erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Brown GR | Erythromycin-induced hypotension. | 1995 | Ann Pharmacother | pmid:8547744 |
Stein CM et al. | Comparison of the dapsone recovery ratio and the erythromycin breath test as in vivo probes of CYP3A activity in patients with rheumatoid arthritis receiving cyclosporine. | 1996 | Clin. Pharmacol. Ther. | pmid:8549033 |
Bojar RA et al. | Direct analysis of resistance in the cutaneous microflora during treatment of acne vulgaris with topical 1% nadifloxacin and 2% erythromycin. | 1995 | Drugs | pmid:8549289 |
Morrissey I and Smith JT | Activity of new 4-quinolones in combination with erythromycin or tetracycline against S. pneumoniae. | 1995 | Drugs | pmid:8549311 |
Saito A and Gaja M | In vitro and in vivo activities of sparfloxacin in Legionella infections. | 1995 | Drugs | pmid:8549320 |
Fujimura M et al. | Additive effect of continuous low dose ofloxacin on erythromycin therapy for sinobronchial syndrome. | 1995 | Drugs | pmid:8549380 |
Kawahara S et al. | Inhibitory effect of ofloxacin on acute exacerbations of chronic respiratory tract infections in comparison with erythromycin. | 1995 | Drugs | pmid:8549382 |
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Mitsuyama T et al. | Inhibition by erythromycin of superoxide anion production by human polymorphonuclear leukocytes through the action of cyclic AMP-dependent protein kinase. | 1995 | Respiration | pmid:8560094 |
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Martins C et al. | Allergic contact dermatitis from erythromycin. | 1995 | Contact Derm. | pmid:8565504 |
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Christie CD et al. | Containment of pertussis in the regional pediatric hospital during the Greater Cincinnati epidemic of 1993. | 1995 | Infect Control Hosp Epidemiol | pmid:8568199 |
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Ishiura Y et al. | Additive effect of continuous low-dose ofloxacin on erythromycin therapy for sinobronchial syndrome. | 1995 | Respir Med | pmid:8570882 |
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Goswami BB et al. | Physico-chemical properties and biological activities of erythromycin nalidixate. | 1995 | Arzneimittelforschung | pmid:8573228 |
Lynch HC and Bushell ME | The physiology of erythromycin biosynthesis in cyclic fed batch culture. | 1995 | Microbiology (Reading, Engl.) | pmid:8574403 |
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Khair OA et al. | Effect of erythromycin on Haemophilus influenzae endotoxin-induced release of IL-6, IL-8 and sICAM-1 by cultured human bronchial epithelial cells. | 1995 | Eur. Respir. J. | pmid:8575568 |
Masclee AA et al. | Effect of antrectomy and truncal vagotomy on erythromycin induced pancreatic polypeptide secretion. | 1995 | Regul. Pept. | pmid:8577928 |
Slomiany BL et al. | Sucralfate affects the susceptibility of Helicobacter pylori to antimicrobial agents. | 1995 | Scand. J. Gastroenterol. Suppl. | pmid:8578215 |
Minocha A et al. | Erythromycin shortens orocaecal transit time in diabetic male subjects: a double-blind placebo-controlled study. | 1995 | Aliment. Pharmacol. Ther. | pmid:8580273 |
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Burt M et al. | Erythromycin stimulates gastric emptying after esophagectomy with gastric replacement: a randomized clinical trial. | 1996 | J. Thorac. Cardiovasc. Surg. | pmid:8601981 |
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