erythromycin
erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.
Cross Reference
Introduction
To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with erythromycin?
erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Antimicrob. Agents Chemother. (35)
- J. Antimicrob. Chemother. (18)
- J. Pharmacol. Exp. Ther. (2)
- Others (29)
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with erythromycin
PubChem Associated disorders and diseases
What pathways are associated with erythromycin
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with erythromycin?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with erythromycin?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with erythromycin?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with erythromycin?
Related references are published most in these journals:
- Antimicrob. Agents Chemother. (19)
- J. Antimicrob. Chemother. (10)
- Drug Metab. Dispos. (5)
- Others (29)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with erythromycin?
Mouse Model
Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).
Knock-out
Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with erythromycin
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Yuan H et al. | [The effect of erythromycin on transforming growth factor-β(1) and secretory leukocyte proteinase inhibitor in a rat model of chronic obstructive pulmonary disease]. | 2011 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:22041779 |
| Huang JQ and Xie CM | [The effects of erythromycin on the secretion of tumor necrosis factor-alpha and transforming growth factor-beta1 and expression of connexin 43 in human pleural mesothelial cells]. | 2003 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:12901826 |
| Fan L and Xu J | [Application progress of macrolide sustained therapy for bronchiectasis]. | 2014 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:24694975 |
| Yu L and Ran PX | [Effects of erythromycin on the synthesis of interleukin-8 and gamma-glutamylcysteine synthetase induced by 4-hydroxynonenal in the bronchial epithelial cells]. | 2009 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:19567187 |
| Xiao W et al. | [The imbalance of Th1/Th2 cytokine expression in peripheral blood mononuclear cell from asthmatic patients and the effect of erythromycin on these cytokines]. | 2000 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:11778516 |
| Zhong XN and Guo SM | [An experimental study on pulmonary vascular inflammation in a rat model of chronic bronchitis and emphysema]. | 2006 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:17045040 |
| Liu J et al. | [mRNA expression of basic fibroblast growth factor in the pulmonary tissues from rats repeatedly infected with mycoplasma pneumoniae]. | 1999 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:11775917 |
| Li Y et al. | [The effect of erythromycin on NF-kappa B activation and cytokines mRNA expression in bleomycin-induced pulmonary fibrosis in rats]. | 1999 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:11776779 |
| Tang YC | [Diagnosis and treatment of Legionnaires' disease from opportunistic infection]. | 1987 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:3440298 |
| Lu W et al. | [Analysis of 37 cases of pneumonia of Legionnaires' disease]. | 1997 | Zhonghua Jie He He Hu Xi Za Zhi | pmid:10072832 |