erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Ogungbenro K et al. | A semi-mechanistic gastric emptying model for the population pharmacokinetic analysis of orally administered acetaminophen in critically ill patients. | 2011 | Pharm. Res. | pmid:20949310 |
Tachecà I et al. | Electrogastrography in experimental pigs: the influence of gastrointestinal injury induced by dextran sodium sulphate on porcine gastric erythromycin-stimulated myoelectric activity. | 2011 | Neuro Endocrinol. Lett. | pmid:22167215 |
Yuan H et al. | [The effect of erythromycin on transforming growth factor-β(1) and secretory leukocyte proteinase inhibitor in a rat model of chronic obstructive pulmonary disease]. | 2011 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:22041779 |
Watanabe I et al. | Combined effect of disopyramide and erythromycin on ventricular repolarization in dogs with complete atrioventricular block. | 2011 | Int Heart J | pmid:22188715 |
RodrÃguez C et al. | [Resistance phenotypes and genotypes of Streptococcus pyogenes clinical isolates in Chile over a 10-year period]. | 2011 | Rev Med Chil | pmid:22215392 |
Mak PJ et al. | Defining CYP3A4 structural responses to substrate binding. Raman spectroscopic studies of a nanodisc-incorporated mammalian cytochrome P450. | 2011 | J. Am. Chem. Soc. | pmid:21207936 |
Ren GW et al. | Rapid detection of point mutations in domain V of the 23S rRNA gene in erythromycin-resistant Campylobacter isolates by pyrosequencing. | 2011 | Foodborne Pathog. Dis. | pmid:21166562 |
Srinivasan U et al. | Identification of a novel keyhole phenotype in double-disk diffusion assays of clindamycin-resistant erythromycin-sensitive strains of Streptococcus agalactiae. | 2011 | Microb. Drug Resist. | pmid:21166574 |
Khan NW et al. | Antimicrobial activity of erythromycin and clarithromycin against clinical isolates of Escherichia coli, Staphylococcus aureus, Klebsiella and Proteus by disc diffusion method. | 2011 | Pak J Pharm Sci | pmid:21190914 |
Sonnevend à et al. | Lack of correlation between the 257C-to-T mutation in the gyrA gene and clinical severity of Campylobacter jejuni infection in a region of high incidence of ciprofloxacin resistance. | 2011 | Scand. J. Infect. Dis. | pmid:21905953 |
Jessick AM et al. | Optimization of analytical methods to improve detection of erythromycin from water and sediment. | 2011 | J Environ Sci Health B | pmid:21877980 |
Lee CY et al. | Identification and treatment of bisphosphonate-associated actinomycotic osteonecrosis of the jaws. | 2011 | Implant Dent | pmid:21881516 |
Tazi A et al. | Invasive group B streptococcal infections in adults, France (2007-2010). | 2011 | Clin. Microbiol. Infect. | pmid:21883671 |
Fenoll A et al. | Increase in serotype 19A prevalence and amoxicillin non-susceptibility among paediatric Streptococcus pneumoniae isolates from middle ear fluid in a passive laboratory-based surveillance in Spain, 1997-2009. | 2011 | BMC Infect. Dis. | pmid:21910891 |
Maezono H et al. | Antibiofilm effects of azithromycin and erythromycin on Porphyromonas gingivalis. | 2011 | Antimicrob. Agents Chemother. | pmid:21911560 |
Lehtopolku M et al. | Ribosomal mutations as the main cause of macrolide resistance in Campylobacter jejuni and Campylobacter coli. | 2011 | Antimicrob. Agents Chemother. | pmid:21911571 |
Drago L et al. | Macrolide resistance and in vitro selection of resistance to antibiotics in Lactobacillus isolates. | 2011 | J. Microbiol. | pmid:21887650 |
Li MJ et al. | High electrochemiluminescence of a new water-soluble iridium(III) complex for determination of antibiotics. | 2011 | Analyst | pmid:20944848 |
Haenni M et al. | ermB-mediated erythromycin resistance in Streptococcus uberis from bovine mastitis. | 2011 | Vet. J. | pmid:20667752 |
You L et al. | Dynamic multi-component covalent assembly for the reversible binding of secondary alcohols and chirality sensing. | 2011 | Nat Chem | pmid:22109274 |
Bilk S et al. | Antimicrobial susceptibilities and occurrence of resistance genes in bovine Helcococcus ovis isolates. | 2011 | Vet. Microbiol. | pmid:21131144 |
Zou X et al. | An assessment of seed quality on erythromycin production by recombinant Saccharopolyspora erythraea strain. | 2011 | Bioresour. Technol. | pmid:21134745 |
Palmieri C et al. | Different genetic elements carrying the tet(W) gene in two human clinical isolates of Streptococcus suis. | 2011 | Antimicrob. Agents Chemother. | pmid:21115784 |
Bosnjakovic A et al. | Poly(amidoamine) dendrimer-erythromycin conjugates for drug delivery to macrophages involved in periprosthetic inflammation. | 2011 | Nanomedicine | pmid:21059404 |
Shingate BB et al. | Stereoselective synthesis and antimicrobial activity of steroidal C-20 tertiary alcohols with thiazole/pyridine side chain. | 2011 | Eur J Med Chem | pmid:21664730 |
Panigaj M et al. | Expression of prion protein in mouse erythroid progenitors and differentiating murine erythroleukemia cells. | 2011 | PLoS ONE | pmid:21912705 |
Buendia J et al. | Preparation of diastereomerically pure dilignol model compounds. | 2011 | Chemistry | pmid:22076640 |
Hoa PT et al. | Antibiotic contamination and occurrence of antibiotic-resistant bacteria in aquatic environments of northern Vietnam. | 2011 | Sci. Total Environ. | pmid:21669325 |
Maragno AL et al. | ISG15 modulates development of the erythroid lineage. | 2011 | PLoS ONE | pmid:22022510 |
Joao EC et al. | Group B Streptococcus in a cohort of HIV-infected pregnant women: prevalence of colonization, identification and antimicrobial susceptibility profile. | 2011 | Scand. J. Infect. Dis. | pmid:21671824 |
Kreft A et al. | JAK2-V617F-mutated myeloproliferative neoplasms reveal different allele burden within hematopoietic cell lineages: a microdissection study of bone marrow trephine biopsies. | 2011 | Virchows Arch. | pmid:22006129 |
Zaed AM and Sutherland A | Total synthesis of clavaminol A, C and H. | 2011 | Org. Biomol. Chem. | pmid:21879135 |
Fry DE | Colon preparation and surgical site infection. | 2011 | Am. J. Surg. | pmid:21429471 |
Taillon MP et al. | Potentially new isobaric metabolite of fluvastatin observed by LC-MS/MS during incurred sample analysis. | 2011 | Bioanalysis | pmid:21877892 |
de Morais e Silva FA et al. | Rosacea fulminans in pregnancy with ocular perforation. | 2011 | J Dtsch Dermatol Ges | pmid:21366860 |
Serisier DJ and Martin ML | Long-term, low-dose erythromycin in bronchiectasis subjects with frequent infective exacerbations. | 2011 | Respir Med | pmid:21367595 |
Almofti YA et al. | Impact of erythromycin resistance on the virulence properties and fitness of Campylobacter jejuni. | 2011 | Microb. Pathog. | pmid:21377522 |
Luo DQ et al. | In vitro activities of erythromycin, tetracycline and levofloxacin alone and in dual combinations against ureaplasma spp. | 2011 | Chemotherapy | pmid:21430380 |
Heath AP et al. | An algorithm for efficient identification of branched metabolic pathways. | 2011 | J. Comput. Biol. | pmid:21999288 |
Ho PL et al. | Changes in nasopharyngeal carriage and serotype distribution of antibiotic-resistant Streptococcus pneumoniae before and after the introduction of 7-valent pneumococcal conjugate vaccine in Hong Kong. | 2011 | Diagn. Microbiol. Infect. Dis. | pmid:22000087 |
Wu JC and Sung JJ | Pharmacologic therapy for nonvariceal upper gastrointestinal bleeding. | 2011 | Gastrointest. Endosc. Clin. N. Am. | pmid:21944417 |
Nakamura PA et al. | Antimicrobial resistance profiles and genetic characterisation of macrolide resistant isolates of Streptococcus agalactiae. | 2011 | Mem. Inst. Oswaldo Cruz | pmid:21537668 |
Shaala LA et al. | Brominated arginine-derived alkaloids from the red sea sponge Suberea mollis. | 2011 | J. Nat. Prod. | pmid:21542602 |
Zhao DL et al. | Characterization of a cryptic plasmid pSM429 and its application for heterologous expression in psychrophilic Pseudoalteromonas. | 2011 | Microb. Cell Fact. | pmid:21542941 |
Gannon M et al. | Clinical inquiries. Which oral antibiotics are best for acne? | 2011 | J Fam Pract | pmid:21544278 |
Chia HY et al. | Follicular spicules associated with Propionibacterium acnes in response to erythromycin. | 2011 | J. Dermatol. | pmid:21544949 |
Nguyen TT et al. | A food-grade system for inducible gene expression in Lactobacillus plantarum using an alanine racemase-encoding selection marker. | 2011 | J. Agric. Food Chem. | pmid:21504147 |
Tilmant K et al. | Comparison of a genomic and a multiplex cell imaging approach for the detection of phospholipidosis. | 2011 | Toxicol In Vitro | pmid:21515356 |
Ma X and Ma S | Significant breakthroughs in search for anti-infectious agents derived from erythromycin A. | 2011 | Curr. Med. Chem. | pmid:21517774 |
Wei Z et al. | [Treatment of low-dose erythromycin and sinus displacement on sinusitis in patients with nasopharyngeal carcinoma after radiotherapy]. | 2011 | Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi | pmid:22260078 |