erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
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Authors | Title | Published | Journal | PubMed Link |
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Vermot D et al. | Efficacy of clarithromycin versus that of clindamycin for single-dose prophylaxis of experimental streptococcal endocarditis. | 1996 | Antimicrob. Agents Chemother. | pmid:8851620 |
Chang AD et al. | Bacillary angiomatosis associated with extensive esophageal polyposis: a new mucocutaneous manifestation of acquired immunodeficiency disease (AIDS). | 1996 | Am. J. Gastroenterol. | pmid:8855753 |
Raab W | [Acute side effects of erythromycin, lincomycin and clindamycin]. | 1977 | Int J Clin Pharmacol Biopharm | pmid:885668 |
Hofstetter A | [Mycoplasma infections of urogenital tract]. | 1977 | Hautarzt | pmid:885718 |
Watkins PB | Erythromycin breath test and clinical transplantation. | 1996 | Ther Drug Monit | pmid:8857552 |
Vanakoski J et al. | Grapefruit juice does not enhance the effects of midazolam and triazolam in man. | 1996 | Eur. J. Clin. Pharmacol. | pmid:8858279 |
Lacey RW | Lack of evidence for mutation to erythromycin resistance in clinical strains of Staphylococcus aureus. | 1977 | J. Clin. Pathol. | pmid:886013 |
Burnens AP et al. | Sequential development of resistance to fluoroquinolones and erythromycin in an isolate of Campylobacter jejuni. | 1996 | Zentralbl. Bakteriol. | pmid:8861869 |
Xu G et al. | Effect of macrolide antibiotics on macrophage functions. | 1996 | Microbiol. Immunol. | pmid:8865152 |
Ogawa T et al. | [Effect of erythromycin on early delayed gastric emptying after pylorus preserving pancreatoduodenectomy--case report]. | 1996 | Nihon Shokakibyo Gakkai Zasshi | pmid:8865759 |
Toyota K et al. | A study of pyloric function after pylorus-preserving pancreatoduodenectomy in the canine model. | 1995 | J Smooth Muscle Res | pmid:8867940 |
Shiba Y et al. | [Mechanism of increased gastric motility effect of EM523]. | 1995 | J Smooth Muscle Res | pmid:8867984 |
Sato M et al. | [Erythromycin derivative EM574 with motilin agonistic effect on human gastric antrum]. | 1995 | J Smooth Muscle Res | pmid:8867985 |
Ridgway GL and Oriel JD | Treatment of neonatal inclusion blennorrhea. | 1977 | N. Engl. J. Med. | pmid:887138 |
Jones DR et al. | Determination of cytochrome P450 3A4/5 activity in vivo with dextromethorphan N-demethylation. | 1996 | Clin. Pharmacol. Ther. | pmid:8873685 |
Gómez J et al. | Prospective study of epidemiology and prognostic factors in community-acquired pneumonia. | 1996 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:8874072 |
Kürekçi AE et al. | The frequency of resistance to erythromycin in group A streptococci in Ankara. | 1996 | Eur. J. Pediatr. | pmid:8874111 |
Uwaydah M et al. | Antimicrobial resistance of clinical isolates of Streptococcus pneumoniae in Lebanon. | 1996 | J. Antimicrob. Chemother. | pmid:8877543 |
Amin AS and Issa YM | Selective spectrophotometric method for the determination of erythromycin and its esters in pharmaceutical formulations using gentiana violet. | 1996 | J Pharm Biomed Anal | pmid:8877871 |
Pankuch GA et al. | MIC and time-kill study of antipneumococcal activities of RPR 106972 (a new oral streptogramin), RP 59500 (quinupristin-dalfopristin), pyostacine (RP 7293), penicillin G, cefotaxime, erythromycin, and clarithromycin against 10 penicillin-susceptible and -resistant pneumococci. | 1996 | Antimicrob. Agents Chemother. | pmid:8878583 |
Alcaide F et al. | In vitro activities of eight macrolide antibiotics and RP-59500 (quinupristin-dalfopristin) against viridans group streptococci isolated from blood of neutropenic cancer patients. | 1996 | Antimicrob. Agents Chemother. | pmid:8878591 |
Valsecchi R et al. | Contact allergy to erythromycin. | 1996 | Contact Derm. | pmid:8879932 |
Davies P et al. | Erythromycin resistance of Campylobacter isolates from pigs. | 1996 | Vet. Rec. | pmid:8883355 |
Viluksela M et al. | Cytotoxicity of macrolide antibiotics in a cultured human liver cell line. | 1996 | J. Antimicrob. Chemother. | pmid:8889721 |
Biedenbach D et al. | Comparative in-vitro activity of quinupristin/dalfopristin (RP 59500) tested against penicillin-and macrolide-resistant pneumococci by the Etest. | 1996 | J. Antimicrob. Chemother. | pmid:8889731 |
Benson JM et al. | Tonsillar tissue penetration of dirithromycin after multiple doses. | 1996 | J Clin Pharmacol | pmid:8889904 |
Tateda K et al. | Direct evidence for antipseudomonal activity of macrolides: exposure-dependent bactericidal activity and inhibition of protein synthesis by erythromycin, clarithromycin, and azithromycin. | 1996 | Antimicrob. Agents Chemother. | pmid:8891128 |
Hunt Gerardo S et al. | Comparison of Etest to broth microdilution method for testing Streptococcus pneumoniae susceptibility to levofloxacin and three macrolides. | 1996 | Antimicrob. Agents Chemother. | pmid:8891154 |
Wintermeyer SM et al. | Dirithromycin: a new macrolide. | 1996 | Ann Pharmacother | pmid:8893122 |
Clarke JS et al. | Preoperative oral antibiotics reduce septic complications of colon operations: results of prospective, randomized, double-blind clinical study. | 1977 | Ann. Surg. | pmid:889372 |
Shinagawa S et al. | Exacerbation of tracheobronchitis due to nontoxigenic Corynebacterium diphtheriae. | 1996 | Intern. Med. | pmid:8894741 |
Ross JD et al. | Efficacy of anti-chlamydial therapy with oxytetracycline and erythromycin. | 1996 Aug-Sep | Int J STD AIDS | pmid:8894832 |
Matschiner S et al. | Influence of ion pairing on ex vivo penetration of erythromycin into sebaceous follicles. | 1996 | Skin Pharmacol. | pmid:8896118 |
Scott DW et al. | Further studies on the efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs. | 1996 | Can. Vet. J. | pmid:8896878 |
Nay TS | Extra-pulmonary Rhodococcus equi in a thoroughbred foal. | 1996 | Can. Vet. J. | pmid:8896881 |
Wadowsky RM et al. | Multiplex PCR-based assay for detection of Bordetella pertussis in nasopharyngeal swab specimens. | 1996 | J. Clin. Microbiol. | pmid:8897157 |
Jorgensen JH et al. | Development of interpretive criteria and quality control limits for macrolide and clindamycin susceptibility testing of Streptococcus pneumoniae. | 1996 | J. Clin. Microbiol. | pmid:8897164 |
Jayaraman SC et al. | Topical delivery of erythromycin from various formulations: an in vivo hairless mouse study. | 1996 | J Pharm Sci | pmid:8897275 |
Yau TH and Butrus SI | Presumed bilateral herpes zoster ophthalmicus in an AIDS patient: a case report. | 1996 | Cornea | pmid:8899277 |
Okano H et al. | EM523L, a nonpeptide motilin agonist, stimulates gastric emptying and pancreatic polypeptide secretion. | 1996 | Peptides | pmid:8899806 |
Guerrero-Lindner E et al. | Effect of motilin on gastrointestinal myoelectric activity in conscious rabbits. | 1996 | Peptides | pmid:8899807 |
Flurer CL | Analysis of macrolide antibiotics by capillary electrophoresis. | 1996 | Electrophoresis | pmid:8900943 |
Segreti J et al. | In vitro activity of macrolides against intracellular Legionella pneumophila. | 1996 | Diagn. Microbiol. Infect. Dis. | pmid:8902407 |
Wheeley MS | Erythromycin in renal failure. | 1977 | Br Med J | pmid:890394 |
Kimani J et al. | Low dose erythromycin regimen for the treatment of chancroid. | 1995 | East Afr Med J | pmid:8904044 |
Ohtomo T et al. | Effect of sub-inhibitory concentrations of clarithromycin and erythromycin on the production of Staphylococcus aureus capsules. | 1995 | J Chemother | pmid:8904089 |
Perez-Ramos S et al. | Incidence of erythromycin resistance and penicillin resistance in clinical isolates of Streptococcus pneumoniae from a Spanish university hospital. | 1995 | J Chemother | pmid:8904113 |
Mosca A et al. | Evaluation of the efficacy of josamycin in the treatment of impetigo in children and its in vitro activity on erythromycin resistant Staphylococcus aureus strains. | 1995 | J Chemother | pmid:8904141 |
Yasui N | [The relationship between single-oral dose kinetics of alprazolam and cytochrome P4503A and cytochrome P4502C19]. | 1996 | Nihon Shinkei Seishin Yakurigaku Zasshi | pmid:8905799 |
Hashiba M and Baba S | Efficacy of long-term administration of clarithromycin in the treatment of intractable chronic sinusitis. | 1996 | Acta Otolaryngol Suppl | pmid:8908275 |