erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Watanabe M et al. | Role of CYP3A in bromperidol metabolism in rat in vitro and in vivo. | 1999 | Xenobiotica | pmid:10553724 |
Zallen RD and Curry JT | A study of antibiotic usage in compound mandibular fractures. | 1975 | J Oral Surg | pmid:1055204 |
Jobe DA et al. | Detection of borreliacidal antibodies in Lyme borreliosis patient sera containing antimicrobial agents. | 1999 | Clin. Diagn. Lab. Immunol. | pmid:10548588 |
Netherwood T et al. | Probiotics shown to change bacterial community structure in the avian gastrointestinal tract. | 1999 | Appl. Environ. Microbiol. | pmid:10543832 |
Aoki Y and Kao PN | Erythromycin inhibits transcriptional activation of NF-kappaB, but not NFAT, through calcineurin-independent signaling in T cells. | 1999 | Antimicrob. Agents Chemother. | pmid:10543746 |
Maeda K et al. | [A case of common variable immunodeficiency that responded to long-term erythromycin chemotherapy]. | 1999 | Nihon Kokyuki Gakkai Zasshi | pmid:10540836 |
Tobback K et al. | Micellar electrokinetic capillary chromatography of macrolide antibiotics. Separation of tylosin, erythromycin and their related substances. | 1999 | J Chromatogr A | pmid:10536850 |
Nicholas KC et al. | Periadenitis mucosa necrotica recurrens. | 1975 | J Oral Surg | pmid:1053656 |
Schmidtke LM and Carson J | Induction, characterisation and pathogenicity in rainbow trout Oncorhynchus mykiss (Walbaum) of Lactococcus garvieae L-forms. | 1999 | Vet. Microbiol. | pmid:10535774 |
Janier M | [Syphilis (except congenital syphilis)]. | 1999 Aug-Sep | Ann Dermatol Venereol | pmid:10530355 |
Sato A et al. | Effects of organic anions and vinblastine on biliary excretion of erythromycin in rats. | 1999 | Pharmacology | pmid:10529657 |
Yoh M et al. | Effect of subinhibitory concentrations of antimicrobial agents (quinolones and macrolide) on the production of verotoxin by enterohemorrhagic Escherichia coli O157:H7. | 1999 | Can. J. Microbiol. | pmid:10526400 |
Shortridge VD et al. | Prevalence of macrolide resistance mechanisms in Streptococcus pneumoniae isolates from a multicenter antibiotic resistance surveillance study conducted in the United States in 1994-1995. | 1999 | Clin. Infect. Dis. | pmid:10524961 |
Cocito C and Di Giambattista M | The in vitro binding of virginiamycin M to bacteria ribosomes and ribosomal subunits. | 1978 | Mol. Gen. Genet. | pmid:105240 |
Sheu BS et al. | A three-day course of intravenous omeprazole plus antibiotics for H. pylori-positive bleeding duodenal ulcer. | 1999 Jul-Aug | Hepatogastroenterology | pmid:10521999 |
Xue Q et al. | A multiplasmid approach to preparing large libraries of polyketides. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10518520 |
De Winter BY et al. | Effect of different prokinetic agents and a novel enterokinetic agent on postoperative ileus in rats. | 1999 | Gut | pmid:10517907 |
Yoshida H and Furuta T | [Tissue penetration properties of macrolide antibiotics--comparative tissue distribution of erythromycin-stearate, clarithromycin, roxithromycin and azithromycin in rats]. | 1999 | Jpn J Antibiot | pmid:10516929 |
Chantarotorn S et al. | Diffuse panbronchiolitis, the first case reports in Thailand. | 1999 | J Med Assoc Thai | pmid:10511794 |
Ball SE et al. | Population distribution and effects on drug metabolism of a genetic variant in the 5' promoter region of CYP3A4. | 1999 | Clin. Pharmacol. Ther. | pmid:10511065 |
Kinirons MT et al. | Failure of erythromycin breath test to correlate with midazolam clearance as a probe of cytochrome P4503A. | 1999 | Clin. Pharmacol. Ther. | pmid:10511057 |
McMullin ST et al. | Impact of a Web-based clinical information system on cisapride drug interactions and patient safety. | 1999 | Arch. Intern. Med. | pmid:10510994 |
Ahmad M et al. | Disposition kinetics of erythromycin in normal and experimentally-induced febrile rabbits. | 1999 Apr-Jun | Eur J Drug Metab Pharmacokinet | pmid:10510739 |
Khan SA et al. | Simultaneous detection of erythromycin-resistant methylase genes ermA and ermC from Staphylococcus spp. by multiplex-PCR. | 1999 | Mol. Cell. Probes | pmid:10508560 |
Oster P et al. | Patterns of macrolide resistance determinants among community-acquired Streptococcus pneumoniae isolates over a 5-year period of decreased macrolide susceptibility rates. | 1999 | Antimicrob. Agents Chemother. | pmid:10508033 |
Miossec-Bartoli C et al. | The new ketolide HMR3647 accumulates in the azurophil granules of human polymorphonuclear cells. | 1999 | Antimicrob. Agents Chemother. | pmid:10508024 |
Rosendal K et al. | Staphylococcus aureus strains isolated in Danish hospitals from January 1st, 1966, to December 31st, 1974. | 1976 | Acta Pathol Microbiol Scand B | pmid:1050144 |
Widdowson CA and Klugman KP | Molecular mechanisms of resistance to commonly used non-betalactam drugs in Streptococcus pneumoniae. | 1999 | Semin Respir Infect | pmid:10501313 |
Moreno M et al. | Clinical management of tacrolimus drug interactions in renal transplant patients. | 1999 | Transplant. Proc. | pmid:10500564 |
Zgoulli S et al. | Microencapsulation of erythromycin and clarithromycin using a spray-drying technique. | 1999 Sep-Oct | J Microencapsul | pmid:10499837 |
Azuma A and Kudoh S | [Diffuse panbronchiolitis: DPB]. | 1999 | Nippon Rinsho | pmid:10497417 |
Gibson EM et al. | Transfer of plasmid-mediated antibiotic resistance from streptococci to lactobacilli. | 1979 | J. Bacteriol. | pmid:104973 |
Cash P et al. | A proteomic analysis of erythromycin resistance in Streptococcus pneumoniae. | 1999 | Electrophoresis | pmid:10493130 |
Moore PA | Dental therapeutic indications for the newer long-acting macrolide antibiotics. | 1999 | J Am Dent Assoc | pmid:10492541 |
Kirsten D and Meister W | [Present possibilities of antibiotic therapy in chronic non-specific respiratory diseases (author's transl)]. | 1976 | Z Erkr Atmungsorgane | pmid:1049185 |
Wieckiewicz JA | Relationship between resistance to metallic ions and production of beta-lactamase in strains of Staphylococcus epidermidis. | 1976 | J Hyg Epidemiol Microbiol Immunol | pmid:1048968 |
Gómez-Lus R et al. | Is there an ecological relationship between rates of antibiotic resistance of species of the genus Streptococcus? The Spanish Surveillance Group for Respiratory Pathogens. | 1999 | J. Clin. Microbiol. | pmid:10488213 |
Sarisuta N et al. | Physico-chemical characterization of interactions between erythromycin and various film polymers. | 1999 | Int J Pharm | pmid:10486428 |
Cizman M et al. | Influence of increased macrolide consumption on macrolide resistance of common respiratory pathogens. | 1999 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:10482034 |
Wilson DJ et al. | Comparison of seven antibiotic treatments with no treatment for bacteriological efficacy against bovine mastitis pathogens. | 1999 | J. Dairy Sci. | pmid:10480091 |
Howard KB et al. | Azithromycin versus erythromycin for community-acquired pneumonia: a cost-minimization analysis. | 1999 | Am J Health Syst Pharm | pmid:10478989 |
Gabriëls M et al. | Densitometric thin layer chromatographic analysis of tretinoin and erythromycin in lotions for topical use in acne treatment. | 1999 | Eur J Pharm Biopharm | pmid:10477329 |
Madinier IM et al. | Resistance profile survey of 50 periodontal strains of Actinobacillus actinomyectomcomitans. | 1999 | J. Periodontol. | pmid:10476896 |
Rizzo G et al. | [Behavior of Vibrio cholerae strains of the biotype El Tor isolated in Apulia in 1973, in relation to various antibiotics and chemotherapeutics]. | 1975 May-Jun | Ann Sclavo | pmid:1047628 |
Mikasa K et al. | [Clinical application of the new action of macrolide preparations to respiratory diseases]. | 1999 | Nippon Naika Gakkai Zasshi | pmid:10475020 |
Syphilis: CDC recommended treatment schedules 1976. | 1976 | Prim. Care | pmid:1047450 | |
Sturm A et al. | Prokinetics in patients with gastroparesis: a systematic analysis. | 1999 Sep-Oct | Digestion | pmid:10473966 |
Mikamo H et al. | Adequate macrolide treatment schedules for uterine cervicitis caused by Chlamydia trachomatis. | 1999 Sep-Oct | Chemotherapy | pmid:10473928 |
Sofer D et al. | 'Subinhibitory' erythromycin represses production of Pseudomonas aeruginosa lectins, autoinducer and virulence factors. | 1999 Sep-Oct | Chemotherapy | pmid:10473921 |
Nawaz MS et al. | Biochemical and molecular characterization of erthromycin-resistant avian Staphylococcus spp. isolated from chickens. | 1999 | Poult. Sci. | pmid:10472846 |
Cross NA et al. | Antimicrobial susceptibility testing of Chlamydia trachomatis using a reverse transcriptase PCR-based method. | 1999 | Antimicrob. Agents Chemother. | pmid:10471587 |
De Azavedo JC et al. | Prevalence and mechanisms of macrolide resistance in clinical isolates of group A streptococci from Ontario, Canada. | 1999 | Antimicrob. Agents Chemother. | pmid:10471555 |
Huovinen P | Causes, diagnosis and treatment of pharyngitis. | 1999 Jun-Jul | Compr Ther | pmid:10470516 |
Di Lorenzo C et al. | Effect of sequential erythromycin and octreotide on antroduodenal manometry. | 1999 | J. Pediatr. Gastroenterol. Nutr. | pmid:10467994 |
Manners BT et al. | An investigation of antibiotic resistance of Staphylococcus aureus in general practice. | 1976 | Practitioner | pmid:1046672 |
Cerbo M and Vecchione R | [L-forms and pigment production in "Pseudomonas aeruginosa" (author's transl)]. | 1978 May-Jun | Ann Sclavo | pmid:104666 |
Ando M et al. | A new look at hypersensitivity pneumonitis. | 1999 | Curr Opin Pulm Med | pmid:10461534 |
Arpin C et al. | Emergence of mefA and mefE genes in beta-haemolytic streptococci and pneumococci in France. | 1999 | J. Antimicrob. Chemother. | pmid:10459823 |
Luna VA et al. | A variety of gram-positive bacteria carry mobile mef genes. | 1999 | J. Antimicrob. Chemother. | pmid:10459806 |
Odland BA et al. | Antimicrobial activity of gatifloxacin (AM-1155, CG5501), and four other fluoroquinolones tested against 2,284 recent clinical strains of Streptococcus pneumoniae from Europe, Latin America, Canada, and the United States. The SENTRY Antimicrobial Surveillance Group (Americas and Europe). | 1999 | Diagn. Microbiol. Infect. Dis. | pmid:10459483 |
Boyanova L et al. | Characteristics and trends in macrolide resistance among Helicobacter pylori strains isolated in Bulgaria over four years. | 1999 | Diagn. Microbiol. Infect. Dis. | pmid:10459482 |
Watanakunakorn C | Clindamycin therapy of Staphylococcus aureus endocarditis. Clinical relapse and development of resistance to clindamycin, lincomycin and erythromycin. | 1976 | Am. J. Med. | pmid:1045861 |
Grunt J and Krcméry V | Multiple drug-resistance in staphylococci, an analysis of all-nation computer-processed data. | 1976 | Zentralbl Bakteriol Orig A | pmid:1045837 |
Morales WJ et al. | Change in antibiotic resistance of group B streptococcus: impact on intrapartum management. | 1999 | Am. J. Obstet. Gynecol. | pmid:10454674 |
Tamaoki J et al. | Macrolide antibiotics protect against immune complex-induced lung injury in rats: role of nitric oxide from alveolar macrophages. | 1999 | J. Immunol. | pmid:10453038 |
Wang H et al. | Demethylation capacity of human fetal adrenal mitochondrial cytochrome P-450 in vitro. | 1999 | Zhongguo Yao Li Xue Bao | pmid:10452125 |
Cohen J et al. | Mediterranean spotted fever in pregnancy. | 1999 | Scand. J. Infect. Dis. | pmid:10447334 |
Vorland LH et al. | Interference of the antimicrobial peptide lactoferricin B with the action of various antibiotics against Escherichia coli and Staphylococcus aureus. | 1999 | Scand. J. Infect. Dis. | pmid:10447328 |
Jones KL et al. | The effect of erythromycin on gastric emptying is modified by physiological changes in the blood glucose concentration. | 1999 | Am. J. Gastroenterol. | pmid:10445530 |
Moss AJ et al. | A review of the cardiac systemic side-effects of antihistamines: ebastine. | 1999 | Clin. Exp. Allergy | pmid:10444238 |
Schiano P et al. | [Gastroparesis of central origin: usefulness of erythromycin]. | 1999 | Can J Anaesth | pmid:10442972 |
Limia A et al. | Five-year analysis of antimicrobial susceptibility of the Streptococcus milleri group. | 1999 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:10442424 |
Albini E et al. | Activity of aerosol thiamphenicol glycinate acetylcysteinate in a mouse model of S. pyogenes pneumonia. | 1999 | Arzneimittelforschung | pmid:10442213 |
Blackwell BA et al. | Oxidative deamination of hydrolyzed fumonisin B(1) (AP(1)) by cultures of Exophiala spinifera. | 1999 | Nat. Toxins | pmid:10441035 |
Kearney GC et al. | Structural elucidation studies of erythromycins by electrospray tandem mass spectrometry II. | 1999 | Rapid Commun. Mass Spectrom. | pmid:10440983 |
Sakai C et al. | Nocardia asteroides pneumonia, subcutaneous abscess and meningitis in a patient with advanced malignant lymphoma: successful treatment based on in vitro antimicrobial susceptibility. | 1999 | Intern. Med. | pmid:10440509 |
Drug interactions. | 1999 | Med Lett Drugs Ther | pmid:10436770 | |
Kumar A and Will EJ | Necrotizing fasciitis and Legionnaires' disease after combined renal and pancreatic transplantation: a penalty of overseas travel. | 1999 | Nephrol. Dial. Transplant. | pmid:10435897 |
Barone A et al. | Microbiotica associated with refractory periodontis. Prevalence and antibiotic susceptibility. | 1999 | Minerva Stomatol | pmid:10434536 |
Krecic-Shepard ME et al. | In vivo comparison of putative probes of CYP3A4/5 activity: erythromycin, dextromethorphan, and verapamil. | 1999 | Clin. Pharmacol. Ther. | pmid:10430108 |
Credito KL et al. | Activity of telithromycin (HMR 3647) against anaerobic bacteria compared to those of eight other agents by time-kill methodology. | 1999 | Antimicrob. Agents Chemother. | pmid:10428930 |
Giovanetti E et al. | Phenotypes and genotypes of erythromycin-resistant Streptococcus pyogenes strains in Italy and heterogeneity of inducibly resistant strains. | 1999 | Antimicrob. Agents Chemother. | pmid:10428916 |
Johnson MM et al. | Effect of carbon dioxide on testing of susceptibilities of respiratory tract pathogens to macrolide and azalide antimicrobial agents. | 1999 | Antimicrob. Agents Chemother. | pmid:10428903 |
Callréus T et al. | Changes in gastrointestinal motility influence the absorption of desmopressin. | 1999 | Eur. J. Clin. Pharmacol. | pmid:10424324 |
Bachmann K et al. | A study of the interaction between dirithromycin and astemizole in healthy adults. | 1997 Feb-Mar | Am J Ther | pmid:10423595 |
Okada J et al. | [Changes of antimicrobial susceptibility of anaerobic bacteria from clinical specimens (author's transl)]. | 1975 | Jpn J Antibiot | pmid:1042183 |
Cvetkovic M et al. | OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine. | 1999 | Drug Metab. Dispos. | pmid:10421612 |
Latorre G et al. | [Chlamydia pneumoniae pneumonia]. | 1998 Jan-Mar | Rev Med Univ Navarra | pmid:10420952 |
de Sousa G et al. | A multi-laboratory evaluation of cryopreserved monkey hepatocyte functions for use in pharmaco-toxicology. | 1999 | Chem. Biol. Interact. | pmid:10418972 |
Kearney JA et al. | In vitro activities of the oxazolidinone compounds linezolid (PNU-100766) and eperzolid (PNU-100592) against middle ear isolates of Streptococcus pneumoniae. | 1999 | Int. J. Antimicrob. Agents | pmid:10418759 |
Albini E et al. | In vitro antibacterial activity of thiamphenicol glycinate acetylcysteinate against respiratory pathogens. | 1999 | Arzneimittelforschung | pmid:10417871 |
Lee DO and Lee CD | Serotonin syndrome in a child associated with erythromycin and sertraline. | 1999 | Pharmacotherapy | pmid:10417041 |
Matsumoto H et al. | Sensitivity of fresh isolates of Haemophilus to current antibiotics. | 1975 | Jpn J Antibiot | pmid:1041598 |
Finegold SM | Antimicrobial therapy of anaerobic infections. | 1975 | Postgrad Med | pmid:1041514 |
Driessen JH | A computer study of bacterial resistance patterns to antibiotics. | 1975 | Chemotherapy | pmid:1041490 |
Lin CF and Chung TC | Cloning of erythromycin-resistance determinants and replication origins from indigenous plasmids of Lactobacillus reuteri for potential use in construction of cloning vectors. | 1999 | Plasmid | pmid:10413663 |
Wagenvoort JH et al. | How useful is the Chlamydia micro-immunofluorescence (MIF) test for the gynaecologist? | 1999 | Eur. J. Obstet. Gynecol. Reprod. Biol. | pmid:10413220 |
Drici MD et al. | Comparison of tegaserod (HTF 919) and its main human metabolite with cisapride and erythromycin on cardiac repolarization in the isolated rabbit heart. | 1999 | J. Cardiovasc. Pharmacol. | pmid:10413072 |
Messini M et al. | Bacteremia after dental treatment in mentally handicapped people. | 1999 | J. Clin. Periodontol. | pmid:10412852 |
Oguri T et al. | [Multiple drug resistance of Enterobacter-Serratia group isolated from clinical materials (author's transl)]. | 1975 | Jpn J Antibiot | pmid:1041281 |