erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Ergotism D004881 4 associated lipids
Urethral Diseases D014522 4 associated lipids
Streptococcal Infections D013290 4 associated lipids
Otitis Media, Suppurative D010035 4 associated lipids
Periapical Diseases D010483 4 associated lipids
Esophagitis, Peptic D004942 4 associated lipids
Psittacosis D009956 4 associated lipids
Mycetoma D008271 4 associated lipids
Pleural Diseases D010995 4 associated lipids
Adrenocortical Carcinoma D018268 4 associated lipids
Chancroid D002602 4 associated lipids
Agammaglobulinemia D000361 4 associated lipids
Fetal Membranes, Premature Rupture D005322 4 associated lipids
Varicose Ulcer D014647 4 associated lipids
Balanitis D001446 4 associated lipids
Conjunctivitis, Inclusion D003235 4 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Sexually Transmitted Diseases, Bacterial D015231 5 associated lipids
Chorioamnionitis D002821 5 associated lipids
Anemia, Hemolytic, Autoimmune D000744 5 associated lipids
Myasthenia Gravis D009157 5 associated lipids
Vibrio Infections D014735 5 associated lipids
Intestinal Pseudo-Obstruction D007418 5 associated lipids
Prostatitis D011472 5 associated lipids
Toxoplasmosis, Animal D014124 5 associated lipids
Dyspepsia D004415 5 associated lipids
Rickettsia Infections D012282 5 associated lipids
Hand Dermatoses D006229 5 associated lipids
Anemia, Hypochromic D000747 5 associated lipids
Asthenia D001247 5 associated lipids
Lyme Disease D008193 5 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Erythema Nodosum D004893 5 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Pyoderma D011711 5 associated lipids
Lung Diseases, Interstitial D017563 5 associated lipids
Otitis D010031 5 associated lipids
Sigmoid Neoplasms D012811 5 associated lipids
Endocarditis, Bacterial D004697 5 associated lipids
Laryngitis D007827 5 associated lipids
Intraoperative Complications D007431 5 associated lipids
Endometritis D004716 6 associated lipids
Trisomy D014314 6 associated lipids
Skin Ulcer D012883 6 associated lipids
Pleural Effusion, Malignant D016066 6 associated lipids
Nocardia Infections D009617 6 associated lipids
Intestinal Obstruction D007415 6 associated lipids
Xerostomia D014987 6 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
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Authors Title Published Journal PubMed Link
Vanden Boom TJ Recent developments in the molecular genetics of the erythromycin-producing organism Saccharopolyspora erythraea. 2000 Adv. Appl. Microbiol. pmid:12876795
Vining LC Antibiotic tolerance in producer organisms. 1979 Adv. Appl. Microbiol. pmid:94753
Lechevalier HA Production of the same antibiotics by members of different genera of microorganisms. 1975 Adv. Appl. Microbiol. pmid:52998
Waksman SA Successes and failures in the search for antibiotics. 1969 Adv. Appl. Microbiol. pmid:4195044
Williams GJ and Thorson JS Natural product glycosyltransferases: properties and applications. 2009 Adv. Enzymol. Relat. Areas Mol. Biol. pmid:18990828
Mortensen JE and McDowell T Streptococcus pyogenes: resistant, tolerant, neither or both? 1995 Adv. Exp. Med. Biol. pmid:8718606
Ferraro AL et al. The antimicrobial susceptibility of Streptococcus pyogenes isolates from the Philadelphia area. 1995 Adv. Exp. Med. Biol. pmid:8718607
Garber NC et al. Regulation of lectin production by the human pathogens Pseudomonas aeruginosa and Chromobacterium violaceum: effects of choline, trehalose, and ethanol. 2011 Adv. Exp. Med. Biol. pmid:21618111
Siekmeier R et al. Inhalation of macrolides: a novel approach to treatment of pulmonary infections. 2015 Adv. Exp. Med. Biol. pmid:25252902
Klein TW et al. Legionella pneumophila infection and cytokine production. 1992 Adv. Exp. Med. Biol. pmid:1414610
Yang YH et al. Opacity factor inhibition test for typing group A beta-haemolytic streptococcus strains and antibiotic susceptibility. 1997 Adv. Exp. Med. Biol. pmid:9331595
Jasir A and Schalén C Erythromycin resistance phenotypes in Swedish clinical isolates of group A streptococci. 1997 Adv. Exp. Med. Biol. pmid:9331689
Savoia D et al. Group A streptococci. Erythromycin resistance and penicillin tolerance. 1997 Adv. Exp. Med. Biol. pmid:9331690
Vicarini H et al. Analysis of regulatory region of ermAM genes in streptococci and enterococci highly resistant to macrolides and lincosamides. 1997 Adv. Exp. Med. Biol. pmid:9331702
Dansette PM et al. Drug interactions with macrolide antibiotics: specificity of pseudo-suicide inhibition and induction of cytochrome P-450. 1986 Adv. Exp. Med. Biol. pmid:3490132
Yayan J and Rasche K Growing Antibiotic Resistance in Fatal Cases of Staphylococcal Pneumonia in the Elderly. Adv. Exp. Med. Biol. pmid:26747068
Lartey PA et al. New developments in macrolides: structures and antibacterial and prokinetic activities. 1994 Adv. Pharmacol. pmid:8080820
Garrett RA and Wittmann HG Structure of bacterial ribosomes. 1973 Adv. Protein Chem. pmid:4589667
Dully FE Streptococcal epidemic in an aircraft carrier. 1973 Aerosp Med pmid:4201795
Ogwal S and Xide TU Bioavailability and stability of erythromycin delayed release tablets. 2001 Afr Health Sci pmid:12789122