erythromycin

erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out.

Cross Reference

Introduction

To understand associated biological information of erythromycin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with erythromycin?

erythromycin is suspected in Pneumonia, Infection, Gonorrhea, Cystic Fibrosis, Respiratory Tract Infections, Influenza and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with erythromycin

MeSH term MeSH ID Detail
Critical Illness D016638 13 associated lipids
Bursitis D002062 3 associated lipids
Tooth, Impacted D014095 9 associated lipids
Blister D001768 16 associated lipids
Corynebacterium Infections D003354 7 associated lipids
Acute Lung Injury D055371 33 associated lipids
Death, Sudden, Cardiac D016757 12 associated lipids
Rhabdomyolysis D012206 9 associated lipids
Fetal Membranes, Premature Rupture D005322 4 associated lipids
Diarrhea, Infantile D003968 3 associated lipids
Actinomycetales Infections D000193 4 associated lipids
Pneumonia, Bacterial D018410 16 associated lipids
Rosacea D012393 13 associated lipids
Pericarditis D010493 6 associated lipids
Psychoses, Substance-Induced D011605 7 associated lipids
Tachycardia, Ventricular D017180 9 associated lipids
Heart Block D006327 3 associated lipids
Long QT Syndrome D008133 10 associated lipids
Intestinal Pseudo-Obstruction D007418 5 associated lipids
Gonorrhea D006069 7 associated lipids
Hepatitis, Viral, Human D006525 3 associated lipids
Haemophilus Infections D006192 3 associated lipids
Abortion, Spontaneous D000022 12 associated lipids
Esophagitis, Peptic D004942 4 associated lipids
Sigmoid Neoplasms D012811 5 associated lipids
Endometritis D004716 6 associated lipids
Vibrio Infections D014735 5 associated lipids
Keratoconjunctivitis D007637 3 associated lipids
Radiodermatitis D011855 3 associated lipids
Constipation D003248 8 associated lipids
Inappropriate ADH Syndrome D007177 4 associated lipids
Community-Acquired Infections D017714 8 associated lipids
Varicose Ulcer D014647 4 associated lipids
Mycobacterium avium-intracellulare Infection D015270 4 associated lipids
Pityriasis D010915 3 associated lipids
Xerostomia D014987 6 associated lipids
Hand Dermatoses D006229 5 associated lipids
Postoperative Hemorrhage D019106 7 associated lipids
Ergotism D004881 4 associated lipids
Liver Abscess D008100 6 associated lipids
Dysentery, Bacillary D004405 6 associated lipids
Torsades de Pointes D016171 2 associated lipids
Bundle-Branch Block D002037 2 associated lipids
Splenomegaly D013163 4 associated lipids
Aortic Aneurysm D001014 8 associated lipids
Endocarditis D004696 4 associated lipids
Granuloma, Lethal Midline D006103 2 associated lipids
AIDS-Related Opportunistic Infections D017088 9 associated lipids
Enterocolitis, Necrotizing D020345 3 associated lipids
Pleural Effusion, Malignant D016066 6 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with erythromycin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with erythromycin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with erythromycin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with erythromycin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with erythromycin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with erythromycin?

Mouse Model

Mouse Model are used in the study 'In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.' (Falzari K et al., 2005) and Mouse Model are used in the study 'Activity of ABT-773 against Mycobacterium avium complex in the beige mouse model.' (Cynamon MH et al., 2000).

Knock-out

Knock-out are used in the study 'Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening.' (McLaughlin LA et al., 2008).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with erythromycin

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Per page 10 20 50 100 | Total 13660
Authors Title Published Journal PubMed Link
Gaillat J [Objectives for antibiotic therapy in acute exacerbations of chronic bronchitis]. 2001 Presse Med pmid:11721486
Goldschmidt N et al. Compound cardiac toxicity of oral erythromycin and verapamil. 2001 Ann Pharmacother pmid:11724091
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von Eiff C and Peters G Comparative in vitro activity of ABT-773 and two macrolides against staphylococci. 2002 J. Antimicrob. Chemother. pmid:11751787
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Matsuura B et al. Differential determinants for peptide and non-peptidyl ligand binding to the motilin receptor. Critical role of second extracellular loop for peptide binding and action. 2002 J. Biol. Chem. pmid:11781320
Wilkowske CJ and Hermans PE Actions and uses of antimicrobial agents in the treatment of musculoskeletal infections. 1975 Orthop. Clin. North Am. pmid:1178163
Gan G et al. Intestinal absorption and presystemic elimination of the prokinetic agent, EM574, in the rabbit. 2002 J Pharm Sci pmid:11782911
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Hertweck M et al. Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro. 2002 Eur. J. Biochem. pmid:11784311
Shibuya Y et al. The effect of erythromycin on mucociliary transportability and rheology of cystic fibrosis and bronchiectasis sputum. 2001 Respiration pmid:11786718
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Nagai K et al. Susceptibility to telithromycin in 1,011 Streptococcus pyogenes isolates from 10 central and Eastern European countries. 2002 Antimicrob. Agents Chemother. pmid:11796375
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Cid A et al. Recurrent bacteremia caused by Rhodococcus equi in a non-neutropenic patient with acute myeloid leukemia in complete remission. 2002 Haematologica pmid:11801477
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Basak PY et al. The effect of benzoyl peroxide and benzoyl peroxide/erythromycin combination on the antioxidative defence system in papulopustular acne. 2002 Jan-Feb Eur J Dermatol pmid:11809596
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Xuan D et al. Pharmacokinetics of ABT-773, a new semi-synthetic ketolide in neutropenic lung-infected mice: a population approach. 2002 J. Pharm. Pharmacol. pmid:11829132
Visudhiphan P and Chiemchanya S Mima polymorpha ventriculitis in a young infant. Problems in overcoming the infection with erythromycin intraventricularly. 1975 Clin Pediatr (Phila) pmid:1183131
Weitnauer G et al. Analysis of a C-methyltransferase gene (aviG1) involved in avilamycin biosynthesis in Streptomyces viridochromogenes Tü57 and complementation of a Saccharopolyspora erythraea eryBIII mutant by aviG1. 2002 Microbiology (Reading, Engl.) pmid:11832501
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