erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Liver Cirrhosis, Biliary D008105 12 associated lipids
Liver Diseases D008107 31 associated lipids
Long QT Syndrome D008133 10 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lupus Erythematosus, Cutaneous D008178 2 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lyme Disease D008193 5 associated lipids
Lymphadenitis D008199 8 associated lipids
Lymphangitis D008205 4 associated lipids
Lymphogranuloma Venereum D008219 4 associated lipids
Mycetoma D008271 4 associated lipids
Marfan Syndrome D008382 2 associated lipids
Mastoiditis D008417 2 associated lipids
Maxillofacial Injuries D008446 1 associated lipids
Megacolon D008531 1 associated lipids
Meningitis, Haemophilus D008583 3 associated lipids
Meningitis, Listeria D008584 1 associated lipids
Microphthalmos D008850 1 associated lipids
Stomatognathic Diseases D009057 1 associated lipids
Multiple Myeloma D009101 13 associated lipids
Myasthenia Gravis D009157 5 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Myiasis D009198 1 associated lipids
Nasal Polyps D009298 26 associated lipids
Nasopharyngeal Diseases D009302 2 associated lipids
Nasopharyngitis D009304 2 associated lipids
Nausea D009325 7 associated lipids
Nephritis, Interstitial D009395 10 associated lipids
Nervous System Diseases D009422 37 associated lipids
Hereditary Sensory and Autonomic Neuropathies D009477 1 associated lipids
Neutropenia D009503 15 associated lipids
Nocardia Infections D009617 6 associated lipids
Obesity D009765 29 associated lipids
Endophthalmitis D009877 12 associated lipids
Ophthalmia Neonatorum D009878 1 associated lipids
Psittacosis D009956 4 associated lipids
Orthomyxoviridae Infections D009976 3 associated lipids
Osteitis D010000 10 associated lipids
Osteolysis D010014 8 associated lipids
Osteomyelitis D010019 10 associated lipids
Otitis D010031 5 associated lipids
Otitis Externa D010032 8 associated lipids
Otitis Media D010033 12 associated lipids
Otitis Media with Effusion D010034 9 associated lipids
Otitis Media, Suppurative D010035 4 associated lipids
Otorhinolaryngologic Diseases D010038 3 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Vermot D et al. Efficacy of clarithromycin versus that of clindamycin for single-dose prophylaxis of experimental streptococcal endocarditis. 1996 Antimicrob. Agents Chemother. pmid:8851620
Chang AD et al. Bacillary angiomatosis associated with extensive esophageal polyposis: a new mucocutaneous manifestation of acquired immunodeficiency disease (AIDS). 1996 Am. J. Gastroenterol. pmid:8855753
Raab W [Acute side effects of erythromycin, lincomycin and clindamycin]. 1977 Int J Clin Pharmacol Biopharm pmid:885668
Hofstetter A [Mycoplasma infections of urogenital tract]. 1977 Hautarzt pmid:885718
Watkins PB Erythromycin breath test and clinical transplantation. 1996 Ther Drug Monit pmid:8857552
Vanakoski J et al. Grapefruit juice does not enhance the effects of midazolam and triazolam in man. 1996 Eur. J. Clin. Pharmacol. pmid:8858279
Lacey RW Lack of evidence for mutation to erythromycin resistance in clinical strains of Staphylococcus aureus. 1977 J. Clin. Pathol. pmid:886013
Burnens AP et al. Sequential development of resistance to fluoroquinolones and erythromycin in an isolate of Campylobacter jejuni. 1996 Zentralbl. Bakteriol. pmid:8861869
Xu G et al. Effect of macrolide antibiotics on macrophage functions. 1996 Microbiol. Immunol. pmid:8865152
Ogawa T et al. [Effect of erythromycin on early delayed gastric emptying after pylorus preserving pancreatoduodenectomy--case report]. 1996 Nihon Shokakibyo Gakkai Zasshi pmid:8865759
Toyota K et al. A study of pyloric function after pylorus-preserving pancreatoduodenectomy in the canine model. 1995 J Smooth Muscle Res pmid:8867940
Shiba Y et al. [Mechanism of increased gastric motility effect of EM523]. 1995 J Smooth Muscle Res pmid:8867984
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Ridgway GL and Oriel JD Treatment of neonatal inclusion blennorrhea. 1977 N. Engl. J. Med. pmid:887138
Jones DR et al. Determination of cytochrome P450 3A4/5 activity in vivo with dextromethorphan N-demethylation. 1996 Clin. Pharmacol. Ther. pmid:8873685
Gómez J et al. Prospective study of epidemiology and prognostic factors in community-acquired pneumonia. 1996 Eur. J. Clin. Microbiol. Infect. Dis. pmid:8874072
Kürekçi AE et al. The frequency of resistance to erythromycin in group A streptococci in Ankara. 1996 Eur. J. Pediatr. pmid:8874111
Uwaydah M et al. Antimicrobial resistance of clinical isolates of Streptococcus pneumoniae in Lebanon. 1996 J. Antimicrob. Chemother. pmid:8877543
Amin AS and Issa YM Selective spectrophotometric method for the determination of erythromycin and its esters in pharmaceutical formulations using gentiana violet. 1996 J Pharm Biomed Anal pmid:8877871
Pankuch GA et al. MIC and time-kill study of antipneumococcal activities of RPR 106972 (a new oral streptogramin), RP 59500 (quinupristin-dalfopristin), pyostacine (RP 7293), penicillin G, cefotaxime, erythromycin, and clarithromycin against 10 penicillin-susceptible and -resistant pneumococci. 1996 Antimicrob. Agents Chemother. pmid:8878583
Alcaide F et al. In vitro activities of eight macrolide antibiotics and RP-59500 (quinupristin-dalfopristin) against viridans group streptococci isolated from blood of neutropenic cancer patients. 1996 Antimicrob. Agents Chemother. pmid:8878591
Valsecchi R et al. Contact allergy to erythromycin. 1996 Contact Derm. pmid:8879932
Davies P et al. Erythromycin resistance of Campylobacter isolates from pigs. 1996 Vet. Rec. pmid:8883355
Viluksela M et al. Cytotoxicity of macrolide antibiotics in a cultured human liver cell line. 1996 J. Antimicrob. Chemother. pmid:8889721
Biedenbach D et al. Comparative in-vitro activity of quinupristin/dalfopristin (RP 59500) tested against penicillin-and macrolide-resistant pneumococci by the Etest. 1996 J. Antimicrob. Chemother. pmid:8889731
Benson JM et al. Tonsillar tissue penetration of dirithromycin after multiple doses. 1996 J Clin Pharmacol pmid:8889904
Tateda K et al. Direct evidence for antipseudomonal activity of macrolides: exposure-dependent bactericidal activity and inhibition of protein synthesis by erythromycin, clarithromycin, and azithromycin. 1996 Antimicrob. Agents Chemother. pmid:8891128
Hunt Gerardo S et al. Comparison of Etest to broth microdilution method for testing Streptococcus pneumoniae susceptibility to levofloxacin and three macrolides. 1996 Antimicrob. Agents Chemother. pmid:8891154
Wintermeyer SM et al. Dirithromycin: a new macrolide. 1996 Ann Pharmacother pmid:8893122
Clarke JS et al. Preoperative oral antibiotics reduce septic complications of colon operations: results of prospective, randomized, double-blind clinical study. 1977 Ann. Surg. pmid:889372
Shinagawa S et al. Exacerbation of tracheobronchitis due to nontoxigenic Corynebacterium diphtheriae. 1996 Intern. Med. pmid:8894741
Ross JD et al. Efficacy of anti-chlamydial therapy with oxytetracycline and erythromycin. 1996 Aug-Sep Int J STD AIDS pmid:8894832
Matschiner S et al. Influence of ion pairing on ex vivo penetration of erythromycin into sebaceous follicles. 1996 Skin Pharmacol. pmid:8896118
Scott DW et al. Further studies on the efficacy of tylosin tablets for the treatment of pyoderma due to Staphylococcus intermedius infection in dogs. 1996 Can. Vet. J. pmid:8896878
Nay TS Extra-pulmonary Rhodococcus equi in a thoroughbred foal. 1996 Can. Vet. J. pmid:8896881
Wadowsky RM et al. Multiplex PCR-based assay for detection of Bordetella pertussis in nasopharyngeal swab specimens. 1996 J. Clin. Microbiol. pmid:8897157
Jorgensen JH et al. Development of interpretive criteria and quality control limits for macrolide and clindamycin susceptibility testing of Streptococcus pneumoniae. 1996 J. Clin. Microbiol. pmid:8897164
Jayaraman SC et al. Topical delivery of erythromycin from various formulations: an in vivo hairless mouse study. 1996 J Pharm Sci pmid:8897275
Yau TH and Butrus SI Presumed bilateral herpes zoster ophthalmicus in an AIDS patient: a case report. 1996 Cornea pmid:8899277
Okano H et al. EM523L, a nonpeptide motilin agonist, stimulates gastric emptying and pancreatic polypeptide secretion. 1996 Peptides pmid:8899806
Guerrero-Lindner E et al. Effect of motilin on gastrointestinal myoelectric activity in conscious rabbits. 1996 Peptides pmid:8899807
Flurer CL Analysis of macrolide antibiotics by capillary electrophoresis. 1996 Electrophoresis pmid:8900943
Segreti J et al. In vitro activity of macrolides against intracellular Legionella pneumophila. 1996 Diagn. Microbiol. Infect. Dis. pmid:8902407
Wheeley MS Erythromycin in renal failure. 1977 Br Med J pmid:890394
Kimani J et al. Low dose erythromycin regimen for the treatment of chancroid. 1995 East Afr Med J pmid:8904044
Ohtomo T et al. Effect of sub-inhibitory concentrations of clarithromycin and erythromycin on the production of Staphylococcus aureus capsules. 1995 J Chemother pmid:8904089
Perez-Ramos S et al. Incidence of erythromycin resistance and penicillin resistance in clinical isolates of Streptococcus pneumoniae from a Spanish university hospital. 1995 J Chemother pmid:8904113
Mosca A et al. Evaluation of the efficacy of josamycin in the treatment of impetigo in children and its in vitro activity on erythromycin resistant Staphylococcus aureus strains. 1995 J Chemother pmid:8904141
Yasui N [The relationship between single-oral dose kinetics of alprazolam and cytochrome P4503A and cytochrome P4502C19]. 1996 Nihon Shinkei Seishin Yakurigaku Zasshi pmid:8905799
Hashiba M and Baba S Efficacy of long-term administration of clarithromycin in the treatment of intractable chronic sinusitis. 1996 Acta Otolaryngol Suppl pmid:8908275