erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| DiBaise JK et al. | Effects of low doses of erythromycin on the 13C Spirulina platensis gastric emptying breath test and electrogastrogram: a controlled study in healthy volunteers. | 2001 | Am. J. Gastroenterol. | pmid:11467630 |
| Hamilton HL et al. | Insertion-duplication mutagenesis of neisseria: use in characterization of DNA transfer genes in the gonococcal genetic island. | 2001 | J. Bacteriol. | pmid:11466274 |
| Hartog BJ et al. | Systemic bioavailability of erythromycin in cattle when applied by footbath. | 2001 | Vet. Rec. | pmid:11465266 |
| Johnson AP et al. | Activity of the ketolide telithromycin (HMR-3647) against erythromycin-susceptible and -resistant pneumococci isolated in the UK. | 2001 | Int. J. Antimicrob. Agents | pmid:11463530 |
| Rondini G et al. | Bacteriological and clinical efficacy of various antibiotics used in the treatment of streptococcal pharyngitis in Italy. An epidemiological study. | 2001 | Int. J. Antimicrob. Agents | pmid:11463521 |
| Barnwell PA et al. | A clinical approach to the choice of antimicrobial agents, case number 10: atypical pneumonia. | 1979 | J Ky Med Assoc | pmid:114597 |
| RodrÃguez D and Danés I | [New antibiotic therapies for acute pharyngotonsillitis]. | 2001 | Med Clin (Barc) | pmid:11459582 |
| Strazisar SA and Wolczanski PT | Insertion of H2C=CHX (X = F, Cl, Br, O(i)Pr) into (tBu3SiO)3TaH2 and beta-X-Elimination from (tBu3SiO)3HTaCH2CH2X (X = OR): relevance to Ziegler-Natta copolymerizations. | 2001 | J. Am. Chem. Soc. | pmid:11457282 |
| Al-Abdulla NA and Kim MC | Aerosol keratopathy: a revised MacLean classification. | 2001 Apr-Jun | Eur J Ophthalmol | pmid:11456024 |
| Del Rosso JQ | Systemic therapy for rosacea: focus on oral antibiotic therapy and safety. | 2000 | Cutis | pmid:11455753 |
| Cha S et al. | The emergence of erythromycin-resistant Streptococcus pyogenes in Seoul, Korea. | 2001 | J. Infect. Chemother. | pmid:11455497 |
| Ose L | [Encephalitis associated with mycoplasma pneumoniae infection in children]. | 1975 | Tidsskr. Nor. Laegeforen. | pmid:1145545 |
| Piessevaux H et al. | Perception of changes in wall tension of the proximal stomach in humans. | 2001 | Gut | pmid:11454795 |
| Facinelli B et al. | Association between erythromycin resistance and ability to enter human respiratory cells in group A streptococci. | 2001 | Lancet | pmid:11454374 |
| Yamada G et al. | Centrilobular nodules correlate with air trapping in diffuse panbronchiolitis during erythromycin therapy. | 2001 | Chest | pmid:11451838 |
| De Mouy D et al. | Antibiotic susceptibility and mechanisms of erythromycin resistance in clinical isolates of Streptococcus agalactiae: French multicenter study. | 2001 | Antimicrob. Agents Chemother. | pmid:11451709 |
| Jacobs JA et al. | Prevalence of macrolide resistance genes in clinical isolates of the Streptococcus anginosus ("S. milleri") group. | 2001 | Antimicrob. Agents Chemother. | pmid:11451701 |
| Goldstein EJ et al. | In vitro activities of ABT-773, a new ketolide, against aerobic and anaerobic pathogens isolated from antral sinus puncture specimens from patients with sinusitis. | 2001 | Antimicrob. Agents Chemother. | pmid:11451698 |
| Clarebout G et al. | Macrolide resistance gene mreA of Streptococcus agalactiae encodes a flavokinase. | 2001 | Antimicrob. Agents Chemother. | pmid:11451686 |
| Gregory D et al. | Activity of penicillin, erythromycin, and cephalosporins against isolates of Corynebacterium diphtheriae from cutaneous lesions. | 1979 | J. Antimicrob. Chemother. | pmid:114513 |
| Lo Bue AM et al. | Antibacterial activity and post-antibiotic effect of flurithromycin compared with other macrolides and penicillins against periodontal pathogens. | 2001 | J Chemother | pmid:11450882 |
| Dubois J and St -Pierre C | In vitro activity of ABT-773 versus macrolides and quinolones against resistant respiratory tract pathogens. | 2001 May-Jun | Diagn. Microbiol. Infect. Dis. | pmid:11448561 |
| Garzotti M et al. | Coupling of a supercritical fluid chromatography system to a hybrid (Q-TOF 2) mass spectrometer: on-line accurate mass measurements. | 2001 | Rapid Commun. Mass Spectrom. | pmid:11445901 |
| Corneau N et al. | A coelectroporation method for the isolation of cryptic plasmids from Lactococcus lactis. | 2001 | Lett. Appl. Microbiol. | pmid:11442806 |
| Brandt CM et al. | Macrolide resistance in Streptococcus pyogenes isolates from throat infections in the region of Aachen, Germany. | 2001 | Microb. Drug Resist. | pmid:11442342 |
| Idesaki M et al. | [Effects of various erythromycin derivatives on activation of transcription factors in airway epithelial cells]. | 2001 | Jpn J Antibiot | pmid:11439910 |
| Tamaoki A et al. | [Effects and action mechanisms of macrolides on IgG- immune complex lung injury models]. | 2001 | Jpn J Antibiot | pmid:11439907 |
| Taguchi Y | [Guidelines for small dosage macrolide therapy of patients with diffuse panbronchiolitis and reports of adverse effects]. | 2001 | Jpn J Antibiot | pmid:11439900 |
| Dobashi Y et al. | [Effects of macrolides on neutrophil apoptosis, IL-8 production, and neutrophil clearance mechanism]. | 2001 | Jpn J Antibiot | pmid:11439897 |
| Inesawa H et al. | [Effects of macrolide antibiotics on immune cells derived from human peripheral blood]. | 2001 | Jpn J Antibiot | pmid:11439894 |
| Hashimoto N et al. | [Effects of erythromycin on matrix metalloproteinase-9(MMP-9)and cell migration]. | 2001 | Jpn J Antibiot | pmid:11439893 |
| Enomoto F et al. | [Effects of macrolides on cultured rat vascular cells]. | 2001 | Jpn J Antibiot | pmid:11439891 |
| Takahashi T et al. | [Effects of erythromycin on the Pseudomonas-induced rabbit diffuse panbronchiolitis model--the improvements in granuloma-like lesions with increasing production of MCP-1]. | 2001 | Jpn J Antibiot | pmid:11439890 |
| Azuma A et al. | [Case of the bare lymphocyte syndrome successfully treated with long-term small dosage administration of erythromycin]. | 2001 | Jpn J Antibiot | pmid:11439887 |
| Matsunaga Y et al. | [Therapeutic effects of macrolides on patients with palmoplantar pustulosis]. | 2001 | Jpn J Antibiot | pmid:11439885 |
| Komiya N and Tamaoki K | [Therapeutic effects of macrolides on patients with psoriasis vulgaris, pigmentary prurigo, or eosinophilic pustule folliculitis]. | 2001 | Jpn J Antibiot | pmid:11439883 |
| Honba K et al. | [Erythromycin uptake pathways in Shigella]. | 2001 | Jpn J Antibiot | pmid:11436833 |
| Tomich PK et al. | A transposon (Tn917) in Streptococcus faecalis that exhibits enhanced transposition during induction of drug resistance. | 1979 | Cold Spring Harb. Symp. Quant. Biol. | pmid:114353 |
| McGee L et al. | Nomenclature of major antimicrobial-resistant clones of Streptococcus pneumoniae defined by the pneumococcal molecular epidemiology network. | 2001 | J. Clin. Microbiol. | pmid:11427569 |
| Gutschow CA et al. | Bile exposure of the denervated stomach as an esophageal substitute. | 2001 | Ann. Thorac. Surg. | pmid:11426748 |
| Courbot A et al. | [Sinobronchial syndrome]. | 2001 | Rev Mal Respir | pmid:11424716 |
| Canzano JC and Lim JI | Pars plana vitrectomy for epiretinal membrane secondary to cat scratch neuroretinitis. | 2001 | Retina (Philadelphia, Pa.) | pmid:11421023 |
| Gregory ST et al. | Spontaneous erythromycin resistance mutation in a 23S rRNA gene, rrlA, of the extreme thermophile Thermus thermophilus IB-21. | 2001 | J. Bacteriol. | pmid:11418580 |
| Grub S et al. | The interaction of saquinavir (soft gelatin capsule) with ketoconazole, erythromycin and rifampicin: comparison of the effect in healthy volunteers and in HIV-infected patients. | 2001 | Eur. J. Clin. Pharmacol. | pmid:11417442 |
| Losa M et al. | CI (critical incidents) vs. CI (corporate identity). | 2001 | Swiss Med Wkly | pmid:11416892 |
| Chrysos E et al. | Erythromycin enhances oesophageal motility in patients with gastro-oesophageal reflux. | 2001 | ANZ J Surg | pmid:11413601 |
| Yin Y et al. | Erythromycin biosynthesis. The 4-pro-S hydride of NADPH is utilized for ketoreduction by both module 5 and module 6 of the 6-deoxyerythronolide B synthase. | 2001 | Bioorg. Med. Chem. Lett. | pmid:11412964 |
| Miller SD | Madura foot: treatment of Nocardia nova infection with antibiotics alone. | 2001 | Am J. Orthop. | pmid:11411876 |
| Nilius AM et al. | Comparative in vitro activity of ABT-773, a novel antibacterial ketolide. | 2001 | Antimicrob. Agents Chemother. | pmid:11408246 |
| Hoban DJ et al. | Macrolide-resistant Streptococcus pneumoniae in Canada during 1998-1999: prevalence of mef(A) and erm(B) and susceptibilities to ketolides. | 2001 | Antimicrob. Agents Chemother. | pmid:11408241 |
| Kawamura-Sato K et al. | Postantibiotic suppression effect of macrolides on the expression of flagellin in Pseudomonas aeruginosa and Proteus mirabilis. | 2001 | J. Infect. Chemother. | pmid:11406758 |
| Ng E and Shah V | Erythromycin for feeding intolerance in preterm infants. | 2001 | Cochrane Database Syst Rev | pmid:11406010 |
| Takahashi T et al. | Erythromycin attenuates an experimental model of chronic bronchiolitis via augmenting monocyte chemoattractant protein-1. | 2001 | Eur. Respir. J. | pmid:11405512 |
| PÃriz S et al. | Comparison of erythromycin and oxytetracycline for the treatment of ovine footrot. | 2001 | Acta Vet. Hung. | pmid:11402641 |
| Butrous G and Siegel RL | Sildenafil (Viagra) prolongs cardiac repolarization by blocking the rapid component of the delayed rectifier potassium current. | 2001 | Circulation | pmid:11401951 |
| Usary J and Champney WS | Erythromycin inhibition of 50S ribosomal subunit formation in Escherichia coli cells. | 2001 | Mol. Microbiol. | pmid:11401702 |
| Lim J and Yun H | Postantibiotic effects and postantibiotic sub-MIC effects of erythromycin, roxithromycin, tilmicosin, and tylosin on Pasteurella multocida. | 2001 | Int. J. Antimicrob. Agents | pmid:11397617 |
| Rospide MF et al. | Comparative antimicrobial activity of ABT-773, a novel ketolide, tested against drug-resistant Gram-positive cocci and Haemophilus influenzae. | 2001 | Int. J. Antimicrob. Agents | pmid:11397614 |
| Svejda J and Richter J | [The hepatotoxic action of erythromycin (author's transl)]. | 1975 | Cas. Lek. Cesk. | pmid:1139592 |
| Schuster-Bruce M | Gastric emptying in the critically ill. | 2001 | Crit. Care Med. | pmid:11395631 |
| Sudden death in a traveler following halofantrine administration--Togo, 2000. | 2001 | MMWR Morb. Mortal. Wkly. Rep. | pmid:11393488 | |
| Fox KK et al. | Gonorrhea in the HIV era: a reversal in trends among men who have sex with men. | 2001 | Am J Public Health | pmid:11392941 |
| Kim C et al. | The role of serine-246 in cytochrome P450eryF-catalyzed hydroxylation of 6-deoxyerythronolide B. | 2001 | Biosci. Biotechnol. Biochem. | pmid:11388449 |
| Claesson K et al. | Sirolimus and erythromycin interaction: two cases. | 2001 | Transplant. Proc. | pmid:11377477 |
| Whitehead TR and Cotta MA | Sequence analyses of a broad host-range plasmid containing ermT from a tylosin-resistant Lactobacillus sp. Isolated from swine feces. | 2001 | Curr. Microbiol. | pmid:11375658 |
| Fardis M et al. | Synthesis of 14,15-dehydroerythromycin A ketolides: effects of the 13-substituent on erythromycin tautomerism. | 2001 | J. Antibiot. | pmid:11372784 |
| Sambol SP et al. | Infection of hamsters with epidemiologically important strains of Clostridium difficile. | 2001 | J. Infect. Dis. | pmid:11372028 |
| Takedomi S et al. | In-vivo kinetics of the interaction between midazolam and erythromycin in rats, taking account of metabolic intermediate complex formation. | 2001 | J. Pharm. Pharmacol. | pmid:11370704 |
| Germaniskis L and Singer EJ | HIV and peripheral neuropathy. | 1995 | J Int Assoc Physicians AIDS Care | pmid:11362726 |
| Ray RS et al. | Evaluation of UV-induced superoxide radical generation potential of some common antibiotics. | 2001 | Drug Chem Toxicol | pmid:11360435 |
| Rowe CJ et al. | Engineering a polyketide with a longer chain by insertion of an extra module into the erythromycin-producing polyketide synthase. | 2001 | Chem. Biol. | pmid:11358694 |
| Dujovne CA | Liver cell culture toxicity and surfactant potency of erythromycin derivatives. | 1975 | Toxicol. Appl. Pharmacol. | pmid:1135866 |
| Marti GarcÃa JL et al. | [Rheumatic pneumonitis]. | 1975 | Rev Clin Esp | pmid:1135467 |
| Bonnefoy A et al. | In vivo efficacy of the new ketolide telithromycin (HMR 3647) in murine infection models. | 2001 | Antimicrob. Agents Chemother. | pmid:11353612 |
| Chitturi S and Farrell GC | Drug-induced cholestasis. | 2001 | Semin. Gastrointest. Dis. | pmid:11352118 |
| Akritopoulou-Zanze I and Sowin TJ | Solid-phase synthesis of macrolide analogues. | 2001 May-Jun | J Comb Chem | pmid:11350254 |
| Dobbin CJ et al. | The efficacy of an antibiotic protocol for community-acquired pneumonia. | 2001 | Med. J. Aust. | pmid:11346105 |
| Corcoran JW | S-adenosylmethionine:erythromycin C O-methyltransferase. | 1975 | Meth. Enzymol. | pmid:1134368 |
| Wang M et al. | Prevalence and phenotypes of erythromycin-resistant Streptococcus pneumoniae in Shanghai, China. | 2001 | Diagn. Microbiol. Infect. Dis. | pmid:11337187 |
| Samra Z et al. | In vitro susceptibility of recent clinical isolates of Chlamydia trachomatis to macrolides and tetracyclines. | 2001 | Diagn. Microbiol. Infect. Dis. | pmid:11337185 |
| Rawlings BJ | Type I polyketide biosynthesis in bacteria (Part A--erythromycin biosynthesis). | 2001 | Nat Prod Rep | pmid:11336289 |
| Gintant GA et al. | The canine Purkinje fiber: an in vitro model system for acquired long QT syndrome and drug-induced arrhythmogenesis. | 2001 | J. Cardiovasc. Pharmacol. | pmid:11336111 |
| Hondeghem LM et al. | Phase 2 prolongation, in the absence of instability and triangulation, antagonizes class III proarrhythmia. | 2001 | Cardiovasc. Res. | pmid:11334838 |
| Takiguchi Y et al. | Fulminant Mycoplasma pneumoniae pneumonia. | 2001 | Intern. Med. | pmid:11334397 |
| Gharpure V et al. | Efficacy of erythromycin for postpyloric placement of feeding tubes in critically ill children: a randomized, double-blind, placebo controlled study. | 2001 May-Jun | JPEN J Parenter Enteral Nutr | pmid:11334066 |
| Ibarrola M et al. | [Disseminated disease by Mycobacterium kansasii resistant to isoniazid and rifampin in patients] with AIDS]. | 2001 | Enferm. Infecc. Microbiol. Clin. | pmid:11333577 |
| Hattori A et al. | [A case of Folliculitis barbae Candidomycetica]. | 2001 | Nihon Ishinkin Gakkai Zasshi | pmid:11331469 |
| Zarantonelli L et al. | Decreased susceptibility to azithromycin and erythromycin mediated by a novel mtr(R) promoter mutation in Neisseria gonorrhoeae. | 2001 | J. Antimicrob. Chemother. | pmid:11328778 |
| Martin SJ et al. | The activity of 14-hydroxy clarithromycin, alone and in combination with clarithromycin, against penicillin- and erythromycin-resistant Streptococcus pneumoniae. | 2001 | J. Antimicrob. Chemother. | pmid:11328768 |
| Curry JI et al. | Review article: erythromycin as a prokinetic agent in infants and children. | 2001 | Aliment. Pharmacol. Ther. | pmid:11328252 |
| Tsuji SY et al. | Selective protein-protein interactions direct channeling of intermediates between polyketide synthase modules. | 2001 | Biochemistry | pmid:11327852 |
| Rivory LP et al. | The erythromycin breath test for the prediction of drug clearance. | 2001 | Clin Pharmacokinet | pmid:11327195 |
| From the Centers for Disease Control and Prevention. Sudden death in a traveler following halofantrine administration--Togo, 2000. | 2001 | JAMA | pmid:11324646 | |
| Weeda LW | Erythromycin and amoxicillin? | 2001 | J Tenn Dent Assoc | pmid:11324196 |
| Kim HS et al. | Double-edged sword of chemosensitizer: increase of multidrug resistance protein (MRP) in leukemic cells by an MRP inhibitor probenecid. | 2001 | Biochem. Biophys. Res. Commun. | pmid:11322768 |
| Lanbeck P and Paulsen O | Short-term effects of four antibiotics on DNA synthesis in endothelial cells. | 2001 | Pharmacol. Toxicol. | pmid:11322179 |
| Rouzica M and Filipová K | [On the article of J. Buchanec and V. Kdrajnák: Lesions of the liver during therapy with erythromycin in 3 children]. | 1975 | Cesk Pediatr | pmid:1132045 |
| Ng PC et al. | Randomised controlled study of oral erythromycin for treatment of gastrointestinal dysmotility in preterm infants. | 2001 | Arch. Dis. Child. Fetal Neonatal Ed. | pmid:11320044 |
| Fogarty CM et al. | Effectiveness of levofloxacin for adult community-acquired pneumonia caused by macrolide-resistant Streptococcus pneumoniae: integrated results from four open-label, multicenter, phase III clinical trials. | 2001 | Clin Ther | pmid:11318077 |
| Ripa S et al. | SmaI macrorestriction analysis of Italian isolates of erythromycin-resistant Streptococcus pyogenes and correlations with macrolide-resistance phenotypes. | 2001 | Microb. Drug Resist. | pmid:11310805 |