erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- Clin. Infect. Dis. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Rampe D and Murawsky MK | Blockade of the human cardiac K+ channel Kv1.5 by the antibiotic erythromycin. | 1997 | Naunyn Schmiedebergs Arch. Pharmacol. | pmid:9205959 |
| Gleason PP et al. | Medical outcomes and antimicrobial costs with the use of the American Thoracic Society guidelines for outpatients with community-acquired pneumonia. | 1997 | JAMA | pmid:9207335 |
| Lagasse JP et al. | [Acute reversible pan-dysautonomia: effect of erythromycin on gastrointestinal involvement]. | 1997 | Gastroenterol. Clin. Biol. | pmid:9208000 |
| Vagliasindi M | Use of flurythromycin ethylsuccinate in infections of lower airways due to sensitive germs: multicenter comparative study with clarithromycin. | 1997 | Int J Clin Pharmacol Ther | pmid:9208340 |
| Nakamura A | [Prevalence of antimicrobial resistance among clinical isolates of Streptococcus pneumoniae in a children's hospital]. | 1997 | Kansenshogaku Zasshi | pmid:9209123 |
| Nakata K et al. | [Suppressive effect of clarithromycin on the production of verotoxin by E. coli O157]. | 1997 | Kansenshogaku Zasshi | pmid:9209125 |
| Kluger MT | Erythromycin--a pro-kinetic and pro-arrhythmogenic agent. | 1997 | Anaesth Intensive Care | pmid:9209631 |
| Itoh Z | Motilin and clinical application. | 1997 | Peptides | pmid:9210180 |
| Tenson T et al. | Erythromycin resistance peptides selected from random peptide libraries. | 1997 | J. Biol. Chem. | pmid:9211885 |
| Kudoh S | [Pathophysiology of diffuse panbronchiolitis and progress of the therapy]. | 1996 | Nihon Kyobu Shikkan Gakkai Zasshi | pmid:9216178 |
| Brand RM et al. | Transdermal delivery of erythromycin lactobionate--implications for the therapy of gastroparesis. | 1997 | Aliment. Pharmacol. Ther. | pmid:9218087 |
| Annese V et al. | Cisapride and erythromycin prokinetic effects in gastroparesis due to type 1 (insulin-dependent) diabetes mellitus. | 1997 | Aliment. Pharmacol. Ther. | pmid:9218089 |
| Hoppe JE and Tschirner T | Comparison of Etest and agar dilution for testing the activity of three macrolides against Bordetella parapertussis. | 1997 | Diagn. Microbiol. Infect. Dis. | pmid:9218920 |
| Antsaklis A et al. | Erythromycin treatment for subclinical Ureaplasma urealyticum infection in preterm labor. | 1997 Mar-Apr | Fetal. Diagn. Ther. | pmid:9218948 |
| Jacobsen JR et al. | Precursor-directed biosynthesis of erythromycin analogs by an engineered polyketide synthase. | 1997 | Science | pmid:9219693 |
| Hanson MR and Bogorad L | Effects of erythromycin on membrane-bound chloroplast ribosomes from wild-type Chlamydomonas reinhardi and erythromycin-resistant mutants. | 1977 | Biochim. Biophys. Acta | pmid:921999 |
| Gaudreau C and Gilbert H | Comparison of disc diffusion and agar dilution methods for antibiotic susceptibility testing of Campylobacter jejuni subsp. jejuni and Campylobacter coli. | 1997 | J. Antimicrob. Chemother. | pmid:9222038 |
| Onody C et al. | Lack of resistance to erythromycin, rifampicin and ciprofloxacin in 98 clinical isolates of Legionella pneumophila. | 1997 | J. Antimicrob. Chemother. | pmid:9222053 |
| Sefton AM et al. | The in-vitro activity of trovafloxacin, a new fluoroquinolone, against Gram-positive bacteria. | 1997 | J. Antimicrob. Chemother. | pmid:9222071 |
| Handsfield HH | Azithromycin in gonorrhoea. | 1997 | Int J STD AIDS | pmid:9228599 |
| Kobayashi T et al. | Ototoxic effect of erythromycin on cochlear potentials in the guinea pig. | 1997 | Ann. Otol. Rhinol. Laryngol. | pmid:9228863 |
| Takizawa H et al. | Erythromycin modulates IL-8 expression in normal and inflamed human bronchial epithelial cells. | 1997 | Am. J. Respir. Crit. Care Med. | pmid:9230759 |
| Fisman S et al. | Erythromycin interaction with risperidone or clomipramine in an adolescent. | 1996 | J Child Adolesc Psychopharmacol | pmid:9231305 |
| Oesterheld JR | Erythromycin and clomipramine: noncompetitive inhibition of demethylation. | 1996 | J Child Adolesc Psychopharmacol | pmid:9231314 |
| Seppälä H et al. | Erythromycin resistance of group A streptococci from throat samples is related to age. | 1997 | Pediatr. Infect. Dis. J. | pmid:9239768 |
| Herdy GV et al. | [Secondary prophylaxis in rheumatic fever. Oral antibiotic therapy versus benzathine penicillin]. | 1996 | Arq. Bras. Cardiol. | pmid:9239868 |
| Altomare DF et al. | Oral erythromycin improves gastrointestinal motility and transit after subtotal but not total gastrectomy for cancer. | 1997 | Br J Surg | pmid:9240156 |
| Berk SL | Therapy for severe community-acquired pneumonia. | 1997 | Clin. Infect. Dis. | pmid:9243063 |
| Hofstetter A et al. | [Treatment of chlamydial urethro-adnexitis with erythromycin]. | 1977 | Fortschr. Med. | pmid:924327 |
| Rapoport N et al. | Factors affecting the permeability of Pseudomonas aeruginosa cell walls toward lipophilic compounds: effects of ultrasound and cell age. | 1997 | Arch. Biochem. Biophys. | pmid:9244388 |
| Pereda A et al. | Nucleotide sequence of the ermE distal flank of the erythromycin biosynthesis cluster in Saccharopolyspora erythraea. | 1997 | Gene | pmid:9249068 |
| Bonnefoy A et al. | Ketolides lack inducibility properties of MLS(B) resistance phenotype. | 1997 | J. Antimicrob. Chemother. | pmid:9249208 |
| Barry AL et al. | Macrolide resistance among Streptococcus pneumoniae and Streptococcus pyogenes isolates from out-patients in the USA. | 1997 | J. Antimicrob. Chemother. | pmid:9249220 |
| Seppälä H et al. | The effect of changes in the consumption of macrolide antibiotics on erythromycin resistance in group A streptococci in Finland. Finnish Study Group for Antimicrobial Resistance. | 1997 | N. Engl. J. Med. | pmid:9250845 |
| Swartz MN | Use of antimicrobial agents and drug resistance. | 1997 | N. Engl. J. Med. | pmid:9250853 |
| Ridlen JS et al. | Determination of erythromycin in urine and plasma using microbore liquid chromatography with tris(2,2'-bipyridyl)ruthenium(II) electrogenerated chemiluminescence detection. | 1997 | J. Chromatogr. B Biomed. Sci. Appl. | pmid:9252054 |
| Goossens C et al. | Baboon syndrome. | 1997 | Dermatology (Basel) | pmid:9252782 |
| Peterson LR et al. | Standardization of a preparative ultracentrifuge method for quantitative determination or protein binding of seven antibiotics. | 1977 | J. Infect. Dis. | pmid:925383 |
| Boyer PJ | Outbreak of clinical mastitis in dairy cows following 'blitz' therapy. | 1997 | Vet. Rec. | pmid:9253837 |
| Schugk J et al. | A clinical study of beta-haemolytic groups A, B, C and G streptococcal bacteremia in adults over an 8-year period. | 1997 | Scand. J. Infect. Dis. | pmid:9255881 |
| Baty V et al. | Legionella jordanis pneumonia unresponsive to fluoroquinolones in a non-immunocompromised host. | 1997 | Scand. J. Infect. Dis. | pmid:9255901 |
| Brunke KJ et al. | A technique for the rapid selection of drug-sensitive and auxotrophic mutants of Phycomyces blakesleeanus. | 1977 | J. Gen. Microbiol. | pmid:925680 |
| Rouse MS et al. | Efficacy of azithromycin or clarithromycin for prophylaxis of viridans group streptococcus experimental endocarditis. | 1997 | Antimicrob. Agents Chemother. | pmid:9257739 |
| Fuursted K | Postexposure factors influencing the duration of postantibiotic effect: significance of temperature, pH, cations, and oxygen tension. | 1997 | Antimicrob. Agents Chemother. | pmid:9257743 |
| Ogasawara KK and Goodwin TM | The efficacy of prophylactic erythromycin in preventing vertical transmission of Ureaplasma urealyticum. | 1997 | Am J Perinatol | pmid:9259934 |
| Dajani AS et al. | Prevention of bacterial endocarditis: recommendations by the American Heart Association. | 1997 | J Am Dent Assoc | pmid:9260427 |
| Szklarz GD and Halpert JR | Molecular modeling of cytochrome P450 3A4. | 1997 | J. Comput. Aided Mol. Des. | pmid:9263853 |
| Sorkine P et al. | Gut decontamination reduces bowel ischemia-induced lung injury in rats. | 1997 | Chest | pmid:9266889 |
| Cazzola M et al. | A five-day course of dirithromycin in the treatment of acute exacerbation of severe chronic obstructive pulmonary disease. | 1997 | J Chemother | pmid:9269609 |
| Takahashi Y et al. | Effects of indomethacin, dexamethasone, and erythromycin on endotoxin-induced intraepithelial mucus production of rat nasal epithelium. | 1997 | Ann. Otol. Rhinol. Laryngol. | pmid:9270434 |