erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Giovanetti E et al. | Presence of the tet(O) gene in erythromycin- and tetracycline-resistant strains of Streptococcus pyogenes and linkage with either the mef(A) or the erm(A) gene. | 2003 | Antimicrob. Agents Chemother. | pmid:12936983 |
| Cao W et al. | [Infectious distribution and resistant of Neisseria gonorrhoeae, Mycoplasma, and Chlamydia trachomatis in the chronic prostatitis]. | 2003 | Hunan Yi Ke Da Xue Xue Bao | pmid:12934372 |
| Mikasa K et al. | [The 5th report on long-term chemotherapy using erythromycin (EM) for chronic lower airway infection--cases followed over 7 years]. | 1992 | Kansenshogaku Zasshi | pmid:1293219 |
| Petkovic H et al. | A novel erythromycin, 6-desmethyl erythromycin D, made by substituting an acyltransferase domain of the erythromycin polyketide synthase. | 2003 | J. Antibiot. | pmid:12931864 |
| Ponte C et al. | Does acetaminophen interfere in the antibiotic treatment of acute otitis media caused by a penicillin-resistant pneumococcus strain? A gerbil model. | 2003 | Pediatr. Res. | pmid:12930908 |
| Bowers AK et al. | Molecular markers for rapidly identifying candidate genes in Chlamydomonas reinhardtii. Ery1 and ery2 encode chloroplast ribosomal proteins. | 2003 | Genetics | pmid:12930744 |
| Metaxa-Mariatou V et al. | Documentation of Legionella pneumophila and Mycobacterium tuberculosis co-existence in a patient with acute respiratory distress syndrome. | 2003 Jul-Aug | In Vivo | pmid:12929592 |
| Blandino G et al. | Bactericidal activity and postantibiotic effect of cefdinir (Cl 983, FK 482) against selected pathogens. | 1992 | Drugs Exp Clin Res | pmid:1292914 |
| Ergin A et al. | In vitro susceptibility, tolerance and MLS resistance phenotypes of Group C and Group G streptococci isolated in Turkey between 1995 and 2002. | 2003 | Int. J. Antimicrob. Agents | pmid:12927957 |
| Enomoto F et al. | Modulation of neutrophil adhesion to vascular endothelial cells in rat experimental otitis media treated with a macrolide. | 2003 | Auris Nasus Larynx | pmid:12927286 |
| Ioannidou S et al. | In vitro activity of telithromycin (HMR 3647) against Greek Streptococcus pyogenes and Streptococcus pneumoniae clinical isolates with different macrolide susceptibilities. | 2003 | Clin. Microbiol. Infect. | pmid:12925112 |
| Cleary JD et al. | Effects of amphotericin B and caspofungin on histamine expression. | 2003 | Pharmacotherapy | pmid:12921242 |
| Weber K | How I treat perioral dermatitis: non-compliance with the treatment guidelines. | 2003 | Dermatology (Basel) | pmid:12920383 |
| Walsh F et al. | High-level telithromycin resistance in laboratory-generated mutants of Streptococcus pneumoniae. | 2003 | J. Antimicrob. Chemother. | pmid:12917252 |
| Miyashita N et al. | In vitro activity of cethromycin, a novel antibacterial ketolide, against Chlamydia pneumoniae. | 2003 | J. Antimicrob. Chemother. | pmid:12917246 |
| Reina J et al. | Emergence of resistance to erythromycin and fluoroquinolones in thermotolerant Campylobacter strains isolated from feces 1987-1991. | 1992 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:1291314 |
| Tack J et al. | Assessment of meal induced gastric accommodation by a satiety drinking test in health and in severe functional dyspepsia. | 2003 | Gut | pmid:12912857 |
| Carletti M et al. | In vitro formation of metabolic-intermediate cytochrome P450 complexes in rabbit liver microsomes by tiamulin and various macrolides. | 2003 Jul-Aug | Vet. Res. | pmid:12911857 |
| Lemahieu WP et al. | Measurement of hepatic and intestinal CYP3A4 and PGP activity by combined po + iv [14C]erythromycin breath and urine test. | 2003 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:12909563 |
| Maravić G et al. | Alanine-scanning mutagenesis of the predicted rRNA-binding domain of ErmC' redefines the substrate-binding site and suggests a model for protein-RNA interactions. | 2003 | Nucleic Acids Res. | pmid:12907737 |
| Pearlman M | Prevention of early-onset group B streptococcal disease in newborns. | 2003 | Obstet Gynecol | pmid:12907122 |
| Hanada E et al. | Inhibitory effect of erythromycin on potassium currents in rat ventricular myocytes in comparison with disopyramide. | 2003 | J. Pharm. Pharmacol. | pmid:12906757 |
| Stratchounski LS et al. | The inventory of antibiotics in Russian home medicine cabinets. | 2003 | Clin. Infect. Dis. | pmid:12905133 |
| Hankø E et al. | Administration of drugs known to inhibit P-glycoprotein increases brain bilirubin and alters the regional distribution of bilirubin in rat brain. | 2003 | Pediatr. Res. | pmid:12904601 |
| Hu Z et al. | A specific role of the Saccharopolyspora erythraea thioesterase II gene in the function of modular polyketide synthases. | 2003 | Microbiology (Reading, Engl.) | pmid:12904561 |
| Kuijper EJ et al. | Genotypic identification of erythromycin-resistant campylobacter isolates as helicobacter species and analysis of resistance mechanism. | 2003 | J. Clin. Microbiol. | pmid:12904383 |
| Huang JQ and Xie CM | [The effects of erythromycin on the secretion of tumor necrosis factor-alpha and transforming growth factor-beta1 and expression of connexin 43 in human pleural mesothelial cells]. | 2003 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:12901826 |
| Yongge L et al. | Relationship between plasma motilin and effect of oral erythromycin on gallbladder contraction in patients of functional dyspepsia. | 2000 | Chin. Med. Sci. J. | pmid:12901646 |
| Schlüsener MP et al. | Determination of antibiotics from soil by pressurized liquid extraction and liquid chromatography-tandem mass spectrometry. | 2003 | J Chromatogr A | pmid:12899294 |
| Murli S et al. | Metabolic engineering of Escherichia coli for improved 6-deoxyerythronolide B production. | 2003 | J. Ind. Microbiol. Biotechnol. | pmid:12898389 |
| Haefeli WE et al. | Possible risk for cardiac arrhythmia related to intravenous erythromycin. | 1992 | Intensive Care Med | pmid:1289371 |
| Fietta A et al. | Uptake of flurithromycin by human polymorphonuclear phagocytes: partial characterization of the entry mechanism. | 1992 | Chemotherapy | pmid:1288969 |
| Andrews WW and Goldenberg RL | What we have learned from an antibiotic trial in fetal fibronectin positive women. | 2003 | Semin. Perinatol. | pmid:12889590 |
| Mercer BM et al. | What we have learned regarding antibiotic therapy for the reduction of infant morbidity after preterm premature rupture of the membranes. | 2003 | Semin. Perinatol. | pmid:12889589 |
| Shishkov N and Drumev D | [Possible synergic action of some drug combinations against Mycoplasma gallisepticum]. | 1975 | Vet Med Nauki | pmid:128891 |
| Portillo A et al. | Clonal diversity among erythromycin-resistant beta-haemolytic Streptococcus isolates in La Rioja, Spain. | 2003 | J. Antimicrob. Chemother. | pmid:12888595 |
| Peck KR et al. | Antimicrobials as potential adjunctive agents in the treatment of biofilm infection with Staphylococcus epidermidis. | 2003 | Chemotherapy | pmid:12886054 |
| Schmidt LE et al. | Relationship between postoperative erythromycin breath test and early morbidity in liver transplant recipients. | 2003 | Transplantation | pmid:12883193 |
| Crum NF et al. | Halting a pneumococcal pneumonia outbreak among United States Marine Corps trainees. | 2003 | Am J Prev Med | pmid:12880877 |
| Pai SR et al. | In vivo efficacy of the ketolide ABT-773 (cethromycin) against enterococci in a mouse peritonitis model. | 2003 | Antimicrob. Agents Chemother. | pmid:12878548 |
| Syrogiannopoulos GA et al. | Antimicrobial susceptibility and macrolide resistance inducibility of Streptococcus pneumoniae carrying erm(A), erm(B), or mef(A). | 2003 | Antimicrob. Agents Chemother. | pmid:12878546 |
| Vanden Boom TJ | Recent developments in the molecular genetics of the erythromycin-producing organism Saccharopolyspora erythraea. | 2000 | Adv. Appl. Microbiol. | pmid:12876795 |
| Hergenrother PJ et al. | An abiotic strategy for the enantioselective synthesis of erythromycin B. | 2003 | Angew. Chem. Int. Ed. Engl. | pmid:12876743 |
| Wolf R et al. | Sulfonamide-induced bullous hemorrhagic eruption in a patient with low prothrombin time. | 1992 | Isr. J. Med. Sci. | pmid:1286961 |
| Corrêa JC et al. | Randomized, open-label, parallel-group, multicenter study of the efficacy and tolerability of IV gatifloxacin with the option for oral stepdown gatifloxacin versus IV ceftriaxone (with or without erythromycin or clarithromycin) with the option for oral stepdown clarithromycin for treatment of patients with mild to moderate community-acquired pneumonia requiring hospitalization. | 2003 | Clin Ther | pmid:12867221 |
| Deshpande LM and Jones RN | Antagonism between penicillin and erythromycin against Streptococcus pneumoniae: does it exist? | 2003 | Diagn. Microbiol. Infect. Dis. | pmid:12867099 |
| Mirza S et al. | Influence of solvents on the variety of crystalline forms of erythromycin. | 2003 | AAPS PharmSci | pmid:12866939 |
| Frean J et al. | Susceptibility of Bacillus anthracis to eleven antimicrobial agents including novel fluoroquinolones and a ketolide. | 2003 | J. Antimicrob. Chemother. | pmid:12865385 |
| Schöni MH | Macrolide antibiotic therapy in patients with cystic fibrosis. | 2003 | Swiss Med Wkly | pmid:12861467 |
| Fisk P | An inguinal bubo caused by Mycobacterium chelonae abscessus. | 1992 Nov-Dec | Int J STD AIDS | pmid:1286124 |
| Tenson T et al. | The mechanism of action of macrolides, lincosamides and streptogramin B reveals the nascent peptide exit path in the ribosome. | 2003 | J. Mol. Biol. | pmid:12860123 |
| Bhattacharya MK et al. | Azithromycin in the treatment of cholera in children. | 2003 | Acta Paediatr. | pmid:12856976 |
| Liu H et al. | Effect of erythromycin on contractile response of uterine smooth muscle strips in non-pregnant rats. | 2003 Jan-Feb | Pol J Pharmacol | pmid:12856827 |
| Musumeci R et al. | Internalization-associated proteins among Streptococcus pyogenes isolated from asymptomatic carriers and children with pharyngitis. | 2003 | Clin. Infect. Dis. | pmid:12856208 |
| Thiele J et al. | Mixed chimerism of erythro- and megakaryopoiesis following allogeneic bone marrow transplantation. | 2003 | Acta Haematol. | pmid:12853689 |
| Burkhart CN | Reassessment of combining benzoyl peroxide with clindamycin. | 2002 | J Drugs Dermatol | pmid:12851984 |
| McGhan LJ and Merchant SN | Erythromycin ototoxicity. | 2003 | Otol. Neurotol. | pmid:12851569 |
| George RC et al. | Antibiotic-resistant pneumococci in the United Kingdom. | 1992 | Commun Dis Rep CDR Rev | pmid:1285099 |
| Iuliucci RJ et al. | Ring-chain tautomerism in solid-phase erythromycin A: evidence by solid-state NMR. | 2003 | Solid State Nucl Magn Reson | pmid:12850255 |
| Dimaraki EV and Jaffe CA | Troglitazone induces CYP3A4 activity leading to falsely abnormal dexamethasone suppression test. | 2003 | J. Clin. Endocrinol. Metab. | pmid:12843151 |
| Besier S et al. | Selection of ketolide resistance in Staphylococcus aureus. | 2003 | Int. J. Antimicrob. Agents | pmid:12842336 |
| Berisio R et al. | Structural insight into the antibiotic action of telithromycin against resistant mutants. | 2003 | J. Bacteriol. | pmid:12837804 |
| Liu JQ et al. | A novel enzyme, D-3-hydroxyaspartate aldolase from Paracoccus denitrificans IFO 13301: purification, characterization, and gene cloning. | 2003 | Appl. Microbiol. Biotechnol. | pmid:12835921 |
| Liebold K et al. | Disseminated bullous eruption with systemic reaction caused by Cimex lectularius. | 2003 | J Eur Acad Dermatol Venereol | pmid:12834463 |
| Tsuburai T et al. | [Hypogammaglobulinemia associated with thymoma (Good syndrome) similar to diffuse panbronchiolitis]. | 2003 | Nihon Kokyuki Gakkai Zasshi | pmid:12833850 |
| Ad Hoc Committee report: systemic antibiotics for treatment of acne vulgaris: efficacy and safety. | 1975 | Arch Dermatol | pmid:128326 | |
| Zhang S et al. | Preparation of monodisperse porous polymethacrylate microspheres and their application in the capillary electrochromatography of macrolide antibiotics. | 2002 | J Chromatogr A | pmid:12831197 |
| Dodhia H et al. | UK guidelines for use of erythromycin chemoprophylaxis in persons exposed to pertussis. | 2002 | J Public Health Med | pmid:12831090 |
| Gaudreau C and Michaud S | Cluster of erythromycin- and ciprofloxacin-resistant Campylobacter jejuni subsp. jejuni from 1999 to 2001 in men who have sex with men, Québec, Canada. | 2003 | Clin. Infect. Dis. | pmid:12830417 |
| Malke H et al. | Bacteriophage P13234mo-mediated intra- and intergroup transduction of antibiotic resistance among streptococci. | 1975 | Zentralbl Bakteriol Orig A | pmid:128266 |
| Katz KC et al. | Emergence of macrolide resistance in throat culture isolates of group a streptococci in Ontario, Canada, in 2001. | 2003 | Antimicrob. Agents Chemother. | pmid:12821502 |
| Wagner J et al. | Susceptibilities of Campylobacter jejuni isolates from Germany to ciprofloxacin, moxifloxacin, erythromycin, clindamycin, and tetracycline. | 2003 | Antimicrob. Agents Chemother. | pmid:12821499 |
| Bingen E et al. | Activity of telithromycin against penicillin-resistant Streptococcus pneumoniae isolates recovered from French children with invasive and noninvasive infections. | 2003 | Antimicrob. Agents Chemother. | pmid:12821495 |
| Montanari MP et al. | Phenotypic and molecular characterization of tetracycline- and erythromycin-resistant strains of Streptococcus pneumoniae. | 2003 | Antimicrob. Agents Chemother. | pmid:12821474 |
| Hsueh PR et al. | Telithromycin and quinupristin-dalfopristin resistance in clinical isolates of Streptococcus pyogenes: SMART Program 2001 Data. | 2003 | Antimicrob. Agents Chemother. | pmid:12821461 |
| Hsueh PR et al. | Telithromycin- and fluoroquinolone-resistant Streptococcus pneumoniae in Taiwan with high prevalence of resistance to macrolides and beta-lactams: SMART program 2001 data. | 2003 | Antimicrob. Agents Chemother. | pmid:12821460 |
| Marimón JM et al. | Molecular characterization of erythromycin-resistant clinical isolates of the four major antimicrobial-resistant Spanish clones of Streptococcus pneumoniae (Spain23F-1, Spain6B-2, Spain9V-3, and Spain14-5). | 2003 | Microb. Drug Resist. | pmid:12820797 |
| Bouaziz Abed A and Maherzi A | [Efficacy of erythromycin in the treatment of cyclic vomiting syndrome in children]. | 2003 | Arch Pediatr | pmid:12818786 |
| Nemoto PA et al. | Novel 12-membered ring macrolides with activity against erythromycin-resistant organisms. | 2003 | J. Antibiot. | pmid:12817813 |
| Ito K et al. | Prediction of the in vivo interaction between midazolam and macrolides based on in vitro studies using human liver microsomes. | 2003 | Drug Metab. Dispos. | pmid:12814973 |
| Evans DC et al. | Eletriptan metabolism by human hepatic CYP450 enzymes and transport by human P-glycoprotein. | 2003 | Drug Metab. Dispos. | pmid:12814962 |
| Del Vecchio F et al. | Active-site residue, domain and module swaps in modular polyketide synthases. | 2003 | J. Ind. Microbiol. Biotechnol. | pmid:12811585 |
| Drenth JP and Engels LG | Diabetic gastroparesis. A critical reappraisal of new treatment strategies. | 1992 | Drugs | pmid:1281070 |
| Moyo SR et al. | Susceptibility of Zimbabwean Streptococcus agalactiae (group B Streptococcus; GBS) isolates to four different antibiotics. | 2001 Sep-Oct | Cent Afr J Med | pmid:12808772 |
| Mendes C et al. | Antibacterial resistance of community-acquired respiratory tract pathogens recovered from patients in Latin America: results from the PROTEKT surveillance study (1999-2000). | 2003 | Braz J Infect Dis | pmid:12807691 |
| Wasas AD et al. | Correlation between erythromycin and azithromycin resistance in Streptococcus pneumoniae. | 2003 | S. Afr. Med. J. | pmid:12806721 |
| Peters DH et al. | Azithromycin. A review of its antimicrobial activity, pharmacokinetic properties and clinical efficacy. | 1992 | Drugs | pmid:1280567 |
| GarcÃa I et al. | Accumulation and activity of cethromycin (ABT-773) within human polymorphonuclear leucocytes. | 2003 | J. Antimicrob. Chemother. | pmid:12805263 |
| Acikgoz ZC et al. | Macrolide resistance determinants of group A streptococci in Ankara, Turkey. | 2003 | J. Antimicrob. Chemother. | pmid:12805256 |
| Morosini MI et al. | Streptococcus pyogenes isolates with characterized macrolide resistance mechanisms in Spain: in vitro activities of telithromycin and cethromycin. | 2003 | J. Antimicrob. Chemother. | pmid:12805254 |
| Salvat C et al. | The [14C-N-methyl]-erythromycin breath test dosimetry complies with the French regulations for radiation safety. | 2003 | Fundam Clin Pharmacol | pmid:12803574 |
| Fountos A et al. | Duodenogastric reflux after biliary surgery: scintigraphic quantification and improvement with erythromycin. | 2003 | ANZ J Surg | pmid:12801337 |
| Tanikawa T et al. | Synthesis and antibacterial activity of a novel series of acylides: 3-O-(3-pyridyl)acetylerythromycin A derivatives. | 2003 | J. Med. Chem. | pmid:12801234 |
| Engel JN | Azithromycin-induced block of elementary body formation in Chlamydia trachomatis. | 1992 | Antimicrob. Agents Chemother. | pmid:1280057 |
| Ready D et al. | Oral bacteria resistant to mercury and to antibiotics are present in children with no previous exposure to amalgam restorative materials. | 2003 | FEMS Microbiol. Lett. | pmid:12799008 |
| Nakabayashi T et al. | Erythromycin induces pyloric relaxation accompanied by a contraction of the gastric body after pylorus-preserving gastrectomy. | 2003 | Surgery | pmid:12796733 |
| Rosenman MB et al. | Oral erythromycin prophylaxis vs watchful waiting in caring for newborns exposed to Chlamydia trachomatis. | 2003 | Arch Pediatr Adolesc Med | pmid:12796237 |
| Asakawa A et al. | EM574, a motilide, has an orexigenic activity with affinity for growth-hormone secretagogue receptor. | 2003 | J. Gastroenterol. Hepatol. | pmid:12795766 |
| Uchiyama N et al. | [The efficacy of switch therapy in community-acquired pneumonia in Japan]. | 2003 | Nihon Kokyuki Gakkai Zasshi | pmid:12795180 |
| Doherty WL and Winter B | Prokinetic agents in critical care. | 2003 | Crit Care | pmid:12793865 |