erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Schalén L et al. | Acute laryngitis in adults: results of erythromycin treatment. | 1992 | Acta Otolaryngol Suppl | pmid:1632252 |
| Sundberg L et al. | Penetration of erythromycin through respiratory mucosa. A study using secretory otitis media as a model. | 1979 | Acta Otolaryngol Suppl | pmid:294806 |
| Trollfors B | Whooping cough--aspects of pathogenesis and treatment. | 1984 | Acta Otolaryngol Suppl | pmid:6093425 |
| Sundberg L et al. | Tissue penetration of erythromycin in Waldeyer's ring and bacteriology of secretory otitis media. | 1981 | Acta Otolaryngol Suppl | pmid:6285661 |
| Sundberg L | Antibiotic treatment of secretory otitis media. | 1984 | Acta Otolaryngol Suppl | pmid:6388231 |
| Sandström I | Neonatal conjunctivitis caused by Chlamydia trachomatis. | 1984 | Acta Otolaryngol Suppl | pmid:6388234 |
| Forsgren A and Walder M | Activity of common antibiotics against Branhamella catarrhalis, Haemophilus influenzae, pneumococci, group A streptococci and Staphylococcus aureus in 1983. | 1984 | Acta Otolaryngol Suppl | pmid:6437134 |
| Erythromycin, past, present and future. Symposium, Vettere Konferense- og Studiesenter, Asker , Norway, September 16, 1983. | 1984 | Acta Otolaryngol Suppl | pmid:6594027 | |
| Frøland SS | Legionella pneumonia--a neglected diagnosis? | 1984 | Acta Otolaryngol Suppl | pmid:6594028 |
| Jerve F | Treatment of genital tract infections due to Chlamydia trachomatis. | 1984 | Acta Otolaryngol Suppl | pmid:6594029 |
| Hashiba M and Baba S | Efficacy of long-term administration of clarithromycin in the treatment of intractable chronic sinusitis. | 1996 | Acta Otolaryngol Suppl | pmid:8908275 |
| Palva T et al. | Effect of erythromycin on adenoid bacteria. | 1986 Mar-Apr | Acta Otolaryngol. | pmid:3486544 |
| Axelsson A et al. | Treatment of acute maxillary sinusitis. IV. Ampicillin, cephradine and erythromycinestolate with and without irrigation. | 1975 May-Jun | Acta Otolaryngol. | pmid:1155056 |
| Björkwall T | Local treatment with antibiotics in cases of maxillary sinusitis. | 1966 | Acta Otolaryngol. | pmid:5992657 |
| Liu J et al. | Inhibitory effect of erythromycin on ion transport by stria vascularis and vestibular dark cells. | 1996 | Acta Otolaryngol. | pmid:8831844 |
| Freijd A and Rynnel-Dagöö B | Isolation of nasopharyngeal beta-lactamase producing Haemophilus influenzae, in relation to antibiotic treatment of acute otitis media in infants. | 1983 Mar-Apr | Acta Otolaryngol. | pmid:6404124 |
| Sundberg L et al. | The effect of erythromycin on the nasopharyngeal pathogens in children with secretory otitis media. | 1984 Mar-Apr | Acta Otolaryngol. | pmid:6609521 |
| Cervin A | The anti-inflammatory effect of erythromycin and its derivatives, with special reference to nasal polyposis and chronic sinusitis. | 2001 | Acta Otolaryngol. | pmid:11270500 |
| Hassid S | [Otitis media caused by Mycoplasma pneumoniae]. | 1985 | Acta Otorhinolaryngol Belg | pmid:3938913 |
| Melon J and Reginster M | [Passage into normal salivary, lacrimal and nasal secretions of ampicillin and erythromycin administered intramuscularly]. | 1976 | Acta Otorhinolaryngol Belg | pmid:1028340 |