erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Segatore B et al. | In vitro interaction of usnic acid in combination with antimicrobial agents against methicillin-resistant Staphylococcus aureus clinical isolates determined by FICI and ΔE model methods. | 2012 | Phytomedicine | pmid:22119041 |
Sugimoto T et al. | Synthesis and structure-activity relationship of a novel class of 15-membered macrolide antibiotics known as '11a-azalides'. | 2012 | Bioorg. Med. Chem. | pmid:22925450 |
De Francesco MA et al. | Phenotypes, genotypes, serotypes and molecular epidemiology of erythromycin-resistant Streptococcus agalactiae in Italy. | 2012 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:22120421 |
Sugimoto T et al. | Synthesis and antibacterial activity of 6-O-(heteroaryl-isoxazolyl)propynyl 2-fluoro ketolides. | 2012 | Bioorg. Med. Chem. Lett. | pmid:22858102 |
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März A et al. | Fluorescence dye as novel label molecule for quantitative SERS investigations of an antibiotic. | 2012 | Anal Bioanal Chem | pmid:21822777 |
Jaglic Z et al. | Distribution, characterization and genetic bases of erythromycin resistance in staphylococci and enterococci originating from livestock. | 2012 | Zoonoses Public Health | pmid:21843202 |
Zaknoon F et al. | Antibacterial properties of an oligo-acyl-lysyl hexamer targeting Gram-negative species. | 2012 | Antimicrob. Agents Chemother. | pmid:22751534 |
Shiu WK et al. | Antibacterial acylphloroglucinols from Hypericum olympicum. | 2012 | J. Nat. Prod. | pmid:21899267 |
Gant CM et al. | Serotype distribution and antimicrobial resistance of invasive pneumococcal disease strains in the Comunidad Valenciana, Spain, during the winter of 2009-2010: low PCV7 coverage and high levofloxacin resistance. | 2012 | Antimicrob. Agents Chemother. | pmid:22751535 |
Shi JG et al. | The effect of CYP3A4 inhibition or induction on the pharmacokinetics and pharmacodynamics of orally administered ruxolitinib (INCB018424 phosphate) in healthy volunteers. | 2012 | J Clin Pharmacol | pmid:21602517 |
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Bosnar M et al. | N'-substituted-2'-O,3'-N-carbonimidoyl bridged macrolides: novel anti-inflammatory macrolides without antimicrobial activity. | 2012 | J. Med. Chem. | pmid:22697905 |
Yiannakopoulou E et al. | Pharmacological modulation of oxidative stress response in minimally invasive surgery: systematic review. | 2012 | Surg Laparosc Endosc Percutan Tech | pmid:22678313 |
Pollett S et al. | Campylobacter antimicrobial resistance in Peru: a ten-year observational study. | 2012 | BMC Infect. Dis. | pmid:22898609 |
Licona-Cassani C et al. | Reconstruction of the Saccharopolyspora erythraea genome-scale model and its use for enhancing erythromycin production. | 2012 | Antonie Van Leeuwenhoek | pmid:22847261 |
Calcium channel blockers + macrolides: elderly patients hospitalised for low blood pressure. | 2012 | Prescrire Int | pmid:22852287 | |
Kim EY et al. | The effectiveness of erythromycin in reducing stent-related tissue hyperplasia: an experimental study with a rat esophageal model. | 2012 | Acta Radiol | pmid:22855416 |
Oldenburg M et al. | TLR13 recognizes bacterial 23S rRNA devoid of erythromycin resistance-forming modification. | 2012 | Science | pmid:22821982 |
Feng Z et al. | Unidirectional peristaltic movement in multisite drug binding pockets of AcrB from molecular dynamics simulations. | 2012 | Mol Biosyst | pmid:22825052 |
Cetin M et al. | Clarithromycin-Induced Long QT Syndrome: A Case Report. | 2012 | Case Rep Med | pmid:22489247 |
Perry DM et al. | Identification and characterization of protein phosphatase 2C activation by ceramide. | 2012 | J. Lipid Res. | pmid:22615346 |
Geddes BA and Oresnik IJ | Genetic characterization of a complex locus necessary for the transport and catabolism of erythritol, adonitol and L-arabitol in Sinorhizobium meliloti. | 2012 | Microbiology (Reading, Engl.) | pmid:22609752 |
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Ocular prophylaxis for gonococcal ophthalmia neonatorum: reaffirmation recommendation statement. | 2012 | Am Fam Physician | pmid:22335221 | |
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