erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hypersplenism D006971 3 associated lipids
Splenic Infarction D013159 1 associated lipids
Mastoiditis D008417 2 associated lipids
Onychomycosis D014009 2 associated lipids
Hematemesis D006396 1 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Duodenogastric Reflux D004383 2 associated lipids
Trisomy D014314 6 associated lipids
Epidural Abscess D020802 1 associated lipids
Trench Fever D014205 1 associated lipids
Herpes Genitalis D006558 2 associated lipids
Compartment Syndromes D003161 1 associated lipids
Wounds, Gunshot D014948 2 associated lipids
Pericoronitis D010497 2 associated lipids
Postoperative Nausea and Vomiting D020250 1 associated lipids
Eye Infections, Parasitic D015822 2 associated lipids
Myiasis D009198 1 associated lipids
Digestive System Abnormalities D004065 1 associated lipids
Choroiditis D002833 1 associated lipids
Pelvic Infection D034161 1 associated lipids
Seroma D049291 2 associated lipids
Choanal Atresia D002754 1 associated lipids
Limb Deformities, Congenital D017880 4 associated lipids
Microphthalmos D008850 1 associated lipids
Chalazion D017043 1 associated lipids
Acalculous Cholecystitis D042101 3 associated lipids
Pneumonia, Ventilator-Associated D053717 1 associated lipids
Tooth Fractures D014082 2 associated lipids
Sebaceous Gland Diseases D012625 1 associated lipids
Adrenocortical Carcinoma D018268 4 associated lipids
Granuloma, Respiratory Tract D015769 1 associated lipids
Staphylococcal Scalded Skin Syndrome D013206 1 associated lipids
Stomatognathic Diseases D009057 1 associated lipids
Moraxellaceae Infections D045828 3 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Fecal Incontinence D005242 1 associated lipids
Atrioventricular Block D054537 1 associated lipids
Abdominal Abscess D018784 2 associated lipids
Vagus Nerve Injuries D061223 1 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Hoarseness D006685 2 associated lipids
Occupational Injuries D060051 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Authors Title Published Journal PubMed Link
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van Hoogdalem EJ et al. Evaluation of the effect of zinc acetate on the stratum corneum penetration kinetics of erythromycin in healthy male volunteers. 1996 Skin Pharmacol. pmid:8722604
Champney WS and Burdine R 50S ribosomal subunit synthesis and translation are equivalent targets for erythromycin inhibition in Staphylococcus aureus. 1996 Antimicrob. Agents Chemother. pmid:8723490
Fujii T et al. Inhibitory effect of erythromycin on interleukin 8 production by 1 alpha,25-dihydroxyvitamin D3-stimulated THP-1 cells. 1996 Antimicrob. Agents Chemother. pmid:8726037
Brouqui P et al. Eucaryotic cells protect Borrelia burgdorferi from the action of penicillin and ceftriaxone but not from the action of doxycycline and erythromycin. 1996 Antimicrob. Agents Chemother. pmid:8726038
Lopes Cardoso FL et al. Rhodococcus equi mastoiditis in a patient with AIDS. 1996 Clin. Infect. Dis. pmid:8729214
Moore JE et al. Erythromycin-resistant thermophilic Campylobacter species isolated from pigs. 1996 Vet. Rec. pmid:8730692
Box SA and Lee MR A systemic reaction following exposure to a pyrethroid insecticide. 1996 Hum Exp Toxicol pmid:8735461
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