erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Gomez JR and Gomez G | Comparative trial of erythromycin and tetracycline in common infections found in general practice. | 1968 | Br J Clin Pract | pmid:4880249 |
Linnane AW et al. | The biogenesis of mitochondria. V. Cytoplasmic inheritance of erythromycin resistance in Saccharomyces cerevisiae. | 1968 | Proc. Natl. Acad. Sci. U.S.A. | pmid:5238670 |
Malski M | [Effect of penicillin, aureomycin, chloramphenicol and erythromycin on tubercle bacilli]. | 1968 | Gruzlica | pmid:4974660 |
Kanno M et al. | [Study on progressive muscular dystrophy. 1. Influence of the various drugs on serum enzyme activity and the degree of disability]. | 1968 | Iryo | pmid:5717702 |
Cairella M and Marasà G | [The chemoantibiotics in infections of the bile ducts]. | 1968 | Clin Ter | pmid:4982819 |
Breitfellner G et al. | [Staphylococci in the Vienna area. Epidemiology, antibiotic sensitivity and therapeutic aspects]. | 1968 | Wien. Klin. Wochenschr. | pmid:5188335 |
Sotaniemi E and Huhti E | Bronchial asthma and toxic hepatitis. | 1968 | Ann Allergy | pmid:5644356 |
Tereshin IM and Belousova II | [Effect of some antibiotics on the transfer of the resistance to tetracycline and chloramphenicol by means of the episome factor (Rtf)]. | 1968 | Antibiotiki | pmid:4298603 |
Jakubowski A et al. | [Experimental studies in vivo on the effect upon Trepomena pallidum of some antibiotics other than penicillin]. | 1968 Jan-Feb | Przegl Dermatol | pmid:4867335 |
Schirger A et al. | Erythromycin for prophylaxis prior to oral surgery in patients allergic to panicillin. | 1968 Jan-Feb | Northwest Dent | pmid:5240271 |
Meeroff M | [Treatment of intestinal amebiasis with erythromycin stearate. Parastitic study of fecal material]. | 1968 Jan-Jun | Bol Chil Parasitol | pmid:5705124 |
Freidel C and Deidier C | [The role of Abboticine in stomatologic hospital practice. (Study and report on 26 cases)]. | 1968 Jul-Aug | Ann Odontostomatol (Lyon) | pmid:5683852 |
Mielech R et al. | [Studies on the effect of most frequently used antibiotics on the course of syphilitic infection]. | 1968 Mar-Apr | Przegl Dermatol | pmid:4877997 |
Fleurette J | [The sensitivity of pathogenic staphylococci of human origin to two recent antibiotics: cephalotin and lincomycin]. | 1968 May-Jun | Ann. Biol. Clin. (Paris) | pmid:5681856 |
Morbidelli R et al. | [Evolution of antibiotic sensitivity of 336 staphylococcal strains from 1956-1967]. | 1968 Nov-Dec | G Batteriol Virol Immunol | pmid:4907246 |
Videau D | [Penetration, site and mode of action of antibiotics in bacteria]. | 1968 Nov-Dec | Biol Med (Paris) | pmid:4238452 |
Sanders E | Lincomycin versus erythromycin: a choice or an echo. | 1969 | Ann. Intern. Med. | pmid:4886921 |
Demarco PV | NMR study of some erythromycin aglycones. A conformational and configurational analysis. | 1969 | J. Antibiot. | pmid:5346042 |
Fernando WL | Erythromycin in early syphilis. | 1969 | Br J Vener Dis | pmid:5346418 |
Abdallah A et al. | Erythromycin stearate in intestinal amoebiasis. | 1969 | J Egypt Med Assoc | pmid:5346517 |
Nelson JD | Antibiotic treatment of pertussis. | 1969 | Pediatrics | pmid:5346626 |
de Almeida AJ | [Clinico-therapeutic observations on the use of erythromycin ethylsuccinate in infections in ambulatory pediatric practice]. | 1969 | Rev Bras Med | pmid:5347024 |
Hughes WT and Collier RN | Streptococcal pharyngitis. Evaluation of erythromycin, erythromycin-sulfas, and sulfamethoxazole (possible antagonism between erythromycin and sulfas). | 1969 | Am. J. Dis. Child. | pmid:5348368 |
Jessen O et al. | Changing staphylococci and staphylococcal infections. A ten-year study of bacteria and cases of bacteremia. | 1969 | N. Engl. J. Med. | pmid:5194719 |
Bals MG and FilipescÅ S | The antistaphylococcal activity of Rifampicin. | 1969 | Arzneimittelforschung | pmid:5194845 |
Annear DI and Grubb WB | Sponaneous loss of resistance to kanamycin and other antibiotics in methicillin-resistant cultures of Staphylococcus aureus. | 1969 | Med. J. Aust. | pmid:5196123 |
Mel'nikova VM et al. | [Experience in the use of lincomycin in the treatment of staphylococcal infections in traumatologic and orthopedic patients]. | 1969 | Antibiotiki | pmid:5196670 |
Stottmeier KD et al. | New approach for the evaluation of antimycobacterial drug combinations in vitro (the laboratory model man). | 1969 | Appl Microbiol | pmid:5198127 |
Bhaskaran CS and Jayakar PA | Antibiotic resistant staphylococci from cases and carriers. | 1969 | Pathol Microbiol (Basel) | pmid:5198670 |
Nakahara T et al. | [Effect of drug administration on the child with progressive muscular dystrophy]. | 1969 | Iryo | pmid:5364983 |
Bebe M | [Therapeutic indications in staphylococcal pleursy and pneumonia. 114 cases]. | 1969 | Ann Pediatr (Paris) | pmid:5365506 |
Beale GH | A note on the inheritance of erythromycin-resistance in Paramecium aurelia. | 1969 | Genet. Res. | pmid:5367381 |
Grieco MH | Hypersensitivity abdominal pain induced by erythromycin propionate estolate. | 1969 | Med Times | pmid:5763354 |
A second look at lincomycin (lincocin). | 1969 | Med Lett Drugs Ther | pmid:5368405 | |
Crawford LV and Roane J | Use of erythromycin ethyl succinate in allergic children. | 1969 | Ann Allergy | pmid:5765653 |
Koroleva VG et al. | [Effect of acid protective coating on absorption of erythromycin at oral administration]. | 1969 | Antibiotiki | pmid:5371175 |
Wyman JB et al. | Pancreatic excretion of erythromycin and kanamycin. Comparison of results obtained via a Thomas cannula and a duodenopancreaticopyelostoma in dogs. | 1969 | Arch Surg | pmid:5766288 |
Martin WJ | Antibiotic therapy in the management of lymphangitis. | 1969 | Mod Treat | pmid:5377627 |
Barlow AJ and Chattaway FW | Observations on the carriage of Candida albicans in man. | 1969 | Br. J. Dermatol. | pmid:5767062 |
Krasnogolovets VN | [Pseudomembraneous enterocolitis in the treatment of patients with antibiotics]. | 1969 | Antibiotiki | pmid:5378166 |
VeÄs RA and Storozhev IA | [Experimental study of erythromycin phosphate]. | 1969 | Antibiotiki | pmid:5768791 |
[A report about drug side effects. X]. | 1969 | Lakartidningen | pmid:5378762 | |
Slawiński W et al. | [Correlation between the structure and effect in the group of derivatives of erythromycin A]. | 1969 | Acta Pol Pharm | pmid:5380496 |
Pádua Mde A | [Treatment of chronic intestinal amebiasis using non-absorbent erythromycin stearate (case study)]. | 1969 | Rev Bras Med | pmid:5381894 |
Rebrova RN and Serebrennikova II | [Fungi of the genus Candida in the diphtheria carrier state]. | 1969 | Zh. Mikrobiol. Epidemiol. Immunobiol. | pmid:5382615 |
Lagache G and Proye C | [Clinical trial of erythromycin stearate in surgery (44 cases)]. | 1969 | Lille Med | pmid:5384131 |
Gingold EB et al. | Biogenesis of mitochondria, X. Reassortment of the cytoplasmic genetic determinants for respiratory competence and erythromycin resistance in Saccharomyces cerevisiae. | 1969 | Genetics | pmid:5384489 |
Iwamoto HK and Brennan WR | The effect of demeclocycline, methacycline, and erythromycin on tooth color in the rat. | 1969 | Toxicol. Appl. Pharmacol. | pmid:4975609 |
Wiersum J et al. | A comparison of erythromycin and methacycline in the treatment of common bacterial infections. | 1969 | Curr Ther Res Clin Exp | pmid:4976333 |
Bordácová J and Výmola F | [Sensitivity of Corynebacterium acnes toward antibiotics]. | 1969 | Arzneimittelforschung | pmid:4976652 |
Klimov AN et al. | [Comparative study of DNA of resistant and sensitive to antibiotic combination hemolytic streptococci]. | 1969 | Antibiotiki | pmid:4976745 |
Oleinick NL and Corcoran JW | Two types of binding of erythromycin to ribosomes from antibiotic-sensitive and -resistant Bacillus subtilis 168. | 1969 | J. Biol. Chem. | pmid:4976759 |
Kaplan K and Weinstein L | Diphtheroid infections of man. | 1969 | Ann. Intern. Med. | pmid:4976893 |
Sluga-Gasser E et al. | [Inflammatory diseases of the nervous system. Therapy of encephalitis and myelitis]. | 1969 | Bibl Psychiatr Neurol | pmid:4332890 |
Holloway WJ et al. | Pasteurella multocida infection in man. Report of 21 cases. | 1969 | Am. J. Clin. Pathol. | pmid:4976987 |
Takeuchi K | [Study on experimental shigellosis: relationship between the proliferation of Shigella bacilli in the intestine and the intestinal flora in mice]. | 1969 | Nihon Densenbyo Gakkai Zasshi | pmid:4977192 |
Lobene RR et al. | Effect of erythromycin on dental plaque and plaque forming microorganisms of man. | 1969 | J. Periodontol. | pmid:5255346 |
Goldman M and Pearson AH | Postdébridement bacterial flora and antibiotic sensitivity. | 1969 | Oral Surg. Oral Med. Oral Pathol. | pmid:5260664 |
Stahl SS et al. | Gingival healing. V. The effects of antibiotics administered during the early stages of repair. | 1969 | J. Periodontol. | pmid:5260865 |
Stone NH et al. | Empirical selection of antibiotics for hand infections. | 1969 | J Bone Joint Surg Am | pmid:4307419 |
Tereshin IM | [Mechanism of action of mitomycin C on genetic transformation of hemolytic Streptococci]. | 1969 | Antibiotiki | pmid:4982962 |
Loire R et al. | [Present developmental aspect of infectious endocarditis. According to hospital statistics of 103 consecutive cases collected in the last 12 years]. | 1969 | Sem Hop | pmid:4308671 |
Serebrennikova II | [Correlation between sensitivity of diphtheria bacteria to antibiotics and the presence of fungi of the Candida order]. | 1969 | Antibiotiki | pmid:4982964 |
Nishida M et al. | Studies on microbial degradation of carbenicillin. | 1969 | J. Antibiot. | pmid:4310240 |
Stephens VC et al. | A study of the behavior of propionyl erythromycin in blood by a new chromatographic method. | 1969 | J. Antibiot. | pmid:4983351 |
McCracken GH et al. | Antimicrobial therapy in theoy and practice. I. Clinical pharmacology. | 1969 | J. Pediatr. | pmid:4310466 |
Saslaw S et al. | Therapy of staphylococcal infections in monkeys. IV. Further comparison of triacetyloleandomycin and erythromycins. | 1969 | Appl Microbiol | pmid:4984259 |
Bass JW et al. | Antimicrobial treatment of pertussis. | 1969 | J. Pediatr. | pmid:4310467 |
Sallai S et al. | [Experimental studies on the intralamellar use of antibiotics]. | 1969 | Klin Monbl Augenheilkd | pmid:4311239 |
Toala P et al. | Susceptibility of group D streptococcus (enterococcus) to 21 antibiotics in vitro, with special reference to species differences. | 1969 | Am. J. Med. Sci. | pmid:4984452 |
Gauze GF | [Current methods of determination of the sensitivity of bacteria to antibiotics and their significance for rational antibiotic therapy]. | 1969 | Antibiotiki | pmid:4311307 |
Scholz O and Mothes W | [Tracheotomy from the surgical and bacteriological viewpoint]. | 1969 | Zentralbl Chir | pmid:4984512 |
Smith I et al. | The genetics of ribosomes in Bacillus subtilis. | 1969 | Cold Spring Harb. Symp. Quant. Biol. | pmid:4985892 |
Ruczaj Z et al. | On the release of enzymes upon lysozyme treatment of Streptomyces. | 1969 | Acta Biochim. Pol. | pmid:4312597 |
Blumberg N | Penicillin-resistant gonorrhea. | 1969 | J. Urol. | pmid:5189316 |
Raska B and Hradcová L | [The significance of the acid-base balance in pyelonephritis in childhood before and after operative intervention]. | 1969 | Monatsschr Kinderheilkd | pmid:4914869 |
Gare M | Egg-yolk reaction of Staphylococcus pyogenes. | 1969 | Pathology | pmid:5209498 |
da Silveira MH et al. | ["In vitro" effects of erythromycin estearate on Shigella and enteropathogenic groups of Escherichia coli]. | 1969 | Hospital (Rio J) | pmid:4916598 |
Briedigkeit H and Precht K | [Therapeutic suggestions on antibiotic therapy in patients with and without renal function disorders]. | 1969 | Dtsch Gesundheitsw | pmid:4916951 |
Cerná J et al. | The effect of antibiotics on the coded binding of peptidyl-tRNA to the ribosome and on the transfer of the peptidyl residue to puromycin. | 1969 | Eur. J. Biochem. | pmid:4891613 |
Grekova GN | [Sensitivity of Proteus vulgaris, isolated from patients with acute disorders of gastro-intestinal tract, to different antibiotics and furacillin]. | 1969 | Antibiotiki | pmid:4891714 |
Brovtsyna AV | [Study of sensitivity of antibiotics of microbes from the genus Shigella]. | 1969 | Antibiotiki | pmid:4891715 |
Kirschmann C and Davis BD | Phenotypic suppression in Escherichia coli by chloramphenicol and other reversible inhibitors of the ribosome. | 1969 | J. Bacteriol. | pmid:4891806 |
Tanaka N et al. | Mechanism of inhibition of protein synthesis by fusidic acid and related steroidal antibiotics. | 1969 | J. Biochem. | pmid:4892538 |
Whelan JP and Pugh IM | Sensitivity to spiramycin of thromycin-resistant strains of Staphylococcus aureus isolated from clinical sources. | 1969 | Med. J. Aust. | pmid:4893256 |
Olson CL | Bacterial flora of the conjunctiva and lid margin. Effects of parenteral trisulfapyramidines and topical tetracycline and erythromycin. | 1969 | Arch. Ophthalmol. | pmid:4894275 |
Murata M et al. | [Studies on josamycin. 4. Effect on Rickettsia orientalis and Miyagawanella psittaci]. | 1969 | Jpn J Antibiot | pmid:4895368 |
Myers WH | A comparative trial of three proprietary antibiotic preparations used in the treatment of acute infections. | 1969 | Br J Clin Pract | pmid:4895652 |
Grainger GJ | Erythromycin estolate in general practice. A comparative trial of two dosage forms. | 1969 | Practitioner | pmid:4895696 |
Passent J | [The effect of antibiotics on protein synthesis]. | 1969 | Postepy Biochem. | pmid:4895752 |
de Santana AF | [Ethyl succinate erythromycin and trisulphapyridine combination in the treatment of respiratory infections in pediatric outpatients]. | 1969 | Hospital (Rio J) | pmid:5306432 |
Gabor M and Hotchkiss RD | Differences in rate of phenotypic expression in separated strands of pneumococcal transforming DNA and evidence for change of reading direction. | 1969 | Genetics | pmid:4390535 |
Bestani WJ | [An erythromycin-trisulfapyrimidine combination in genitourinary infections]. | 1969 | Hospital (Rio J) | pmid:5306490 |
Kuriaki K et al. | [New antibiotics, Josamycin. VI. Study on absorption and distribution of Josamycin]. | 1969 | Jpn J Antibiot | pmid:5306999 |
Wense G | [Postoperative enterocolitis]. | 1969 | Zentralbl Chir | pmid:4391871 |
Zadvorniak PV and BronshteÄn RE | [Microflora of lungs in pneumonias of infants and its sensitivity to antibiotics]. | 1969 | Antibiotiki | pmid:4391893 |
de Oliveira CA | [Therapeutic experience in the use of erythromycin stearate in chronic intestinal amebiasis]. | 1969 | Hospital (Rio J) | pmid:5307522 |
Miniti A et al. | [Comparative study of antibiotic activity in bacterial infections in hospital practice]. | 1969 | Hospital (Rio J) | pmid:5307637 |
Bowman FW | Microbial contamination of antibiotic ophthalmic ointments. | 1969 | J Pharm Sci | pmid:4305340 |
Charlton RW | Recent advances in antibiotics. | 1969 | S. Afr. Med. J. | pmid:4305557 |