burden on the in vitro fitness. | 2013 | J. Med. Microbiol. | pmid:23741023 |
Kawai Y et al. | Nationwide surveillance of macrolide-resistant Mycoplasma pneumoniae infection in pediatric patients. | 2013 | Antimicrob. Agents Chemother. | pmid:23716043 |
Yun SH et al. | Demodex folliculitis presenting as periocular vesiculopustular rash. | 2013 | Orbit | pmid:23895342 |
González-Hein G et al. | [Molecular analysis of fluoroquinolones and macrolides resistance in Campylobacter jejuni isolates from humans, bovine and chicken meat]. | 2013 | Rev Chilena Infectol | pmid:23677151 |
Adhikari MD et al. | Membrane-directed high bactericidal activity of (gold nanoparticle)-polythiophene composite for niche applications against pathogenic bacteria. | 2013 | Adv Healthc Mater | pmid:23184755 |
Utsunomiya S et al. | Critical residues in the transmembrane helical bundle domains of the human motilin receptor for erythromycin binding and activity. | 2013 | Regul. Pept. | pmid:23142315 |
Li YJ et al. | EM, EM703 inhibit NF-kB activation induced by oxidative stress from diesel exhaust particle in human bronchial epithelial cells: importance in IL-8 transcription. | 2013 | Pulm Pharmacol Ther | pmid:23291319 |
Derrouiche S et al. | Process design for wastewater treatment: catalytic ozonation of organic pollutants. | 2013 | Water Sci. Technol. | pmid:24056437 |
Jiang M et al. | Deoxysugar pathway interchange for erythromycin analogues heterologously produced through Escherichia coli. | 2013 | Metab. Eng. | pmid:24060454 |
Gold RM and Lawhon SD | Incidence of inducible clindamycin resistance in Staphylococcus pseudintermedius from dogs. | 2013 | J. Clin. Microbiol. | pmid:24025915 |
Henson AM et al. | Detection of Streptococcus pyogenes by use of Illumigene group A Streptococcus assay. | 2013 | J. Clin. Microbiol. | pmid:24048538 |
Wieczorek K et al. | Prevalence and antimicrobial resistance of Campylobacter spp. isolated from poultry carcasses in Poland. | 2013 | J. Food Prot. | pmid:23905805 |
Di Salvo A et al. | Pharmacokinetics and residue depletion of erythromycin in rainbow trout Oncorhynchus mykiss (Walbaum). | 2013 | J. Fish Dis. | pmid:24118016 |
Avci O et al. | A comparison between the effectiveness of erythromycin, single-dose clarithromycin and topical fusidic acid in the treatment of erythrasma. | 2013 | J Dermatolog Treat | pmid:21923567 |
Link-Gelles R et al. | Geographic and temporal trends in antimicrobial nonsusceptibility in Streptococcus pneumoniae in the post-vaccine era in the United States. | 2013 | J. Infect. Dis. | pmid:23852588 |
Pohl O et al. | Effects of erythromycin at steady-state concentrations on the pharmacokinetics of ulipristal acetate. | 2013 | J Clin Pharm Ther | pmid:24102384 |
Kelley C et al. | Antimicrobial activity of various 4- and 5-substituted 1-phenylnaphthalenes. | 2013 | Eur J Med Chem | pmid:23314053 |
Novy P et al. | Synergistic interactions of epigallocatechin gallate and oxytetracycline against various drug resistant Staphylococcus aureus strains in vitro. | 2013 | Phytomedicine | pmid:23485046 |
Panditi VR et al. | Online solid-phase extraction-liquid chromatography-electrospray-tandem mass spectrometry determination of multiple classes of antibiotics in environmental and treated waters. | 2013 | Anal Bioanal Chem | pmid:23494277 |
Kwak HM et al. | The efficacy of cefazolin plus macrolide (erythromycin or clarithromycin) versus cefazolin alone in neonatal morbidity and placental inflammation for women with preterm premature rupture of membranes. | 2013 | Placenta | pmid:23465535 |
Desroy N et al. | Novel HldE-K inhibitors leading to attenuated Gram negative bacterial virulence. | 2013 | J. Med. Chem. | pmid:23409840 |
Magee TV et al. | Novel 3-O-carbamoyl erythromycin A derivatives (carbamolides) with activity against resistant staphylococcal and streptococcal isolates. | 2013 | Bioorg. Med. Chem. Lett. | pmid:23414806 |
Lermite E et al. | Complications after pancreatic resection: diagnosis, prevention and management. | 2013 | Clin Res Hepatol Gastroenterol | pmid:23415988 |
Atamanyuk D et al. | Vectorization efforts to increase Gram-negative intracellular drug concentration: a case study on HldE-K inhibitors. | 2013 | J. Med. Chem. | pmid:23445125 |
Gomes DL et al. | SubMICs of penicillin and erythromycin enhance biofilm formation and hydrophobicity of Corynebacterium diphtheriae strains. | 2013 | J. Med. Microbiol. | pmid:23449875 |
Yang M et al. | Macrolides for diffuse panbronchiolitis. | 2013 | Cochrane Database Syst Rev | pmid:23450579 |
Katipoglu-Yazan T et al. | Acute impact of erythromycin and tetracycline on the kinetics of nitrification and organic carbon removal in mixed microbial culture. | 2013 | Bioresour. Technol. | pmid:23892149 |
Schafer F et al. | Antimicrobial susceptibility and genetic characteristics of Propionibacterium acnes isolated from patients with acne. | 2013 | Int. J. Dermatol. | pmid:23432195 |
Liu JF et al. | [Effect of erythromycin on electrical activity and gastric emptying of the intrathoracic stomach after esophagectomy for esophageal cancer]. | 2013 | Zhonghua Wei Chang Wai Ke Za Zhi | pmid:24061999 |
Chen Y et al. | Significant decrease of broth viscosity and glucose consumption in erythromycin fermentation by dynamic regulation of ammonium sulfate and phosphate. | 2013 | Bioresour. Technol. | pmid:23500575 |
Hahn A et al. | The outer membrane TolC-like channel HgdD is part of tripartite resistance-nodulation-cell division (RND) efflux systems conferring multiple-drug resistance in the Cyanobacterium Anabaena sp. PCC7120. | 2013 | J. Biol. Chem. | pmid:24014018 |
Whitehead TR and Cotta MA | Stored swine manure and swine faeces as reservoirs of antibiotic resistance genes. | 2013 | Lett. Appl. Microbiol. | pmid:23297734 |
Basak R and Bandyopadhyay R | Encapsulation of hydrophobic drugs in Pluronic F127 micelles: effects of drug hydrophobicity, solution temperature, and pH. | 2013 | Langmuir | pmid:23472840 |
Yang J et al. | Characterization of chicken cytochrome P450 1A4 and 1A5: inter-paralog comparisons of substrate preference and inhibitor selectivity. | 2013 | Comp. Biochem. Physiol. C Toxicol. Pharmacol. | pmid:23474502 |
Capanna F et al. | Antibiotic resistance patterns among group B Streptococcus isolates: implications for antibiotic prophylaxis for early-onset neonatal sepsis. | 2013 | Swiss Med Wkly | pmid:23572445 |
Yadav DK et al. | Failure of secondary prophylaxis with erythromycin in rheumatic heart disease. | 2013 | Indian Pediatr | pmid:24382905 |
Yang X et al. | Occurrence and fate of PPCPs and correlations with water quality parameters in urban riverine waters of the Pearl River Delta, South China. | 2013 | Environ Sci Pollut Res Int | pmid:23608973 |
Ferrieri P et al. | Serotype IV and invasive group B Streptococcus disease in neonates, Minnesota, USA, 2000-2010. | 2013 | Emerging Infect. Dis. | pmid:23628320 |
Chen Y et al. | Controlling the feed rate of glucose and propanol for the enhancement of erythromycin production and exploration of propanol metabolism fate by quantitative metabolic flux analysis. | 2013 | Bioprocess Biosyst Eng | pmid:23361182 |
Chang YC and Lo HH | Identification, clinical aspects, susceptibility pattern, and molecular epidemiology of beta-haemolytic group G Streptococcus anginosus group isolates from central Taiwan. | 2013 | Diagn. Microbiol. Infect. Dis. | pmid:23632249 |
Melnik BC and Schmitz G | Are therapeutic effects of antiacne agents mediated by activation of FoxO1 and inhibition of mTORC1? | 2013 | Exp. Dermatol. | pmid:23800068 |
Müller M et al. | The absolute configuration of (+)- and (-)-erythro-mefloquine. | 2013 | Angew. Chem. Int. Ed. Engl. | pmid:23616269 |
Gaudreau C et al. | Campylobacter coli outbreak in men who have sex with men, Quebec, Canada, 2010-2011. | 2013 | Emerging Infect. Dis. | pmid:23647786 |
Kjær S et al. | Ultrasound-guided drainage of subcutaneous abscesses on the trunk is feasible. | 2013 | Dan Med J | pmid:23651712 |
Ragazzi E et al. | Saliva concentration of amoxicillin, erythromycin, and ciprofloxacin in outpatients: a comparison between the young and the elderly. | 2013 | J Chemother | pmid:23684362 |
Rasamiravaka T et al. | Evaluation of methicillin-resistant Staphylococcus aureus nasal carriage in Malagasy patients. | 2013 | J Infect Dev Ctries | pmid:23592641 |
Nakajima T et al. | Absence of intervening sequences and point mutations in the V domain within 23S rRNA in Campylobacter lari isolates. | 2013 | Folia Microbiol. (Praha) | pmid:23595231 |
Ma X et al. | Characterization of erythromycin-resistant Streptococcus pneumoniae isolates causing invasive diseases in Chinese children. | 2013 | Chin. Med. J. | pmid:23595388 |
Hinarejos P et al. | The use of erythromycin and colistin-loaded cement in total knee arthroplasty does not reduce the incidence of infection: a prospective randomized study in 3000 knees. | 2013 | J Bone Joint Surg Am | pmid:23636182 |
Fysal N et al. | Antibiogram pattern of oral microflora in periodontic children of age group 6 to 12 years: a clinicomicrobiological study. | 2013 | J Contemp Dent Pract | pmid:24309334 |
Gao X et al. | Total synthesis of 6-deoxyerythronolide B via C-C bond-forming transfer hydrogenation. | 2013 | J. Am. Chem. Soc. | pmid:23464668 |
Roberts DW | What is the role of antibiotic-containing cement in total knee arthroplasty? | 2013 | J Bone Joint Surg Am | pmid:23636201 |
Secka O et al. | Antimicrobial susceptibility and resistance patterns among Helicobacter pylori strains from The Gambia, West Africa. | 2013 | Antimicrob. Agents Chemother. | pmid:23263004 |
Bruchmann J et al. | Sub-inhibitory concentrations of antibiotics and wastewater influencing biofilm formation and gene expression of multi-resistant Pseudomonas aeruginosa wastewater isolates. | 2013 | Environ Sci Pollut Res Int | pmid:23392972 |
Simoens S et al. | Preventing COPD exacerbations with macrolides: a review and budget impact analysis. | 2013 | Respir Med | pmid:23352223 |
Lim CH et al. | Effect of DA-9701 on gastric emptying in a mouse model: assessment by ¹³C-octanoic acid breath test. | 2013 | World J. Gastroenterol. | pmid:23885150 |
Jiang M et al. | The logic, experimental steps, and potential of heterologous natural product biosynthesis featuring the complex antibiotic erythromycin A produced through E. coli. | 2013 | J Vis Exp | pmid:23354010 |
Paterna A et al. | Short communication: In vitro antimicrobial susceptibility of Mycoplasma agalactiae strains isolated from dairy goats. | 2013 | J. Dairy Sci. | pmid:24035026 |
Elens L et al. | CYP3A4 intron 6 C>T SNP (CYP3A4*22) encodes lower CYP3A4 activity in cancer patients, as measured with probes midazolam and erythromycin. | 2013 | Pharmacogenomics | pmid:23327575 |
Teske L et al. | Epidemiological investigations on the possible risk of distribution of zoonotic bacteria through apparently healthy homing pigeons. | 2013 | Avian Pathol. | pmid:23930968 |
Mueck W et al. | Co-administration of rivaroxaban with drugs that share its elimination pathways: pharmacokinetic effects in healthy subjects. | 2013 | Br J Clin Pharmacol | pmid:23305158 |
Lins RX et al. | Antimicrobial resistance and virulence traits of Enterococcus faecalis from primary endodontic infections. | 2013 | J Dent | pmid:23851130 |
Gonçalves A et al. | Antimicrobial resistance in faecal enterococci and Escherichia coli isolates recovered from Iberian wolf. | 2013 | Lett. Appl. Microbiol. | pmid:23336611 |
Rożynek E et al. | Emergence of macrolide-resistant Campylobacter strains in chicken meat in Poland and the resistance mechanisms involved. | 2013 | Foodborne Pathog. Dis. | pmid:23638847 |
Grabowicz M et al. | Dominant negative lptE mutation that supports a role for LptE as a plug in the LptD barrel. | 2013 | J. Bacteriol. | pmid:23316047 |
Dubey D et al. | A report on infection dynamics of inducible clindamycin resistance of Staphylococcus aureus isolated from a teaching hospital in India. | 2013 | Asian Pac J Trop Biomed | pmid:23593595 |
Marcellin E et al. | Saccharopolyspora erythraea's genome is organised in high-order transcriptional regions mediated by targeted degradation at the metabolic switch. | 2013 | BMC Genomics | pmid:23324121 |
Romeiro FG et al. | Erythromycin versus neomycin in the treatment of hepatic encephalopathy in cirrhosis: a randomized double-blind study. | 2013 | BMC Gastroenterol | pmid:23324408 |
Cui B et al. | Differences between two clinical Staphylococcus capitis subspecies as revealed by biofilm, antibiotic resistance, and pulsed-field gel electrophoresis profiling. | 2013 | J. Clin. Microbiol. | pmid:23052315 |
Baltar F et al. | Bacterial versus archaeal origin of extracellular enzymatic activity in the Northeast Atlantic deep waters. | 2013 | Microb. Ecol. | pmid:23015014 |