erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Lopes Cardoso FL et al. | Rhodococcus equi mastoiditis in a patient with AIDS. | 1996 | Clin. Infect. Dis. | pmid:8729214 |
Moore JE et al. | Erythromycin-resistant thermophilic Campylobacter species isolated from pigs. | 1996 | Vet. Rec. | pmid:8730692 |
Box SA and Lee MR | A systemic reaction following exposure to a pyrethroid insecticide. | 1996 | Hum Exp Toxicol | pmid:8735461 |
Shinkai I and Ohta Y | New drugs--reports of new drugs recently approved by the FDA. Dirithromycin. | 1996 | Bioorg. Med. Chem. | pmid:8735838 |
Gómez-Lechón MJ et al. | Evidence of antibodies to erythromycin in serum of a patient following an episode of acute drug-induced hepatitis. | 1996 | Clin. Exp. Allergy | pmid:8735873 |
Aubier M et al. | Sparfloxacin for the treatment of community-acquired pneumonia: a pooled data analysis of two studies. | 1996 | J. Antimicrob. Chemother. | pmid:8737127 |
Ripoll L et al. | Interaction of macrolides with alpha dornase during DNA hydrolysis. | 1996 | J. Antimicrob. Chemother. | pmid:8737148 |
Hoppe JE | Update of epidemiology, diagnosis, and treatment of pertussis. | 1996 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:8740851 |
Ohba M et al. | Effect of clarithromycin on the bioavailability of cyclosporin in rats. | 1996 | Biol. Pharm. Bull. | pmid:8741585 |
Kozak PP et al. | Administration of erythromycin to patients on theophylline. | 1977 | J. Allergy Clin. Immunol. | pmid:874213 |
Abeck D and Ballard RC | Chancroid. | 1996 | Curr. Probl. Dermatol. | pmid:8743258 |
Eady EA et al. | The effects of acne treatment with a combination of benzoyl peroxide and erythromycin on skin carriage of erythromycin-resistant propionibacteria. | 1996 | Br. J. Dermatol. | pmid:8745894 |
Tenover FC et al. | Evaluation of commercial methods for determining antimicrobial susceptibility of Streptococcus pneumoniae. | 1996 | J. Clin. Microbiol. | pmid:8748262 |
Seppälä H et al. | Outpatient use of erythromycin: link to increased erythromycin resistance in group A streptococci. | 1995 | Clin. Infect. Dis. | pmid:8749619 |
Piérard-Franchimont C et al. | A double-blind controlled evaluation of the sebosuppressive activity of topical erythromycin-zinc complex. | 1995 | Eur. J. Clin. Pharmacol. | pmid:8751022 |
Fontán PA et al. | Haemophilus influenzae type b exoproducts induce chemotaxis and macrolide antibiotic release by human polymorphonuclear leukocytes. | 1996 Jan-Feb | Chemotherapy | pmid:8751269 |
Sakuragi T | [Study on levels of chemotherapeutics in prostatic tissue and prostatic fluid or seminal plasma. 2. Concentrations of erythromycin (EM), aminobenzylpenicillin (ABPC)-methylchlorophenylisoxazolylpenicillin (MCIPC) and sulfamethoxazole-trimethoprim (SMX-TMP) (AUTHOR'S TRANSL)]. | 1979 | Nippon Hinyokika Gakkai Zasshi | pmid:87532 |
Bianchi A et al. | [Comparative study of minimal inhibiting concentrations of doxycycline, ofloxacin and erythromycin against 18 recent isolates from Chlamydia trachomatis (1994-1995)]. | 1996 | Pathol. Biol. | pmid:8758473 |
Del Giudice L and Brunner A | Chromosomal and extrachromosomal inheritance of erythromycin-resistance in the "petite-negative" yeast Kluyveromyces lactis. | 1977 | Mol. Gen. Genet. | pmid:876030 |
Stuart JM et al. | Antibiotic prescribing during an outbreak of meningococcal disease. | 1996 | Epidemiol. Infect. | pmid:8760956 |
Alcalde AI et al. | Study of the action of intramuscularly administered erythromycin on the L-threonine transport and the digestive enzymatic activity in rabbit jejunum. | 1996 | Life Sci. | pmid:8761316 |
Fu D et al. | [Contractile effect of erythromycin on the gallbladder]. | 1995 | Zhonghua Wai Ke Za Zhi | pmid:8762558 |
Rémy AJ et al. | [Acute hepatitis caused by Campylobacter fetus]. | 1996 | Gastroenterol. Clin. Biol. | pmid:8763076 |
Chen CK et al. | Factors involved in the transformation of previously non-transformable Clostridium perfringens type B. | 1996 | FEMS Microbiol. Lett. | pmid:8764481 |
Ko YY et al. | Recurrent infection of Legionella pneumonia: a case report. | 1996 | Zhonghua Yi Xue Za Zhi (Taipei) | pmid:8768386 |
Welling PG | How food and fluid affect drug absorption: results of initial studies. | 1977 | Postgrad Med | pmid:876907 |
Isenberg SJ et al. | The influence of perinatal infective factors on ophthalmia neonatorum. | 1996 May-Jun | J Pediatr Ophthalmol Strabismus | pmid:8771523 |
Granberry MC and Gardner SF | Erythromycin monotherapy associated with torsade de pointes. | 1996 | Ann Pharmacother | pmid:8773169 |
Hasfurther DL and Bailey PL | Failure of neuromuscular blockade reversal after rocuronium in a patient who received oral neomycin. | 1996 | Can J Anaesth | pmid:8773869 |
Mota CR et al. | Severe carbamazepine toxicity induced by concurrent erythromycin therapy. | 1996 | Eur. J. Pediatr. | pmid:8777933 |
Parkman HP et al. | Erythromycin inhibits rabbit pyloric smooth muscle through neuronal motilin receptors. | 1996 | Gastroenterology | pmid:8780573 |
Bussières J et al. | Optional elements in the chloroplast DNAs of chlamydomonas eugametos and C. moewusii: unidirectional gene conversion and co-conversion of adjacent markers in high-viability crossses. | 1996 | Curr. Genet. | pmid:8781180 |
Heath CH et al. | Delay in appropriate therapy of Legionella pneumonia associated with increased mortality. | 1996 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:8781878 |
Durak H et al. | Lung clearance of aerosolized 99mTc erythromycin lactobionate in rabbits. | 1996 | Nucl. Med. Biol. | pmid:8782239 |
Welsh L et al. | In vitro activities of azithromycin, clarithromycin, erythromycin, and tetracycline against 13 strains of Chlamydia pneumoniae. | 1996 | Antimicrob. Agents Chemother. | pmid:8787907 |
Mehaffey PC et al. | Evaluation of in vitro spectra of activity of azithromycin, clarithromycin, and erythromycin tested against strains of Neisseria gonorrhoeae by reference agar dilution, disk diffusion, and Etest methods. | 1996 | J. Clin. Microbiol. | pmid:8789046 |
Bohlen DM et al. | Lack of effect of ivermectin on antipyrine and erythromycin disposition in calves. | 1995 | J. Vet. Pharmacol. Ther. | pmid:8789704 |
Inatomi N et al. | Vagus-dependent and vagus-independent mechanisms of action of the erythromycin derivative EM574 and motilin in dogs. | 1996 | Jpn. J. Pharmacol. | pmid:8791169 |
Laine L et al. | Prospective evaluation of the macrolide antibiotic dirithromycin for the treatment of Helicobacter pylori. | 1996 | Aliment. Pharmacol. Ther. | pmid:8791949 |
Wehrmann T et al. | Effect of erythromycin on human biliary motility. | 1996 | Aliment. Pharmacol. Ther. | pmid:8791972 |
Hsieh MH et al. | Drug-induced torsades de pointes in one patient with congenital long QT syndrome. | 1996 | Int. J. Cardiol. | pmid:8792191 |
Griffith RS et al. | Synergistic action of erythromycin and cefamandole against Bacteroides fragilis subsp. fragilis. | 1977 | Antimicrob. Agents Chemother. | pmid:879736 |
van Embden JD et al. | Drug resistance in group D streptococci of clinical and nonclinical origin: prevalence, transferability, and plasmid properties. | 1977 | Antimicrob. Agents Chemother. | pmid:879758 |
Franko JP | Erythromycin for treatment of acute bronchitis. | 1996 | J Fam Pract | pmid:8797744 |
Chennareddy SB et al. | Erythromycin-induced polymorphous ventricular tachycardia with normal QT interval. | 1996 | Am. Heart J. | pmid:8800045 |
Eden CG et al. | Human immunodeficiency virus-related bacillary angiomatosis of the penis. | 1996 | Br J Urol | pmid:8800916 |
Son DS et al. | Contribution of alpha 1-acid glycoprotein to plasma protein binding of some basic antimicrobials in pigs. | 1996 | J. Vet. Pharmacol. Ther. | pmid:8803875 |
Traub WH and Leonhard B | Antibiotic susceptibility of clinical isolates of Streptococcus pneumoniae. | 1996 Jul-Aug | Chemotherapy | pmid:8804790 |
Stevens DL | Invasive group A streptococcal disease. | 1996 | Infect Agents Dis | pmid:8805078 |
Recommended treatment of syphilis and gonorrhea. Advisory Committee on venereal Disease Control, Health and Welfare Canada. | 1977 | Can Med Assoc J | pmid:880529 |