erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Eisenberg VH et al. | Legionnaire's disease during pregnancy: a case presentation and review of the literature. | 1997 | Eur. J. Obstet. Gynecol. Reprod. Biol. | pmid:9076416 |
| Pehl C et al. | Effect of erythromycin on postprandial gastroesophageal reflux in reflux esophagitis. | 1997 | Dis. Esophagus | pmid:9079271 |
| Hoppe JE | [Whooping cough in pregnant patients and newborn infants]. | 1996 Nov-Dec | Z Geburtshilfe Neonatol | pmid:9081753 |
| Walz A et al. | Excellent activity of newer quinolones on Legionella pneumophila in J774 macrophages. | 1997 | Zentralbl. Bakteriol. | pmid:9084116 |
| al-Humayyd MS | Pharmacokinetic interactions between erythromycin, clarithromycin, roxithromycin and phenytoin in the rat. | 1997 Mar-Apr | Chemotherapy | pmid:9084915 |
| Qadri SM et al. | In vitro activity of quinupristin/dalfopristin, RP59500, against gram-positive clinical isolates. | 1997 Mar-Apr | Chemotherapy | pmid:9084917 |
| Traub WH and Leonhard B | Antibiotic susceptibility of alpha- and nonhemolytic streptococci from patients and healthy adults to 24 antimicrobial drugs. | 1997 Mar-Apr | Chemotherapy | pmid:9084921 |
| Wu JJ et al. | High incidence of erythromycin-resistant streptococci in Taiwan. | 1997 | Antimicrob. Agents Chemother. | pmid:9087502 |
| Konishi T and Nakao M | Antibiotic treatment in mice infected with Japanese Borrelia garinii: efficacy of ceftriaxone for eradicating the infection induced by Ixodes persulcatus tick bites. | 1997 | Microbiol. Immunol. | pmid:9087959 |
| Costa A et al. | In vivo characterization of the colonic prokinetic effect of erythromycin in the rabbit. | 1997 | Pharmacology | pmid:9088039 |
| Sato F et al. | EM574, an erythromycin derivative, is a motilin receptor agonist in the rabbit. | 1997 | Eur. J. Pharmacol. | pmid:9088872 |
| Singh G et al. | An audit of the problems in management of patients with gonorrhoea. | 1997 | Int J STD AIDS | pmid:9089036 |
| Lerman SJ | Prevention of rheumatic recurrence in the allergic, rheumatic fever patient. | 1977 | J. Pediatr. | pmid:909037 |
| Wilson WR | Tetracyclines, chloramphenicol, erythromycin, and clindamycin. | 1977 | Mayo Clin. Proc. | pmid:909315 |
| Midolo PD et al. | Bactericidal activity and synergy studies of proton pump inhibitors and antibiotics against Helicobacter pylori in vitro. | 1997 | J. Antimicrob. Chemother. | pmid:9096182 |
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| Monji H et al. | Highly sensitive high-performance liquid chromatographic determination method for a new erythromycin derivative, EM523, and its major metabolites in human plasma and urine using post-column tris(2,2'-bipyridine) ruthenium(III) chemiluminescence detection. | 1997 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:9106057 |
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| Norinder A et al. | Economic analysis of treatment with roxithromycin in comparison with erythromycin in patients with lower respiratory tract infections. | 1997 | Scand. J. Infect. Dis. | pmid:9112304 |
| Watanabe Y et al. | [Relationship between quality and serum level after the oral administration of commercial erythromycin tablets in man (author's transl)]. | 1977 | Yakugaku Zasshi | pmid:911413 |
| Leach AJ et al. | A prospective study of the impact of community-based azithromycin treatment of trachoma on carriage and resistance of Streptococcus pneumoniae. | 1997 | Clin. Infect. Dis. | pmid:9114185 |
| Koley AP et al. | Differential interaction of erythromycin with cytochromes P450 3A1/2 in the endoplasmic reticulum: a CO flash photolysis study. | 1997 | Biochemistry | pmid:9116001 |
| Samsom M et al. | Effects of oral erythromycin on fasting and postprandial antroduodenal motility in patients with type I diabetes, measured with an ambulatory manometric technique. | 1997 | Diabetes Care | pmid:9118759 |
| Atorvastatin--a new lipid-lowering drug. | 1997 | Med Lett Drugs Ther | pmid:9121394 | |
| Müller M et al. | Characterization of peripheral-compartment kinetics of antibiotics by in vivo microdialysis in humans. | 1996 | Antimicrob. Agents Chemother. | pmid:9124826 |
| Roord JJ et al. | Prospective open randomized study comparing efficacies and safeties of a 3-day course of azithromycin and a 10-day course of erythromycin in children with community-acquired acute lower respiratory tract infections. | 1996 | Antimicrob. Agents Chemother. | pmid:9124837 |
| Muranaka H et al. | Superoxide scavenging activity of erythromycin-iron complex. | 1997 | Biochem. Biophys. Res. Commun. | pmid:9125127 |
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| Jones RN and Biedenbach DJ | Antimicrobial activity of RU-66647, a new ketolide. | 1997 Jan-Feb | Diagn. Microbiol. Infect. Dis. | pmid:9127099 |
| Nakagawa A et al. | A search for Pseudomonas alginate biosynthesis inhibitors from microbial metabolites. | 1997 | J. Antibiot. | pmid:9127207 |
| Furuya E | Removal of interference by erythromycin, phenazopyridine, and methenamine mandelate in the Porter-Silber reaction. | 1977 | Clin. Chem. | pmid:912880 |
| van Holten J et al. | Neonatal Borrelia duttoni infection: a report of three cases. | 1997 | Trop Doct | pmid:9133806 |
| Winkler M et al. | [Incidence of inflammatory placental changes in threatened premature labor with and without additional antibiotic therapy]. | 1997 | Zentralbl Gynakol | pmid:9139498 |
| Ye Z and Van Dyke K | Interaction of artemisinin and tetracycline or erythromycin against Plasmodium falciparum in vitro. | 1994 | Parasite | pmid:9140487 |
| Florez C et al. | Susceptibilities of 55 strains of Neisseria meningitidis isolated in Spain in 1993 and 1994. | 1997 May-Jun | Chemotherapy | pmid:9142456 |
| GarcÃa-Martos P et al. | Increase in high resistance to penicillin of clinical isolates of Streptococcus pneumoniae in Cádiz, Spain. | 1997 May-Jun | Chemotherapy | pmid:9142458 |
| Tanaka T et al. | A new method to measure gastric emptying in conscious dogs: a validity study and effects of EM523 and L-NNA. | 1997 | Am. J. Physiol. | pmid:9142925 |
| Knothe H | Medical implications of macrolide resistance and its relationship to the use of tylosin in animal feeds. | 1977 | Infection | pmid:914361 |
| Cucchiara S et al. | Antroduodenal motor effects of intravenous erythromycin in children with abnormalities of gastrointestinal motility. | 1997 | J. Pediatr. Gastroenterol. Nutr. | pmid:9144124 |
| Tsuruta S et al. | Effects of erythromycin, clarithromycin and rokitamycin on nifedipine metabolism in rats. | 1997 | Biol. Pharm. Bull. | pmid:9145220 |
| Ng PC et al. | Erythromycin treatment for gastrointestinal dysmotility in preterm infants. | 1997 | J Paediatr Child Health | pmid:9145359 |
| Wise R et al. | The activity of the methylpiperazinyl fluoroquinolone CG 5501: a comparison with other fluoroquinolones. | 1997 | J. Antimicrob. Chemother. | pmid:9145816 |
| Sturm AW et al. | Over-the-counter availability of antimicrobial agents, self-medication and patterns of resistance in Karachi, Pakistan. | 1997 | J. Antimicrob. Chemother. | pmid:9145830 |
| Ednie LM et al. | Susceptibilities of 228 penicillin- and erythromycin-susceptible and -resistant pneumococci to RU 64004, a new ketolide, compared with susceptibilities to 16 other agents. | 1997 | Antimicrob. Agents Chemother. | pmid:9145864 |