erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Hypersplenism D006971 3 associated lipids
Splenic Infarction D013159 1 associated lipids
Mastoiditis D008417 2 associated lipids
Onychomycosis D014009 2 associated lipids
Hematemesis D006396 1 associated lipids
Pityriasis Rosea D017515 3 associated lipids
Duodenogastric Reflux D004383 2 associated lipids
Trisomy D014314 6 associated lipids
Epidural Abscess D020802 1 associated lipids
Trench Fever D014205 1 associated lipids
Herpes Genitalis D006558 2 associated lipids
Compartment Syndromes D003161 1 associated lipids
Wounds, Gunshot D014948 2 associated lipids
Pericoronitis D010497 2 associated lipids
Postoperative Nausea and Vomiting D020250 1 associated lipids
Eye Infections, Parasitic D015822 2 associated lipids
Myiasis D009198 1 associated lipids
Digestive System Abnormalities D004065 1 associated lipids
Choroiditis D002833 1 associated lipids
Pelvic Infection D034161 1 associated lipids
Seroma D049291 2 associated lipids
Choanal Atresia D002754 1 associated lipids
Limb Deformities, Congenital D017880 4 associated lipids
Microphthalmos D008850 1 associated lipids
Chalazion D017043 1 associated lipids
Acalculous Cholecystitis D042101 3 associated lipids
Pneumonia, Ventilator-Associated D053717 1 associated lipids
Tooth Fractures D014082 2 associated lipids
Sebaceous Gland Diseases D012625 1 associated lipids
Adrenocortical Carcinoma D018268 4 associated lipids
Granuloma, Respiratory Tract D015769 1 associated lipids
Staphylococcal Scalded Skin Syndrome D013206 1 associated lipids
Stomatognathic Diseases D009057 1 associated lipids
Moraxellaceae Infections D045828 3 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Fecal Incontinence D005242 1 associated lipids
Atrioventricular Block D054537 1 associated lipids
Abdominal Abscess D018784 2 associated lipids
Vagus Nerve Injuries D061223 1 associated lipids
Pyloric Stenosis, Hypertrophic D046248 2 associated lipids
Hoarseness D006685 2 associated lipids
Occupational Injuries D060051 1 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Henkes M et al. Therapeutic options for chronic myeloid leukemia: focus on imatinib (Glivec, Gleevectrade mark). 2008 Ther Clin Risk Manag pmid:18728706
Miles MV and Tennison MB Erythromycin effects on multiple-dose carbamazepine kinetics. 1989 Ther Drug Monit pmid:2911854
Hedrick R et al. Carbamazepine--erythromycin interaction leading to carbamazepine toxicity in four epileptic children. 1983 Ther Drug Monit pmid:6659014
Wadhwa NK et al. Interaction between erythromycin and cyclosporine in a kidney and pancreas allograft recipient. 1987 Ther Drug Monit pmid:3554626
Watkins PB Erythromycin breath test and clinical transplantation. 1996 Ther Drug Monit pmid:8857552
Buiter HJ et al. Erythromycin precipitation in vena femoralis: investigation of crystals found in postmortem material of an intensive care unit patient. 2008 Ther Drug Monit pmid:18223476
Baciewicz AM Carbamazepine drug interactions. 1986 Ther Drug Monit pmid:3092407
Wadhwa NK et al. Cyclosporine drug interactions: a review. 1987 Ther Drug Monit pmid:3321582
Birkett DJ et al. Single oral dose pharmacokinetics of erythromycin and roxithromycin and the effects of chronic dosing. 1990 Ther Drug Monit pmid:2305423
de Wildt SN et al. 13C-erythromycin breath test as a noninvasive measure of CYP3A activity in newborn infants: a pilot study. 2007 Ther Drug Monit pmid:17417078
Padhi ID et al. Interaction between tacrolimus and erythromycin. 1997 Ther Drug Monit pmid:9029762
Luurila H et al. Lack of interaction of erythromycin with temazepam. 1994 Ther Drug Monit pmid:7878692
FIEGEL G [The place of erythromycin among the antibiotics]. 1957 Ther Ggw pmid:13422363
ILKER HG [Not Available]. 1957 Ther Ggw pmid:13422370
Petzoldt D [Current diagnosis and therapy of acquired syphilis]. 1973 Ther Ggw pmid:4708581
Münnich D et al. Observations on micro-encapsulated erythromycin (Eryc capsule) in the treatment of various infections of adults. 1988 Ther Hung pmid:3249998
Ferencz A et al. Use of Eryc capsule in adult patients. 1989 Ther Hung pmid:2686082
RUBANYI P and KOS R ACTUAL PROBLEMS OF ANTIBIOTIC TREATMENT IN SURGICAL PRACTICE. 1963 Ther Hung pmid:14133128
Adám A and Kuberka Z Use of a new erythromycin product--eryc--in the treatment of the lower respiratory tract infections. 1990 Ther Hung pmid:2094053
Hoppe JE [Pertussis: current aspects of diagnosis, therapy and prevention]. 1998 Ther Umsch pmid:9492614
Meyer JC and Eichmann A [Serodiagnosis and therapy of syphilis]. 1985 Ther Umsch pmid:3911474
Korting HC [Urethritis in the male, diagnosis and therapy]. 1985 Ther Umsch pmid:2935962
Lagier G et al. [A minor case of ergotism appearing to be connected with a potentialisation of ergotamine tartrate by erythromycine ethyl-succinate (author's transl)]. 1979 Jul-Aug Therapie pmid:531783
Bergogne-Berezin E et al. [Experimental study of the possible influence of a fluidifying agent (bromhexine) on the penetration of erythromycine into bronchial secretions (author's transl)]. 1979 Nov-Dec Therapie pmid:547444
Baldit C et al. [Influence of a new macrolide, dirithromycine, on the clearance of antipyrine]. 1987 May-Jun Therapie pmid:3660320
Bavoux F [Torsades de pointes and anti-infective agents]. 1992 Sep-Oct Therapie pmid:1299973
VIALLIER J et al. [Study of the blood levels obtained with 2 new esters of erythromycin: propionyl erythromycin and propionyl erythromycin lauryl sulfate]. 1961 Nov-Dec Therapie pmid:13925737
Kanfer A et al. [Erythromycin ototoxicity in patients with renal insufficiency (author's transl)]. 1980 May-Jun Therapie pmid:7423428
Hugues FC et al. [Cochlear toxicity of erythromycin in elderly patients]. 1984 Sep-Oct Therapie pmid:6506017
TREFOUEL J et al. [Not Available]. 1959 Therapie pmid:13647435
Moutard I et al. In vitro effects of spiramycin and dirithromycin on IL1 beta production by human LPS-stimulated mononuclear cells. 1999 Sep-Oct Therapie pmid:10667098
GROTHUESMANN HG [DEVELOPMENT OF RESISTANCE OF PATHOGENIC URINARY BACTERIA TO THE MOST COMMON ANTIBIOTICS]. 1964 Therapiewoche pmid:14143496
Yousaf N et al. Long-term low-dose erythromycin in patients with unexplained chronic cough: a double-blind placebo controlled trial. 2010 Thorax pmid:20965928
Azuma A et al. Preventive effect of erythromycin on experimental bleomycin-induced acute lung injury in rats. 1998 Thorax pmid:9659353
Waterworth PM et al. A critical investigation into the antibiotic sterilization of heart valve homografts. 1974 Thorax pmid:4368321
Dorrell L et al. Intravenous azithromycin as salvage therapy in a patient with Legionnaire's disease. 1994 Thorax pmid:8016806
White RJ Why use erythromycin? 1994 Thorax pmid:7974308
Oaklay CM Prevention of infective endocarditis. 1979 Thorax pmid:542909
Brennan S et al. Directed neutrophil migration to IL-8 is increased in cystic fibrosis: a study of the effect of erythromycin. 2001 Thorax pmid:11120907
Ellis ME and Dunbar EM In vivo response of acute Q fever to erythromycin. 1982 Thorax pmid:7164010
Domingo C et al. Radiographic appearance of nosocomial legionnaires' disease after erythromycin treatment. 1991 Thorax pmid:1948796
Venkatesan P et al. A hospital study of community acquired pneumonia in the elderly. 1990 Thorax pmid:2356552
Fujii T et al. Long term effect of erythromycin therapy in patients with chronic Pseudomonas aeruginosa infection. 1995 Thorax pmid:8553295
Tsang KW et al. Clinical profiles of Chinese patients with diffuse panbronchiolitis. 1998 Thorax pmid:9741370
Guest PJ et al. Pulmonary Mycobacterium kansasii infection successfully treated with a regimen containing erythromycin. 1988 Thorax pmid:3420563
Brugiere O et al. Diffuse panbronchiolitis in an Asian immigrant. 1996 Thorax pmid:8977613
Marlin GE et al. Plasma and sputum erythromycin concentrations in chronic bronchitis. 1980 Thorax pmid:7434299
Koyama H and Geddes DM Erythromycin and diffuse panbronchiolitis. 1997 Thorax pmid:9404381
Sobradillo V et al. Antibiotic treatment in pneumonia due to Q fever. 1992 Thorax pmid:1585291
McCulloch AJ et al. Severe steroid responsive pneumonitis associated with pyoderma gangrenosum and ulcerative colitis. 1985 Thorax pmid:4023983
Rogers GB et al. Clinical measures of disease in adult non-CF bronchiectasis correlate with airway microbiota composition. 2013 Thorax pmid:23564400
Johnsson H and Niklasson PM Effects of some antibiotics of platelet function in vitro and in vivo. 1977 Thromb. Res. pmid:905975
Itoh T and Kasahara S Rat T lymphocyte progenitors in bone marrow can be induced to express more Thy 1. 1985 Thymus pmid:2865831
Bergan T [Erythromycin instead of tetracyclines to children]. 1978 Tidsskr. Nor. Laegeforen. pmid:684704
Høye S An extraordinary tale of an ordinary case. 2015 Tidsskr. Nor. Laegeforen. pmid:26130550
Loose LM et al. Adolescent with respiratory impairments and short-lived fever. 2015 Tidsskr. Nor. Laegeforen. pmid:26130549
Halstensen A et al. [Treatment of infections caused by group A beta-hemolytic streptococci]. 1990 Tidsskr. Nor. Laegeforen. pmid:2120791
Gulbrandsen P and Fugelli P [Bad custom]. 1991 Tidsskr. Nor. Laegeforen. pmid:2000597
Nesbakken T et al. [Chlamydial inclusion conjunctivitis in the newborn. 5 cases]. 1982 Tidsskr. Nor. Laegeforen. pmid:7157283
Ose L [Encephalitis associated with mycoplasma pneumoniae infection in children]. 1975 Tidsskr. Nor. Laegeforen. pmid:1145545
Lind O and Harthug S [Hearing loss after erythromycin therapy]. 1993 Tidsskr. Nor. Laegeforen. pmid:8211901
Brauteset LV et al. [Invasive pneumoccal disease in children in Oslo 1998-2004]. 2008 Tidsskr. Nor. Laegeforen. pmid:18552897
Aas K [Treatment of infections in allergic patients]. 1974 Tidsskr. Nor. Laegeforen. pmid:4820866
Volden G [Syphilis]. 1980 Tidsskr. Nor. Laegeforen. pmid:6992342
Lefsaker L et al. [Legionnaires' disease]. 1988 Tidsskr. Nor. Laegeforen. pmid:3353900
Holst-Larsen L [Antibacterial agents. 4. Erythromycin]. 1972 Tidsskr. Nor. Laegeforen. pmid:4657026
Hassel B [Acute hypothermia and adverse effects on the central nervous system during erythromycin therapy]. 1994 Tidsskr. Nor. Laegeforen. pmid:7915859
Afset JE and Maeland JA [Erythromycin and ciprofloxacin resistant Campylobacter jejuni]. 2001 Tidsskr. Nor. Laegeforen. pmid:11571989
Devriese L [Antibiotic sensitivity tests (author's transl)]. 1976 Tijdschr Diergeneeskd pmid:827819
Boswinkel M and Sloet van Oldruitenborgh-Oosterbaan MM [Diagnosis and therapy of Rhodococcus equi infection in the horse]. 2006 Tijdschr Diergeneeskd pmid:16989420
van der Toorn F and Lumeij JT [Streptococcus gallolyticus infections in racing pigeons, a literature review]. 2001 Tijdschr Diergeneeskd pmid:11227399
Schurgers M et al. [A case of toxic hepatitis]. 1974 Tijdschr Gastroenterol pmid:4454054
van der Lely N et al. [A child with Chlamydia trachomatis pneumonia]. 1993 Tijdschr Kindergeneeskd pmid:8266317
van der Kuy A et al. [The erythromycin group]. 1974 Tijdschr Ziekenverpl pmid:4499128
Ramos CJ and Antonetti DA The role of small GTPases and EPAC-Rap signaling in the regulation of the blood-brain and blood-retinal barriers. 2017 Tissue Barriers pmid:28632993
Onodera T et al. Effect of fluid and antibiotic administration on experimental fecal peritonitis. 1968 Tohoku J. Exp. Med. pmid:5715596
Kanemitsu K et al. Efficacy of amikacin combinations for nocardiosis. 2003 Tohoku J. Exp. Med. pmid:14649737
Hara T et al. Successful treatment of severe reflux esophagitis with erythromycin in a patient with progressive systemic sclerosis and proximal gastrectomy. 2006 Tokai J. Exp. Clin. Med. pmid:21302226
Partiarca PA et al. Outbreaks of pertussis in the United States: the Wisconsin experience. 1988 Tokai J. Exp. Clin. Med. pmid:3273611
MUNOZBLAZQUEZ J [ANTIBIOTIC-CORTISONE TREATMENT OF GENITAL INFLAMMATION]. 1964 Tokoginecol Pract pmid:14108914
Giuliano MW and Miller SJ Site-Selective Reactions with Peptide-Based Catalysts. 2016 Top Curr Chem pmid:26307403
DUBRA F [PATHOLOGY OF PULMONARY TUBERCULOSIS CAUSED BY RESISTANT BACTERIA]. 1963 Sep-Dec Torax pmid:14158172
DUBRA F [THE CURE OF PULMONARY TUBERCULOSIS CAUSED BY RESISTANT BACTERIA]. 1963 Sep-Dec Torax pmid:14158173
PALERMO FM [SECONDARY BACTERIAL RESISTANCE]. 1963 Sep-Dec Torax pmid:14159781
BARDIER A et al. [Results of infantile propiocine granulated for syrup in infections pathology in infants (Apropos of 71 cases)]. 1961 Toulouse Med pmid:13686911
BARDIER A et al. [CURRENT TREATMENT OF PLEURO-PULMONARY STAPHYLOCOCCAL INFECTIONS IN INFANTS (APROPOS OF 60 CASES)]. 1964 Toulouse Med pmid:14169371
Abdel-Hameid NA Protective role of dimethyl diphenyl bicarboxylate (DDB) against erythromycin induced hepatotoxicity in male rats. 2007 Toxicol In Vitro pmid:17267170
Tilmant K et al. Comparison of a genomic and a multiplex cell imaging approach for the detection of phospholipidosis. 2011 Toxicol In Vitro pmid:21515356
Peyre L et al. High-content screening imaging and real-time cellular impedance monitoring for the assessment of chemical's bio-activation with regards hepatotoxicity. 2015 Toxicol In Vitro pmid:26239606
Hayashi S et al. Characterization of multinuclear hepatocytes induced in rats by mitemcinal (GM-611), an erythromycin derivative. 2008 Toxicol Pathol pmid:18776165
Mahgoub A et al. Azithromycin and erythromycin ameliorate the extent of colonic damage induced by acetic acid in rats. 2005 Toxicol. Appl. Pharmacol. pmid:15885263
Gracia T et al. Modulation of steroidogenic gene expression and hormone production of H295R cells by pharmaceuticals and other environmentally active compounds. 2007 Toxicol. Appl. Pharmacol. pmid:17822730
Gant TW et al. In vivo induction of liver P-glycoprotein expression by xenobiotics in monkeys. 1995 Toxicol. Appl. Pharmacol. pmid:7645023
Dakhel Y and Jamali F Erythromycin potentiates PR interval prolonging effect of verapamil in the rat: a pharmacodynamic drug interaction. 2006 Toxicol. Appl. Pharmacol. pmid:16466760
Dujovne CA Liver cell culture toxicity and surfactant potency of erythromycin derivatives. 1975 Toxicol. Appl. Pharmacol. pmid:1135866
Sadrieh N and Thomas PE Characterization of rat cytochrome P450 isozymes involved in the covalent binding of cyclosporin A to microsomal proteins. 1994 Toxicol. Appl. Pharmacol. pmid:8048065
WORTH HM et al. INTRAGASTRIC INJECTION FOR TOXICITY STUDIES WITH NEWBORN RATS. 1963 Toxicol. Appl. Pharmacol. pmid:14082477
Kalsotra A et al. Expression and characterization of human cytochrome P450 4F11: Putative role in the metabolism of therapeutic drugs and eicosanoids. 2004 Toxicol. Appl. Pharmacol. pmid:15364545
Gaeta GB et al. Characterization of the effects of erythromycin estolate and erythromycin base on the excretory function of the isolated rat liver. 1985 Toxicol. Appl. Pharmacol. pmid:2992120
Flaman AS et al. The effect of interferon-α on the expression of cytochrome P450 3A4 in human hepatoma cells. 2011 Toxicol. Appl. Pharmacol. pmid:21466820