erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Warhurst DC | Chloroquine-erythromycin potentiation in P. berghei. | 1977 | Ann Trop Med Parasitol | pmid:335993 |
Khan B et al. | Plasmodium falciparum sensitivity to erythromycin and 4-aminoquinoline combinations in vitro. | 1991 | Ann Trop Med Parasitol | pmid:1796864 |
Mazur E et al. | Susceptibility to selected antibiotics of Streptococcus pneumoniae and Streptococcus pyogenes strains isolated from patients with respiratory tract infections. | 1999 | Ann Univ Mariae Curie Sklodowska Med | pmid:11205800 |
JESKE J et al. | [AN INVESTIGATION INTO SOME PHARMACODYNAMIC PROPERTIES OF ERYTHROMYCINUM BASICUM]. | 1963 | Ann Univ Mariae Curie Sklodowska Med | pmid:14232847 |
Nerlo H et al. | [Solubilizers of erythromycin A cyclic carbonate L-aspartate]. | 1980 | Ann Univ Mariae Curie Sklodowska Med | pmid:7349059 |
Nerlo H et al. | [Chemical synthesis of erythromycin A cyclic carbonate L-aspartate tablets]. | 1980 | Ann Univ Mariae Curie Sklodowska Med | pmid:7349060 |
Ghali R et al. | Erythromycin-associated ergotamine intoxication: arteriographic and electrophysiologic analysis of a rare cause of severe ischemia of the lower extremities and associated ischemic neuropathy. | 1993 | Ann Vasc Surg | pmid:8391300 |
Lim HS et al. | Legionnaires' disease--report of Singapore's first local case. | 1986 | Ann. Acad. Med. Singap. | pmid:3551784 |
Ng SK et al. | Ophthalmia neonatorum--the Middle Road Hospital perspective. | 1987 | Ann. Acad. Med. Singap. | pmid:3128155 |
Jorro G et al. | Anaphylaxis to erythromycin. | 1996 | Ann. Allergy Asthma Immunol. | pmid:8970433 |
Delgado LF et al. | Evaluation of the potential cardiotoxicity of the antihistamines terfenadine, astemizole, loratadine, and cetirizine in atopic children. | 1998 | Ann. Allergy Asthma Immunol. | pmid:9564984 |
Solensky R et al. | Clinical approach to penicillin-allergic patients: a survey. | 2000 | Ann. Allergy Asthma Immunol. | pmid:10752918 |
Klausner MA | Astemizole use with erythromycin. | 1999 | Ann. Allergy Asthma Immunol. | pmid:10582723 |
Leiding JW et al. | Successful sirolimus graded dose challenge in an erythromycin-allergic patient. | 2012 | Ann. Allergy Asthma Immunol. | pmid:23010239 |
Fleurette J | [The sensitivity of pathogenic staphylococci of human origin to two recent antibiotics: cephalotin and lincomycin]. | 1968 May-Jun | Ann. Biol. Clin. (Paris) | pmid:5681856 |
Guo Y et al. | The draft genomes and investigation of serotype distribution, antimicrobial resistance of group B Streptococcus strains isolated from urine in Suzhou, China. | 2018 | Ann. Clin. Microbiol. Antimicrob. | pmid:29945615 |
Azrad M et al. | Antimicrobial susceptibility of Campylobacter jejuni and Campylobacter coli: comparison between Etest and a broth dilution method. | 2018 | Ann. Clin. Microbiol. Antimicrob. | pmid:29792197 |
Su WJ et al. | [Evaluation of an experimental animal model allowing the study of the cecal microflora in the hamster, antagonistic to clostridium difficile]. | 1986 Jan-Feb | Ann. Inst. Pasteur Microbiol. | pmid:3674782 |
Moyen EN et al. | [Modification of intestinal colonization and translocation of Campylobacter jejuni by erythromycin and an extract of Lactobacillus acidophilus in axenic mice]. | 1986 Mar-Apr | Ann. Inst. Pasteur Microbiol. | pmid:3122638 |
Arthur M et al. | Heterogeneity of genes conferring high-level resistance to erythromycin by inactivation in enterobacteria. | 1986 Mar-Apr | Ann. Inst. Pasteur Microbiol. | pmid:3322168 |
Patel AM et al. | Statin toxicity from macrolide antibiotic coprescription: a population-based cohort study. | 2013 | Ann. Intern. Med. | pmid:23778904 |
Redington K et al. | Erythromycin and valproate interaction. | 1992 | Ann. Intern. Med. | pmid:1567109 |
Sanders E | Lincomycin versus erythromycin: a choice or an echo. | 1969 | Ann. Intern. Med. | pmid:4886921 |
GIBSON CD et al. | The treatment of bacterial pneumonia with erythromycin: a controlled clinical study. | 1954 | Ann. Intern. Med. | pmid:13171794 |
Wei N | Flurbiprofen and cutaneous vasculitis. | 1990 | Ann. Intern. Med. | pmid:2138443 |
Gantz NM et al. | Pseudomembranous colitis associated with erythromycin. | 1979 | Ann. Intern. Med. | pmid:517887 |
Edelstein PH et al. | Legionella wadsworthii species nova: a cause of human pneumonia. | 1982 | Ann. Intern. Med. | pmid:6756238 |
Metzger AL | Gonococcal arthritis complicating gonorrheal pharyngitis. | 1970 | Ann. Intern. Med. | pmid:4989317 |
Spencer WH et al. | Rheumatic fever chemoprophylaxis and penicillin-resistant gingival organisms. | 1970 | Ann. Intern. Med. | pmid:4990937 |
AUSTRIAN R and GOLD J | PNEUMOCOCCAL BACTEREMIA WITH ESPECIAL REFERENCE TO BACTEREMIC PNEUMOCOCCAL PNEUMONIA. | 1964 | Ann. Intern. Med. | pmid:14156606 |
Edelstein PH | Antimicrobial chemotherapy for Legionnaires disease: time for a change. | 1998 | Ann. Intern. Med. | pmid:9729189 |
McCloskey RV et al. | The 1970 epidemic of diphtheria in San Antonio. | 1971 | Ann. Intern. Med. | pmid:4999285 |
Neu HC | New macrolide antibiotics: azithromycin and clarithromycin. | 1992 | Ann. Intern. Med. | pmid:1310839 |
McCloskey RV et al. | Treatment of diphtheria carriers: benzathine penicillin, erythromycin, and clindamycin. | 1974 | Ann. Intern. Med. | pmid:4215352 |
Tolman KG et al. | Chemical structure of erythromycin and hepatotoxicity. | 1974 | Ann. Intern. Med. | pmid:4834945 |
Salyer IL and Cynamon MH | Letter: Isoniazid. | 1974 | Ann. Intern. Med. | pmid:4843588 |
Berk SL | New macrolide antibiotics. | 1992 | Ann. Intern. Med. | pmid:1386966 |
BUNN P et al. | Staphylococci: on the ubiquitous nature of human infections and their control by antimicrobial agents, singly or in combination. | 1958 | Ann. Intern. Med. | pmid:13488219 |
Wadhwa NK et al. | Intraperitoneal erythromycin for gastroparesis. | 1991 | Ann. Intern. Med. | pmid:2014956 |
Perlman DM et al. | Persistent Campylobacter jejuni infections in patients infected with the human immunodeficiency virus (HIV). | 1988 | Ann. Intern. Med. | pmid:3348562 |
Meyer RD et al. | Legionnaires' disease: unusual clinical and laboratory features. | 1980 | Ann. Intern. Med. | pmid:6996551 |
Horvitz RA et al. | Savings from generic prescriptions. A study of 33 pharmacies in Rochester, New York. | 1975 | Ann. Intern. Med. | pmid:166584 |
Bulger RJ and Sherris JC | Decreased incidence of antibiotic resistance among Staphylococcus aureus. A study in a university hospital over a 9-year period. | 1968 | Ann. Intern. Med. | pmid:5188901 |
Steere AC et al. | Antibiotic therapy in Lyme disease. | 1980 | Ann. Intern. Med. | pmid:6967272 |
Mansoor GA et al. | Azithromycin-induced acute interstitial nephritis. | 1993 | Ann. Intern. Med. | pmid:8395778 |
Snavely SR and Hodges GR | The neurotoxicity of antibacterial agents. | 1984 | Ann. Intern. Med. | pmid:6329054 |
Hoppes WL and Lerner PI | Nonenterococcal group-D streptococcal endocarditis caused by Streptococcus bovis. | 1974 | Ann. Intern. Med. | pmid:4422602 |
Swartz MN | Clinical aspects of Legionnaires' disease. | 1979 | Ann. Intern. Med. | pmid:434624 |
Winn WC et al. | Macroscopic pathology of the lungs in Legionnaires' disease. | 1979 | Ann. Intern. Med. | pmid:434632 |
McCabe RE et al. | Prosthetic valve endocarditis caused by Legionella pneumophila. | 1984 | Ann. Intern. Med. | pmid:6703545 |