erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Reinert RR et al. | In vitro activities of the new ketolide antibiotics HMR 3004 and HMR 3647 against Streptococcus pneumoniae in Germany. | 1998 | Antimicrob. Agents Chemother. | pmid:9624505 |
Roblin PM and Hammerschlag MR | In vitro activity of a new ketolide antibiotic, HMR 3647, against Chlamydia pneumoniae. | 1998 | Antimicrob. Agents Chemother. | pmid:9624507 |
Souli M et al. | In vitro activity of BAY 12-8039, a new fluoroquinolone, against species representative of respiratory tract pathogens. | 1998 | Int. J. Antimicrob. Agents | pmid:9624540 |
Wirsing von König CH et al. | Factors influencing the spread of pertussis in households. | 1998 | Eur. J. Pediatr. | pmid:9625336 |
Wandel C et al. | Effect of CYP3A inhibition on vesnarinone metabolism in humans. | 1998 | Clin. Pharmacol. Ther. | pmid:9630823 |
Stassi DL et al. | Ethyl-substituted erythromycin derivatives produced by directed metabolic engineering. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9636144 |
Novaes AB et al. | Immediate implants placed into infected sites: a histomorphometric study in dogs. | 1998 May-Jun | Int J Oral Maxillofac Implants | pmid:9638015 |
Havlik J and Holý M | [Erythromycin stearate Spofa--coated tablets for pediatric practice]. | 1976 | Cesk Pediatr | pmid:963828 |
Shimatani T | Involvement of cholinergic motor neurons in pharmacological regulation of gastrointestinal motility by glucagon in conscious dogs. | 1997 Aug-Oct | J Smooth Muscle Res | pmid:9639019 |
Oyarzún E et al. | Antibiotic treatment in preterm labor and intact membranes: a randomized, double-blinded, placebo-controlled trial. | 1998 May-Jun | J Matern Fetal Med | pmid:9642605 |
Jeffreys AJ and Craig IW | Analysis of proteins synthesized in mitochondria of cultured mammalian cells. An assessment of current approaches and problems in interpretation. | 1976 | Eur. J. Biochem. | pmid:964267 |
Kobashi Y et al. | [A case of Listeria monocytogenes sepsis in an elderly who survived]. | 1998 | Kansenshogaku Zasshi | pmid:9642946 |
Hoshino K et al. | [Antimicrobial activity of macrolides against clinical isolates]. | 1998 | Jpn J Antibiot | pmid:9644599 |
Nakae M et al. | [Drug susceptibility of clinically isolated Helicobacter pylori]. | 1998 | Jpn J Antibiot | pmid:9644601 |
Shryock TR et al. | Antimicrobial susceptibility of Moraxella bovis. | 1998 | Vet. Microbiol. | pmid:9646479 |
Pasco J | What has the patient been taking? | 1998 | Aust Fam Physician | pmid:9648320 |
Gharaibeh MN et al. | Effect of multiple doses of rifampin on the [14C N-methyl] erythromycin breath test in healthy male volunteers. | 1998 | J Clin Pharmacol | pmid:9650537 |
Suzuki Y et al. | [Antimicrobial activities of clindamycin against clinical isolated Streptococcus pneumoniae]. | 1997 | Jpn J Antibiot | pmid:9651606 |
Wehbeh HA et al. | Single-dose azithromycin for Chlamydia in pregnant women. | 1998 | J Reprod Med | pmid:9653697 |
O'Halloran HS et al. | Leber's neuroretinitis in a patient with serologic evidence of Bartonella elizabethae. | 1998 | Retina (Philadelphia, Pa.) | pmid:9654422 |
Orden B et al. | Erythromycin resistance of Streptococcus pyogenes in Madrid. | 1998 | Pediatr. Infect. Dis. J. | pmid:9655536 |
Kuyucu N et al. | Comparison of oral erythromycin, local administration of streptomycin and placebo therapy for nonsuppurative Bacillus Calmette-Guérin lymphadenitis. | 1998 | Pediatr. Infect. Dis. J. | pmid:9655549 |
Rangel-Lugo M et al. | Prevention of antibiotic residues in veal calves fed colostrum. | 1998 | J. Am. Vet. Med. Assoc. | pmid:9656021 |
[Streptococcus pyogenes and resistance to macrolides: experience at Monza]. | 1998 Jan-Feb | Minerva Pediatr. | pmid:9658791 | |
Azuma A et al. | Preventive effect of erythromycin on experimental bleomycin-induced acute lung injury in rats. | 1998 | Thorax | pmid:9659353 |
Schultz MJ et al. | Erythromycin inhibits tumor necrosis factor alpha and interleukin 6 production induced by heat-killed Streptococcus pneumoniae in whole blood. | 1998 | Antimicrob. Agents Chemother. | pmid:9660992 |
Kadota J et al. | Inhibitory effect of erythromycin on superoxide anion production by human neutrophils primed with granulocyte-colony stimulating factor. | 1998 | Antimicrob. Agents Chemother. | pmid:9661038 |
D'Souza P et al. | A comparative study of therapeutic response of patients with clinical chancroid to ciprofloxacin, erythromycin, and cotrimoxazole. | 1998 | Sex Transm Dis | pmid:9662762 |
Gamaleia NB and Levashev VS | [Biological properties and mechanisms of development of bacteria resistant to fusidin, erythromycin and chloramphenicol]. | 1978 | Zh. Mikrobiol. Epidemiol. Immunobiol. | pmid:96638 |
Verhagen MA et al. | Effects of a new motilide, ABT-229, on gastric emptying and postprandial antroduodenal motility in healthy volunteers. | 1997 | Aliment. Pharmacol. Ther. | pmid:9663833 |
Griffin RG | Dipolar recoupling in MAS spectra of biological solids. | 1998 | Nat. Struct. Biol. | pmid:9665180 |
Yagi Y et al. | Characterization of a small plasmid determining resistance to erythromycin, lincomycin, and vernamycin Balpha in a strain of Streptococcus sanguis isolated from dental plaque. | 1978 | Antimicrob. Agents Chemother. | pmid:96738 |
As incidence increases CDC recommends 1976 treatment schedule for syphilis. | 1976 | Pa Med | pmid:967481 | |
Rathgeber J and Burchardi H | [Use of the antibiotic erythromycin in intestinal motility disorders]. | 1998 | Anaesthesist | pmid:9676314 |
Hayakawa H et al. | Diffuse panbronchiolitis and rheumatoid arthritis-associated bronchiolar disease: similarities and differences. | 1998 | Intern. Med. | pmid:9678682 |
Enomoto F et al. | [Evaluation of methods of macrolide antibiotic administration in experimental otitis media of rats]. | 1997 | Jpn J Antibiot | pmid:9678980 |
Ikeda K et al. | [Effect of macrolide antibiotics on ion transport of nasal mucosal epithelium]. | 1997 | Jpn J Antibiot | pmid:9678982 |
Wessel F | [Peri-anesthesia allergies to antibiotics]. | 1998 | Allerg Immunol (Paris) | pmid:9684043 |
Stassi D et al. | A genetically engineered strain of Saccharopolyspora erythraea that produces 6,12-dideoxyerythromycin A as the major fermentation product. | 1998 | Appl. Microbiol. Biotechnol. | pmid:9684306 |
Tripathi S et al. | Ketolide resistance conferred by short peptides. | 1998 | J. Biol. Chem. | pmid:9685347 |
Bowman ED et al. | Impact of erythromycin on respiratory colonization of Ureaplasma urealyticum and the development of chronic lung disease in extremely low birth weight infants. | 1998 | Pediatr. Infect. Dis. J. | pmid:9686728 |
Hamilton-Miller JM and Shah S | Comparative in-vitro activity of ketolide HMR 3647 and four macrolides against gram-positive cocci of known erythromycin susceptibility status. | 1998 | J. Antimicrob. Chemother. | pmid:9687104 |
Gaudreau C and Gilbert H | Antimicrobial resistance of clinical strains of Campylobacter jejuni subsp. jejuni isolated from 1985 to 1997 in Quebec, Canada. | 1998 | Antimicrob. Agents Chemother. | pmid:9687415 |
Petrakis J et al. | Enhancement of gastric emptying of solids by erythromycin in patients with Roux-en-Y gastrojejunostomy. | 1998 | Arch Surg | pmid:9687997 |
Ehrenpreis ED et al. | Which form of erythromycin should be used to treat gastroparesis? A pharmacokinetic analysis. | 1998 | Aliment. Pharmacol. Ther. | pmid:9690728 |
Staunton J | Combinatorial biosynthesis of erythromycin and complex polyketides. | 1998 | Curr Opin Chem Biol | pmid:9691072 |
Kanfer I et al. | Analysis of macrolide antibiotics. | 1998 | J Chromatogr A | pmid:9691324 |
Segura-Corrales J et al. | [Cat-scratch disease. Presentation of 2 cases in a family with serologic follow-up and discussion of diagnostic methods]. | 1998 | Rev Clin Esp | pmid:9691742 |
Weissman KJ et al. | Origin of starter units for erythromycin biosynthesis. | 1998 | Biochemistry | pmid:9692995 |
Milla E et al. | Bilateral optic papillitis following mycoplasma pneumoniae pneumonia. | 1998 | Ophthalmologica | pmid:9693295 |