erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Bachmann K et al. | A study of the interaction between dirithromycin and astemizole in healthy adults. | 1997 Feb-Mar | Am J Ther | pmid:10423595 |
Cvetanovic I et al. | The differential antibacterial and gastrointestinal effects of erythromycin and its chiral isolates. | 2006 Jan-Feb | Am J Ther | pmid:16428922 |
Miller SD | Madura foot: treatment of Nocardia nova infection with antibiotics alone. | 2001 | Am J. Orthop. | pmid:11411876 |
Ciummo PE and Katz NL | Interactions and drug-metabolizing enzymes. | 1995 | Am Pharm | pmid:7484817 |
Mullan PA | Rand Corporation issues PPI study findings. | 1981 | Am Pharm | pmid:7340488 |
PARROTT FD et al. | Staphylococcal bacteremia: report of a case successfully treated with erythromycin. | 1954 | Am Pract Dig Treat | pmid:13171526 |
FLIPPIN HF and FOLTZ EL | The newer antimicrobial agents. | 1953 | Am Pract Dig Treat | pmid:13080581 |
PELNER L and PUDERBACH W | Pseudomembranous staphylococcal enterocolitis: recovery in two patients treated with erythromycin; some notes on antibiotic resistance. | 1956 | Am Pract Dig Treat | pmid:13362857 |
Baird RM | Postoperative infections from bacteroides. | 1973 | Am Surg | pmid:4722418 |
Stellato TA et al. | Antibiotics in elective colon surgery. A randomized trial of oral, systemic, and oral/systemic antibiotics for prophylaxis. | 1990 | Am Surg | pmid:2194417 |
Hoffman E | Prophylactic antibiotic usage in clean surgical procedures. | 1984 | Am Surg | pmid:6703529 |
Dunlop EM | Penicillin and the control of syphilis. | 1974 | Am. Heart J. | pmid:4606895 |
Clark H | An evaluation of antibiotic prophylaxis in cardiac catheterization. | 1969 | Am. Heart J. | pmid:5192402 |
Chennareddy SB et al. | Erythromycin-induced polymorphous ventricular tachycardia with normal QT interval. | 1996 | Am. Heart J. | pmid:8800045 |
Orban Z et al. | Erythromycin-induced cardiac toxicity. | 1995 | Am. J. Cardiol. | pmid:7536388 |
Guelon D et al. | QT prolongation and recurrent "torsades de pointes" during erythromycin lactobionate infusion. | 1986 | Am. J. Cardiol. | pmid:3751946 |
Devereux RB et al. | Cost-effectiveness of infective endocarditis prophylaxis for mitral valve prolapse with or without a mitral regurgitant murmur. | 1994 | Am. J. Cardiol. | pmid:7977041 |
Freedman RA et al. | Effect of erythromycin on ventricular arrhythmias and ventricular repolarization in idiopathic long QT syndrome. | 1987 | Am. J. Cardiol. | pmid:3812231 |
McComb JM et al. | Recurrent ventricular tachycardia associated with QT prolongation after mitral valve replacement and its association with intravenous administration of erythromycin. | 1984 | Am. J. Cardiol. | pmid:6486045 |
Alkhawajah AM | Studies on the antimicrobial activity of juglans regia. | 1997 | Am. J. Chin. Med. | pmid:9288364 |