erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Liver Cirrhosis, Biliary D008105 12 associated lipids
Liver Diseases D008107 31 associated lipids
Long QT Syndrome D008133 10 associated lipids
Lung Diseases D008171 37 associated lipids
Lung Diseases, Obstructive D008173 10 associated lipids
Lung Neoplasms D008175 171 associated lipids
Lupus Erythematosus, Cutaneous D008178 2 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lyme Disease D008193 5 associated lipids
Lymphadenitis D008199 8 associated lipids
Lymphangitis D008205 4 associated lipids
Lymphogranuloma Venereum D008219 4 associated lipids
Mycetoma D008271 4 associated lipids
Marfan Syndrome D008382 2 associated lipids
Mastoiditis D008417 2 associated lipids
Maxillofacial Injuries D008446 1 associated lipids
Megacolon D008531 1 associated lipids
Meningitis, Haemophilus D008583 3 associated lipids
Meningitis, Listeria D008584 1 associated lipids
Microphthalmos D008850 1 associated lipids
Stomatognathic Diseases D009057 1 associated lipids
Multiple Myeloma D009101 13 associated lipids
Myasthenia Gravis D009157 5 associated lipids
Mycobacterium Infections, Nontuberculous D009165 8 associated lipids
Mycoplasma Infections D009175 13 associated lipids
Mycoplasmatales Infections D009180 6 associated lipids
Myiasis D009198 1 associated lipids
Nasal Polyps D009298 26 associated lipids
Nasopharyngeal Diseases D009302 2 associated lipids
Nasopharyngitis D009304 2 associated lipids
Nausea D009325 7 associated lipids
Nephritis, Interstitial D009395 10 associated lipids
Nervous System Diseases D009422 37 associated lipids
Hereditary Sensory and Autonomic Neuropathies D009477 1 associated lipids
Neutropenia D009503 15 associated lipids
Nocardia Infections D009617 6 associated lipids
Obesity D009765 29 associated lipids
Endophthalmitis D009877 12 associated lipids
Ophthalmia Neonatorum D009878 1 associated lipids
Psittacosis D009956 4 associated lipids
Orthomyxoviridae Infections D009976 3 associated lipids
Osteitis D010000 10 associated lipids
Osteolysis D010014 8 associated lipids
Osteomyelitis D010019 10 associated lipids
Otitis D010031 5 associated lipids
Otitis Externa D010032 8 associated lipids
Otitis Media D010033 12 associated lipids
Otitis Media with Effusion D010034 9 associated lipids
Otitis Media, Suppurative D010035 4 associated lipids
Otorhinolaryngologic Diseases D010038 3 associated lipids
Per page 10 20 50 100 | Total 442

PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with erythromycin

Download all related citations
Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Trepanier LA and Miller JL NADH-dependent reduction of sulphamethoxazole hydroxylamine in dog and human liver microsomes. 2000 Xenobiotica pmid:11307968
Milne RW et al. Hepatic disposition of fexofenadine: influence of the transport inhibitors erythromycin and dibromosulphothalein. 2000 Pharm. Res. pmid:11303961
McGee L et al. Serotype 19f multiresistant pneumococcal clone harboring two erythromycin resistance determinants (erm(B) and mef(A)) in South Africa. 2001 Antimicrob. Agents Chemother. pmid:11302838
Ip M et al. Macrolide resistance in Streptococcus pneumoniae in Hong Kong. 2001 Antimicrob. Agents Chemother. pmid:11302833
Tsunoda SM et al. Preliminary evaluation of progestins as inducers of cytochrome P450 3A4 activity in postmenopausal women. 1998 J Clin Pharmacol pmid:11301566
Gunics G et al. Enhanced antibacterial effect of erythromycin in the presence of 3,5-dibenzoyl-1,4-dihydropyridines. 2001 Jan-Feb Anticancer Res. pmid:11299745
Craft JC ABT-773 overview. 2001 Jpn J Antibiot pmid:11296410
Kanazawa S et al. The effects of grapefruit juice on the pharmacokinetics of erythromycin. 2001 Jan-Feb Eur. J. Clin. Pharmacol. pmid:11294369
Kenyon SL et al. Broad-spectrum antibiotics for spontaneous preterm labour: the ORACLE II randomised trial. ORACLE Collaborative Group. 2001 Lancet pmid:11293641
Kenyon SL et al. Broad-spectrum antibiotics for preterm, prelabour rupture of fetal membranes: the ORACLE I randomised trial. ORACLE Collaborative Group. 2001 Lancet pmid:11293640
Queille-Roussel C et al. Comparison of the cumulative irritation potential of adapalene gel and cream with that of erythromycin/tretinoin solution and gel and erythromycin/isotretinoin gel. 2001 Clin Ther pmid:11293554
Ueno N et al. Erythromycin administration before sleep is effective in decreasing fasting hyperglycemia in type 2 diabetic patients. 2001 Diabetes Care pmid:11289494
Ge N et al. Interferon-gamma activates outwardly rectifying chloride channels in the human bronchial epithelial cell line BEAS-2B. 2001 J. Med. Invest. pmid:11286023
Bryskier A Ketolides-telithromycin, an example of a new class of antibacterial agents. 2000 Clin. Microbiol. Infect. pmid:11284926
Kanellopoulou M et al. Isolation rate, T-serotyping and susceptibility to antibiotics of Group A Streptococcus from pediatric infections in Athens. 2000 Clin. Microbiol. Infect. pmid:11284924
Osato MS et al. Comparative efficacy of new investigational agents against Helicobacter pylori. 2001 Aliment. Pharmacol. Ther. pmid:11284777
Montanari MP et al. Differentiation of resistance phenotypes among erythromycin-resistant Pneumococci. 2001 J. Clin. Microbiol. pmid:11283047
Vela AI et al. Antimicrobial susceptibility of Listeria monocytogenes isolated from meningoencephalitis in sheep. 2001 Int. J. Antimicrob. Agents pmid:11282267
Zouain MG and Araj GF Antimicrobial resistance of Enterococci in Lebanon. 2001 Int. J. Antimicrob. Agents pmid:11282266
Ioannidou S et al. Antibiotic resistance rates and macrolide resistance phenotypes of viridans group streptococci from the oropharynx of healthy Greek children. 2001 Int. J. Antimicrob. Agents pmid:11282264
Leyden JJ et al. The efficacy and safety of a combination benzoyl peroxide/clindamycin topical gel compared with benzoyl peroxide alone and a benzoyl peroxide/erythromycin combination product. 2001 Jan-Feb J Cutan Med Surg pmid:11281433
Papudesu B et al. Invasive pneumococcal disease. 2001 Med Health R I pmid:11280137
Steigbigel RT et al. Antibiotic combinations in the treatment of experimental Staphylococcus aureus infection. 1975 J. Infect. Dis. pmid:1127254
Avanzini C et al. Streptococcus pyogenes collected in Torino (northwest Italy) between 1983 and 1998: survey of macrolide resistance and trend of genotype by RAPD. 2000 Microb. Drug Resist. pmid:11272257
Ye H et al. Antimycoplasmal activities of (S)-(-)-9-fluoro-2,3-dihydro-3-methyl-10 -[4-(2-pyridyl)-1-piperazinyl]-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine -6-carboxylic acid (YH-6) in comparison with other antibiotics in vitro. 1999 Zhongguo Yao Li Xue Bao pmid:11270970
Champney WS and Tober CL Structure-activity relationships for six ketolide antibiotics. 2001 Curr. Microbiol. pmid:11270656
Cervin A The anti-inflammatory effect of erythromycin and its derivatives, with special reference to nasal polyposis and chronic sinusitis. 2001 Acta Otolaryngol. pmid:11270500
Schwartz JB Race but not age affects erythromycin breath test results in older hypertensive men. 2001 J Clin Pharmacol pmid:11269573
Sanz E et al. Perception of teratogenic risk of common medicines. 2001 Eur. J. Obstet. Gynecol. Reprod. Biol. pmid:11267734
Lunzer MR et al. Jaundice due to erythromycin estolate. 1975 Gastroenterology pmid:1126604
Oliva Rodríguez-Pastor S et al. [Erythromycin and hypertrophic stenosis of the pylorus]. 2001 An. Esp. Pediatr. pmid:11262265
Yamano K et al. Prediction of midazolam-CYP3A inhibitors interaction in the human liver from in vivo/in vitro absorption, distribution, and metabolism data. 2001 Drug Metab. Dispos. pmid:11259329
Koeck JL et al. [First confirmed case of laryngeal diphtheria in Djibouti]. 2000 Med Trop (Mars) pmid:11258062
Perreten V et al. Mdt(A), a new efflux protein conferring multiple antibiotic resistance in Lactococcus lactis and Escherichia coli. 2001 Antimicrob. Agents Chemother. pmid:11257023
Nait-Kaci S et al. [Sensitivity to beta lactams and macrolides of Streptococcus pyogenes isolated at the services from 1994 to 1998]. 1998 Arch Inst Pasteur Alger pmid:11256303
Fernández-Roblas R et al. The bactericidal activities of HMR 3004, HMR 3647 and erythromycin against gram-positive bacilli and development of resistance. 1999 J. Antimicrob. Chemother. pmid:11252337
Bergogne-Bérézin E and Bryskier A The suppository form of antibiotic administration: pharmacokinetics and clinical application. 1999 J. Antimicrob. Chemother. pmid:11252322
Ross JI et al. Phenotypic and genotypic characterization of antibiotic-resistant Propionibacterium acnes isolated from acne patients attending dermatology clinics in Europe, the U.S.A., Japan and Australia. 2001 Br. J. Dermatol. pmid:11251569
Wagner CM The care and management of pertussis in pediatric patients. 2001 Mar-Apr Air Med. J. pmid:11250611
Hladka OA and Motyka OI [Formation of erythromycin resistance in Corynebacterium diphtheriae induced by long-term effect of the antibiotic]. 2000 Sep-Oct Mikrobiol. Z. pmid:11247343
Stamos G et al. Emergence of group A beta-hemolytic streptococci resistant to erythromycin in Athens, Greece. 2001 Eur. J. Clin. Microbiol. Infect. Dis. pmid:11245331
Uh Y et al. Emerging erythromycin resistance among group B streptococci in Korea. 2001 Eur. J. Clin. Microbiol. Infect. Dis. pmid:11245325
Nasser AA and Bizri AR Chronic scalp wound infection due to Rhodococcus equi in an immunocompetent patient. 2001 J. Infect. pmid:11243757
Hofstetter A [Treatment of chlamydial urethroadnexitis with erythromycin (author's transl)]. 1979 MMW Munch Med Wochenschr pmid:112423
Hashimoto N et al. Effect of erythromycin on matrix metalloproteinase-9 and cell migration. 2001 J. Lab. Clin. Med. pmid:11241027
Labro MT and Abdelghaffar H Immunomodulation by macrolide antibiotics. 2001 J Chemother pmid:11233797
Pfeifer BA et al. Biosynthesis of complex polyketides in a metabolically engineered strain of E. coli. 2001 Science pmid:11230695
Alimchandani A and Pai-dhungat JV A study of gastric emptying in chronic renal failure. 1997 J Assoc Physicians India pmid:11229179
van der Toorn F and Lumeij JT [Streptococcus gallolyticus infections in racing pigeons, a literature review]. 2001 Tijdschr Diergeneeskd pmid:11227399
de Dios García-Díaz J et al. [Phlebitis due to intravenous administration of macrolide antibiotics. A comparative study of erythromycin versus clarithromycin]. 2001 Med Clin (Barc) pmid:11222159