erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Bachmann K et al. | Steady-state pharmacokinetics of theophylline in COPD patients treated with dirithromycin. | 1993 | J Clin Pharmacol | pmid:8227485 |
Barcs I | Different kinetic of enzymatic inactivation of lincomycin and clindamycin in Staphylococcus aureus. | 1993 | J Chemother | pmid:8229148 |
Ichikawa Y et al. | Low-dose/long-term erythromycin for treatment of bronchiolitis obliterans organizing pneumonia (BOOP). | 1993 | Kurume Med J | pmid:8231065 |
Serino F et al. | Generation of oxygen free radicals during the metabolism of cyclosporine A: a cause-effect relationship with metabolism inhibition. | 1993 | Mol. Cell. Biochem. | pmid:8232241 |
Finland M et al. | Susceptibility of "enterobacteria" to penicillins, cephalosporins, lincomycins, erythromycin, and rifampin. | 1976 | J. Infect. Dis. | pmid:823280 |
Salmon P and Rademaker M | Erythema multiforme associated with an outbreak of Mycoplasma pneumoniae function. | 1993 | N. Z. Med. J. | pmid:8233176 |
Brummett RE | Ototoxic liability of erythromycin and analogues. | 1993 | Otolaryngol. Clin. North Am. | pmid:8233490 |
Bébéar C et al. | [Multicenter study of the in vitro sensitivity of genital mycoplasmas to antibiotics]. | 1993 | Pathol. Biol. | pmid:8233624 |
Rohner P et al. | Determination of MICs for staphylococci using the API ATB quinolone and API ATB macrolide systems. | 1993 | Pathol. Biol. | pmid:8233630 |
Bell TA et al. | Randomized trial of silver nitrate, erythromycin, and no eye prophylaxis for the prevention of conjunctivitis among newborns not at risk for gonococcal ophthalmitis. Eye Prophylaxis Study Group. | 1993 | Pediatrics | pmid:8233733 |
Romero R et al. | Antibiotic treatment of preterm labor with intact membranes: a multicenter, randomized, double-blinded, placebo-controlled trial. | 1993 | Am. J. Obstet. Gynecol. | pmid:8238130 |
Owen J et al. | Randomized trial of prophylactic antibiotic therapy after preterm amnion rupture. | 1993 | Am. J. Obstet. Gynecol. | pmid:8238160 |
Lonks JR and Medeiros AA | High rate of erythromycin and clarithromycin resistance among Streptococcus pneumoniae isolates from blood cultures from Providence, R.I. | 1993 | Antimicrob. Agents Chemother. | pmid:8239578 |
Klopman G et al. | Anti-Mycobacterium avium activity of quinolones: in vitro activities. | 1993 | Antimicrob. Agents Chemother. | pmid:8239587 |
Gohara Y et al. | In vitro and in vivo activities of Q-35, a new fluoroquinolone, against Mycoplasma pneumoniae. | 1993 | Antimicrob. Agents Chemother. | pmid:8239590 |
Menninger JR and Coleman RA | Lincosamide antibiotics stimulate dissociation of peptidyl-tRNA from ribosomes. | 1993 | Antimicrob. Agents Chemother. | pmid:8239627 |
Wiesner B et al. | Twice daily dosing of erythromycin acistrate in the treatment of acute bronchitis and pneumonia. | 1993 | Arzneimittelforschung | pmid:8240450 |
Bäckmann A et al. | Plasmid carriage and antibiotic susceptibility of Neisseria meningitidis strains isolated in Sweden 1981-1990. | 1993 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:8243484 |
Janecek M et al. | Determination of erythromycin A by liquid chromatography and electrochemical detection, with application to salmon tissue. | 1993 | J. Chromatogr. | pmid:8245164 |
Haglund LA et al. | Invasive pneumococcal disease in central Oklahoma: emergence of high-level penicillin resistance and multiple antibiotic resistance. Pneumococcus Study Group. | 1993 | J. Infect. Dis. | pmid:8245541 |
Poses RM et al. | Practice variation in the management of pharyngitis: the importance of variability in patients' clinical characteristics and in physicians' responses to them. | 1993 Oct-Dec | Med Decis Making | pmid:8246701 |
Török L et al. | [Bacillary angiomatosis]. | 1993 | Orv Hetil | pmid:8247515 |
Pajukanta R et al. | In vitro antimicrobial susceptibility of different serotypes of Actinobacillus actinomycetemcomitans. | 1993 | Scand J Dent Res | pmid:8248732 |
Goss JE et al. | Torsades de pointes associated with astemizole (Hismanal) therapy. | 1993 | Arch. Intern. Med. | pmid:8250668 |
Morgan AJ et al. | The effect of zinc in the form of erythromycin-zinc complex (Zineryt lotion) and zinc acetate on metallothionein expression and distribution in hamster skin. | 1993 | Br. J. Dermatol. | pmid:8251353 |
Hughes CM et al. | Cyclosporin A and erythromycin: a study of a drug interaction in the in situ perfused rat liver model. | 1993 | Biopharm Drug Dispos | pmid:8251616 |
Piérard GE and Piérard-Franchimont C | Effect of a topical erythromycin-zinc formulation on sebum delivery. Evaluation by combined photometric-multi-step samplings with Sebutape. | 1993 | Clin. Exp. Dermatol. | pmid:8252759 |
Peeters TL | Erythromycin and other macrolides as prokinetic agents. | 1993 | Gastroenterology | pmid:8253365 |
Dabernat H et al. | [Study of susceptibility of Haemophilus influenzae to antibiotics (other than beta-lactams) by using HTM gelose (Haemophilus test medium)]. | 1993 | Pathol. Biol. | pmid:8255611 |
Fremaux A et al. | [In vitro antibacterial activity of pristinamycin against penicillin resistant Streptococcus pneumoniae]. | 1993 | Pathol. Biol. | pmid:8255615 |
Fass RJ | Erythromycin, clarithromycin, and azithromycin: use of frequency distribution curves, scattergrams, and regression analyses to compare in vitro activities and describe cross-resistance. | 1993 | Antimicrob. Agents Chemother. | pmid:8257127 |
Thomas NH et al. | Mycoplasma pneumoniae infection and neurological disease. | 1993 | Arch. Dis. Child. | pmid:8257178 |
Herings RM et al. | Public health problems and the rapid estimation of the size of the population at risk. Torsades de pointes and the use of terfenadine and astemizole in The Netherlands. | 1993 | Pharm World Sci | pmid:8257958 |
Voros S et al. | Sensitivity test on Neisseria meningitidis strains to antimicrobial drugs. | 1975 | Ghana Med J | pmid:826042 |
Fiorucci S et al. | 5-hydroxytryptamine 3-receptor antagonist modulates gallbladder emptying and motilin release induced by erythromycin. | 1993 | Dig. Dis. Sci. | pmid:8261827 |
Belzer DL | Conjunctivitis treatment. | 1993 | Pediatr Ann | pmid:8265260 |
Mattila MJ et al. | Oral single doses of erythromycin and roxithromycin may increase the effects of midazolam on human performance. | 1993 | Pharmacol. Toxicol. | pmid:8265524 |
Shet MS et al. | Human cytochrome P450 3A4: enzymatic properties of a purified recombinant fusion protein containing NADPH-P450 reductase. | 1993 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8265621 |
van der Lely N et al. | [A child with Chlamydia trachomatis pneumonia]. | 1993 | Tijdschr Kindergeneeskd | pmid:8266317 |
Peeters TL | Agonist effect of erythromycin and its analogues on motilin receptors. A new family of prokinetics? Clinical interest. | 1993 May-Aug | Acta Gastroenterol. Belg. | pmid:8266766 |
Lamáury I et al. | Chlamydia psittaci as a cause of lethal bacterial endocarditis. | 1993 | Clin. Infect. Dis. | pmid:8268378 |
Kita E et al. | Proliferation of erythromycin-stimulated mouse peritoneal macrophages in the absence of exogenous growth factors. | 1993 Nov-Dec | Nat. Immun. | pmid:8268716 |
Palmer RH and Burnham D | Effects of erythromycin on alcohol absorption. | 1994 | J. Nucl. Med. | pmid:8271045 |
Ohno S et al. | [Clinical effects of low-dose and long-term erythromycin in diffuse panbronchiolitis with chronic respiratory failure]. | 1993 | Nihon Kyobu Shikkan Gakkai Zasshi | pmid:8271657 |
Carson J and Statham P | The inhibition by ionophores in vitro of an Enterococcus-like pathogen of rainbow trout, Oncorhynchus mykiss. | 1993 | Vet. Microbiol. | pmid:8273272 |
Tanner AC et al. | Adaptation of the Sensititre broth microdilution technique to antimicrobial susceptibility testing of Mycoplasma hyopneumoniae. | 1993 | Vet. Microbiol. | pmid:8273275 |
Kelley R et al. | Erythromycin. Still a good choice for strep throat. | 1993 | Clin Pediatr (Phila) | pmid:8275609 |
Kinirons MT et al. | Absence of correlations among three putative in vivo probes of human cytochrome P4503A activity in young healthy men. | 1993 | Clin. Pharmacol. Ther. | pmid:8275617 |
Nishi K et al. | [Effect of erythromycin on mucociliary transport and clinical symptoms in patients with sinobronchial syndrome]. | 1993 | Nihon Kyobu Shikkan Gakkai Zasshi | pmid:8277605 |
Devriese L | [Antibiotic sensitivity tests (author's transl)]. | 1976 | Tijdschr Diergeneeskd | pmid:827819 |
Mazieri NA and de Godoy CV | [Legionellosis associated with pneumopathies in São Paulo. Study of the etiologic confirmation by isolation and serology]. | 1993 Jan-Feb | Rev. Inst. Med. Trop. Sao Paulo | pmid:8278737 |
Cane DE | Polyketide biosynthesis: molecular recognition or genetic programming? | 1994 | Science | pmid:8278806 |
Marsden AF et al. | Stereospecific acyl transfers on the erythromycin-producing polyketide synthase. | 1994 | Science | pmid:8278811 |
Singh N et al. | Legionella infection in liver transplant recipients: implications for management. | 1993 | Transplantation | pmid:8279037 |
Lin HC et al. | Erythromycin accelerates solid emptying at the expense of gastric sieving. | 1994 | Dig. Dis. Sci. | pmid:8281846 |
Champion G et al. | Effects of oral erythromycin on esophageal pH and pressure profiles in patients with gastroesophageal reflux disease. | 1994 | Dig. Dis. Sci. | pmid:8281847 |
Inatomi N et al. | Comparison of the motor-stimulating action of EM523, an erythromycin derivative, and prostaglandin F2 alpha in conscious dogs. | 1993 | Jpn. J. Pharmacol. | pmid:8283832 |
Lees AW and Tyrrell WF | Severe cerebral disturbance in legionnaires' disease. | 1978 Dec 23-30 | Lancet | pmid:82840 |
Afghani B and Stutman HR | Bacterial arthritis caused by Corynebacterium diphtheriae. | 1993 | Pediatr. Infect. Dis. J. | pmid:8284128 |
Poland RL | Consultation with the specialist. Eye prophylaxis in the newborn infant. | 1993 | Pediatr Rev | pmid:8284277 |
Donowitz GR and Earnhardt KI | Azithromycin inhibition of intracellular Legionella micdadei. | 1993 | Antimicrob. Agents Chemother. | pmid:8285604 |
Teague AC and Parks SK | Bacillary angiomatosis in a patient with AIDS. | 1993 | Ann Pharmacother | pmid:8286814 |
Boiron M et al. | [Antro-pyloro-bulbar contractibility in diabetics studied by cineradiography. Effect of erythromycin]. | 1993 | Gastroenterol. Clin. Biol. | pmid:8288079 |
Malik A et al. | Congenital syphilis: a reappraisal. | 1993 | Indian Pediatr | pmid:8288353 |
Brunton WA et al. | Erythromycin-resistant campylobacters. | 1978 Dec 23-30 | Lancet | pmid:82888 |
Meheus A and Piot P | [Penicillinase-producing Neisseria gonorrhoeae]. | 1976 Nov-Dec | Arch Belg Med Soc | pmid:829480 |
Peeters TL et al. | The motilin antagonist ANQ-11125 blocks motilide-induced contractions in vitro in the rabbit. | 1994 | Biochem. Biophys. Res. Commun. | pmid:8297350 |
Erbas T et al. | Comparison of metoclopramide and erythromycin in the treatment of diabetic gastroparesis. | 1993 | Diabetes Care | pmid:8299441 |
Hsieh YJ and Kolattukudy PE | Inhibition of erythromycin synthesis by disruption of malonyl-coenzyme A decarboxylase gene eryM in Saccharopolyspora erythraea. | 1994 | J. Bacteriol. | pmid:8300527 |
Kirst HA | Semi-synthetic derivatives of erythromycin. | 1993 | Prog Med Chem | pmid:8303037 |
Gitler B et al. | Torsades de pointes induced by erythromycin. | 1994 | Chest | pmid:8306730 |
Hojo M et al. | Erythromycin does not directly affect neutrophil functions. | 1994 | Chest | pmid:8306756 |
Mills OH and Kligman AM | Treatment of acne vulgaris with topically applied erythromycin and tretinoin. | 1978 | Acta Derm. Venereol. | pmid:83088 |
Bausch LC | Newborn eye prophylaxis--where are we now? | 1993 | Nebr Med J | pmid:8309491 |
Pennathur A et al. | Erythromycin strengthens the defective lower esophageal sphincter in patients with gastroesophageal reflux disease. | 1994 | Am. J. Surg. | pmid:8311129 |
Jarvis BW and Hutchinson CR | Purification of a thymidine-diphospho-4-keto-6-deoxy-D-glucose epimerase from an erythromycin-producing strain of Saccharopolyspora erythraea. | 1994 | Arch. Biochem. Biophys. | pmid:8311450 |
László P et al. | [Toxic hearing damage caused by antibiotics]. | 1977 | Orv Hetil | pmid:831200 |
Kane MP et al. | Stability of erythromycin lactobionate in peritoneal dialysate solutions. | 1994 | Perit Dial Int | pmid:8312421 |
Sugiyama Y | Diffuse panbronchiolitis. | 1993 | Clin. Chest Med. | pmid:8313679 |
Chaussade S et al. | Motilin agonist erythromycin increases human lower esophageal sphincter pressure by stimulation of cholinergic nerves. | 1994 | Dig. Dis. Sci. | pmid:8313822 |
Narita N | [Recent progress on diagnosis and therapy of diffuse panbronchiolitis]. | 1993 | Nippon Naika Gakkai Zasshi | pmid:8315323 |
DeMarco MJ et al. | Epithelioid angiomatosis. | 1993 Jan-Feb | J Foot Ankle Surg | pmid:8318957 |
Stjernquist-Desatnik A et al. | Penetration of penicillin V to tonsillar surface fluid in healthy individuals and in patients with acute tonsillitis. | 1993 | J Laryngol Otol | pmid:8320515 |
Edelstein PH | Legionnaires' disease. | 1993 | Clin. Infect. Dis. | pmid:8329504 |
Winkler VW and Nyman MA | Collaborative study of assay method for erythromycin in pelleted feeds containing binding agents. | 1977 | J Assoc Off Anal Chem | pmid:833094 |
Mollet B et al. | Directed genomic integration, gene replacement, and integrative gene expression in Streptococcus thermophilus. | 1993 | J. Bacteriol. | pmid:8331064 |
Cook CS et al. | Involvement of cytochrome P-450IIIA in metabolism of potassium canrenoate to an epoxide: mechanism of inhibition of the epoxide formation by spironolactone and its sulfur-containing metabolite. | 1993 | J. Pharmacol. Exp. Ther. | pmid:8331551 |
Osborne ML and Wall M | Clinical problem-solving: too old for what? | 1993 | N. Engl. J. Med. | pmid:8332170 |
Marosvári I et al. | [Polyresistant Streptococcus pneumoniae causing cumulative diseases in infants and young children]. | 1993 | Orv Hetil | pmid:8332361 |
Lazarevski T et al. | Erythromycin series. V. Quantitative analysis of cladinose and methylcladinoside by densitometry of thin-layer chromatograms. | 1977 | J. Chromatogr. | pmid:833239 |
Biron CR | Erythromycin. | 1993 | RDH | pmid:8332759 |
Sakito O et al. | [Effect of erythromycin on neutrophil chemotactic activity from human monocytes]. | 1993 | Kansenshogaku Zasshi | pmid:8336016 |
Clarke CR et al. | Distribution of intramuscularly administered erythromycin into subcutaneous tissue chambers before and after inoculation with Pasteurella haemolytica. | 1993 | Res. Vet. Sci. | pmid:8337485 |
Xia AF | [Effect of oculentum erythromycin in the prevention of inflammatory conjunctivitis of neonates]. | 1993 | Zhonghua Hu Li Za Zhi | pmid:8339361 |
Bhatia V and Broor SL | Erythromycin and the gallbladder. | 1993 | Indian J Gastroenterol | pmid:8340147 |
Parish LC | Clarithromycin in the treatment of skin and skin structure infections: two multicenter clinical studies. Clarithromycin Study Group. | 1993 | Int. J. Dermatol. | pmid:8340194 |
Pennathur A et al. | Erythromycin, motilin, and the esophagus. | 1993 | Surgery | pmid:8342132 |
Genetello C et al. | Ti plasmids of Agrobacterium as conjugative plasmids. | 1977 | Nature | pmid:834309 |
Guggenbichler JP and Berger H | [Mycoplasma pneumonias in childhood (author's transl)]. | 1977 | Padiatr Padol | pmid:834454 |
Heininger U et al. | Clinical and laboratory diagnosis of pertussis in the regions of a large vaccine efficacy trial in Germany. | 1993 | Pediatr. Infect. Dis. J. | pmid:8345982 |