erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Steigleder GK | [The effectiveness of neonatal ocular prophylactic treatment for preventing chlamydial or gonococcal conjunctivitis]. | 1989 | Z. Hautkr. | pmid:2741529 |
Rohde BT et al. | [Exterior use of erythromycin in acne]. | 1978 | Z. Hautkr. | pmid:152523 |
Dimitrov K et al. | [Clinical etiological findings in chlamydial urethritis in men]. | 1984 | Z. Hautkr. | pmid:6495799 |
Gerny H | [Experiences in dermatologic practice with combined external treatment of acne with benzoyl peroxide and erythromycin]. | 1984 | Z. Hautkr. | pmid:6235684 |
Rozman TA et al. | [Double-blind group comparison of topical meclocycline, erythromycin and placebo in the treatment of papulo-pustulosa acne]. | 1984 | Z. Hautkr. | pmid:6240840 |
Schmidt JB et al. | [Local acne therapy with erythromycin]. | 1982 | Z. Hautkr. | pmid:6461974 |
Ratzenhofer E et al. | [In-vitro inhibition of collagenase activity in epidermolysis bullosa hereditaria dystrophica]. | 1978 | Z. Hautkr. | pmid:216174 |
Freitag G et al. | [Report of experiences with the clinical trial of a liquid erythromycin-containing topical solution for the treatment of acne]. | 1983 | Z. Hautkr. | pmid:6221475 |
Schmidt JB et al. | [External erythromycin therapy of acne]. | 1983 | Z. Hautkr. | pmid:6229931 |
Dworsky P | [Effect of inhibitors of protein and nucleic acid synthesis on the shape of the nucleoid of Escherichia coli]. | 1974 | Z. Allg. Mikrobiol. | pmid:4142904 |