erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Kligman AM | The treatment of acne. Part III: antibacterials. | 1995 | Cutis | pmid:8654122 |
Packman AM et al. | Treatment of acne vulgaris: combination of 3% erythromycin and 5% benzoyl peroxide in a gel compared to clindamycin phosphate lotion. | 1996 | Int. J. Dermatol. | pmid:8655242 |
King DE et al. | Effectiveness of erythromycin in the treatment of acute bronchitis. | 1996 | J Fam Pract | pmid:8656171 |
Aleksandrova AE and Vinogradova TI | [Immunotropic activity of antimicrobial agents used in tuberculosis]. | 1996 | Probl Tuberk | pmid:8657696 |
Johnson AP et al. | Prevalence of antibiotic resistance and serotypes in pneumococci in England and Wales: results of observational surveys in 1990 and 1995. | 1996 | BMJ | pmid:8664623 |
Lode H et al. | Treatment of community-acquired pneumonia: a randomized comparison of sparfloxacin, amoxycillin-clavulanic acid and erythromycin. | 1995 | Eur. Respir. J. | pmid:8666093 |
McMeekin TO and Moschella SL | Iatrogenic complications of dermatologic therapy. Primum non nocere. | 1979 | Med. Clin. North Am. | pmid:86664 |
Nikulin KG | [Treatment of acute pneumonia at different stages of the disease]. | 1977 | Ter. Arkh. | pmid:867244 |
Surrenti E et al. | Antral axial forces postprandially and after erythromycin in organic and functional dysmotilities. | 1996 | Dig. Dis. Sci. | pmid:8674390 |
Zhou D and Apicella MA | Plasmids with erythromycin resistance and catechol 2,3-dioxygenase- or beta-galactosidase-encoding gene cassettes for use in Neisseria spp. | 1996 | Gene | pmid:8675023 |
Rowbury RJ et al. | Sensitization to acid induced by sodium ions in Escherichia coli: dependence of (p)ppGpp and cAMP and suppression of the relA-associated defect by mutations in envZ. | 1996 | Microbios | pmid:8676748 |
Coulter WA et al. | Dental anxiety and the absorption of orally administered erythromycin stearate. | 1995 | Oral Surg Oral Med Oral Pathol Oral Radiol Endod | pmid:8680971 |
Sturm A et al. | [Treatment of radiotherapy-induced gastroparesis with erythromycin]. | 1996 | Dtsch. Med. Wochenschr. | pmid:8681733 |
Backström M and Kuusela AL | [Unilateral pulmonary edema in an infant]. | 1995 | Duodecim | pmid:8681845 |
Davies JS and Penfold JB | Campylobacter urinary infection. | 1979 | Lancet | pmid:86820 |
Griesgraber G et al. | 3-Keto-11,12-carbazate derivatives of 6-O-methylerythromycin A synthesis and in vitro activity. | 1996 | J. Antibiot. | pmid:8682724 |
Faghih R et al. | Synthesis and antibacterial activity of 6-deoxysporeamicin A. | 1996 | J. Antibiot. | pmid:8682729 |
Samulak KM et al. | Randomized, double blind comparison of brand and generic antibiotic suspensions: I. A study of taste in adults. | 1996 | Pediatr. Infect. Dis. J. | pmid:8684870 |
El-Chaar GM et al. | Randomized, double blind comparison of brand and generic antibiotic suspensions: II. A study of taste and compliance in children. | 1996 | Pediatr. Infect. Dis. J. | pmid:8684871 |
Edelman K et al. | Detection of Bordetella pertussis by polymerase chain reaction and culture in the nasopharynx of erythromycin-treated infants with pertussis. | 1996 | Pediatr. Infect. Dis. J. | pmid:8684877 |
Burgin S and Spencer DC | Bacillary angiomatosis--another South African case. | 1996 | S. Afr. Med. J. | pmid:8685799 |
Matschiner S et al. | Optimization of topical erythromycin formulations by ion pairing. | 1995 | Skin Pharmacol. | pmid:8688198 |
Bailey DG et al. | Erythromycin-felodipine interaction: magnitude, mechanism, and comparison with grapefruit juice. | 1996 | Clin. Pharmacol. Ther. | pmid:8689808 |
Sanchez MA and Rorat E | Fine needle aspiration diagnosis of intramuscular bacillary angiomatosis. A case report. | 1996 Jul-Aug | Acta Cytol. | pmid:8693899 |
Hall JE and Harmer M | Erythromycin as a prokinetic agent in children. | 1996 | Anaesthesia | pmid:8694177 |
Horowitz MS and Smith LG | Vegetative bacterial endocarditis on the prolapsing mitral valve. Echocardiographic evaluation. | 1977 | Arch. Intern. Med. | pmid:869651 |
Koizumi A et al. | [Effect of prolonged administration of erythromycin on the drug sensitivity and the biological properties of Streptococcus pneumoniae]. | 1996 | Kansenshogaku Zasshi | pmid:8699091 |
Cadisch R et al. | [Exacerbation of pseudoparalytic myasthenia gravis following azithromycin (Zithromax)]. | 1996 | Schweiz Med Wochenschr | pmid:8701248 |
Wasteson Y et al. | Characterization of tetracycline and erythromycin resistance in Actinobacillus pleuropneumoniae. | 1996 | Vet. Microbiol. | pmid:8701576 |
McBride MJ and Baker SA | Development of techniques to genetically manipulate members of the genera Cytophaga, Flavobacterium, Flexibacter, and Sporocytophaga. | 1996 | Appl. Environ. Microbiol. | pmid:8702294 |
RamÃrez RamÃrez CR et al. | Bacillary angiomatosis: microbiology, histopathology, clinical presentation, diagnosis and management. | 1995 Jul-Sep | Bol Asoc Med P R | pmid:8703269 |
Higgins SP | Chlamydial infection in women. | 1996 | Br J Gen Pract | pmid:8703535 |
Zanetti S et al. | In-vitro activity of 3-azinomethyl-rifamycin (SPA-S-565) against Chlamydia trachomatis. | 1996 | J. Antimicrob. Chemother. | pmid:8707747 |
Paz HL et al. | Motility agents for the placement of weighted and unweighted feeding tubes in critically ill patients. | 1996 | Intensive Care Med | pmid:8708166 |
Arranz-Caso JA et al. | Prolonged colonic pseudo-obstruction (Ogilvie syndrome) in an older woman resolved with conservative treatment. | 1996 | J Am Geriatr Soc | pmid:8708296 |
Nichterlein T et al. | RP 59500, a streptogramin derivative, is effective in murine listeriosis. | 1996 | J Chemother | pmid:8708741 |
Vanderhoof JA et al. | Treatment of cyclic vomiting in childhood with erythromycin. | 1995 | J. Pediatr. Gastroenterol. Nutr. | pmid:8708873 |
Chattopadhyay S et al. | Reactivation of denatured proteins by 23S ribosomal RNA: role of domain V. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8710862 |
Tateishi T et al. | Identification of human liver cytochrome P-450 3A4 as the enzyme responsible for fentanyl and sufentanil N-dealkylation. | 1996 | Anesth. Analg. | pmid:8712396 |
Orden B et al. | [Antibiotic resistance to erythromycin, clindamycin and tetracycline of 573 strains of Streptococcus pyogenes (1992-1994)]. | 1996 | Enferm. Infecc. Microbiol. Clin. | pmid:8714154 |
Mortensen JE and McDowell T | Streptococcus pyogenes: resistant, tolerant, neither or both? | 1995 | Adv. Exp. Med. Biol. | pmid:8718606 |
Ferraro AL et al. | The antimicrobial susceptibility of Streptococcus pyogenes isolates from the Philadelphia area. | 1995 | Adv. Exp. Med. Biol. | pmid:8718607 |
Altrichter T and Heizmann WR | [Gardnerella vaginalis: transport, microscopy, testing resistance]. | 1994 | Geburtshilfe Frauenheilkd | pmid:8719002 |
Zimmermann T et al. | Influence of the antibiotics erythromycin and azithromycin on the pharmacokinetics and pharmacodynamics of midazolam. | 1996 | Arzneimittelforschung | pmid:8720318 |
Khan MA et al. | A reverse transcriptase-PCR based assay for in-vitro antibiotic susceptibility testing of Chlamydia pneumoniae. | 1996 | J. Antimicrob. Chemother. | pmid:8722533 |
Hall G et al. | Elimination of bacteraemia after dental extraction: comparison of erythromycin and clindamycin for prophylaxis of infective endocarditis. | 1996 | J. Antimicrob. Chemother. | pmid:8722544 |
van Hoogdalem EJ et al. | Evaluation of the effect of zinc acetate on the stratum corneum penetration kinetics of erythromycin in healthy male volunteers. | 1996 | Skin Pharmacol. | pmid:8722604 |
Champney WS and Burdine R | 50S ribosomal subunit synthesis and translation are equivalent targets for erythromycin inhibition in Staphylococcus aureus. | 1996 | Antimicrob. Agents Chemother. | pmid:8723490 |
Fujii T et al. | Inhibitory effect of erythromycin on interleukin 8 production by 1 alpha,25-dihydroxyvitamin D3-stimulated THP-1 cells. | 1996 | Antimicrob. Agents Chemother. | pmid:8726037 |
Brouqui P et al. | Eucaryotic cells protect Borrelia burgdorferi from the action of penicillin and ceftriaxone but not from the action of doxycycline and erythromycin. | 1996 | Antimicrob. Agents Chemother. | pmid:8726038 |