erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with erythromycin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Trepanier LA and Miller JL | NADH-dependent reduction of sulphamethoxazole hydroxylamine in dog and human liver microsomes. | 2000 | Xenobiotica | pmid:11307968 |
Milne RW et al. | Hepatic disposition of fexofenadine: influence of the transport inhibitors erythromycin and dibromosulphothalein. | 2000 | Pharm. Res. | pmid:11303961 |
McGee L et al. | Serotype 19f multiresistant pneumococcal clone harboring two erythromycin resistance determinants (erm(B) and mef(A)) in South Africa. | 2001 | Antimicrob. Agents Chemother. | pmid:11302838 |
Ip M et al. | Macrolide resistance in Streptococcus pneumoniae in Hong Kong. | 2001 | Antimicrob. Agents Chemother. | pmid:11302833 |
Tsunoda SM et al. | Preliminary evaluation of progestins as inducers of cytochrome P450 3A4 activity in postmenopausal women. | 1998 | J Clin Pharmacol | pmid:11301566 |
Gunics G et al. | Enhanced antibacterial effect of erythromycin in the presence of 3,5-dibenzoyl-1,4-dihydropyridines. | 2001 Jan-Feb | Anticancer Res. | pmid:11299745 |
Craft JC | ABT-773 overview. | 2001 | Jpn J Antibiot | pmid:11296410 |
Kanazawa S et al. | The effects of grapefruit juice on the pharmacokinetics of erythromycin. | 2001 Jan-Feb | Eur. J. Clin. Pharmacol. | pmid:11294369 |
Kenyon SL et al. | Broad-spectrum antibiotics for spontaneous preterm labour: the ORACLE II randomised trial. ORACLE Collaborative Group. | 2001 | Lancet | pmid:11293641 |
Kenyon SL et al. | Broad-spectrum antibiotics for preterm, prelabour rupture of fetal membranes: the ORACLE I randomised trial. ORACLE Collaborative Group. | 2001 | Lancet | pmid:11293640 |
Queille-Roussel C et al. | Comparison of the cumulative irritation potential of adapalene gel and cream with that of erythromycin/tretinoin solution and gel and erythromycin/isotretinoin gel. | 2001 | Clin Ther | pmid:11293554 |
Ueno N et al. | Erythromycin administration before sleep is effective in decreasing fasting hyperglycemia in type 2 diabetic patients. | 2001 | Diabetes Care | pmid:11289494 |
Ge N et al. | Interferon-gamma activates outwardly rectifying chloride channels in the human bronchial epithelial cell line BEAS-2B. | 2001 | J. Med. Invest. | pmid:11286023 |
Bryskier A | Ketolides-telithromycin, an example of a new class of antibacterial agents. | 2000 | Clin. Microbiol. Infect. | pmid:11284926 |
Kanellopoulou M et al. | Isolation rate, T-serotyping and susceptibility to antibiotics of Group A Streptococcus from pediatric infections in Athens. | 2000 | Clin. Microbiol. Infect. | pmid:11284924 |
Osato MS et al. | Comparative efficacy of new investigational agents against Helicobacter pylori. | 2001 | Aliment. Pharmacol. Ther. | pmid:11284777 |
Montanari MP et al. | Differentiation of resistance phenotypes among erythromycin-resistant Pneumococci. | 2001 | J. Clin. Microbiol. | pmid:11283047 |
Vela AI et al. | Antimicrobial susceptibility of Listeria monocytogenes isolated from meningoencephalitis in sheep. | 2001 | Int. J. Antimicrob. Agents | pmid:11282267 |
Zouain MG and Araj GF | Antimicrobial resistance of Enterococci in Lebanon. | 2001 | Int. J. Antimicrob. Agents | pmid:11282266 |
Ioannidou S et al. | Antibiotic resistance rates and macrolide resistance phenotypes of viridans group streptococci from the oropharynx of healthy Greek children. | 2001 | Int. J. Antimicrob. Agents | pmid:11282264 |
Leyden JJ et al. | The efficacy and safety of a combination benzoyl peroxide/clindamycin topical gel compared with benzoyl peroxide alone and a benzoyl peroxide/erythromycin combination product. | 2001 Jan-Feb | J Cutan Med Surg | pmid:11281433 |
Papudesu B et al. | Invasive pneumococcal disease. | 2001 | Med Health R I | pmid:11280137 |
Steigbigel RT et al. | Antibiotic combinations in the treatment of experimental Staphylococcus aureus infection. | 1975 | J. Infect. Dis. | pmid:1127254 |
Avanzini C et al. | Streptococcus pyogenes collected in Torino (northwest Italy) between 1983 and 1998: survey of macrolide resistance and trend of genotype by RAPD. | 2000 | Microb. Drug Resist. | pmid:11272257 |
Ye H et al. | Antimycoplasmal activities of (S)-(-)-9-fluoro-2,3-dihydro-3-methyl-10 -[4-(2-pyridyl)-1-piperazinyl]-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine -6-carboxylic acid (YH-6) in comparison with other antibiotics in vitro. | 1999 | Zhongguo Yao Li Xue Bao | pmid:11270970 |
Champney WS and Tober CL | Structure-activity relationships for six ketolide antibiotics. | 2001 | Curr. Microbiol. | pmid:11270656 |
Cervin A | The anti-inflammatory effect of erythromycin and its derivatives, with special reference to nasal polyposis and chronic sinusitis. | 2001 | Acta Otolaryngol. | pmid:11270500 |
Schwartz JB | Race but not age affects erythromycin breath test results in older hypertensive men. | 2001 | J Clin Pharmacol | pmid:11269573 |
Sanz E et al. | Perception of teratogenic risk of common medicines. | 2001 | Eur. J. Obstet. Gynecol. Reprod. Biol. | pmid:11267734 |
Lunzer MR et al. | Jaundice due to erythromycin estolate. | 1975 | Gastroenterology | pmid:1126604 |
Oliva RodrÃguez-Pastor S et al. | [Erythromycin and hypertrophic stenosis of the pylorus]. | 2001 | An. Esp. Pediatr. | pmid:11262265 |
Yamano K et al. | Prediction of midazolam-CYP3A inhibitors interaction in the human liver from in vivo/in vitro absorption, distribution, and metabolism data. | 2001 | Drug Metab. Dispos. | pmid:11259329 |
Koeck JL et al. | [First confirmed case of laryngeal diphtheria in Djibouti]. | 2000 | Med Trop (Mars) | pmid:11258062 |
Perreten V et al. | Mdt(A), a new efflux protein conferring multiple antibiotic resistance in Lactococcus lactis and Escherichia coli. | 2001 | Antimicrob. Agents Chemother. | pmid:11257023 |
Nait-Kaci S et al. | [Sensitivity to beta lactams and macrolides of Streptococcus pyogenes isolated at the services from 1994 to 1998]. | 1998 | Arch Inst Pasteur Alger | pmid:11256303 |
Fernández-Roblas R et al. | The bactericidal activities of HMR 3004, HMR 3647 and erythromycin against gram-positive bacilli and development of resistance. | 1999 | J. Antimicrob. Chemother. | pmid:11252337 |
Bergogne-Bérézin E and Bryskier A | The suppository form of antibiotic administration: pharmacokinetics and clinical application. | 1999 | J. Antimicrob. Chemother. | pmid:11252322 |
Ross JI et al. | Phenotypic and genotypic characterization of antibiotic-resistant Propionibacterium acnes isolated from acne patients attending dermatology clinics in Europe, the U.S.A., Japan and Australia. | 2001 | Br. J. Dermatol. | pmid:11251569 |
Wagner CM | The care and management of pertussis in pediatric patients. | 2001 Mar-Apr | Air Med. J. | pmid:11250611 |
Hladka OA and Motyka OI | [Formation of erythromycin resistance in Corynebacterium diphtheriae induced by long-term effect of the antibiotic]. | 2000 Sep-Oct | Mikrobiol. Z. | pmid:11247343 |
Stamos G et al. | Emergence of group A beta-hemolytic streptococci resistant to erythromycin in Athens, Greece. | 2001 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:11245331 |
Uh Y et al. | Emerging erythromycin resistance among group B streptococci in Korea. | 2001 | Eur. J. Clin. Microbiol. Infect. Dis. | pmid:11245325 |
Nasser AA and Bizri AR | Chronic scalp wound infection due to Rhodococcus equi in an immunocompetent patient. | 2001 | J. Infect. | pmid:11243757 |
Hofstetter A | [Treatment of chlamydial urethroadnexitis with erythromycin (author's transl)]. | 1979 | MMW Munch Med Wochenschr | pmid:112423 |
Hashimoto N et al. | Effect of erythromycin on matrix metalloproteinase-9 and cell migration. | 2001 | J. Lab. Clin. Med. | pmid:11241027 |
Labro MT and Abdelghaffar H | Immunomodulation by macrolide antibiotics. | 2001 | J Chemother | pmid:11233797 |
Pfeifer BA et al. | Biosynthesis of complex polyketides in a metabolically engineered strain of E. coli. | 2001 | Science | pmid:11230695 |
Alimchandani A and Pai-dhungat JV | A study of gastric emptying in chronic renal failure. | 1997 | J Assoc Physicians India | pmid:11229179 |
van der Toorn F and Lumeij JT | [Streptococcus gallolyticus infections in racing pigeons, a literature review]. | 2001 | Tijdschr Diergeneeskd | pmid:11227399 |
de Dios GarcÃa-DÃaz J et al. | [Phlebitis due to intravenous administration of macrolide antibiotics. A comparative study of erythromycin versus clarithromycin]. | 2001 | Med Clin (Barc) | pmid:11222159 |