erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Otitis Media, Suppurative D010035 4 associated lipids
Streptococcal Infections D013290 4 associated lipids
Psittacosis D009956 4 associated lipids
Mycetoma D008271 4 associated lipids
Periapical Diseases D010483 4 associated lipids
Esophagitis, Peptic D004942 4 associated lipids
Adrenocortical Carcinoma D018268 4 associated lipids
Pleural Diseases D010995 4 associated lipids
Conjunctivitis, Inclusion D003235 4 associated lipids
Chancroid D002602 4 associated lipids
Agammaglobulinemia D000361 4 associated lipids
Fetal Membranes, Premature Rupture D005322 4 associated lipids
Varicose Ulcer D014647 4 associated lipids
Balanitis D001446 4 associated lipids
Limb Deformities, Congenital D017880 4 associated lipids
Mycobacterium avium-intracellulare Infection D015270 4 associated lipids
Myasthenia Gravis D009157 5 associated lipids
Anemia, Hemolytic, Autoimmune D000744 5 associated lipids
Intestinal Pseudo-Obstruction D007418 5 associated lipids
Vibrio Infections D014735 5 associated lipids
Prostatitis D011472 5 associated lipids
Rickettsia Infections D012282 5 associated lipids
Toxoplasmosis, Animal D014124 5 associated lipids
Dyspepsia D004415 5 associated lipids
Hand Dermatoses D006229 5 associated lipids
Anemia, Hypochromic D000747 5 associated lipids
Lyme Disease D008193 5 associated lipids
Ureaplasma Infections D016869 5 associated lipids
Asthenia D001247 5 associated lipids
Erythema Nodosum D004893 5 associated lipids
Desulfovibrionaceae Infections D045824 5 associated lipids
Diabetic Neuropathies D003929 5 associated lipids
Pyoderma D011711 5 associated lipids
Lung Diseases, Interstitial D017563 5 associated lipids
Otitis D010031 5 associated lipids
Endocarditis, Bacterial D004697 5 associated lipids
Laryngitis D007827 5 associated lipids
Intraoperative Complications D007431 5 associated lipids
Sigmoid Neoplasms D012811 5 associated lipids
Boutonneuse Fever D001907 5 associated lipids
Chorioamnionitis D002821 5 associated lipids
Sexually Transmitted Diseases, Bacterial D015231 5 associated lipids
Pleural Effusion, Malignant D016066 6 associated lipids
Alveolitis, Extrinsic Allergic D000542 6 associated lipids
Intestinal Obstruction D007415 6 associated lipids
Xerostomia D014987 6 associated lipids
Pneumonia, Mycoplasma D011019 6 associated lipids
Tuberculosis, Multidrug-Resistant D018088 6 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Pericarditis D010493 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Palmieri C et al. Interspecies mobilization of an ermT-carrying plasmid of Streptococcus dysgalactiae subsp. equisimilis by a coresident ICE of the ICESa2603 family. 2013 J. Antimicrob. Chemother. pmid:22949621
Wasels F et al. Clostridium difficile erm(B)-containing elements and the burden on the in vitro fitness. 2013 J. Med. Microbiol. pmid:23741023
Kawai Y et al. Nationwide surveillance of macrolide-resistant Mycoplasma pneumoniae infection in pediatric patients. 2013 Antimicrob. Agents Chemother. pmid:23716043
González-Hein G et al. [Molecular analysis of fluoroquinolones and macrolides resistance in Campylobacter jejuni isolates from humans, bovine and chicken meat]. 2013 Rev Chilena Infectol pmid:23677151
Adhikari MD et al. Membrane-directed high bactericidal activity of (gold nanoparticle)-polythiophene composite for niche applications against pathogenic bacteria. 2013 Adv Healthc Mater pmid:23184755
Utsunomiya S et al. Critical residues in the transmembrane helical bundle domains of the human motilin receptor for erythromycin binding and activity. 2013 Regul. Pept. pmid:23142315
Li YJ et al. EM, EM703 inhibit NF-kB activation induced by oxidative stress from diesel exhaust particle in human bronchial epithelial cells: importance in IL-8 transcription. 2013 Pulm Pharmacol Ther pmid:23291319
Berghaus LJ et al. Mutant prevention concentration and mutant selection window for 10 antimicrobial agents against Rhodococcus equi. 2013 Vet. Microbiol. pmid:23915992
Gold RM and Lawhon SD Incidence of inducible clindamycin resistance in Staphylococcus pseudintermedius from dogs. 2013 J. Clin. Microbiol. pmid:24025915
Henson AM et al. Detection of Streptococcus pyogenes by use of Illumigene group A Streptococcus assay. 2013 J. Clin. Microbiol. pmid:24048538
Wieczorek K et al. Prevalence and antimicrobial resistance of Campylobacter spp. isolated from poultry carcasses in Poland. 2013 J. Food Prot. pmid:23905805
Di Salvo A et al. Pharmacokinetics and residue depletion of erythromycin in rainbow trout Oncorhynchus mykiss (Walbaum). 2013 J. Fish Dis. pmid:24118016
Avci O et al. A comparison between the effectiveness of erythromycin, single-dose clarithromycin and topical fusidic acid in the treatment of erythrasma. 2013 J Dermatolog Treat pmid:21923567
Pohl O et al. Effects of erythromycin at steady-state concentrations on the pharmacokinetics of ulipristal acetate. 2013 J Clin Pharm Ther pmid:24102384
Kelley C et al. Antimicrobial activity of various 4- and 5-substituted 1-phenylnaphthalenes. 2013 Eur J Med Chem pmid:23314053
González-Pleiter M et al. Toxicity of five antibiotics and their mixtures towards photosynthetic aquatic organisms: implications for environmental risk assessment. 2013 Water Res. pmid:23399078
Lermite E et al. Complications after pancreatic resection: diagnosis, prevention and management. 2013 Clin Res Hepatol Gastroenterol pmid:23415988
Atamanyuk D et al. Vectorization efforts to increase Gram-negative intracellular drug concentration: a case study on HldE-K inhibitors. 2013 J. Med. Chem. pmid:23445125
Gomes DL et al. SubMICs of penicillin and erythromycin enhance biofilm formation and hydrophobicity of Corynebacterium diphtheriae strains. 2013 J. Med. Microbiol. pmid:23449875
Yang M et al. Macrolides for diffuse panbronchiolitis. 2013 Cochrane Database Syst Rev pmid:23450579
Schafer F et al. Antimicrobial susceptibility and genetic characteristics of Propionibacterium acnes isolated from patients with acne. 2013 Int. J. Dermatol. pmid:23432195
Chen Y et al. Significant decrease of broth viscosity and glucose consumption in erythromycin fermentation by dynamic regulation of ammonium sulfate and phosphate. 2013 Bioresour. Technol. pmid:23500575
Whitehead TR and Cotta MA Stored swine manure and swine faeces as reservoirs of antibiotic resistance genes. 2013 Lett. Appl. Microbiol. pmid:23297734
Basak R and Bandyopadhyay R Encapsulation of hydrophobic drugs in Pluronic F127 micelles: effects of drug hydrophobicity, solution temperature, and pH. 2013 Langmuir pmid:23472840
Hao H et al. Mutational and transcriptomic changes involved in the development of macrolide resistance in Campylobacter jejuni. 2013 Antimicrob. Agents Chemother. pmid:23274667
Yang J et al. Characterization of chicken cytochrome P450 1A4 and 1A5: inter-paralog comparisons of substrate preference and inhibitor selectivity. 2013 Comp. Biochem. Physiol. C Toxicol. Pharmacol. pmid:23474502
Capanna F et al. Antibiotic resistance patterns among group B Streptococcus isolates: implications for antibiotic prophylaxis for early-onset neonatal sepsis. 2013 Swiss Med Wkly pmid:23572445
Yadav DK et al. Failure of secondary prophylaxis with erythromycin in rheumatic heart disease. 2013 Indian Pediatr pmid:24382905
Chen Y et al. Controlling the feed rate of glucose and propanol for the enhancement of erythromycin production and exploration of propanol metabolism fate by quantitative metabolic flux analysis. 2013 Bioprocess Biosyst Eng pmid:23361182
Melnik BC and Schmitz G Are therapeutic effects of antiacne agents mediated by activation of FoxO1 and inhibition of mTORC1? 2013 Exp. Dermatol. pmid:23800068
Gaudreau C et al. Campylobacter coli outbreak in men who have sex with men, Quebec, Canada, 2010-2011. 2013 Emerging Infect. Dis. pmid:23647786
Kjær S et al. Ultrasound-guided drainage of subcutaneous abscesses on the trunk is feasible. 2013 Dan Med J pmid:23651712
Ragazzi E et al. Saliva concentration of amoxicillin, erythromycin, and ciprofloxacin in outpatients: a comparison between the young and the elderly. 2013 J Chemother pmid:23684362
Rasamiravaka T et al. Evaluation of methicillin-resistant Staphylococcus aureus nasal carriage in Malagasy patients. 2013 J Infect Dev Ctries pmid:23592641
Nakajima T et al. Absence of intervening sequences and point mutations in the V domain within 23S rRNA in Campylobacter lari isolates. 2013 Folia Microbiol. (Praha) pmid:23595231
Ma X et al. Characterization of erythromycin-resistant Streptococcus pneumoniae isolates causing invasive diseases in Chinese children. 2013 Chin. Med. J. pmid:23595388
Hinarejos P et al. The use of erythromycin and colistin-loaded cement in total knee arthroplasty does not reduce the incidence of infection: a prospective randomized study in 3000 knees. 2013 J Bone Joint Surg Am pmid:23636182
Gao X et al. Total synthesis of 6-deoxyerythronolide B via C-C bond-forming transfer hydrogenation. 2013 J. Am. Chem. Soc. pmid:23464668
Roberts DW What is the role of antibiotic-containing cement in total knee arthroplasty? 2013 J Bone Joint Surg Am pmid:23636201
Sun W et al. [Glycosyl isomerization based on the biosynthesis of natural-product sugar from microorganism]. 2013 Yao Xue Xue Bao pmid:23672013
Jiang M et al. The logic, experimental steps, and potential of heterologous natural product biosynthesis featuring the complex antibiotic erythromycin A produced through E. coli. 2013 J Vis Exp pmid:23354010
Elens L et al. CYP3A4 intron 6 C>T SNP (CYP3A4*22) encodes lower CYP3A4 activity in cancer patients, as measured with probes midazolam and erythromycin. 2013 Pharmacogenomics pmid:23327575
Mueck W et al. Co-administration of rivaroxaban with drugs that share its elimination pathways: pharmacokinetic effects in healthy subjects. 2013 Br J Clin Pharmacol pmid:23305158
Lins RX et al. Antimicrobial resistance and virulence traits of Enterococcus faecalis from primary endodontic infections. 2013 J Dent pmid:23851130
Gonçalves A et al. Antimicrobial resistance in faecal enterococci and Escherichia coli isolates recovered from Iberian wolf. 2013 Lett. Appl. Microbiol. pmid:23336611
Rożynek E et al. Emergence of macrolide-resistant Campylobacter strains in chicken meat in Poland and the resistance mechanisms involved. 2013 Foodborne Pathog. Dis. pmid:23638847
Grabowicz M et al. Dominant negative lptE mutation that supports a role for LptE as a plug in the LptD barrel. 2013 J. Bacteriol. pmid:23316047
Dubey D et al. A report on infection dynamics of inducible clindamycin resistance of Staphylococcus aureus isolated from a teaching hospital in India. 2013 Asian Pac J Trop Biomed pmid:23593595
Marcellin E et al. Saccharopolyspora erythraea's genome is organised in high-order transcriptional regions mediated by targeted degradation at the metabolic switch. 2013 BMC Genomics pmid:23324121
Baltar F et al. Bacterial versus archaeal origin of extracellular enzymatic activity in the Northeast Atlantic deep waters. 2013 Microb. Ecol. pmid:23015014